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Kenneth D. Aldape
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Journal Articles

Tissue 2-Hydroxyglutarate as a Biomarker for Isocitrate Dehydrogenase Mutations in Gliomas

Hao-Wen Sim, Romina Nejad, Wenjiang Zhang, Farshad Nassiri, Warren Mason, Kenneth D. Aldape, Gelareh Zadeh, Eric X. Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (11): 3366–3373.
https://doi.org/10.1158/1078-0432.CCR-18-3205
Published: 03 June 2019
View article titled, Tissue 2-Hydroxyglutarate as a Biomarker for <em>Isocitrate Dehydrogenase</em> Mutations in Gliomas
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Includes: Supplementary data
Journal Articles

Ketoconazole and Posaconazole Selectively Target HK2-expressing Glioblastoma Cells

Sameer Agnihotri, Sheila Mansouri, Kelly Burrell, Mira Li, Yasin Mamatjan, Jeff Liu, Romina Nejad, Sushil Kumar, Shahrzad Jalali, Sanjay K. Singh, Alenoush Vartanian, Eric Xueyu Chen, Shirin Karimi, Olivia Singh, Severa Bunda, Alireza Mansouri, Kenneth D. Aldape, Gelareh Zadeh
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (2): 844–855.
https://doi.org/10.1158/1078-0432.CCR-18-1854
Published: 15 January 2019
View article titled, Ketoconazole and Posaconazole Selectively Target HK2-expressing Glioblastoma Cells
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Includes: Supplementary data
Journal Articles

The Evolving Role of Molecular Markers in the Diagnosis and Management of Diffuse Glioma

Jason T. Huse, Kenneth D. Aldape
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (22): 5601–5611.
https://doi.org/10.1158/1078-0432.CCR-14-0831
Published: 13 November 2014
View article titled, The Evolving Role of Molecular Markers in the Diagnosis and Management of Diffuse Glioma
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Journal Articles

Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target

Guo Chen, Nitin Chakravarti, Kimberly Aardalen, Alexander J. Lazar, Michael T. Tetzlaff, Bradley Wubbenhorst, Sang-Bae Kim, Scott Kopetz, Alicia A. Ledoux, Y.N. Vashisht Gopal, Cristiano Goncalves Pereira, Wanleng Deng, Ju-Seog Lee, Katherine L. Nathanson, Kenneth D. Aldape, Victor G. Prieto, Darrin Stuart, Michael A. Davies
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (21): 5537–5546.
https://doi.org/10.1158/1078-0432.CCR-13-3003
Published: 30 October 2014
View article titled, Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target
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Includes: Supplementary data
Journal Articles

Tumor-Infiltrating Lymphocytes in Glioblastoma Are Associated with Specific Genomic Alterations and Related to Transcriptional Class

W. Caleb Rutledge, Jun Kong, Jingjing Gao, David A. Gutman, Lee A.D. Cooper, Christina Appin, Yuna Park, Lisa Scarpace, Tom Mikkelsen, Mark L. Cohen, Kenneth D. Aldape, Roger E. McLendon, Norman L. Lehman, C. Ryan Miller, Matthew J. Schniederjan, Cameron W. Brennan, Joel H. Saltz, Carlos S. Moreno, Daniel J. Brat
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (18): 4951–4960.
https://doi.org/10.1158/1078-0432.CCR-13-0551
Published: 16 September 2013
View article titled, Tumor-Infiltrating Lymphocytes in Glioblastoma Are Associated with Specific Genomic Alterations and Related to Transcriptional Class
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Journal Articles

New Strategies in Melanoma: Molecular Testing in Advanced Disease

Scott E. Woodman, Alexander J. Lazar, Kenneth D. Aldape, Michael A. Davies
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (5): 1195–1200.
https://doi.org/10.1158/1078-0432.CCR-11-2317
Published: 01 March 2012
View article titled, New Strategies in Melanoma: Molecular Testing in Advanced Disease
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Journal Articles

HER Family Receptor Abnormalities in Lung Cancer Brain Metastases and Corresponding Primary Tumors

Menghong Sun, Carmen Behrens, Lei Feng, Natalie Ozburn, Ximing Tang, Guosheng Yin, Ritsuko Komaki, Marileila Varella-Garcia, Waun Ki Hong, Kenneth D. Aldape, Ignacio I. Wistuba
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (15): 4829–4837.
https://doi.org/10.1158/1078-0432.CCR-08-2921
Published: 29 July 2009
View article titled, HER Family Receptor Abnormalities in Lung Cancer Brain Metastases and Corresponding Primary Tumors
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Includes: Supplementary data
Journal Articles

Polymorphisms in the Interleukin-4 Receptor Gene are Associated with Better Survival in Patients with Glioblastoma

