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Lawrence D. True
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Journal Articles

Framework for the Pathology Workup of Metastatic Castration-Resistant Prostate Cancer Biopsies

Michael C. Haffner, Michael J. Morris, Chien-Kuang C. Ding, Erolcan Sayar, Rohit Mehra, Brian Robinson, Lawrence D. True, Martin Gleave, Tamara L. Lotan, Rahul Aggarwal, Jiaoti Huang, Massimo Loda, Peter S. Nelson, Mark A. Rubin, Himisha Beltran
Journal: Clinical Cancer Research
Clin Cancer Res (2024)
https://doi.org/10.1158/1078-0432.CCR-24-2061
Published: 26 November 2024
View article titled, Framework for the Pathology Workup of Metastatic Castration-Resistant Prostate Cancer Biopsies
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Includes: Supplementary data
Journal Articles

Assessment of Androgen Receptor Splice Variant-7 as a Biomarker of Clinical Response in Castration-Sensitive Prostate Cancer

Adam G. Sowalsky, Ines Figueiredo, Rosina T. Lis, Ilsa Coleman, Bora Gurel, Denisa Bogdan, Wei Yuan, Joshua W. Russo, John R. Bright, Nichelle C. Whitlock, Shana Y. Trostel, Anson T. Ku, Radhika A. Patel, Lawrence D. True, Jonathan Welti, Juan M. Jimenez-Vacas, Daniel Nava Rodrigues, Ruth Riisnaes, Antje Neeb, Cynthia T. Sprenger, Amanda Swain, Scott Wilkinson, Fatima Karzai, William L. Dahut, Steven P. Balk, Eva Corey, Peter S. Nelson, Michael C. Haffner, Stephen R. Plymate, Johann S. de Bono, Adam Sharp
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (16): 3509–3525.
https://doi.org/10.1158/1078-0432.CCR-22-0851
Published: 15 August 2022
View article titled, Assessment of Androgen Receptor Splice Variant-7 as a Biomarker of Clinical Response in Castration-Sensitive Prostate Cancer
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Includes: Supplementary data
Journal Articles

Pathology: Hub and Integrator of Modern, Multidisciplinary [Precision] Oncology

The AACR Pathology Task Force, Carolyn C. Compton, Angelo M. De Marzo, Jayanta Debnath, Keith D. Eaton, Kojo Elenitoba-Johnson, Michelangelo Fiorentino, Christopher A. French, Thomas J. Fuchs, Felice Giangaspero, Jiaoti Huang, A. John Iafrate, Michael M. Ittmann, Roy A. Jensen, Annette S. Kim, Massimo Loda, Robin G. Lorenz, Tamara L. Lotan, Anirban Maitra, Gerrit A. Meijer, Richard N. Mitchell, Anil V. Parwani, Francesco Pezzella, Eli Pikarsky, Jorge S. Reis-Filho, Andrea L. Richardson, Mark A. Rubin, Lawrence D. True
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (2): 265–270.
https://doi.org/10.1158/1078-0432.CCR-21-1206
Published: 19 January 2022
View article titled, Pathology: Hub and Integrator of Modern, Multidisciplinary [Precision] Oncology
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Journal Articles

How Accurately does PSMA Inhibitor 18F-DCFPyL-PET-CT Image Prostate Cancer?

Lawrence D. True, Delphine L. Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (13): 3512–3514.
https://doi.org/10.1158/1078-0432.CCR-21-0749
Published: 01 July 2021
View article titled, How Accurately does PSMA Inhibitor 18F-DCFPyL-PET-CT Image Prostate Cancer?
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Journal Articles

Regulation of CEACAM5 and Therapeutic Efficacy of an Anti-CEACAM5–SN38 Antibody–drug Conjugate in Neuroendocrine Prostate Cancer

Diana C. DeLucia, Thomas M. Cardillo, Lisa Ang, Mark P. Labrecque, Ailin Zhang, James E. Hopkins, Navonil De Sarkar, Ilsa Coleman, Rui M. Gil da Costa, Eva Corey, Lawrence D. True, Michael C. Haffner, Michael T. Schweizer, Colm Morrissey, Peter S. Nelson, John K. Lee
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (3): 759–774.
https://doi.org/10.1158/1078-0432.CCR-20-3396
Published: 01 February 2021
View article titled, Regulation of CEACAM5 and Therapeutic Efficacy of an Anti-CEACAM5–SN38 Antibody–drug Conjugate in Neuroendocrine Prostate Cancer
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Includes: Supplementary data
Journal Articles

Identification of Therapeutic Vulnerabilities in Small-cell Neuroendocrine Prostate Cancer

