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Kenneth Offit
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Journal Articles

Germline DNA Damage Repair Variants and Prognosis of Patients with High-Risk or Metastatic Prostate Cancer

Konrad H. Stopsack, Joseph Vijai, Michael Conry, Jacob E. Berchuck, Yelena Kemel, Samantha E. Vasselman, Dory A. Freeman, Gwo-Shu M. Lee, Diana Mandelker, David B. Solit, Michael J. Morris, Kathryn L. Penney, Wassim Abida, Kenneth Offit, Lorelei A. Mucci, Philip W. Kantoff, Mark M. Pomerantz
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (1): 122–129.
https://doi.org/10.1158/1078-0432.CCR-24-2483
Published: 06 January 2025
View articletitled, Germline DNA Damage Repair Variants and Prognosis of Patients with High-Risk or Metastatic Prostate Cancer
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Includes: Supplementary data
Journal Articles

NBN Pathogenic Germline Variants are Associated with Pan-Cancer Susceptibility and In Vitro DNA Damage Response Defects

Sami Belhadj, Aliya Khurram, Chaitanya Bandlamudi, Guillermo Palou-Márquez, Vignesh Ravichandran, Zoe Steinsnyder, Temima Wildman, Amanda Catchings, Yelena Kemel, Semanti Mukherjee, Benjamin Fesko, Kanika Arora, Miika Mehine, Sita Dandiker, Aalin Izhar, John Petrini, Susan Domchek, Katherine L. Nathanson, Jamie Brower, Fergus Couch, Zsofia Stadler, Mark Robson, Michael Walsh, Joseph Vijai, Michael Berger, Fran Supek, Rachid Karam, Sabine Topka, Kenneth Offit
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (2): 422–431.
https://doi.org/10.1158/1078-0432.CCR-22-1703
Published: 17 January 2023
View articletitled, NBN Pathogenic Germline Variants are Associated with Pan-Cancer Susceptibility and In Vitro DNA Damage Response Defects
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Includes: Supplementary data
Journal Articles

Inherited Germline Cancer Susceptibility Gene Variants in Individuals with Non–Muscle-Invasive Bladder Cancer

Eugene J. Pietzak, Karissa Whiting, Preethi Srinivasan, Chaitanya Bandlamudi, Aliya Khurram, Vijai Joseph, Aleksandra Walasek, Emily Bochner, Timothy Clinton, Nima Almassi, Hong Truong, Manuel R. de Jesus Escano, Michal Wiseman, Diana Mandelker, Yelena Kemel, Liying Zhang, Michael F. Walsh, Karen A. Cadoo, Jonathan A. Coleman, Hikmat Al-Ahmadie, Jonathan E. Rosenberg, Gopakumar V. Iyer, David B. Solit, Irina Ostrovnaya, Kenneth Offit, Mark E. Robson, Zsofia K. Stadler, Michael F. Berger, Dean F. Bajorin, Maria Carlo, Bernard H. Bochner
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (19): 4267–4277.
https://doi.org/10.1158/1078-0432.CCR-22-1006
Published: 03 October 2022
View articletitled, Inherited Germline Cancer Susceptibility Gene Variants in Individuals with Non–Muscle-Invasive Bladder Cancer
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Includes: Supplementary data
Journal Articles

Targeting Germline- and Tumor-Associated Nucleotide Excision Repair Defects in Cancer

Sabine Topka, Zoe Steinsnyder, Vignesh Ravichandran, Kaitlyn Tkachuk, Yelena Kemel, Chaitanya Bandlamudi, Mogens Winkel Madsen, Helena Furberg, Ouathek Ouerfelli, Charles M. Rudin, Gopa Iyer, Steven M. Lipkin, Semanti Mukherjee, David B. Solit, Michael F. Berger, Dean F. Bajorin, Jonathan E. Rosenberg, Barry S. Taylor, Elisa de Stanchina, Joseph Vijai, Kenneth Offit
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (7): 1997–2010.
https://doi.org/10.1158/1078-0432.CCR-20-3322
Published: 01 April 2021
View articletitled, Targeting Germline- and Tumor-Associated Nucleotide Excision Repair Defects in Cancer
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Includes: Supplementary data
Journal Articles

Characterization and Clinical Outcomes of DNA Mismatch Repair–deficient Small Bowel Adenocarcinoma

Alicia Latham, Jinru Shia, Zalak Patel, Diane L. Reidy-Lagunes, Neil H. Segal, Rona Yaeger, Karuna Ganesh, Louise Connell, Nancy E. Kemeny, David P. Kelsen, Jaclyn F. Hechtman, Garrett M. Nash, Philip B. Paty, Ahmet Zehir, Kaitlin A. Tkachuk, Rania Sheikh, Arnold J. Markowitz, Diana Mandelker, Kenneth Offit, Michael F. Berger, Andrea Cercek, Julio Garcia-Aguilar, Leonard B. Saltz, Martin R. Weiser, Zsofia K. Stadler
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (5): 1429–1437.
https://doi.org/10.1158/1078-0432.CCR-20-2892
Published: 01 March 2021
View articletitled, Characterization and Clinical Outcomes of DNA Mismatch Repair–deficient Small Bowel Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Susceptibility Loci Associated with Prostate Cancer Progression and Mortality

