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L. Jeffrey Medeiros
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Journal Articles

Nine-Year Follow-up of Patients with Relapsed Follicular Lymphoma after Nonmyeloablative Allogeneic Stem Cell Transplant and Autologous Transplant

Issa F. Khouri, Denái R. Milton, Alison M. Gulbis, Elias J. Jabbour, Loretta Nastoupil, Celina Ledesma, Paolo Anderlini, Qaiser Bashir, May Daher, Jin S. Im, Swaminathan P. Iyer, David Marin, Rohtesh S. Mehta, Amanda L. Olson, Uday R. Popat, Muzaffar Qazilbash, Neeraj Saini, Felipe Samaniego, Gabriela Rondon, L. Jeffrey Medeiros, Richard E. Champlin
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (21): 5847–5856.
https://doi.org/10.1158/1078-0432.CCR-21-1377
Published: 01 November 2021
View article titled, Nine-Year Follow-up of Patients with Relapsed Follicular Lymphoma after Nonmyeloablative Allogeneic Stem Cell Transplant and Autologous Transplant
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Journal Articles

Strategic Therapeutic Targeting to Overcome Venetoclax Resistance in Aggressive B-cell Lymphomas

Lan V. Pham, Shengjian Huang, Hui Zhang, Jun Zhang, Taylor Bell, Shouhao Zhou, Elizabeth Pogue, Zhiyong Ding, Laura Lam, Jason Westin, R. Eric Davis, Ken H. Young, L. Jeffrey Medeiros, Richard J. Ford, Krystle Nomie, Leo Zhang, Michael Wang
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (16): 3967–3980.
https://doi.org/10.1158/1078-0432.CCR-17-3004
Published: 14 August 2018
View article titled, Strategic Therapeutic Targeting to Overcome Venetoclax Resistance in Aggressive B-cell Lymphomas
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Includes: Supplementary data
Journal Articles

Updated Results of Rituximab Pre- and Post-BEAM with or without 90Yttrium Ibritumomab Tiuxetan during Autologous Transplant for Diffuse Large B-cell Lymphoma

Jad Chahoud, Dawen Sui, William D. Erwin, Alison M. Gulbis, Martin Korbling, Mingzhi Zhang, Sairah Ahmed, Gheath Alatrash, Paolo Anderlini, Stefan O. Ciurea, Betul Oran, Luis E. Fayad, Roland L. Bassett, Jr, Elias J. Jabbour, L. Jeffrey Medeiros, Homer A. Macapinlac, Ken H. Young, Issa F. Khouri
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (10): 2304–2311.
https://doi.org/10.1158/1078-0432.CCR-17-3561
Published: 14 May 2018
View article titled, Updated Results of Rituximab Pre- and Post-BEAM with or without <sup>90</sup>Yttrium Ibritumomab Tiuxetan during Autologous Transplant for Diffuse Large B-cell Lymphoma
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Includes: Supplementary data
Journal Articles

Validation of Immunohistochemical Assays for Integral Biomarkers in the NCI-MATCH EAY131 Clinical Trial

Joseph D. Khoury, Wei-Lien Wang, Victor G. Prieto, L. Jeffrey Medeiros, Neda Kalhor, Meera Hameed, Russell Broaddus, Stanley R. Hamilton
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (3): 521–531.
https://doi.org/10.1158/1078-0432.CCR-17-1597
Published: 31 January 2018
View article titled, Validation of Immunohistochemical Assays for Integral Biomarkers in the NCI-MATCH EAY131 Clinical Trial
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Includes: Supplementary data
Journal Articles

Clinical and Biologic Significance of MYC Genetic Mutations in De Novo Diffuse Large B-cell Lymphoma

