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Kelly K. Hunt
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Journal Articles

A Preoperative Window-of-Opportunity Study of Oral SERD, Imlunestrant, in Newly Diagnosed ER-Positive, HER2-Negative Early Breast Cancer: Results from the EMBER-2 Study

Patrick Neven, Nicole Stahl, Maria Vidal, Miguel Martín, Peter A. Kaufman, Nadia Harbeck, Kelly K. Hunt, Stacey Carter, Francois-Clement Bidard, Peter A. Fasching, Philippe Aftimos, Duncan Wheatley, Erika Hamilton, Rebecca Aft, Swati Kulkarni, Peter Schmid, Manali Bhave, Roohi Ismail-Khan, Claudia Karacsonyi, Shawn T. Estrem, Bastien Nguyen, Umut Ozbek, Eunice Yuen, Vanessa Rodrik-Outmezguine, Eva Ciruelos
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (23): 5304–5313.
https://doi.org/10.1158/1078-0432.CCR-24-2113
Published: 02 December 2024
View article titled, A Preoperative Window-of-Opportunity Study of Oral SERD, Imlunestrant, in Newly Diagnosed ER-Positive, HER2-Negative Early Breast Cancer: Results from the EMBER-2 Study
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Includes: Supplementary data
Journal Articles

Abstract PR002: Antigen presentation and processing pathway is associated with early relapse after neoadjuvant immune checkpoint blockade (ICB) in dedifferentiated liposarcomas (DDLPS)

Elise F. Nassif, Chia-Chin Wu, Kadir Akdemir, Russell G. Witt, Raymond Traweek, Brandon Cope, Prapassorn Thirasastr, Taylor Tate, Grace Mathew, Shadarra Crosby, Randy Chu, Mohammad Mohammad, Kenna Shaw, Ingram Davis, Khalida Wani, Alexander J. Lazar, Wei-Lien Wang, Sheila Duncan, Ashleigh B. Guadagnolo, Andrew J. Bishop, Valerae Lewis, Justin E. Bird, Keila E. Torres, Kelly K. Hunt, Barry W. Feig, Christopher P. Scally, Ravin Ratan, Shreyaskumar Patel, Robert S. Benjamin, Robert Satcher, Kevin McBride, Wolf H. Fridman, Ignacio Wistuba, Andrew Futreal, Jennifer A. Wargo, Neeta Somaiah, Christina L. Roland, Emily Z. Keung
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (18_Supplement): PR002.
https://doi.org/10.1158/1557-3265.SARCOMAS22-PR002
Published: 15 September 2022
View article titled, Abstract PR002: Antigen presentation and processing pathway is associated with early relapse after neoadjuvant immune checkpoint blockade (ICB) in dedifferentiated liposarcomas (DDLPS)
Journal Articles

Evaluation of Sensitivity to Endocrine Therapy Index (SET2,3) for Response to Neoadjuvant Endocrine Therapy and Longer-Term Breast Cancer Patient Outcomes (Alliance Z1031)

Vera J. Suman, Lili Du, Tanya Hoskin, Meenakshi Anurag, Cynthia Ma, Isabelle Bedrosian, Kelly K. Hunt, Matthew J. Ellis, W. Fraser Symmans
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (15): 3287–3295.
https://doi.org/10.1158/1078-0432.CCR-22-0068
Published: 02 August 2022
View article titled, Evaluation of Sensitivity to Endocrine Therapy Index (SET2,3) for Response to Neoadjuvant Endocrine Therapy and Longer-Term Breast Cancer Patient Outcomes (Alliance Z1031)
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Includes: Supplementary data
Journal Articles

Combined Inhibition of STAT3 and DNA Repair in Palbociclib-Resistant ER-Positive Breast Cancer

Nicole M. Kettner, Smruthi Vijayaraghavan, Merih Guray Durak, Tuyen Bui, Mehrnoosh Kohansal, Min Jin Ha, Bin Liu, Xiayu Rao, Jing Wang, Min Yi, Jason P.W. Carey, Xian Chen, T. Kris Eckols, Akshara S. Raghavendra, Nuhad K. Ibrahim, Meghan Sri Karuturi, Stephanie S. Watowich, Aysegul Sahin, David J. Tweardy, Kelly K. Hunt, Debu Tripathy, Khandan Keyomarsi
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (13): 3996–4013.
https://doi.org/10.1158/1078-0432.CCR-18-3274
Published: 01 July 2019
View article titled, Combined Inhibition of STAT3 and DNA Repair in Palbociclib-Resistant ER-Positive Breast Cancer
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Includes: Supplementary data
Journal Articles

Cyclin E Overexpression Sensitizes Triple-Negative Breast Cancer to Wee1 Kinase Inhibition