David J. Gallagher, Joseph Vijai, Angel M. Cronin, Jasmine Bhatia, Andrew J. Vickers, Mia M. Gaudet, Samson Fine, Victor Reuter, Howard I. Scher, Christer Halldén, Ana Dutra-Clarke, Robert J. Klein, Peter T. Scardino, James A. Eastham, Hans Lilja, Tomas Kirchhoff, Kenneth Offit
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (10): 2819–2832.
https://doi.org/10.1158/1078-0432.CCR-10-0028
Published: 13 May 2010
View articletitled, Susceptibility Loci Associated with Prostate Cancer Progression and Mortality
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Journal Articles

Germline BRCA Mutations Denote a Clinicopathologic Subset of Prostate Cancer

David J. Gallagher, Mia M. Gaudet, Prodipto Pal, Tomas Kirchhoff, Lisa Balistreri, Kinjal Vora, Jasmine Bhatia, Zsofia Stadler, Samson W. Fine, Victor Reuter, Michael Zelefsky, Michael J. Morris, Howard I. Scher, Robert J. Klein, Larry Norton, James A. Eastham, Peter T. Scardino, Mark E. Robson, Kenneth Offit
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (7): 2115–2121.
https://doi.org/10.1158/1078-0432.CCR-09-2871
Published: 31 March 2010
View articletitled, Germline BRCA Mutations Denote a Clinicopathologic Subset of Prostate Cancer
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Journal Articles

BRCA Mutations in Women with Ductal Carcinoma In situ

Karen Lisa Smith, Muriel Adank, Noah Kauff, Kelly Lafaro, Jeff Boyd, Johanna B. Lee, Clifford Hudis, Kenneth Offit, Mark Robson
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (14): 4306–4310.
https://doi.org/10.1158/1078-0432.CCR-07-0146
Published: 18 July 2007
View articletitled, BRCA Mutations in Women with Ductal Carcinoma In situ
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Journal Articles

BRCA Mutations and Risk of Prostate Cancer in Ashkenazi Jews

Tomas Kirchhoff, Noah D. Kauff, Nandita Mitra, Kedoudja Nafa, Helen Huang, Crystal Palmer, Tony Gulati, Eve Wadsworth, Sheri Donat, Mark E. Robson, Nathan A. Ellis, Kenneth Offit
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (9): 2918–2921.
https://doi.org/10.1158/1078-0432.CCR-03-0604
Published: 06 May 2004
View articletitled, BRCA Mutations and Risk of Prostate Cancer in Ashkenazi Jews
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Journal Articles

Pleomorphic Characteristics of a Germ-Line KIT Mutation in a Large Kindred with Gastrointestinal Stromal Tumors, Hyperpigmentation, and Dysphagia

Mark E. Robson, Emily Glogowski, Gunhild Sommer, Cristina R. Antonescu, Khedoudja Nafa, Robert G. Maki, Nathan Ellis, Peter Besmer, Murray Brennan, Kenneth Offit
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (4): 1250–1254.
https://doi.org/10.1158/1078-0432.CCR-03-0110
Published: 20 February 2004
View articletitled, Pleomorphic Characteristics of a Germ-Line KIT Mutation in a Large Kindred with Gastrointestinal Stromal Tumors, Hyperpigmentation, and Dysphagia
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Journal Articles

Ovarian Cancer Risk in Ashkenazi Jewish Carriers of BRCA1 and BRCA2 Mutations

Jaya M. Satagopan, Jeff Boyd, Noah D. Kauff, Mark Robson, Lauren Scheuer, Steven Narod, Kenneth Offit
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (12): 3776–3781.
Published: 01 December 2002
View articletitled, Ovarian Cancer Risk in Ashkenazi Jewish Carriers of BRCA1 and BRCA2 Mutations
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Journal Articles

Rare Variants of ATM and Risk for Hodgkin’s Disease and Radiation-associated Breast Cancers

Kenneth Offit, Shlomit Gilad, Shoshana Paglin, Prema Kolachana, Laila C. Roisman, Khedoudja Nafa, Vincent Yeugelewitz, Maria Gonzales, Mark Robson, Deborah McDermott, Heather Hanson Pierce, Noah D. Kauff, Paz Einat, Suresh Jhanwar, Jaya M. Satagopan, Carole Oddoux, Nathan Ellis, Rami Skaliter, Joachim Yahalom
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (12): 3813–3819.
Published: 01 December 2002
View articletitled, Rare Variants of ATM and Risk for Hodgkin’s Disease and Radiation-associated Breast Cancers
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