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Lesley-Ann Martin
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Journal Articles

Early Enrichment of ESR1 Mutations and the Impact on Gene Expression in Presurgical Primary Breast Cancer Treated with Aromatase Inhibitors

Mariana Ferreira Leal, Ben P. Haynes, Eugene Schuster, Belinda Yeo, Maria Afentakis, Lila Zabaglo, Vera Martins, Richard Buus, Andrew Dodson, Maggie C.U. Cheang, Ian E. Smith, Lesley-Ann Martin, Mitch Dowsett
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (24): 7485–7496.
https://doi.org/10.1158/1078-0432.CCR-19-1129
Published: 13 December 2019
View article titled, Early Enrichment of ESR1 Mutations and the Impact on Gene Expression in Presurgical Primary Breast Cancer Treated with Aromatase Inhibitors
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Includes: Supplementary data
Journal Articles

Differences in the Transcriptional Response to Fulvestrant and Estrogen Deprivation in ER-Positive Breast Cancer

Neill Patani, Anita K. Dunbier, Helen Anderson, Zara Ghazoui, Ricardo Ribas, Elizabeth Anderson, Qiong Gao, Roger A'hern, Alan Mackay, Justin Lindemann, Robert Wellings, Jill Walker, Irene Kuter, Lesley-Ann Martin, Mitch Dowsett
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (15): 3962–3973.
https://doi.org/10.1158/1078-0432.CCR-13-1378
Published: 31 July 2014
View article titled, Differences in the Transcriptional Response to Fulvestrant and Estrogen Deprivation in ER-Positive Breast Cancer
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Includes: Supplementary data
Journal Articles

Effect of Aromatase Inhibition on Functional Gene Modules in Estrogen Receptor–Positive Breast Cancer and Their Relationship with Antiproliferative Response

Qiong Gao, Neill Patani, Anita K. Dunbier, Zara Ghazoui, Marketa Zvelebil, Lesley-Ann Martin, Mitch Dowsett
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2014) 20 (9): 2485–2494.
https://doi.org/10.1158/1078-0432.CCR-13-2602
Published: 30 April 2014
View article titled, Effect of Aromatase Inhibition on Functional Gene Modules in Estrogen Receptor–Positive Breast Cancer and Their Relationship with Antiproliferative Response
Open the PDF for Effect of Aromatase Inhibition on Functional Gene Modules in Estrogen Receptor–Positive Breast Cancer and Their Relationship with Antiproliferative Response in another window
Includes: Supplementary data
Journal Articles

Biological Evidence for Dual Antiangiogenic-Antiaromatase Activity of the VEGFR Inhibitor PTK787/ZK222584 In vivo

Susana Banerjee, Roger A'Hern, Simone Detre, Amanda J. Littlewood-Evans, Dean B. Evans, Mitchell Dowsett, Lesley-Ann Martin
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (16): 4178–4187.
https://doi.org/10.1158/1078-0432.CCR-10-0456
Published: 11 August 2010
View article titled, Biological Evidence for Dual Antiangiogenic-Antiaromatase Activity of the VEGFR Inhibitor PTK787/ZK222584 <em>In vivo</em>
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Includes: Supplementary data
Journal Articles

Lapatinib Restores Hormone Sensitivity with Differential Effects on Estrogen Receptor Signaling in Cell Models of Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer with Acquired Endocrine Resistance

Alexandra F. Leary, Suzanne Drury, Simone Detre, Sunil Pancholi, Anne E. Lykkesfeldt, Lesley-Ann Martin, Mitch Dowsett, Stephen R.D. Johnston
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (5): 1486–1497.
https://doi.org/10.1158/1078-0432.CCR-09-1764
Published: 28 February 2010
View article titled, Lapatinib Restores Hormone Sensitivity with Differential Effects on Estrogen Receptor Signaling in Cell Models of Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer with Acquired Endocrine Resistance
Open the PDF for Lapatinib Restores Hormone Sensitivity with Differential Effects on Estrogen Receptor Signaling in Cell Models of Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer with Acquired Endocrine Resistance in another window
Includes: Supplementary data
Journal Articles

The Effects of Neoadjuvant Anastrozole and Tamoxifen on Circulating Vascular Endothelial Growth Factor and Soluble Vascular Endothelial Growth Factor Receptor 1 in Breast Cancer

Susana Banerjee, Sunil Pancholi, Roger A'Hern, Zara Ghazoui, Ian E. Smith, Mitch Dowsett, Lesley-Ann Martin
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (9): 2656–2663.
https://doi.org/10.1158/1078-0432.CCR-07-1352
Published: 01 May 2008
View article titled, The Effects of Neoadjuvant Anastrozole and Tamoxifen on Circulating Vascular Endothelial Growth Factor and Soluble Vascular Endothelial Growth Factor Receptor 1 in Breast Cancer
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Journal Articles

Correlation between Cyclooxygenase-2 Expression and Angiogenesis in Human Breast Cancer

Giles Davies, Janine Salter, Margaret Hills, Lesley-Ann Martin, Nigel Sacks, Mitch Dowsett
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (7): 2651–2656.
Published: 01 July 2003
View article titled, Correlation between Cyclooxygenase-2 Expression and Angiogenesis in Human Breast Cancer
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Journal Articles

Integration of Signal Transduction Inhibitors with Endocrine Therapy: An Approach to Overcoming Hormone Resistance in Breast Cancer

Stephen R. D. Johnston, Julia Head, Sunil Pancholi, Simone Detre, Lesley-Ann Martin, Ian E. Smith, Mitch Dowsett
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (1): 524s–532s.
Published: 01 January 2003
View article titled, Integration of Signal Transduction Inhibitors with Endocrine Therapy: <subtitle>An Approach to Overcoming Hormone Resistance in Breast Cancer</subtitle>
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