Xian Chen, Kwang-Huei Low, Angela Alexander, Yufeng Jiang, Cansu Karakas, Kenneth R. Hess, Jason P.W. Carey, Tuyen N. Bui, Smruthi Vijayaraghavan, Kurt W. Evans, Min Yi, D. Christian Ellis, Kwok-Leung Cheung, Ian O. Ellis, Siqing Fu, Funda Meric-Bernstam, Kelly K. Hunt, Khandan Keyomarsi
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (24): 6594–6610.
https://doi.org/10.1158/1078-0432.CCR-18-1446
Published: 13 December 2018
View article titled, Cyclin E Overexpression Sensitizes Triple-Negative Breast Cancer to Wee1 Kinase Inhibition
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Includes: Supplementary data
Journal Articles

Abstract B27: Analysis of the immune infiltrate in undifferentiated pleomorphic sarcoma of the extremity and trunk in response to radiotherapy

Emily Z. Keung, Jen-Wei Tsai, Ali M. Ali, Janice N. Cormier, Andrew J. Bishop, B. Ashleigh Guadagnolo, Kelly K. Hunt, Keila E. Torres, Neeta Somaiah, Jennifer A. Wargo, Alexander Lazar, Wei-Lien Wang, Cristina L. Roland
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (2_Supplement): B27.
https://doi.org/10.1158/1557-3265.SARCOMAS17-B27
Published: 15 January 2018
View article titled, Abstract B27: Analysis of the immune infiltrate in undifferentiated pleomorphic sarcoma of the extremity and trunk in response to radiotherapy
Journal Articles

Cytoplasmic Cyclin E Mediates Resistance to Aromatase Inhibitors in Breast Cancer

Iman Doostan, Cansu Karakas, Mehrnoosh Kohansal, Kwang-Hui Low, Matthew J. Ellis, John A. Olson, Jr., Vera J. Suman, Kelly K. Hunt, Stacy L. Moulder, Khandan Keyomarsi
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (23): 7288–7300.
https://doi.org/10.1158/1078-0432.CCR-17-1544
Published: 30 November 2017
View article titled, Cytoplasmic Cyclin E Mediates Resistance to Aromatase Inhibitors in Breast Cancer
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Includes: Supplementary data
Journal Articles

Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer

Kelly K. Hunt, Cansu Karakas, Min Jin Ha, Anna Biernacka, Min Yi, Aysegul A. Sahin, Opoku Adjapong, Gabriel N. Hortobagyi, Melissa L. Bondy, Patricia A. Thompson, Kwok Leung Cheung, Ian O. Ellis, Sarah Bacus, W. Fraser Symmans, Kim-Anh Do, Khandan Keyomarsi
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (12): 2991–3002.
https://doi.org/10.1158/1078-0432.CCR-16-2217
Published: 14 June 2017
View article titled, Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer
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Includes: Supplementary data
Journal Articles

Relationship between Complete Pathologic Response to Neoadjuvant Chemotherapy and Survival in Triple-Negative Breast Cancer

Christos Hatzis, W. Fraser Symmans, Ya Zhang, Rebekah E. Gould, Stacy L. Moulder, Kelly K. Hunt, Maysa Abu-Khalaf, Erin W. Hofstatter, Donald Lannin, Anees B. Chagpar, Lajos Pusztai
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (1): 26–33.
https://doi.org/10.1158/1078-0432.CCR-14-3304
Published: 03 January 2016
View article titled, Relationship between Complete Pathologic Response to Neoadjuvant Chemotherapy and Survival in Triple-Negative Breast Cancer
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Includes: Supplementary data
Journal Articles

Dual Targeting of mTOR and Aurora-A Kinase for the Treatment of Uterine Leiomyosarcoma

Kari J. Brewer Savannah, Elizabeth G. Demicco, Kristelle Lusby, Markus PH. Ghadimi, Roman Belousov, Eric Young, Yiqun Zhang, Kai-Lieh Huang, Alexander J. Lazar, Kelly K. Hunt, Raphael E. Pollock, Chad J. Creighton, Matthew L. Anderson, Dina Lev
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (17): 4633–4645.
https://doi.org/10.1158/1078-0432.CCR-12-0436
Published: 30 August 2012
View article titled, Dual Targeting of mTOR and Aurora-A Kinase for the Treatment of Uterine Leiomyosarcoma
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Includes: Supplementary data
Journal Articles

Low-Molecular-Weight Cyclin E Can Bypass Letrozole-Induced G1 Arrest in Human Breast Cancer Cells and Tumors

Said Akli, Tuyen Bui, Hannah Wingate, Anna Biernacka, Stacy Moulder, Susan L. Tucker, Kelly K. Hunt, Khandan Keyomarsi
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (4): 1179–1190.
https://doi.org/10.1158/1078-0432.CCR-09-1787
Published: 15 February 2010
View article titled, Low-Molecular-Weight Cyclin E Can Bypass Letrozole-Induced G<sub>1</sub> Arrest in Human Breast Cancer Cells and Tumors
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Includes: Supplementary data
Journal Articles

Loss of HER2 Amplification Following Trastuzumab-Based Neoadjuvant Systemic Therapy and Survival Outcomes

