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Kari Wilder-Romans
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Journal Articles

Abstract PO-028: RB loss mitigates CDK4/6 inhibitor-mediated radiosensitization of estrogen receptor positive (ER+) breast cancers

Andrea M. Pesch, Nicole Hirsh, Anna R. Michmerhuizen, Benjamin C. Chandler, Kari Wilder-Romans, Meilan Liu, Erin Cobain, Lori J. Pierce, James M. Rae, Corey Speers
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (8_Supplement): PO-028.
https://doi.org/10.1158/1557-3265.RADSCI21-PO-028
Published: 15 April 2021
View article titled, Abstract PO-028: RB loss mitigates CDK4/6 inhibitor-mediated radiosensitization of estrogen receptor positive (ER+) breast cancers
Journal Articles

Abstract PO-008: Mechanistic and therapeutic links between purine biosynthesis and DNA damage in glioblastoma

Andrew J. Scott, Weihua Zhou, Kari Wilder-Romans, Anthony C. Andren, Li Zhang, Yoshie Umemura, Nathan Qi, Theodore S. Lawrence, Costas A. Lyssiotis, Daniel R Wahl
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (8_Supplement): PO-008.
https://doi.org/10.1158/1557-3265.RADSCI21-PO-008
Published: 15 April 2021
View article titled, Abstract PO-008: Mechanistic and therapeutic links between purine biosynthesis and DNA damage in glioblastoma
Journal Articles

Short-term CDK4/6 Inhibition Radiosensitizes Estrogen Receptor–Positive Breast Cancers

Andrea M. Pesch, Nicole H. Hirsh, Benjamin C. Chandler, Anna R. Michmerhuizen, Cassandra L. Ritter, Marlie P. Androsiglio, Kari Wilder-Romans, Meilan Liu, Christina L. Gersch, José M. Larios, Lori J. Pierce, James M. Rae, Corey W. Speers
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (24): 6568–6580.
https://doi.org/10.1158/1078-0432.CCR-20-2269
Published: 15 December 2020
View article titled, Short-term CDK4/6 Inhibition Radiosensitizes Estrogen Receptor–Positive Breast Cancers
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Includes: Supplementary data
Journal Articles

DNA-Dependent Protein Kinase Drives Prostate Cancer Progression through Transcriptional Regulation of the Wnt Signaling Pathway

Vishal Kothari, Jonathan F. Goodwin, Shuang G. Zhao, Justin M. Drake, Yi Yin, S. Laura Chang, Joseph R. Evans, Kari Wilder-Romans, Kristina Gabbara, Emanuela Dylgjeri, Jonathan Chou, Grace Sun, Scott A. Tomlins, Rohit Mehra, Kristen Hege, Ellen H. Filvaroff, Edward M. Schaeffer, R. Jeffrey Karnes, David A. Quigley, Dana E. Rathkopf, Housheng H. He, Corey Speers, Daniel E. Spratt, Luke A. Gilbert, Alan Ashworth, Arul M. Chinnaiyan, Ganesh V. Raj, Karen E. Knudsen, Felix Y. Feng
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (18): 5608–5622.
https://doi.org/10.1158/1078-0432.CCR-18-2387
Published: 13 September 2019
View article titled, DNA-Dependent Protein Kinase Drives Prostate Cancer Progression through Transcriptional Regulation of the Wnt Signaling Pathway
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Journal Articles

Functional and Mechanistic Interrogation of BET Bromodomain Degraders for the Treatment of Metastatic Castration-resistant Prostate Cancer

Steven Kregel, Rohit Malik, Irfan A. Asangani, Kari Wilder-Romans, Thekkelnaycke Rajendiran, Lanbo Xiao, Josh N. Vo, Tanu Soni, Marcin Cieslik, Ester Fernadez-Salas, Bing Zhou, Xuhong Cao, Corey Speers, Shaomeng Wang, Arul M. Chinnaiyan
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (13): 4038–4048.
https://doi.org/10.1158/1078-0432.CCR-18-3776
Published: 01 July 2019
View article titled, Functional and Mechanistic Interrogation of BET Bromodomain Degraders for the Treatment of Metastatic Castration-resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Maternal Embryonic Leucine Zipper Kinase (MELK) as a Novel Mediator and Biomarker of Radioresistance in Human Breast Cancer

Corey Speers, Shuang G. Zhao, Vishal Kothari, Alyssa Santola, Meilan Liu, Kari Wilder-Romans, Joseph Evans, Nidhi Batra, Harry Bartelink, Daniel F. Hayes, Theodore S. Lawrence, Powel H. Brown, Lori J. Pierce, Felix Y. Feng
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (23): 5864–5875.
https://doi.org/10.1158/1078-0432.CCR-15-2711
Published: 30 November 2016
View article titled, Maternal Embryonic Leucine Zipper Kinase (MELK) as a Novel Mediator and Biomarker of Radioresistance in Human Breast Cancer
Open the PDF for Maternal Embryonic Leucine Zipper Kinase (MELK) as a Novel Mediator and Biomarker of Radioresistance in Human Breast Cancer in another window
Includes: Supplementary data