Michael E. Scheurer, E. Amirian, Yumei Cao, Mark R. Gilbert, Kenneth D. Aldape, David G. Kornguth, Randa El-Zein, Melissa L. Bondy
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (20): 6640–6646.
https://doi.org/10.1158/1078-0432.CCR-07-4681
Published: 16 October 2008
View article titled, Polymorphisms in the <em>Interleukin-4 Receptor</em> Gene are Associated with Better Survival in Patients with Glioblastoma
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Journal Articles

Phase I Study of Temozolomide and Irinotecan for Recurrent Malignant Gliomas in Patients Receiving Enzyme-Inducing Antiepileptic Drugs: A North American Brain Tumor Consortium Study

Monica E. Loghin, Michael D. Prados, Patrick Wen, Larry Junck, Frank Lieberman, Howard Fine, Karen L. Fink, Minesh Metha, John Kuhn, Kathleen Lamborn, Susan M. Chang, Timothy Cloughesy, Lisa M. DeAngelis, Ian H. Robins, Kenneth D. Aldape, W.K. Alfred Yung
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (23): 7133–7138.
https://doi.org/10.1158/1078-0432.CCR-07-0874
Published: 03 December 2007
View article titled, Phase I Study of Temozolomide and Irinotecan for Recurrent Malignant Gliomas in Patients Receiving Enzyme-Inducing Antiepileptic Drugs: A North American Brain Tumor Consortium Study
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Journal Articles

Phosphorylated Pak1 Level in the Cytoplasm Correlates with Shorter Survival Time in Patients with Glioblastoma

Hiroshi Aoki, Tomohisa Yokoyama, Keishi Fujiwara, Ana M. Tari, Raymond Sawaya, Dima Suki, Kenneth R. Hess, Kenneth D. Aldape, Seiji Kondo, Rakesh Kumar, Yasuko Kondo
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (22): 6603–6609.
https://doi.org/10.1158/1078-0432.CCR-07-0145
Published: 15 November 2007
View article titled, Phosphorylated Pak1 Level in the Cytoplasm Correlates with Shorter Survival Time in Patients with Glioblastoma
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Journal Articles

Mutations Within the Kinase Domain and Truncations of the Epidermal Growth Factor Receptor Are Rare Events in Bladder Cancer: Implications for Therapy

Kelly N. Blehm, Philippe E. Spiess, Jolanta E. Bondaruk, Melanie E. Dujka, Gabriel J. Villares, Yi-jue Zhao, Oliver Bogler, Kenneth D. Aldape, H. Barton Grossman, Liana Adam, David J. McConkey, Bogdan A. Czerniak, Colin P. Dinney, Menashe Bar-Eli
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (15): 4671–4677.
https://doi.org/10.1158/1078-0432.CCR-06-0407
Published: 09 August 2006
View article titled, Mutations Within the Kinase Domain and Truncations of the Epidermal Growth Factor Receptor Are Rare Events in Bladder Cancer: Implications for Therapy
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Journal Articles

Prognostic Associations of Activated Mitogen-Activated Protein Kinase and Akt Pathways in Glioblastoma

Christopher E. Pelloski, E Lin, Li Zhang, W.K. Alfred Yung, Howard Colman, Juinn-Lin Liu, Shaio Y. Woo, Amy B. Heimberger, Dima Suki, Michael Prados, Susan Chang, Fredrick G. Barker, III, Gregory N. Fuller, Kenneth D. Aldape
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (13): 3935–3941.
https://doi.org/10.1158/1078-0432.CCR-05-2202
Published: 03 July 2006
View article titled, Prognostic Associations of Activated Mitogen-Activated Protein Kinase and Akt Pathways in Glioblastoma
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Journal Articles

YKL-40 Expression is Associated with Poorer Response to Radiation and Shorter Overall Survival in Glioblastoma

Christopher E. Pelloski, Anita Mahajan, Moshe Maor, Eric L. Chang, Shiao Woo, Mark Gilbert, Howard Colman, Helen Yang, Alicia Ledoux, Hilary Blair, Sandra Passe, Robert B. Jenkins, Kenneth D. Aldape
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (9): 3326–3334.
https://doi.org/10.1158/1078-0432.CCR-04-1765
Published: 02 May 2005
View article titled, YKL-40 Expression is Associated with Poorer Response to Radiation and Shorter Overall Survival in Glioblastoma
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Journal Articles

Expression of Activated Signal Transducer and Activator of Transcription 3 Predicts Expression of Vascular Endothelial Growth Factor in and Angiogenic Phenotype of Human Gastric Cancer

Weida Gong, Liwei Wang, James C. Yao, Jaffer A. Ajani, Daoyan Wei, Kenneth D. Aldape, Keping Xie, Raymond Sawaya, Suyun Huang
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (4): 1386–1393.
https://doi.org/10.1158/1078-0432.CCR-04-0487
Published: 02 March 2005
View article titled, Expression of Activated Signal Transducer and Activator of Transcription 3 Predicts Expression of Vascular Endothelial Growth Factor in and Angiogenic Phenotype of Human Gastric Cancer
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