Alexandra N. Corella, Ma Victoria Andrea Cabiliza Ordonio, Ilsa Coleman, Jared M. Lucas, Arja Kaipainen, Holly M. Nguyen, Daniel Sondheim, Lisha G. Brown, Lawrence D. True, John K. Lee, David MacPherson, Paul Nghiem, Roman Gulati, Colm Morrissey, Eva Corey, Peter S. Nelson
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (7): 1667–1677.
https://doi.org/10.1158/1078-0432.CCR-19-0775
Published: 01 April 2020
View article titled, Identification of Therapeutic Vulnerabilities in Small-cell Neuroendocrine Prostate Cancer
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Includes: Supplementary data
Journal Articles

Contribution of Adrenal Glands to Intratumor Androgens and Growth of Castration-Resistant Prostate Cancer

Elahe A. Mostaghel, Ailin Zhang, Susana Hernandez, Brett T. Marck, Xiaotun Zhang, Daniel Tamae, Heather E. Biehl, Maria Tretiakova, Jon Bartlett, John Burns, Ruth Dumpit, Lisa Ang, Alvin M. Matsumoto, Trevor M. Penning, Steven P. Balk, Colm Morrissey, Eva Corey, Lawrence D. True, Peter S. Nelson
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (1): 426–439.
https://doi.org/10.1158/1078-0432.CCR-18-1431
Published: 03 January 2019
View article titled, Contribution of Adrenal Glands to Intratumor Androgens and Growth of Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Association of Tissue Abiraterone Levels and SLCO Genotype with Intraprostatic Steroids and Pathologic Response in Men with High-Risk Localized Prostate Cancer

Elahe A. Mostaghel, Eunpi Cho, Ailin Zhang, Mohammad Alyamani, Arja Kaipainen, Sean Green, Brett T. Marck, Nima Sharifi, Jonathan L. Wright, Roman Gulati, Lawrence D. True, Massimo Loda, Alvin M. Matsumoto, Daniel Tamae, Trevor N. Penning, Steven P. Balk, Phillip W. Kantoff, Peter S. Nelson, Mary-Ellen Taplin, R. Bruce Montgomery
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (16): 4592–4601.
https://doi.org/10.1158/1078-0432.CCR-16-2245
Published: 14 August 2017
View article titled, Association of Tissue Abiraterone Levels and <em>SLCO</em> Genotype with Intraprostatic Steroids and Pathologic Response in Men with High-Risk Localized Prostate Cancer
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Includes: Supplementary data
Journal Articles

SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

Xiaotun Zhang, Ilsa M. Coleman, Lisha G. Brown, Lawrence D. True, Lori Kollath, Jared M. Lucas, Hung-Ming Lam, Ruth Dumpit, Eva Corey, Lisly Chéry, Bryce Lakely, Celestia S. Higano, Bruce Montgomery, Martine Roudier, Paul H. Lange, Peter S. Nelson, Robert L. Vessella, Colm Morrissey
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (20): 4698–4708.
https://doi.org/10.1158/1078-0432.CCR-15-0157
Published: 14 October 2015
View article titled, SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Abiraterone Treatment in Castration-Resistant Prostate Cancer Selects for Progesterone Responsive Mutant Androgen Receptors

Eddy J. Chen, Adam G. Sowalsky, Shuai Gao, Changmeng Cai, Olga Voznesensky, Rachel Schaefer, Massimo Loda, Lawrence D. True, Huihui Ye, Patricia Troncoso, Rosina L. Lis, Philip W. Kantoff, Robert B. Montgomery, Peter S. Nelson, Glenn J. Bubley, Steven P. Balk, Mary-Ellen Taplin
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (6): 1273–1280.
https://doi.org/10.1158/1078-0432.CCR-14-1220
Published: 12 March 2015
View article titled, Abiraterone Treatment in Castration-Resistant Prostate Cancer Selects for Progesterone Responsive Mutant Androgen Receptors
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Includes: Supplementary data
Journal Articles

Impact of Preanalytic Factors on the Design and Application of Integral Biomarkers for Directing Patient Therapy

Stephen M. Hewitt, Sunil S. Badve, Lawrence D. True
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (6): 1524–1530.
https://doi.org/10.1158/1078-0432.CCR-11-2204
Published: 14 March 2012
View article titled, Impact of Preanalytic Factors on the Design and Application of Integral Biomarkers for Directing Patient Therapy
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Journal Articles

Differential Gene Expression in Benign Prostate Epithelium of Men with and without Prostate Cancer: Evidence for a Prostate Cancer Field Effect