Zijun Y. Xu-Monette, Qipan Deng, Ganiraju C. Manyam, Alexander Tzankov, Ling Li, Yi Xia, Xiao-xiao Wang, Dehui Zou, Carlo Visco, Karen Dybkær, Jun Li, Li Zhang, Han Liang, Santiago Montes-Moreno, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W.L. Choi, J. Han van Krieken, Jooryung Huh, Maurilio Ponzoni, Andrés J.M. Ferreri, Ben M. Parsons, Michael B. Møller, Sa A. Wang, Roberto N. Miranda, Miguel A. Piris, Jane N. Winter, L. Jeffrey Medeiros, Yong Li, Ken H. Young
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (14): 3593–3605.
https://doi.org/10.1158/1078-0432.CCR-15-2296
Published: 14 July 2016
View article titled, Clinical and Biologic Significance of <em>MYC</em> Genetic Mutations in <em>De Novo</em> Diffuse Large B-cell Lymphoma
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Includes: Supplementary data
Journal Articles

Hotspot Mutation Panel Testing Reveals Clonal Evolution in a Study of 265 Paired Primary and Metastatic Tumors

Rashmi S. Goswami, Keyur P. Patel, Rajesh R. Singh, Funda Meric-Bernstam, E. Scott Kopetz, Vivek Subbiah, Ricardo H. Alvarez, Michael A. Davies, Kausar J. Jabbar, Sinchita Roy-Chowdhuri, Alexander J. Lazar, L. Jeffrey Medeiros, Russell R. Broaddus, Rajyalakshmi Luthra, Mark J. Routbort
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (11): 2644–2651.
https://doi.org/10.1158/1078-0432.CCR-14-2391
Published: 31 May 2015
View article titled, Hotspot Mutation Panel Testing Reveals Clonal Evolution in a Study of 265 Paired Primary and Metastatic Tumors
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Includes: Supplementary data
Journal Articles

Clinical Implications of Phosphorylated STAT3 Expression in De Novo Diffuse Large B-cell Lymphoma

Chi Young Ok, Jiayu Chen, Zijun Y. Xu-Monette, Alexandar Tzankov, Ganiraju C. Manyam, Ling Li, Carlo Visco, Santiago Montes-Moreno, Karen Dybkær, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W.L. Choi, J. Han van Krieken, Jooryung Huh, Xiaoying Zhao, Maurilio Ponzoni, Andrés J.M. Ferreri, Francesco Bertoni, John P. Farnen, Michael B. Møller, Miguel A. Piris, Jane N. Winter, L. Jeffrey Medeiros, Ken H. Young
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (19): 5113–5123.
https://doi.org/10.1158/1078-0432.CCR-14-0683
Published: 30 September 2014
View article titled, Clinical Implications of Phosphorylated STAT3 Expression in <em>De Novo</em> Diffuse Large B-cell Lymphoma
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Includes: Supplementary data
Journal Articles

Prevalence and Clinical Implications of Epstein–Barr Virus Infection in De Novo Diffuse Large B-Cell Lymphoma in Western Countries

Chi Young Ok, Ling Li, Zijun Y. Xu-Monette, Carlo Visco, Alexander Tzankov, Ganiraju C. Manyam, Santiago Montes-Moreno, Karen Dybaer, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Jiayu Chen, Kristy L. Richards, Eric D. Hsi, William W. L. Choi, J. Han van Krieken, Jooryung Huh, Weiyun Ai, Maurilio Ponzoni, Andrés J.M. Ferreri, John P. Farnen, Michael B. Møller, Carlo E. Bueso-Ramos, Roberto N. Miranda, Jane N. Winter, Miguel A. Piris, L. Jeffrey Medeiros, Ken H. Young
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (9): 2338–2349.
https://doi.org/10.1158/1078-0432.CCR-13-3157
Published: 30 April 2014
View article titled, Prevalence and Clinical Implications of Epstein–Barr Virus Infection in <em>De Novo</em> Diffuse Large B-Cell Lymphoma in Western Countries
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Includes: Supplementary data
Journal Articles

Expression of p21 Protein Predicts Clinical Outcome in DLBCL Patients Older than 60 Years Treated with R-CHOP but not CHOP: A Prospective ECOG and Southwest Oncology Group Correlative Study on E4494

