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Journal Articles

Plasma Protein Biomarkers in Advanced or Metastatic Colorectal Cancer Patients Receiving Chemotherapy With Bevacizumab or Cetuximab: Results from CALGB 80405 (Alliance)

Andrew B. Nixon, Alexander B. Sibley, Yingmiao Liu, Ace J. Hatch, Chen Jiang, Flora Mulkey, Mark D. Starr, John C. Brady, Donna Niedzwiecki, Alan P. Venook, Luis Baez-Diaz, Heinz-Josef Lenz, Bert H. O'Neil, Federico Innocenti, Jeffrey A. Meyerhardt, Eileen M. O'Reilly, Kouros Owzar, Herbert I. Hurwitz
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (13): 2779–2788.
https://doi.org/10.1158/1078-0432.CCR-21-2389
Published: 01 July 2022
View articletitled, Plasma Protein Biomarkers in Advanced or Metastatic Colorectal Cancer Patients Receiving Chemotherapy With Bevacizumab or Cetuximab: Results from CALGB 80405 (Alliance)
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Includes: Supplementary data
Journal Articles

Clinical Trials with Biologic Primary Endpoints in Immuno-oncology: Concepts and Usage

James Isaacs, Aaron C. Tan, Brent A. Hanks, Xiaofei Wang, Kouros Owzar, James E. Herndon, II, Scott J. Antonia, Steven Piantadosi, Mustafa Khasraw
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (1): 13–22.
https://doi.org/10.1158/1078-0432.CCR-21-1593
Published: 05 January 2022
View articletitled, Clinical Trials with Biologic Primary Endpoints in Immuno-oncology: Concepts and Usage
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Journal Articles

Genomic Analysis of Germline Variation Associated with Survival of Patients with Colorectal Cancer Treated with Chemotherapy Plus Biologics in CALGB/SWOG 80405 (Alliance)

Federico Innocenti, Alexander B. Sibley, Sushant A. Patil, Amy S. Etheridge, Chen Jiang, Fang-Shu Ou, Stefanie D. Howell, Sarah J. Plummer, Graham Casey, Monica M. Bertagnolli, Howard L. McLeod, James T. Auman, Charles D. Blanke, Yoichi Furukawa, Alan P. Venook, Michiaki Kubo, Heinz-Josef Lenz, Joel S. Parker, Mark J. Ratain, Kouros Owzar
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (1): 267–275.
https://doi.org/10.1158/1078-0432.CCR-20-2021
Published: 04 January 2021
View articletitled, Genomic Analysis of Germline Variation Associated with Survival of Patients with Colorectal Cancer Treated with Chemotherapy Plus Biologics in CALGB/SWOG 80405 (Alliance)
Open the PDF for Genomic Analysis of Germline Variation Associated with Survival of Patients with Colorectal Cancer Treated with Chemotherapy Plus Biologics in CALGB/SWOG 80405 (Alliance) in another window
Includes: Supplementary data
Journal Articles

Predictive Blood-Based Biomarkers in Patients with Epithelial Ovarian Cancer Treated with Carboplatin and Paclitaxel with or without Bevacizumab: Results from GOG-0218

Angeles Alvarez Secord, Kirsten Bell Burdett, Kouros Owzar, David Tritchler, Alexander B. Sibley, Yingmiao Liu, Mark D. Starr, J. Chris Brady, Heather A. Lankes, Herbert I. Hurwitz, Robert S. Mannel, Krishnansu S. Tewari, David M. O'Malley, Heidi Gray, Jamie N. Bakkum-Gamez, Keiichi Fujiwara, Matthew Boente, Wei Deng, Robert A. Burger, Michael J. Birrer, Andrew B. Nixon
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (6): 1288–1296.
https://doi.org/10.1158/1078-0432.CCR-19-0226
Published: 13 March 2020
View articletitled, Predictive Blood-Based Biomarkers in Patients with Epithelial Ovarian Cancer Treated with Carboplatin and Paclitaxel with or without Bevacizumab: Results from GOG-0218
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Includes: Supplementary data
Journal Articles

Identification of a Genomic Region between SLC29A1 and HSP90AB1 Associated with Risk of Bevacizumab-Induced Hypertension: CALGB 80405 (Alliance)

Megan Li, Flora Mulkey, Chen Jiang, Bert H. O’Neil, Bryan P. Schneider, Fei Shen, Paula N. Friedman, Yukihide Momozawa, Michiaki Kubo, Donna Niedzwiecki, Howard S. Hochster, Heinz-Josef Lenz, James N. Atkins, Hope S. Rugo, Susan Halabi, William Kevin Kelly, Howard L. McLeod, Federico Innocenti, Mark J. Ratain, Alan P. Venook, Kouros Owzar, Deanna L. Kroetz
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (19): 4734–4744.
https://doi.org/10.1158/1078-0432.CCR-17-1523
Published: 01 October 2018
View articletitled, Identification of a Genomic Region between SLC29A1 and HSP90AB1 Associated with Risk of Bevacizumab-Induced Hypertension: CALGB 80405 (Alliance)
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Includes: Supplementary data
Journal Articles

Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy

Daniel L. Hertz, Kouros Owzar, Sherrie Lessans, Claudia Wing, Chen Jiang, William Kevin Kelly, Jai Patel, Susan Halabi, Yoichi Furukawa, Heather E. Wheeler, Alexander B. Sibley, Cameron Lassiter, Lois Weisman, Dorothy Watson, Stefanie D. Krens, Flora Mulkey, Cynthia L. Renn, Eric J. Small, Phillip G. Febbo, Ivo Shterev, Deanna L. Kroetz, Paula N. Friedman, John F. Mahoney, Michael A. Carducci, Michael J. Kelley, Yusuke Nakamura, Michiaki Kubo, Susan G. Dorsey, M. Eileen Dolan, Michael J. Morris, Mark J. Ratain, Howard L. McLeod
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (19): 4890–4900.
https://doi.org/10.1158/1078-0432.CCR-15-2823
Published: 02 October 2016
View articletitled, Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy
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Includes: Supplementary data
Journal Articles

Gene Expression Markers of Efficacy and Resistance to Cetuximab Treatment in Metastatic Colorectal Cancer: Results from CALGB 80203 (Alliance)

Stephanie M. Cushman, Chen Jiang, Ace J. Hatch, Ivo Shterev, Alexander B. Sibley, Donna Niedzwiecki, Alan P. Venook, Kouros Owzar, Herbert I. Hurwitz, Andrew B. Nixon
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (5): 1078–1086.
https://doi.org/10.1158/1078-0432.CCR-14-2313
Published: 01 March 2015
View articletitled, Gene Expression Markers of Efficacy and Resistance to Cetuximab Treatment in Metastatic Colorectal Cancer: Results from CALGB 80203 (Alliance)
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Includes: Supplementary data
Journal Articles

Integration of Cell Line and Clinical Trial Genome-Wide Analyses Supports a Polygenic Architecture of Paclitaxel-Induced Sensory Peripheral Neuropathy

Heather E. Wheeler, Eric R. Gamazon, Claudia Wing, Uchenna O. Njiaju, Chidiamara Njoku, Robert Michael Baldwin, Kouros Owzar, Chen Jiang, Dorothy Watson, Ivo Shterev, Michiaki Kubo, Hitoshi Zembutsu, Eric P. Winer, Clifford A. Hudis, Lawrence N. Shulman, Yusuke Nakamura, Mark J. Ratain, Deanna L. Kroetz, Nancy J. Cox, Mary Eileen Dolan
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (2): 491–499.
https://doi.org/10.1158/1078-0432.CCR-12-2618
Published: 16 January 2013
View articletitled, Integration of Cell Line and Clinical Trial Genome-Wide Analyses Supports a Polygenic Architecture of Paclitaxel-Induced Sensory Peripheral Neuropathy
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Includes: Supplementary data
Journal Articles

A Genome-Wide Association Study Identifies Novel Loci for Paclitaxel-Induced Sensory Peripheral Neuropathy in CALGB 40101

R. Michael Baldwin, Kouros Owzar, Hitoshi Zembutsu, Aparna Chhibber, Michiaki Kubo, Chen Jiang, Dorothy Watson, Rachel J. Eclov, Joel Mefford, Howard L. McLeod, Paula N. Friedman, Clifford A. Hudis, Eric P. Winer, Eric M. Jorgenson, John S. Witte, Lawrence N. Shulman, Yusuke Nakamura, Mark J. Ratain, Deanna L. Kroetz
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (18): 5099–5109.
https://doi.org/10.1158/1078-0432.CCR-12-1590
Published: 16 September 2012
View articletitled, A Genome-Wide Association Study Identifies Novel Loci for Paclitaxel-Induced Sensory Peripheral Neuropathy in CALGB 40101
Open the PDF for A Genome-Wide Association Study Identifies Novel Loci for Paclitaxel-Induced Sensory Peripheral Neuropathy in CALGB 40101 in another window
Includes: Supplementary data
Journal Articles

A Genome-Wide Association Study of Overall Survival in Pancreatic Cancer Patients Treated with Gemcitabine in CALGB 80303

Federico Innocenti, Kouros Owzar, Nancy L. Cox, Patrick Evans, Michiaki Kubo, Hitoshi Zembutsu, Chen Jiang, Donna Hollis, Taisei Mushiroda, Liang Li, Paula Friedman, Liewei Wang, Dylan Glubb, Herbert Hurwitz, Kathleen M. Giacomini, Howard L. McLeod, Richard M. Goldberg, Richard L. Schilsky, Hedy L. Kindler, Yusuke Nakamura, Mark J. Ratain
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (2): 577–584.
https://doi.org/10.1158/1078-0432.CCR-11-1387
Published: 16 January 2012
View articletitled, A Genome-Wide Association Study of Overall Survival in Pancreatic Cancer Patients Treated with Gemcitabine in CALGB 80303
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Includes: Supplementary data
Journal Articles

Statistical Challenges in Preprocessing in Microarray Experiments in Cancer

Kouros Owzar, William T. Barry, Sin-Ho Jung, Insuk Sohn, Stephen L. George
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (19): 5959–5966.
https://doi.org/10.1158/1078-0432.CCR-07-4532
Published: 30 September 2008
View articletitled, Statistical Challenges in Preprocessing in Microarray Experiments in Cancer
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