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Klaus-Michael Debatin
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Journal Articles

LDHA in Neuroblastoma Is Associated with Poor Outcome and Its Depletion Decreases Neuroblastoma Growth Independent of Aerobic Glycolysis

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Carmen Dorneburg, Matthias Fischer, Thomas F.E. Barth, Wolfgang Mueller-Klieser, Barbara Hero, Judith Gecht, Daniel R. Carter, Katleen de Preter, Benjamin Mayer, Lisa Christner, Frank Speleman, Glenn M. Marshall, Klaus-Michael Debatin, Christian Beltinger
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (22): 5772–5783.
https://doi.org/10.1158/1078-0432.CCR-17-2578
Published: 15 November 2018
View articletitled, LDHA in Neuroblastoma Is Associated with Poor Outcome and Its Depletion Decreases Neuroblastoma Growth Independent of Aerobic Glycolysis
Open the PDF for LDHA in Neuroblastoma Is Associated with Poor Outcome and Its Depletion Decreases Neuroblastoma Growth Independent of Aerobic Glycolysis in another window
Includes: Supplementary data
Journal Articles

Prospective Validation of a New Method of Monitoring Minimal Residual Disease in Childhood Acute Myelogenous Leukemia

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Daniel Steinbach, Peter Bader, Andre Willasch, Stephan Bartholomae, Klaus-Michael Debatin, Martin Zimmermann, Ursula Creutzig, Dirk Reinhardt, Bernd Gruhn
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (6): 1353–1359.
https://doi.org/10.1158/1078-0432.CCR-14-1999
Published: 12 March 2015
View articletitled, Prospective Validation of a New Method of Monitoring Minimal Residual Disease in Childhood Acute Myelogenous Leukemia
Open the PDF for Prospective Validation of a New Method of Monitoring Minimal Residual Disease in Childhood Acute Myelogenous Leukemia in another window
Journal Articles

Bortezomib Primes Glioblastoma, Including Glioblastoma Stem Cells, for TRAIL by Increasing tBid Stability and Mitochondrial Apoptosis

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Thomas Unterkircher, Silvia Cristofanon, Sri Hari Krishna Vellanki, Lisa Nonnenmacher, Georg Karpel-Massler, Christian Rainer Wirtz, Klaus-Michael Debatin, Simone Fulda
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (12): 4019–4030.
https://doi.org/10.1158/1078-0432.CCR-11-0075
Published: 15 June 2011
View articletitled, Bortezomib Primes Glioblastoma, Including Glioblastoma Stem Cells, for TRAIL by Increasing tBid Stability and Mitochondrial Apoptosis
Open the PDF for Bortezomib Primes Glioblastoma, Including Glioblastoma Stem Cells, for TRAIL by Increasing tBid Stability and Mitochondrial Apoptosis in another window
Journal Articles

Targeting Aberrant PI3K/Akt Activation by PI103 Restores Sensitivity to TRAIL-Induced Apoptosis in Neuroblastoma

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Daniela Opel, Ivonne Naumann, Maxi Schneider, Daniela Bertele, Klaus-Michael Debatin, Simone Fulda
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (10): 3233–3247.
https://doi.org/10.1158/1078-0432.CCR-10-2530
Published: 15 May 2011
View articletitled, Targeting Aberrant PI3K/Akt Activation by PI103 Restores Sensitivity to TRAIL-Induced Apoptosis in Neuroblastoma
Open the PDF for Targeting Aberrant PI3K/Akt Activation by PI103 Restores Sensitivity to TRAIL-Induced Apoptosis in Neuroblastoma in another window
Includes: Supplementary data
Journal Articles

Bortezomib Primes Neuroblastoma Cells for TRAIL-Induced Apoptosis by Linking the Death Receptor to the Mitochondrial Pathway

Free
Ivonne Naumann, Roland Kappler, Dietrich von Schweinitz, Klaus-Michael Debatin, Simone Fulda
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (10): 3204–3218.
https://doi.org/10.1158/1078-0432.CCR-10-2451
Published: 15 May 2011
View articletitled, Bortezomib Primes Neuroblastoma Cells for TRAIL-Induced Apoptosis by Linking the Death Receptor to the Mitochondrial Pathway
Open the PDF for Bortezomib Primes Neuroblastoma Cells for TRAIL-Induced Apoptosis by Linking the Death Receptor to the Mitochondrial Pathway in another window
Includes: Supplementary data
Journal Articles

TRAIL-Induced Apoptosis Is Preferentially Mediated via TRAIL Receptor 1 in Pancreatic Carcinoma Cells and Profoundly Enhanced by XIAP Inhibitors

Free
Dominic Stadel, Andrea Mohr, Caroline Ref, Marion MacFarlane, Shaoxia Zhou, Robin Humphreys, Max Bachem, Gerry Cohen, Peter Möller, Ralf M. Zwacka, Klaus-Michael Debatin, Simone Fulda
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (23): 5734–5749.
https://doi.org/10.1158/1078-0432.CCR-10-0985
Published: 06 December 2010
View articletitled, TRAIL-Induced Apoptosis Is Preferentially Mediated via TRAIL Receptor 1 in Pancreatic Carcinoma Cells and Profoundly Enhanced by XIAP Inhibitors
Open the PDF for TRAIL-Induced Apoptosis Is Preferentially Mediated via TRAIL Receptor 1 in Pancreatic Carcinoma Cells and Profoundly Enhanced by XIAP Inhibitors in another window
Includes: Supplementary data