Jane N. Winter, Shuli Li, Vikas Aurora, Daina Variakojis, Beverly Nelson, Maryla Krajewska, Lijun Zhang, Thomas M. Habermann, Richard I. Fisher, William R. Macon, Mukesh Chhanabhai, Raymond E. Felgar, Eric D. Hsi, L. Jeffrey Medeiros, James K. Weick, Edie A. Weller, Ari Melnick, John C. Reed, Sandra J. Horning, Randy D. Gascoyne
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (8): 2435–2442.
https://doi.org/10.1158/1078-0432.CCR-09-1219
Published: 14 April 2010
View article titled, Expression of p21 Protein Predicts Clinical Outcome in DLBCL Patients Older than 60 Years Treated with R-CHOP but not CHOP: A Prospective ECOG and Southwest Oncology Group Correlative Study on E4494
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Includes: Supplementary data
Journal Articles

Inhibition of p53-Murine Double Minute 2 Interaction by Nutlin-3A Stabilizes p53 and Induces Cell Cycle Arrest and Apoptosis in Hodgkin Lymphoma

Elias Drakos, Athanasios Thomaides, L. Jeffrey Medeiros, Jiang Li, Vasiliki Leventaki, Marina Konopleva, Michael Andreeff, George Z. Rassidakis
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (11): 3380–3387.
https://doi.org/10.1158/1078-0432.CCR-06-2581
Published: 01 June 2007
View article titled, Inhibition of p53-Murine Double Minute 2 Interaction by Nutlin-3A Stabilizes p53 and Induces Cell Cycle Arrest and Apoptosis in Hodgkin Lymphoma
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Journal Articles

Inhibition of Heat Shock Protein 90 Function by 17-Allylamino-17-Demethoxy-Geldanamycin in Hodgkin's Lymphoma Cells Down-Regulates Akt Kinase, Dephosphorylates Extracellular Signal–Regulated Kinase, and Induces Cell Cycle Arrest and Cell Death

Georgios V. Georgakis, Yang Li, Georgios Z. Rassidakis, Hector Martinez-Valdez, L. Jeffrey Medeiros, Anas Younes
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (2): 584–590.
https://doi.org/10.1158/1078-0432.CCR-05-1194
Published: 20 January 2006
View article titled, Inhibition of Heat Shock Protein 90 Function by 17-Allylamino-17-Demethoxy-Geldanamycin in Hodgkin's Lymphoma Cells Down-Regulates Akt Kinase, Dephosphorylates Extracellular Signal–Regulated Kinase, and Induces Cell Cycle Arrest and Cell Death
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Journal Articles

Degree of CD25 Expression in T-Cell Lymphoma Is Dependent on Tissue Site: Implications for Targeted Therapy

Dan Jones, Sherif Ibrahim, Kaushali Patel, Rajyalakshmi Luthra, Madeleine Duvic, L. Jeffrey Medeiros
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (16): 5587–5594.
https://doi.org/10.1158/1078-0432.CCR-0721-03
Published: 24 August 2004
View article titled, Degree of CD25 Expression in T-Cell Lymphoma Is Dependent on Tissue Site: <subtitle>Implications for Targeted Therapy</subtitle>
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Journal Articles

Differential Expression and Clinical Significance of Tyrosine-phosphorylated STAT3 in ALK + and ALK − Anaplastic Large Cell Lymphoma

Joseph D. Khoury, L. Jeffrey Medeiros, George Z. Rassidakis, Marwan A. Yared, Panagiota Tsioli, Vasiliki Leventaki, Annette Schmitt-Graeff, Marco Herling, Hesham M. Amin, Raymond Lai
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (10): 3692–3699.
Published: 23 September 2003
View article titled, Differential Expression and Clinical Significance of Tyrosine-phosphorylated STAT3 in <em>ALK</em> <sup> <em>+</em> </sup> and <em>ALK</em> <sup> <em>−</em> </sup> Anaplastic Large Cell Lymphoma
Open the PDF for Differential Expression and Clinical Significance of Tyrosine-phosphorylated STAT3 in <em>ALK</em> <sup> <em>+</em> </sup> and <em>ALK</em> <sup> <em>−</em> </sup> Anaplastic Large Cell Lymphoma in another window
Journal Articles

