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Kristen Hege
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Journal Articles

DNA-Dependent Protein Kinase Drives Prostate Cancer Progression through Transcriptional Regulation of the Wnt Signaling Pathway

Vishal Kothari, Jonathan F. Goodwin, Shuang G. Zhao, Justin M. Drake, Yi Yin, S. Laura Chang, Joseph R. Evans, Kari Wilder-Romans, Kristina Gabbara, Emanuela Dylgjeri, Jonathan Chou, Grace Sun, Scott A. Tomlins, Rohit Mehra, Kristen Hege, Ellen H. Filvaroff, Edward M. Schaeffer, R. Jeffrey Karnes, David A. Quigley, Dana E. Rathkopf, Housheng H. He, Corey Speers, Daniel E. Spratt, Luke A. Gilbert, Alan Ashworth, Arul M. Chinnaiyan, Ganesh V. Raj, Karen E. Knudsen, Felix Y. Feng
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (18): 5608–5622.
https://doi.org/10.1158/1078-0432.CCR-18-2387
Published: 13 September 2019
View article titled, DNA-Dependent Protein Kinase Drives Prostate Cancer Progression through Transcriptional Regulation of the Wnt Signaling Pathway
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Journal Articles

A First-in-Human Study of Novel Cereblon Modulator Avadomide (CC-122) in Advanced Malignancies

Drew W. Rasco, Kyriakos P. Papadopoulos, Michael Pourdehnad, Anita K. Gandhi, Patrick R. Hagner, Yan Li, Xin Wei, Rajesh Chopra, Kristen Hege, Jorge DiMartino, Kent Shih
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (1): 90–98.
https://doi.org/10.1158/1078-0432.CCR-18-1203
Published: 03 January 2019
View article titled, A First-in-Human Study of Novel Cereblon Modulator Avadomide (CC-122) in Advanced Malignancies
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Includes: Supplementary data
Journal Articles

Abstract B20: Immune vs. clinical response monitoring in patients with metastatic hormone-refractory prostate cancer receiving combined prostate GVAX and anti-CTLA4 immunotherapy

Saskia J.A.M. Santegoets, Alfons J.M. van den Eertwegh, Anita G.M. Stam, Rik J. Scheper, Sinead M. Lougheed, Petra E.T. Scholten, Helen Gall, Karin Jooss, Natalie Sacks, Thomas C. Harding, Kristen Hege, Israel Lowy, Winald R. Gerritsen, Tanja D. de Gruijl
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (7_Supplement): B20.
https://doi.org/10.1158/1078-0432.TCME10-B20
Published: 02 February 2016
View article titled, Abstract B20: Immune vs. clinical response monitoring in patients with metastatic hormone-refractory prostate cancer receiving combined prostate GVAX and anti-CTLA4 immunotherapy
Journal Articles

The mTOR Kinase Inhibitors, CC214-1 and CC214-2, Preferentially Block the Growth of EGFRvIII-Activated Glioblastomas

Beatrice Gini, Ciro Zanca, Deliang Guo, Tomoo Matsutani, Kenta Masui, Shiro Ikegami, Huijun Yang, David Nathanson, Genaro R. Villa, David Shackelford, Shaojun Zhu, Kazuhiro Tanaka, Ivan Babic, David Akhavan, Kelly Lin, Alvaro Assuncao, Yuchao Gu, Bruno Bonetti, Deborah S. Mortensen, Shuichan Xu, Heather K. Raymon, Webster K. Cavenee, Frank B. Furnari, C. David James, Guido Kroemer, James R. Heath, Kristen Hege, Rajesh Chopra, Timothy F. Cloughesy, Paul S. Mischel
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (20): 5722–5732.
https://doi.org/10.1158/1078-0432.CCR-13-0527
Published: 14 October 2013
View article titled, The mTOR Kinase Inhibitors, CC214-1 and CC214-2, Preferentially Block the Growth of EGFRvIII-Activated Glioblastomas
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Includes: Supplementary data
Journal Articles

K562/GM-CSF Immunotherapy Reduces Tumor Burden in Chronic Myeloid Leukemia Patients with Residual Disease on Imatinib Mesylate

B. Douglas Smith, Yvette L. Kasamon, Jeanne Kowalski, Christopher Gocke, Kathleen Murphy, Carole B. Miller, Elizabeth Garrett-Mayer, Hua-Ling Tsai, Lu Qin, Christina Chia, Barbara Biedrzycki, Thomas C. Harding, Guang Haun Tu, Richard Jones, Kristen Hege, Hyam I. Levitsky
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (1): 338–347.
https://doi.org/10.1158/1078-0432.CCR-09-2046
Published: 04 January 2010
View article titled, K562/GM-CSF Immunotherapy Reduces Tumor Burden in Chronic Myeloid Leukemia Patients with Residual Disease on Imatinib Mesylate
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Includes: Supplementary data
Journal Articles

Allogeneic Granulocyte Macrophage Colony-Stimulating Factor–Secreting Tumor Immunotherapy Alone or in Sequence with Cyclophosphamide for Metastatic Pancreatic Cancer: A Pilot Study of Safety, Feasibility, and Immune Activation

Dan Laheru, Eric Lutz, James Burke, Barbara Biedrzycki, Sara Solt, Beth Onners, Irena Tartakovsky, John Nemunaitis, Dung Le, Elizabeth Sugar, Kristen Hege, Elizabeth Jaffee
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (5): 1455–1463.
https://doi.org/10.1158/1078-0432.CCR-07-0371
Published: 03 March 2008
View article titled, Allogeneic Granulocyte Macrophage Colony-Stimulating Factor–Secreting Tumor Immunotherapy Alone or in Sequence with Cyclophosphamide for Metastatic Pancreatic Cancer: A Pilot Study of Safety, Feasibility, and Immune Activation
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Includes: Supplementary data
Journal Articles

Granulocyte Macrophage Colony-Stimulating Factor–Secreting Allogeneic Cellular Immunotherapy for Hormone-Refractory Prostate Cancer

Eric J. Small, Natalie Sacks, John Nemunaitis, Walter J. Urba, Eugene Dula, Arthur S. Centeno, William G. Nelson, Dale Ando, Catherine Howard, Flavia Borellini, Minh Nguyen, Kristen Hege, Jonathan W. Simons
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (13): 3883–3891.
https://doi.org/10.1158/1078-0432.CCR-06-2937
Published: 02 July 2007
View article titled, Granulocyte Macrophage Colony-Stimulating Factor–Secreting Allogeneic Cellular Immunotherapy for Hormone-Refractory Prostate Cancer
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