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Konstantinos N. Syrigos
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Journal Articles

Alpha-smooth Muscle Actin Expression in the Stroma Predicts Resistance to Trastuzumab in Patients with Early-stage HER2-positive Breast Cancer

Ioannis A. Vathiotis, Myrto K. Moutafi, Prajan Divakar, Thazin Nwe Aung, Tao Qing, Aileen Fernandez, Vesal Yaghoobi, Sarra El-Abed, Yingbo Wang, Sebastien Guillaume, Paolo Nuciforo, Jens Huober, Serena Di Cosimo, Sung-Bae Kim, Nadia Harbeck, Henry Gomez, Saba Shafi, Konstantinos N. Syrigos, George Fountzilas, Christos Sotiriou, Lajos Pusztai, Sarah Warren, David L. Rimm
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (22): 6156–6163.
https://doi.org/10.1158/1078-0432.CCR-21-2103
Published: 15 November 2021
View article titled, Alpha-smooth Muscle Actin Expression in the Stroma Predicts Resistance to Trastuzumab in Patients with Early-stage HER2-positive Breast Cancer
Open the PDF for Alpha-smooth Muscle Actin Expression in the Stroma Predicts Resistance to Trastuzumab in Patients with Early-stage HER2-positive Breast Cancer in another window
Includes: Supplementary data
Journal Articles

High-Plex Predictive Marker Discovery for Melanoma Immunotherapy–Treated Patients Using Digital Spatial Profiling

Maria I. Toki, Christopher R. Merritt, Pok Fai Wong, James W. Smithy, Harriet M. Kluger, Konstantinos N. Syrigos, Giang T. Ong, Sarah E. Warren, Joseph M. Beechem, David L. Rimm
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (18): 5503–5512.
https://doi.org/10.1158/1078-0432.CCR-19-0104
Published: 13 September 2019
View article titled, High-Plex Predictive Marker Discovery for Melanoma Immunotherapy–Treated Patients Using Digital Spatial Profiling
Open the PDF for High-Plex Predictive Marker Discovery for Melanoma Immunotherapy–Treated Patients Using Digital Spatial Profiling in another window
Includes: Supplementary data
Journal Articles

Phase I/II Trial of Carboplatin and Paclitaxel Chemotherapy in Combination with Intravenous Oncolytic Reovirus in Patients with Advanced Malignancies

Eleni M. Karapanagiotou, Victoria Roulstone, Katie Twigger, Mercel Ball, MaryAnne Tanay, Chris Nutting, Kate Newbold, Martin E. Gore, James Larkin, Konstantinos N. Syrigos, Matt Coffey, Brad Thompson, Karl Mettinger, Richard G. Vile, Hardev S. Pandha, Geoff D. Hall, Alan A. Melcher, John Chester, Kevin J. Harrington
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (7): 2080–2089.
https://doi.org/10.1158/1078-0432.CCR-11-2181
Published: 01 April 2012
View article titled, Phase I/II Trial of Carboplatin and Paclitaxel Chemotherapy in Combination with Intravenous Oncolytic Reovirus in Patients with Advanced Malignancies
Open the PDF for Phase I/II Trial of Carboplatin and Paclitaxel Chemotherapy in Combination with Intravenous Oncolytic Reovirus in Patients with Advanced Malignancies in another window
Includes: Supplementary data
Journal Articles

High Expression of Mammalian Target of Rapamycin Is Associated with Better Outcome for Patients with Early Stage Lung Adenocarcinoma

Valsamo K. Anagnostou, Gerold Bepler, Konstantinos N. Syrigos, Lynn Tanoue, Scott Gettinger, Robert J. Homer, Daniel Boffa, Frank Detterbeck, David L. Rimm
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (12): 4157–4164.
https://doi.org/10.1158/1078-0432.CCR-09-0099
Published: 15 June 2009
View article titled, High Expression of Mammalian Target of Rapamycin Is Associated with Better Outcome for Patients with Early Stage Lung Adenocarcinoma
Open the PDF for High Expression of Mammalian Target of Rapamycin Is Associated with Better Outcome for Patients with Early Stage Lung Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Pegylated Liposome-encapsulated Doxorubicin and Cisplatin Enhance the Effect of Radiotherapy in a Tumor Xenograft Model

Kevin J. Harrington, Gail Rowlinson-Busza, Konstantinos N. Syrigos, Richard G. Vile, Paul S. Uster, A. Michael Peters, J. Simon W. Stewart
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (12): 4939–4949.
Published: 01 December 2000
View article titled, Pegylated Liposome-encapsulated Doxorubicin and Cisplatin Enhance the Effect of Radiotherapy in a Tumor Xenograft Model
Open the PDF for Pegylated Liposome-encapsulated Doxorubicin and Cisplatin Enhance the Effect of Radiotherapy in a Tumor Xenograft Model in another window
Journal Articles

Pegylated Liposomes Have Potential as Vehicles for Intratumoral and Subcutaneous Drug Delivery

Kevin J. Harrington, Gail Rowlinson-Busza, Konstantinos N. Syrigos, Paul S. Uster, Richard G. Vile, J. Simon W. Stewart
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (6): 2528–2537.
Published: 01 June 2000
View article titled, Pegylated Liposomes Have Potential as Vehicles for Intratumoral and Subcutaneous Drug Delivery
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