Elizabeth A. Mittendorf, Yun Wu, Maurizio Scaltriti, Funda Meric-Bernstam, Kelly K. Hunt, Shaheenah Dawood, Francisco J. Esteva, Aman U. Buzdar, Huiqin Chen, Sameena Eksambi, Gabriel N. Hortobagyi, Jose Baselga, Ana M. Gonzalez-Angulo
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (23): 7381–7388.
https://doi.org/10.1158/1078-0432.CCR-09-1735
Published: 30 November 2009
View article titled, Loss of <em>HER2</em> Amplification Following Trastuzumab-Based Neoadjuvant Systemic Therapy and Survival Outcomes
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Journal Articles

Increased Vascular Endothelial Growth Factor-C Expression Is Insufficient to Induce Lymphatic Metastasis in Human Soft-Tissue Sarcomas

Guy Lahat, Alexander Lazar, Xuemei Wang, Wei-Lien Wang, Quan-Sheng Zhu, Kelly K. Hunt, Raphael E. Pollock, Dina Lev
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (8): 2637–2646.
https://doi.org/10.1158/1078-0432.CCR-08-2442
Published: 15 April 2009
View article titled, Increased Vascular Endothelial Growth Factor-C Expression Is Insufficient to Induce Lymphatic Metastasis in Human Soft-Tissue Sarcomas
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Journal Articles

Phase I/II Study of G3139 (Bcl-2 Antisense Oligonucleotide) in Combination with Doxorubicin and Docetaxel in Breast Cancer

Stacy L. Moulder, W. Fraser Symmans, Daniel J. Booser, Timothy L. Madden, Cindy Lipsanen, Linda Yuan, Abenaa M. Brewster, Massimo Cristofanilli, Kelly K. Hunt, Thomas A. Buchholz, James Zwiebel, Vicente Valero, Gabriel N. Hortobagyi, Francisco J. Esteva
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (23): 7909–7916.
https://doi.org/10.1158/1078-0432.CCR-08-1104
Published: 01 December 2008
View article titled, Phase I/II Study of G3139 (Bcl-2 Antisense Oligonucleotide) in Combination with Doxorubicin and Docetaxel in Breast Cancer
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Journal Articles

The Double-Stranded RNA-Activated Protein Kinase Mediates Radiation Resistance in Mouse Embryo Fibroblasts through Nuclear Factor κB and Akt Activation

Urs von Holzen, Abujiang Pataer, Uma Raju, Dora Bocangel, Stephan A. Vorburger, Yanna Liu, Xiaolin Lu, Jack A. Roth, Bharat B. Aggarwal, Glen N. Barber, Khandan Keyomarsi, Kelly K. Hunt, Stephen G. Swisher
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (20): 6032–6039.
https://doi.org/10.1158/1078-0432.CCR-06-2932
Published: 18 October 2007
View article titled, The Double-Stranded RNA-Activated Protein Kinase Mediates Radiation Resistance in Mouse Embryo Fibroblasts through Nuclear Factor κB and Akt Activation
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Journal Articles

Neoadjuvant Therapy with Paclitaxel followed by 5-Fluorouracil, Epirubicin, and Cyclophosphamide Chemotherapy and Concurrent Trastuzumab in Human Epidermal Growth Factor Receptor 2–Positive Operable Breast Cancer: An Update of the Initial Randomized Study Population and Data of Additional Patients Treated with the Same Regimen

Aman U. Buzdar, Vicente Valero, Nuhad K. Ibrahim, Deborah Francis, Kristine R. Broglio, Richard L. Theriault, Lajos Pusztai, Marjorie C. Green, Sonja E. Singletary, Kelly K. Hunt, Aysegul A. Sahin, Francisco Esteva, William F. Symmans, Michael S. Ewer, Thomas A. Buchholz, Gabriel N. Hortobagyi
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (1): 228–233.
https://doi.org/10.1158/1078-0432.CCR-06-1345
Published: 02 January 2007
View article titled, Neoadjuvant Therapy with Paclitaxel followed by 5-Fluorouracil, Epirubicin, and Cyclophosphamide Chemotherapy and Concurrent Trastuzumab in Human Epidermal Growth Factor Receptor 2–Positive Operable Breast Cancer: An Update of the Initial Randomized Study Population and Data of Additional Patients Treated with the Same Regimen
Open the PDF for Neoadjuvant Therapy with Paclitaxel followed by 5-Fluorouracil, Epirubicin, and Cyclophosphamide Chemotherapy and Concurrent Trastuzumab in Human Epidermal Growth Factor Receptor 2–Positive Operable Breast Cancer: An Update of the Initial Randomized Study Population and Data of Additional Patients Treated with the Same Regimen in another window
Journal Articles

High and Differential Expression of HER-2 /neu Extracellular Domain in Bilateral Ductal Fluids from Women with Unilateral Invasive Breast Cancer

Henry M. Kuerer, Patricia A. Thompson, Savitri Krishnamurthy, Herbert A. Fritsche, Sylvie M. Marcy, Gildy V. Babiera, S. Eva Singletary, Massimo Cristofanilli, Nour Sneige, Kelly K. Hunt
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (2): 601–605.
Published: 01 February 2003
View article titled, High and Differential Expression of HER-2 <em>/neu</em> Extracellular Domain in Bilateral Ductal Fluids from Women with Unilateral Invasive Breast Cancer
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