Michael C. Risk, Beatrice S. Knudsen, Ilsa Coleman, Ruth F. Dumpit, Alan R. Kristal, Nolwenn LeMeur, Robert C. Gentleman, Lawrence D. True, Peter S. Nelson, Daniel W. Lin
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (22): 5414–5423.
https://doi.org/10.1158/1078-0432.CCR-10-0272
Published: 14 November 2010
View article titled, Differential Gene Expression in Benign Prostate Epithelium of Men with and without Prostate Cancer: Evidence for a Prostate Cancer Field Effect
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Includes: Supplementary data
Journal Articles

Guidelines for the Development and Incorporation of Biomarker Studies in Early Clinical Trials of Novel Agents

Janet E. Dancey, Kevin K. Dobbin, Susan Groshen, J. Milburn Jessup, Andrew H. Hruszkewycz, Maria Koehler, Ralph Parchment, Mark J. Ratain, Lalitha K. Shankar, Walter M. Stadler, Lawrence D. True, Amy Gravell, Michael R. Grever
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (6): 1745–1755.
https://doi.org/10.1158/1078-0432.CCR-09-2167
Published: 14 March 2010
View article titled, Guidelines for the Development and Incorporation of Biomarker Studies in Early Clinical Trials of Novel Agents
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Journal Articles

Prostate Cancer–Associated Gene Expression Alterations Determined from Needle Biopsies

David Z. Qian, Chung-Ying Huang, Catherine A. O'Brien, Ilsa M. Coleman, Mark Garzotto, Lawrence D. True, Celestia S. Higano, Robert Vessella, Paul H. Lange, Peter S. Nelson, Tomasz M. Beer
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (9): 3135–3142.
https://doi.org/10.1158/1078-0432.CCR-08-1982
Published: 30 April 2009
View article titled, Prostate Cancer–Associated Gene Expression Alterations Determined from Needle Biopsies
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Includes: Supplementary data
Journal Articles

Tumor Suppressor BRCA1 Is Expressed in Prostate Cancer and Controls Insulin-like Growth Factor I Receptor (IGF-IR) Gene Transcription in an Androgen Receptor–Dependent Manner

Hagit Schayek, Kathy Haugk, Shihua Sun, Lawrence D. True, Stephen R. Plymate, Haim Werner
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (5): 1558–1565.
https://doi.org/10.1158/1078-0432.CCR-08-1440
Published: 27 February 2009
View article titled, Tumor Suppressor BRCA1 Is Expressed in Prostate Cancer and Controls Insulin-like Growth Factor I Receptor (<em>IGF-IR</em>) Gene Transcription in an Androgen Receptor–Dependent Manner
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Journal Articles

WDR19 Expression is Increased in Prostate Cancer Compared with Normal Cells, but Low-Intensity Expression in Cancers is Associated with Shorter Time to Biochemical Failures and Local Recurrence

Biaoyang Lin, Angelita G. Utleg, Karsten Gravdal, James T. White, Ole J. Halvorsen, Wei Lu, Lawrence D. True, Robert Vessella, Paul H. Lange, Peter S. Nelson, Leroy Hood, Karl-Henning Kalland, Lars A. Akslen
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (5): 1397–1406.
https://doi.org/10.1158/1078-0432.CCR-07-1535
Published: 03 March 2008
View article titled, WDR19 Expression is Increased in Prostate Cancer Compared with Normal Cells, but Low-Intensity Expression in Cancers is Associated with Shorter Time to Biochemical Failures and Local Recurrence
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Includes: Supplementary data
Journal Articles

Molecular Alterations in Prostate Carcinomas that Associate with In vivo Exposure to Chemotherapy: Identification of a Cytoprotective Mechanism Involving Growth Differentiation Factor 15

Chung-Ying Huang, Tomasz M. Beer, Celestia S. Higano, Lawrence D. True, Robert Vessella, Paul H. Lange, Mark Garzotto, Peter S. Nelson
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (19): 5825–5833.
https://doi.org/10.1158/1078-0432.CCR-07-1037
Published: 01 October 2007
View article titled, Molecular Alterations in Prostate Carcinomas that Associate with <em>In vivo</em> Exposure to Chemotherapy: Identification of a Cytoprotective Mechanism Involving Growth Differentiation Factor 15
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Includes: Supplementary data
Journal Articles

Differential Expression of Osteonectin/SPARC during Human Prostate Cancer Progression

Regi Thomas, Lawrence D. True, James A. Bassuk, Paul H. Lange, Robert L. Vessella
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (3): 1140–1149.
Published: 01 March 2000
View article titled, Differential Expression of Osteonectin/SPARC during Human Prostate Cancer Progression
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