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Journal Articles

A CpG Methylation Classifier to Predict Relapse in Adults with T-Cell Lymphoblastic Lymphoma

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Xiao-Peng Tian, Ning Su, Liang Wang, Wei-Juan Huang, Yan-Hui Liu, Xi Zhang, Hui-Qiang Huang, Tong-Yu Lin, Shu-Yun Ma, Hui-Lan Rao, Mei Li, Fang Liu, Fen Zhang, Li-Ye Zhong, Li Liang, Xiao-Liang Lan, Juan Li, Bing Liao, Zhi-Hua Li, Qiong-Lan Tang, Qiong Liang, Chun-Kui Shao, Qiong-Li Zhai, Run-Fen Cheng, Qi Sun, Kun Ru, Xia Gu, Xi-Na Lin, Kun Yi, Yue-Rong Shuang, Xiao-Dong Chen, Wei Dong, Cai Sun, Wei Sang, Hui Liu, Zhi-Gang Zhu, Jun Rao, Qiao-Nan Guo, Ying Zhou, Xiang-Ling Meng, Yong Zhu, Chang-Lu Hu, Yi-Rong Jiang, Ying Zhang, Hong-Yi Gao, Wen-Jun He, Zhong-Jun Xia, Xue-Yi Pan, Lan Hai, Guo-Wei Li, Li-Yan Song, Tie-Bang Kang, Dan Xie, Qing-Qing Cai
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (14): 3760–3770.
https://doi.org/10.1158/1078-0432.CCR-19-4207
Published: 15 July 2020
View articletitled, A CpG Methylation Classifier to Predict Relapse in Adults with T-Cell Lymphoblastic Lymphoma
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Includes: Supplementary data
Journal Articles

A First-Time-in-Human Study of GSK2636771, a Phosphoinositide 3 Kinase Beta-Selective Inhibitor, in Patients with Advanced Solid Tumors

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Joaquin Mateo, Gopinath Ganji, Charlotte Lemech, Howard A. Burris, Sae-Won Han, Karen Swales, Shaun Decordova, M. Phillip DeYoung, Deborah A. Smith, Shanker Kalyana-Sundaram, Jiuhua Wu, Monica Motwani, Rakesh Kumar, Jerry M. Tolson, Sun Young Rha, Hyun Cheol Chung, Joseph P. Eder, Sunil Sharma, Yung-Jue Bang, Jeffrey R. Infante, Li Yan, Johann S. de Bono, Hendrik-Tobias Arkenau
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (19): 5981–5992.
https://doi.org/10.1158/1078-0432.CCR-17-0725
Published: 01 October 2017
View articletitled, A First-Time-in-Human Study of GSK2636771, a Phosphoinositide 3 Kinase Beta-Selective Inhibitor, in Patients with Advanced Solid Tumors
Open the PDF for A First-Time-in-Human Study of GSK2636771, a Phosphoinositide 3 Kinase Beta-Selective Inhibitor, in Patients with Advanced Solid Tumors in another window
Includes: Supplementary data
Journal Articles

A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist

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Rebecca Leyland, Amanda Watkins, Kathy A. Mulgrew, Nicholas Holoweckyj, Lisa Bamber, Natalie J. Tigue, Emily Offer, John Andrews, Li Yan, Stefanie Mullins, Michael D. Oberst, Jane Coates Ulrichsen, David A. Leinster, Kelly McGlinchey, Lesley Young, Michelle Morrow, Scott A. Hammond, Philip Mallinder, Athula Herath, Ching Ching Leow, Robert W. Wilkinson, Ross Stewart
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (13): 3416–3427.
https://doi.org/10.1158/1078-0432.CCR-16-2000
Published: 02 July 2017
View articletitled, A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist
Open the PDF for A Novel Murine GITR Ligand Fusion Protein Induces Antitumor Activity as a Monotherapy That Is Further Enhanced in Combination with an OX40 Agonist in another window
Includes: Supplementary data
Journal Articles