Prognostic Significance of MUC-1 Expression in Systemic Anaplastic Large Cell Lymphoma

George Z. Rassidakis, Andre Goy, L. Jeffrey Medeiros, Yunfang Jiang, Athanasios Thomaides, Yvonne Remache, Fernando Cabanillas, Andreas H. Sarris, Frederic Gilles
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (6): 2213–2220.
Published: 01 June 2003
View article titled, Prognostic Significance of MUC-1 Expression in Systemic Anaplastic Large Cell Lymphoma
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Journal Articles

Expression of Epstein-Barr Virus Latent Membrane Protein-1 in Hodgkin and Reed-Sternberg Cells of Classical Hodgkin’s Lymphoma: Associations with Presenting Features, Serum Interleukin 10 Levels, and Clinical Outcome

Marco Herling, George Z. Rassidakis, L. Jeffrey Medeiros, Theodoros P. Vassilakopoulos, Kay-Oliver Kliche, Gianpaolo Nadali, Simonetta Viviani, Valeria Bonfante, Roberto Giardini, Marco Chilosi, Christos Kittas, Alessandro M. Gianni, Gianni Bonadonna, Giovanni Pizzolo, Gerassimos A. Pangalis, Fernando Cabanillas, Andreas H. Sarris
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (6): 2114–2120.
Published: 01 June 2003
View article titled, Expression of Epstein-Barr Virus Latent Membrane Protein-1 in Hodgkin and Reed-Sternberg Cells of Classical Hodgkin’s Lymphoma: <subtitle>Associations with Presenting Features, Serum Interleukin 10 Levels, and Clinical Outcome</subtitle>
Open the PDF for Expression of Epstein-Barr Virus Latent Membrane Protein-1 in Hodgkin and Reed-Sternberg Cells of Classical Hodgkin’s Lymphoma: <subtitle>Associations with Presenting Features, Serum Interleukin 10 Levels, and Clinical Outcome</subtitle> in another window
Journal Articles

Expression of p27Kip1 and c-Jun Activation Binding Protein 1 Are Inversely Correlated in Systemic Anaplastic Large Cell Lymphoma

George Z. Rassidakis, Francois-Xavier Claret, Raymond Lai, Qingxiu Zhang, Andreas H. Sarris, Timothy J. McDonnell, L. Jeffrey Medeiros
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (3): 1121–1128.
Published: 01 March 2003
View article titled, Expression of p27<sup>Kip1</sup> and c-Jun Activation Binding Protein 1 Are Inversely Correlated in Systemic Anaplastic Large Cell Lymphoma
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Journal Articles

BAX Expression in Hodgkin and Reed-Sternberg Cells of Hodgkin’s Disease: Correlation with Clinical Outcome

George Z. Rassidakis, L. Jeffrey Medeiros, Timothy J. McDonnell, Simonetta Viviani, Valeria Bonfante, Gianpaolo Nadali, Theodoros P. Vassilakopoulos, Roberto Giardini, Marco Chilosi, Christos Kittas, Alessandro M. Gianni, Gianni Bonadonna, Giovanni Pizzolo, Gerassimos A. Pangalis, Fernando Cabanillas, Andreas H. Sarris
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (2): 488–493.
Published: 01 February 2002
View article titled, BAX Expression in Hodgkin and Reed-Sternberg Cells of Hodgkin’s Disease: <subtitle>Correlation with Clinical Outcome</subtitle>
Open the PDF for BAX Expression in Hodgkin and Reed-Sternberg Cells of Hodgkin’s Disease: <subtitle>Correlation with Clinical Outcome</subtitle> in another window