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Kimberly Stegmaier
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Journal Articles

Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma

Jonathan Paolino, Boris Dimitrov, Beth Apsel Winger, Angelica Sandoval-Perez, Amith Vikram Rangarajan, Nicole Ocasio-Martinez, Harrison K. Tsai, Yuting Li, Amanda L. Robichaud, Delan Khalid, Charlie Hatton, Riaz Gillani, Petri Polonen, Anthony Dilig, Giacomo Gotti, Julia Kavanagh, Asmani A. Adhav, Sean Gow, Jonathan Tsai, Yen Der Li, Benjamin L. Ebert, Eliezer M. Van Allen, Jacob Bledsoe, Annette S. Kim, Sarah K. Tasian, Stacy L. Cooper, Todd M. Cooper, Nobuko Hijiya, Maria Luisa Sulis, Neerav N. Shukla, Jeffrey A. Magee, Charles G. Mullighan, Michael J. Burke, Marlise R. Luskin, Brenton G. Mar, Matthew P. Jacobson, Marian H. Harris, Kimberly Stegmaier, Andrew E. Place, Yana Pikman
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (22): 4613–4626.
https://doi.org/10.1158/1078-0432.CCR-22-2562
Published: 14 November 2023
View article titled, Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Open the PDF for Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma in another window
Includes: Supplementary data
Journal Articles

Abstract B021: Long non-coding RNAs that are required for robust cell growth in ewing Sarcoma

Marcela C. Briones Martin del Campo, Alex Lee, Max Horlbeck, Truc Dinh, Marta Roman-Moreno, Leanne Sayles, Bokyung Seong, Kimberly Stegmaier, Luke Gilbert, E. Alejandro Sweet-Cordero
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (18_Supplement): B021.
https://doi.org/10.1158/1557-3265.SARCOMAS22-B021
Published: 15 September 2022
View article titled, Abstract B021: Long non-coding RNAs that are required for robust cell growth in ewing Sarcoma
Journal Articles

High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma

Sarah Wang, Elizabeth E. Hwang, Rajarshi Guha, Allison F. O'Neill, Nicole Melong, Chansey J. Veinotte, Amy Conway Saur, Kellsey Wuerthele, Min Shen, Crystal McKnight, Gabriela Alexe, Madeleine E. Lemieux, Amy Wang, Emma Hughes, Xin Xu, Matthew B. Boxer, Matthew D. Hall, Andrew Kung, Jason N. Berman, Mindy I. Davis, Kimberly Stegmaier, Brian D. Crompton
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (14): 4552–4566.
https://doi.org/10.1158/1078-0432.CCR-17-0375
Published: 15 July 2019
View article titled, High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma
Open the PDF for High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma in another window
Includes: Supplementary data
Journal Articles

A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing Sarcoma

Lillian M. Guenther, Neekesh V. Dharia, Linda Ross, Amy Conway, Amanda L. Robichaud, Jerrel L. Catlett, II, Caroline S. Wechsler, Elizabeth S. Frank, Amy Goodale, Alanna J. Church, Yuen-Yi Tseng, Rajarshi Guha, Crystal G. McKnight, Katherine A. Janeway, Jesse S. Boehm, Jaume Mora, Mindy I. Davis, Gabriela Alexe, Federica Piccioni, Kimberly Stegmaier
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (4): 1343–1357.
https://doi.org/10.1158/1078-0432.CCR-18-0372
Published: 15 February 2019
View article titled, A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing Sarcoma
Open the PDF for A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing Sarcoma in another window
Includes: Supplementary data
Journal Articles

Synergistic Drug Combinations with a CDK4/6 Inhibitor in T-cell Acute Lymphoblastic Leukemia

Yana Pikman, Gabriela Alexe, Giovanni Roti, Amy Saur Conway, Andrew Furman, Emily S. Lee, Andrew E. Place, Sunkyu Kim, Chitra Saran, Rebecca Modiste, David M. Weinstock, Marian Harris, Andrew L. Kung, Lewis B. Silverman, Kimberly Stegmaier
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (4): 1012–1024.
https://doi.org/10.1158/1078-0432.CCR-15-2869
Published: 14 February 2017
View article titled, Synergistic Drug Combinations with a CDK4/6 Inhibitor in T-cell Acute Lymphoblastic Leukemia
Open the PDF for Synergistic Drug Combinations with a CDK4/6 Inhibitor in T-cell Acute Lymphoblastic Leukemia in another window
Includes: Supplementary data
Journal Articles

Abstract B39: Genomic copy number alterations introduce a gene-independent viability bias in CRISPR-Cas9 knock-out screens of cancer cell lines

Robin M. Meyers, Andrew J. Aguirre, Barbara A. Weir, Francisca Vazquez, Cheng-Zhong Zhang, Uri Ben-David, April Cook, Gavin Ha, William F. Harrington, Mihir Doshi, Stanley Gill, Han Xu, Levi D. Ali, Guozhi Jiang, Sasha Pantel, Yenarae Lee, Amy Goodale, Andrew D. Cherniack, Coyin Oh, Gregory Kryukov, Glenn S. Cowley, Levi A. Garraway, Kimberly Stegmaier, Charles W. Roberts, Todd R. Golub, Matthew Meyerson, David E. Root, Aviad Tsherniak, William C. Hahn
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (1_Supplement): B39.
https://doi.org/10.1158/1557-3265.PMCCAVULN16-B39
Published: 02 January 2017
View article titled, Abstract B39: Genomic copy number alterations introduce a gene-independent viability bias in CRISPR-Cas9 knock-out screens of cancer cell lines
Journal Articles

Abstract IA6-2: Genomic approaches to drug discovery

Kimberly Stegmaier
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (14_Supplement): IA6-2.
https://doi.org/10.1158/1078-0432.TCMUSA10-IA6-2
Published: 02 February 2016
View article titled, Abstract IA6-2: Genomic approaches to drug discovery
Journal Articles

Abstract IA23: Integrating chemical and functional genomics for leukemia discovery.

Kimberly Stegmaier
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (17_Supplement): IA23.
https://doi.org/10.1158/1557-3265.HEMMAL14-IA23
Published: 19 August 2015
View article titled, Abstract IA23: Integrating chemical and functional genomics for leukemia discovery.