The Opposing Function of STAT3 as an Oncoprotein and Tumor Suppressor Is Dictated by the Expression Status of STAT3β in Esophageal Squamous Cell Carcinoma

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Hai-Feng Zhang, Ye Chen, Chengsheng Wu, Zhi-Yong Wu, David J. Tweardy, Abdulraheem Alshareef, Lian-Di Liao, Yu-Jie Xue, Jian-Yi Wu, Bo Chen, Xiu-E Xu, Keshav Gopal, Nidhi Gupta, En-Min Li, Li-Yan Xu, Raymond Lai
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (3): 691–703.
https://doi.org/10.1158/1078-0432.CCR-15-1253
Published: 31 January 2016
View articletitled, The Opposing Function of STAT3 as an Oncoprotein and Tumor Suppressor Is Dictated by the Expression Status of STAT3β in Esophageal Squamous Cell Carcinoma
Open the PDF for The Opposing Function of STAT3 as an Oncoprotein and Tumor Suppressor Is Dictated by the Expression Status of STAT3β in Esophageal Squamous Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Antitumor Activity in RAS-Driven Tumors by Blocking AKT and MEK

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Anthony W. Tolcher, Khurum Khan, Michael Ong, Udai Banerji, Vassiliki Papadimitrakopoulou, David R. Gandara, Amita Patnaik, Richard D. Baird, David Olmos, Christopher R. Garrett, Jeffrey M. Skolnik, Eric H. Rubin, Paul D. Smith, Pearl Huang, Maria Learoyd, Keith A. Shannon, Anne Morosky, Ernestina Tetteh, Ying-Ming Jou, Kyriakos P. Papadopoulos, Victor Moreno, Brianne Kaiser, Timothy A. Yap, Li Yan, Johann S. de Bono
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (4): 739–748.
https://doi.org/10.1158/1078-0432.CCR-14-1901
Published: 16 February 2015
View articletitled, Antitumor Activity in RAS-Driven Tumors by Blocking AKT and MEK
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Includes: Supplementary data
Journal Articles

Interrogating Two Schedules of the AKT Inhibitor MK-2206 in Patients with Advanced Solid Tumors Incorporating Novel Pharmacodynamic and Functional Imaging Biomarkers

Free
Timothy A. Yap, Li Yan, Amita Patnaik, Nina Tunariu, Andrea Biondo, Ivy Fearen, Kyriakos P. Papadopoulos, David Olmos, Richard Baird, Liliana Delgado, Ernestina Tetteh, Robert A. Beckman, Lisa Lupinacci, Ruth Riisnaes, Shaun Decordova, Simon P. Heaton, Karen Swales, Nandita M. deSouza, Martin O. Leach, Michelle D. Garrett, Daniel M. Sullivan, Johann S. de Bono, Anthony W. Tolcher
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (22): 5672–5685.
https://doi.org/10.1158/1078-0432.CCR-14-0868
Published: 13 November 2014
View articletitled, Interrogating Two Schedules of the AKT Inhibitor MK-2206 in Patients with Advanced Solid Tumors Incorporating Novel Pharmacodynamic and Functional Imaging Biomarkers
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Includes: Supplementary data
Journal Articles

The Importance of Protein Kinase A in Prostate Cancer: Relationship to Patient Outcome in Radiation Therapy Oncology Group Trial 92-02

Free
Alan Pollack, Kyounghwa Bae, Li-Yan Khor, Tahseen Al-Saleem, M. Elizabeth Hammond, Varagur Venkatesan, Roger W. Byhardt, Sucha O. Asbell, William U. Shipley, Howard M. Sandler
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (17): 5478–5484.
https://doi.org/10.1158/1078-0432.CCR-08-2704
Published: 31 August 2009
View articletitled, The Importance of Protein Kinase A in Prostate Cancer: Relationship to Patient Outcome in Radiation Therapy Oncology Group Trial 92-02
Open the PDF for The Importance of Protein Kinase A in Prostate Cancer: Relationship to Patient Outcome in Radiation Therapy Oncology Group Trial 92-02 in another window
Includes: Supplementary data
Journal Articles

