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Kenneth Aldape
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Journal Articles

Abstract B047: Path2Space: An AI approach for cancer biomarker discovery via histopathology inferred spatial transcriptomics

Free
Emma M. Campagnolo, Eldad D. Shulman, Roshan Lodha, Amos Stemmer, Peng Jiang, Carlos Caldas, Simon Knott, Danh-Tai Hoang, Kenneth Aldape, Eytan Ruppin
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (13_Supplement): B047.
https://doi.org/10.1158/1557-3265.AIMACHINE-B047
Published: 10 July 2025
View article titled, Abstract B047: Path2Space: An AI approach for cancer biomarker discovery via histopathology inferred spatial transcriptomics
Journal Articles

Response Rate and Molecular Correlates to Encorafenib and Binimetinib in BRAF-V600E Mutant High-Grade Glioma

Free
Karisa C. Schreck, Roy E. Strowd, Louis B. Nabors, Benjamin M. Ellingson, Michael Chang, Sze K. Tan, Zied Abdullaev, Rust Turakulov, Kenneth Aldape, Neeraja Danda, Serena Desideri, Joy Fisher, Michaella Iacoboni, Trisha Surakus, Michelle A. Rudek, Chetan Bettegowda, Stuart A. Grossman, Xiaobu Ye
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (10): 2048–2056.
https://doi.org/10.1158/1078-0432.CCR-23-3241
Published: 15 May 2024
View article titled, Response Rate and Molecular Correlates to Encorafenib and Binimetinib in BRAF-V600E Mutant High-Grade Glioma
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Includes: Supplementary data
Journal Articles

Temozolomide and Radiotherapy versus Radiotherapy Alone in Patients with Glioblastoma, IDH-wildtype: Post Hoc Analysis of the EORTC Randomized Phase III CATNON Trial

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C. Mircea S. Tesileanu, Marc Sanson, Wolfgang Wick, Alba A. Brandes, Paul M. Clement, Sara C. Erridge, Michael A. Vogelbaum, Anna K. Nowak, Jean-Francois Baurain, Warren P. Mason, Helen Wheeler, Olivier L. Chinot, Sanjeev Gill, Matthew Griffin, Leland Rogers, Walter Taal, Roberta Rudà, Michael Weller, Catherine McBain, Myra E. van Linde, Kenneth Aldape, Robert B. Jenkins, Johan M. Kros, Pieter Wesseling, Andreas von Deimling, Youri Hoogstrate, Iris de Heer, Peggy N. Atmodimedjo, Hendrikus J. Dubbink, Rutger W.W. Brouwer, Wilfred F.J. van IJcken, Kin Jip Cheung, Vassilis Golfinopoulos, Brigitta G. Baumert, Thierry Gorlia, Pim J. French, Martin J. van den Bent
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (12): 2527–2535.
https://doi.org/10.1158/1078-0432.CCR-21-4283
Published: 13 June 2022
View article titled, Temozolomide and Radiotherapy versus Radiotherapy Alone in Patients with Glioblastoma, IDH-wildtype: Post Hoc Analysis of the EORTC Randomized Phase III CATNON Trial
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Includes: Supplementary data
Journal Articles

Abstract PO-060: Individualized prediction of meningioma recurrence risk over prolonged time periods

Free
Yasin Mamatjan, Farshad Nassiri, Mira Salih, Kenneth Aldape, Gelareh Zadeh
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (5_Supplement): PO-060.
https://doi.org/10.1158/1557-3265.ADI21-PO-060
Published: 01 March 2021
View article titled, Abstract PO-060: Individualized prediction of meningioma recurrence risk over prolonged time periods
Journal Articles

Macitentan, a Dual Endothelin Receptor Antagonist, in Combination with Temozolomide Leads to Glioblastoma Regression and Long-term Survival in Mice

Free
Sun-Jin Kim, Ho Jeong Lee, Mark Seungwook Kim, Hyun Jin Choi, Junqin He, Qiuyu Wu, Kenneth Aldape, Jeffrey S. Weinberg, W.K. Alfred Yung, Charles A. Conrad, Robert R. Langley, François Lehembre, Urs Regenass, Isaiah J. Fidler
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2015) 21 (20): 4630–4641.
https://doi.org/10.1158/1078-0432.CCR-14-3195
Published: 14 October 2015
View article titled, Macitentan, a Dual Endothelin Receptor Antagonist, in Combination with Temozolomide Leads to Glioblastoma Regression and Long-term Survival in Mice
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Includes: Supplementary data
Journal Articles

