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Kevin Shee
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Journal Articles

Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer

Margaret L. Axelrod, Mellissa J. Nixon, Paula I. Gonzalez-Ericsson, Riley E. Bergman, Mark A. Pilkinton, Wyatt J. McDonnell, Violeta Sanchez, Susan R. Opalenik, Sherene Loi, Jing Zhou, Sean Mackay, Brent N. Rexer, Vandana G. Abramson, Valerie M. Jansen, Simon Mallal, Joshua Donaldson, Sara M. Tolaney, Ian E. Krop, Ana C. Garrido-Castro, Jonathan D. Marotti, Kevin Shee, Todd W. Miller, Melinda E. Sanders, Ingrid A. Mayer, Roberto Salgado, Justin M. Balko
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (21): 5668–5681.
https://doi.org/10.1158/1078-0432.CCR-19-3685
Published: 02 November 2020
View articletitled, Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer
Open the PDF for Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer in another window
Includes: Supplementary data
Journal Articles

AMPK Activation by Metformin Promotes Survival of Dormant ER+ Breast Cancer Cells

Riley A. Hampsch, Jason D. Wells, Nicole A. Traphagen, Charlotte F. McCleery, Jennifer L. Fields, Kevin Shee, Lloye M. Dillon, Darcy B. Pooler, Lionel D. Lewis, Eugene Demidenko, Yina H. Huang, Jonathan D. Marotti, Abigail E. Goen, William B. Kinlaw, Todd W. Miller
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (14): 3707–3719.
https://doi.org/10.1158/1078-0432.CCR-20-0269
Published: 15 July 2020
View articletitled, AMPK Activation by Metformin Promotes Survival of Dormant ER+ Breast Cancer Cells
Open the PDF for AMPK Activation by Metformin Promotes Survival of Dormant ER+ Breast Cancer Cells in another window
Includes: Supplementary data
Journal Articles

A Transcriptionally Definable Subgroup of Triple-Negative Breast and Ovarian Cancer Samples Shows Sensitivity to HSP90 Inhibition

Kevin Shee, Jason D. Wells, Matthew Ung, Riley A. Hampsch, Nicole A. Traphagen, Wei Yang, Stephanie C. Liu, Megan A. Zeldenrust, Liewei Wang, Krishna R. Kalari, Jia Yu, Judy C. Boughey, Eugene Demidenko, Arminja N. Kettenbach, Chao Cheng, Matthew P. Goetz, Todd W. Miller
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (1): 159–170.
https://doi.org/10.1158/1078-0432.CCR-18-2213
Published: 03 January 2020
View articletitled, A Transcriptionally Definable Subgroup of Triple-Negative Breast and Ovarian Cancer Samples Shows Sensitivity to HSP90 Inhibition
Open the PDF for A Transcriptionally Definable Subgroup of Triple-Negative Breast and Ovarian Cancer Samples Shows Sensitivity to HSP90 Inhibition in another window
Includes: Supplementary data
Journal Articles

Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha–Positive, PIK3CA-Mutant Breast Cancer

Wei Yang, Sarah R. Hosford, Lloye M. Dillon, Kevin Shee, Stephanie C. Liu, Jennifer R. Bean, Laurent Salphati, Jodie Pang, Xiaolin Zhang, Michelle A. Nannini, Eugene Demidenko, Darcy Bates, Lionel D. Lewis, Jonathan D. Marotti, Alan R. Eastman, Todd W. Miller
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (9): 2250–2260.
https://doi.org/10.1158/1078-0432.CCR-15-2276
Published: 01 May 2016
View articletitled, Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha–Positive, PIK3CA-Mutant Breast Cancer
Open the PDF for Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha–Positive, PIK3CA-Mutant Breast Cancer in another window
Includes: Supplementary data