Anti-EMMPRIN Monoclonal Antibody as a Novel Agent for Therapy of Head and Neck Cancer

Free
Nichole R. Dean, J. Robert Newman, Emily E. Helman, Wenyue Zhang, Seena Safavy, D.M. Weeks, Mark Cunningham, Linda A. Snyder, Yi Tang, Li Yan, Lacey R. McNally, Donald J. Buchsbaum, Eben L. Rosenthal
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (12): 4058–4065.
https://doi.org/10.1158/1078-0432.CCR-09-0212
Published: 15 June 2009
View articletitled, Anti-EMMPRIN Monoclonal Antibody as a Novel Agent for Therapy of Head and Neck Cancer
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Journal Articles

NGALR Is Overexpressed and Regulated by Hypomethylation in Esophageal Squamous Cell Carcinoma

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Lei Cui, Li-Yan Xu, Zhong-Ying Shen, Qian Tao, Shu-Ying Gao, Zhuo Lv, Ze-Peng Du, Wang-Kai Fang, En-Min Li
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (23): 7674–7681.
https://doi.org/10.1158/1078-0432.CCR-08-0420
Published: 01 December 2008
View articletitled, NGALR Is Overexpressed and Regulated by Hypomethylation in Esophageal Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Bcl-2 and Bax Expression Predict Prostate Cancer Outcome in Men Treated with Androgen Deprivation and Radiotherapy on Radiation Therapy Oncology Group Protocol 92-02

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Li Yan Khor, Jennifer Moughan, Tahseen Al-Saleem, Elizabeth H. Hammond, Varagur Venkatesan, Seth A. Rosenthal, Mark A. Ritter, Howard M. Sandler, Gerald E. Hanks, William U. Shipley, Alan Pollack
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (12): 3585–3590.
https://doi.org/10.1158/1078-0432.CCR-06-2972
Published: 15 June 2007
View articletitled, Bcl-2 and Bax Expression Predict Prostate Cancer Outcome in Men Treated with Androgen Deprivation and Radiotherapy on Radiation Therapy Oncology Group Protocol 92-02
Open the PDF for Bcl-2 and Bax Expression Predict Prostate Cancer Outcome in Men Treated with Androgen Deprivation and Radiotherapy on Radiation Therapy Oncology Group Protocol 92-02 in another window
Journal Articles

The Matrix Metalloproteinase-9/Neutrophil Gelatinase-Associated Lipocalin Complex Plays a Role in Breast Tumor Growth and Is Present in the Urine of Breast Cancer Patients

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Cecilia A. Fernández, Li Yan, Gwendolyn Louis, Jiang Yang, Jeffery L. Kutok, Marsha A. Moses
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (15): 5390–5395.
https://doi.org/10.1158/1078-0432.CCR-04-2391
Published: 01 August 2005
View articletitled, The Matrix Metalloproteinase-9/Neutrophil Gelatinase-Associated Lipocalin Complex Plays a Role in Breast Tumor Growth and Is Present in the Urine of Breast Cancer Patients
Open the PDF for The Matrix Metalloproteinase-9/Neutrophil Gelatinase-Associated Lipocalin Complex Plays a Role in Breast Tumor Growth and Is Present in the Urine of Breast Cancer Patients in another window
Journal Articles

Expression Profile of Cancer-Testis Genes in 121 Human Colorectal Cancer Tissue and Adjacent Normal Tissue

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Ming Li, Yan-Hua Yuan, Yan Han, Yue-Xiang Liu, Li Yan, Yu Wang, Jin Gu
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (5): 1809–1814.
https://doi.org/10.1158/1078-0432.CCR-04-1365
Published: 08 March 2005
View articletitled, Expression Profile of Cancer-Testis Genes in 121 Human Colorectal Cancer Tissue and Adjacent Normal Tissue
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