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Kimberly S. Smythe
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Journal Articles

Characterization of Immunosuppressive Myeloid Cells in Merkel Cell Carcinoma: Correlation with Resistance to PD-1 Pathway Blockade

Shira Tabachnick-Cherny, Thomas Pulliam, Haroldo J. Rodriguez, Xinyi Fan, Daniel S. Hippe, Daniel C. Jones, Ata S. Moshiri, Kimberly S. Smythe, Rima M. Kulikauskas, Lisa C. Zaba, Kelly G. Paulson, Paul Nghiem
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (6): 1189–1199.
https://doi.org/10.1158/1078-0432.CCR-23-1957
Published: 15 March 2024
View article titled, Characterization of Immunosuppressive Myeloid Cells in Merkel Cell Carcinoma: Correlation with Resistance to PD-1 Pathway Blockade
Open the PDF for Characterization of Immunosuppressive Myeloid Cells in Merkel Cell Carcinoma: Correlation with Resistance to PD-1 Pathway Blockade in another window
Includes: Supplementary data
Journal Articles

A Phase 1/2 Trial Combining Avelumab and Trabectedin for Advanced Liposarcoma and Leiomyosarcoma

Michael J. Wagner, Yuzheng Zhang, Lee D. Cranmer, Elizabeth T. Loggers, Graeme Black, Sabrina McDonnell, Shannon Maxwell, Rylee Johnson, Roxanne Moore, Pedro Hermida de Viveiros, Lauri Aicher, Kimberly S. Smythe, Qianchuan He, Robin L. Jones, Seth M. Pollack
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (11): 2306–2312.
https://doi.org/10.1158/1078-0432.CCR-22-0240
Published: 01 June 2022
View article titled, A Phase 1/2 Trial Combining Avelumab and Trabectedin for Advanced Liposarcoma and Leiomyosarcoma
Open the PDF for A Phase 1/2 Trial Combining Avelumab and Trabectedin for Advanced Liposarcoma and Leiomyosarcoma in another window
Includes: Supplementary data
Journal Articles

Neoadjuvant Therapy Induces a Potent Immune Response to Sarcoma, Dominated by Myeloid and B Cells

Peter H. Goff, Laura Riolobos, Bonnie J. LaFleur, Matthew B. Spraker, Y. David Seo, Kimberly S. Smythe, Jean S. Campbell, Robert H. Pierce, Yuzheng Zhang, Qianchuan He, Edward Y. Kim, Stephanie K. Schaub, Gabrielle M. Kane, Jose G. Mantilla, Eleanor Y. Chen, Robert Ricciotti, Matthew J. Thompson, Lee D. Cranmer, Michael J. Wagner, Elizabeth T. Loggers, Robin L. Jones, Erin Murphy, Wendy M. Blumenschein, Terrill K. McClanahan, Jon Earls, Kevin C. Flanagan, Natalie A. LaFranzo, Teresa S. Kim, Seth M. Pollack
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (8): 1701–1711.
https://doi.org/10.1158/1078-0432.CCR-21-4239
Published: 14 April 2022
View article titled, Neoadjuvant Therapy Induces a Potent Immune Response to Sarcoma, Dominated by Myeloid and B Cells
Open the PDF for Neoadjuvant Therapy Induces a Potent Immune Response to Sarcoma, Dominated by Myeloid and B Cells in another window
Includes: Supplementary data
Journal Articles

Mobilization of CD8+ T Cells via CXCR4 Blockade Facilitates PD-1 Checkpoint Therapy in Human Pancreatic Cancer

Yongwoo David Seo, Xiuyun Jiang, Kevin M. Sullivan, Florencia G. Jalikis, Kimberly S. Smythe, Arezou Abbasi, Marissa Vignali, James O. Park, Sara K. Daniel, Seth M. Pollack, Teresa S. Kim, Raymond Yeung, Ian Nicholas Crispe, Robert H. Pierce, Harlan Robins, Venu G. Pillarisetty
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (13): 3934–3945.
https://doi.org/10.1158/1078-0432.CCR-19-0081
Published: 01 July 2019
View article titled, Mobilization of CD8<sup>+</sup> T Cells via CXCR4 Blockade Facilitates PD-1 Checkpoint Therapy in Human Pancreatic Cancer
Open the PDF for Mobilization of CD8<sup>+</sup> T Cells via CXCR4 Blockade Facilitates PD-1 Checkpoint Therapy in Human Pancreatic Cancer in another window
Includes: Supplementary data