Personalized Medicine for Patients with Advanced Cancer in the Phase I Program at MD Anderson: Validation and Landmark Analyses

Free
Apostolia-Maria Tsimberidou, Sijin Wen, David S. Hong, Jennifer J. Wheler, Gerald S. Falchook, Siqing Fu, Sarina Piha-Paul, Aung Naing, Filip Janku, Kenneth Aldape, Yang Ye, Razelle Kurzrock, Donald Berry
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (18): 4827–4836.
https://doi.org/10.1158/1078-0432.CCR-14-0603
Published: 14 September 2014
View article titled, Personalized Medicine for Patients with Advanced Cancer in the Phase I Program at MD Anderson: Validation and Landmark Analyses
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Includes: Supplementary data
Journal Articles

An intermediate methylation signature is associated with improved patient survival and a distinct global mRNA expression profile in glioblastoma: An interim analysis of The Cancer Genome Atlas data

Free
Christopher Pelloski, Andreana Rivera, Krishna Bhat, Erik Sulman, WK Alfred Yung, Jonas Almeida, Pablo Fiere, Mark Gilbert, Steven Baylin, Peter Laird, Kenneth Aldape
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (19_Supplement): PL04.
Published: 15 August 2014
View article titled, An intermediate methylation signature is associated with improved patient survival and a distinct global mRNA expression profile in glioblastoma: An interim analysis of The Cancer Genome Atlas data
Journal Articles

Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma

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Michael A. Davies, Katherine Stemke-Hale, E. Lin, Carmen Tellez, Wanleng Deng, Yennu N. Gopal, Scott E. Woodman, Tiffany C. Calderone, Zhenlin Ju, Alexander J. Lazar, Victor G. Prieto, Kenneth Aldape, Gordon B. Mills, Jeffrey E. Gershenwald
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (24): 7538–7546.
https://doi.org/10.1158/1078-0432.CCR-09-1985
Published: 14 December 2009
View article titled, Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma
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Includes: Supplementary data
Journal Articles

Phase I/II Study of Imatinib Mesylate for Recurrent Malignant Gliomas: North American Brain Tumor Consortium Study 99-08

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Patrick Y. Wen, W.K. Alfred Yung, Kathleen R. Lamborn, Patricia L. Dahia, Yanfeng Wang, Bin Peng, Lauren E. Abrey, Jeffrey Raizer, Timothy F. Cloughesy, Karen Fink, Mark Gilbert, Susan Chang, Larry Junck, David Schiff, Frank Lieberman, Howard A. Fine, Minesh Mehta, H. Ian Robins, Lisa M. DeAngelis, Morris D. Groves, Vinay K. Puduvalli, Victor Levin, Charles Conrad, Elizabeth A. Maher, Kenneth Aldape, Michael Hayes, Laurie Letvak, Merrill J. Egorin, Renaud Capdeville, Richard Kaplan, Anthony J. Murgo, Charles Stiles, Michael D. Prados
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (16): 4899–4907.
https://doi.org/10.1158/1078-0432.CCR-06-0773
Published: 16 August 2006
View article titled, Phase I/II Study of Imatinib Mesylate for Recurrent Malignant Gliomas: North American Brain Tumor Consortium Study 99-08
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Journal Articles

Prognostic Effect of Epidermal Growth Factor Receptor and EGFRvIII in Glioblastoma Multiforme Patients

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Amy B. Heimberger, Roman Hlatky, Dima Suki, David Yang, Jeff Weinberg, Mark Gilbert, Raymond Sawaya, Kenneth Aldape
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (4): 1462–1466.
https://doi.org/10.1158/1078-0432.CCR-04-1737
Published: 02 March 2005
View article titled, Prognostic Effect of Epidermal Growth Factor Receptor and EGFRvIII in Glioblastoma Multiforme Patients
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