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Journal Articles

Phase Ib Dose Expansion and Translational Analyses of Olaparib in Combination with Capivasertib in Recurrent Endometrial, Triple-Negative Breast, and Ovarian Cancer

Clin Cancer Res (2021) 27 (23): 6354–6365.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-1656

Published: 01 December 2021

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Includes: Supplementary data

Journal Articles

Abstract PO049: Compartment-specific profiling for evaluation of disrupted signaling in early stage, low-grade endometrial cancer

Qian Zhang, Xiaoping Su, Joseph Celestino, Ying Yuan, Samuel C. Mok, Karen H. Lu, Melinda S. Yates

Clin Cancer Res (2021) 27 (3_Supplement): PO049.

DOI: https://doi.org/10.1158/1557-3265.ENDOMET20-PO049

Published: 01 February 2021

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Journal Articles

Abstract PO015: The impact of the tumor immune microenvironment on response to pembrolizumab in patients with microsatellite instability-high endometrial cancer

Jeffrey A. How, Minghao Dao, Elizabeth Euscher, Melinda Yates, Weiyi Peng, Shrina D. Patel, Karen H. Lu, Patrick Hwu, Linghua Wang, Amir A. Jazaeri

Clin Cancer Res (2021) 27 (3_Supplement): PO015.

DOI: https://doi.org/10.1158/1557-3265.ENDOMET20-PO015

Published: 01 February 2021

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Journal Articles

Abstract PO011: Spatial immune cell and transcriptome profiling uncover differential cellular and molecular signatures in primary and metastatic tumor sites in patients with advanced uterine serous cancer

Li Zhang, Angela Rynne-Vidal, Karen H. Lu, Samuel C. Mok

Clin Cancer Res (2021) 27 (3_Supplement): PO011.

DOI: https://doi.org/10.1158/1557-3265.ENDOMET20-PO011

Published: 01 February 2021

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Journal Articles

Abstract IA11: Women at high risk for ovarian cancer: Novel strategies for identification and prevention

Karen H. Lu

Clin Cancer Res (2020) 26 (13_Supplement): IA11.

DOI: https://doi.org/10.1158/1557-3265.OVCA19-IA11

Published: 01 July 2020

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Journal Articles

Abstract B43: A serum protein biomarker signature for the detection of early stages of ovarian cancer

Amy P. Skubitz, Kristin L. Boylan, Timothy K. Starr, Xuan Pu, Qing Cao, Kate Geschwind, Robert C. Bast, Jr., Karen H. Lu, Joseph Celestino, Ashley J. Petersen

Clin Cancer Res (2020) 26 (13_Supplement): B43.

DOI: https://doi.org/10.1158/1557-3265.OVCA19-B43

Published: 01 July 2020

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Journal Articles

Everolimus, Letrozole, and Metformin in Women with Advanced or Recurrent Endometrioid Endometrial Cancer: A Multi-Center, Single Arm, Phase II Study

Pamela T. Soliman, Shannon N. Westin, David A. Iglesias, Bryan M. Fellman, Ying Yuan, Qian Zhang, Melinda S. Yates, Russell R. Broaddus, Brian M. Slomovitz, Karen H. Lu, Robert L. Coleman

Clin Cancer Res (2020) 26 (3): 581–587.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-0471

Published: 03 February 2020

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Includes: Supplementary data

Journal Articles

Abstract AP08: DEVELOPMENT OF A MULTI-PROTEIN CLASSIFIER FOR OVARIAN CANCER DETECTION BY SIMULTANEOUS MEASUREMENT OF 92 SERUM PROTEINS ON PROSEEK MULTIPLEX ONCOLOGY II PLATES

Amy P.N. Skubitz, Kristin L.M. Boylan, Kate Geschwind, Qing Cao, Timothy K. Starr, Melissa A. Geller, Joseph Celestino, Robert C. Bast, Jr., Karen H. Lu, Joseph S. Koopmeiners

Clin Cancer Res (2019) 25 (22_Supplement): AP08.

DOI: https://doi.org/10.1158/1557-3265.OVCASYMP18-AP08

Published: 15 November 2019

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Journal Articles

Abstract B20: Simultaneous measurement of 92 serum protein biomarkers for the development of a multiprotein classifier for ovarian cancer detection

Amy P.N. Skubitz, Kristin L.M. Boylan, Kate Geschwind, Qing Cao, Timothy K. Starr, Melissa A. Geller, Robert C. Bast, Jr., Karen H. Lu, Joseph S. Koopmeiners

Clin Cancer Res (2018) 24 (15_Supplement): B20.

DOI: https://doi.org/10.1158/1557-3265.OVCA17-B20

Published: 01 August 2018

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Journal Articles

Elevation of TP53 Autoantibody Before CA125 in Preclinical Invasive Epithelial Ovarian Cancer

Wei-Lei Yang, Aleksandra Gentry-Maharaj, Archana Simmons, Andy Ryan, Evangelia Ourania Fourkala, Zhen Lu, Keith A. Baggerly, Yang Zhao, Karen H. Lu, David Bowtell, Ian Jacobs, Steven J. Skates, Wei-Wu He, Usha Menon, Robert C. Bast, Jr

Clin Cancer Res (2017) 23 (19): 5912–5922.

DOI: https://doi.org/10.1158/1078-0432.CCR-17-0284

Published: 01 October 2017

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Includes: Supplementary data

Journal Articles

Immune Microenvironment in Microsatellite-Instable Endometrial Cancers: Hereditary or Sporadic Origin Matters

Janelle B. Pakish, Qian Zhang, Zhongyuan Chen, Han Liang, Gary B. Chisholm, Ying Yuan, Samuel C. Mok, Russell R. Broaddus, Karen H. Lu, Melinda S. Yates

Clin Cancer Res (2017) 23 (15): 4473–4481.

DOI: https://doi.org/10.1158/1078-0432.CCR-16-2655

Published: 01 August 2017

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Includes: Supplementary data

Journal Articles

Early Detection of Ovarian Cancer using the Risk of Ovarian Cancer Algorithm with Frequent CA125 Testing in Women at Increased Familial Risk – Combined Results from Two Screening Trials

Clin Cancer Res (2017) 23 (14): 3628–3637.

DOI: https://doi.org/10.1158/1078-0432.CCR-15-2750

Published: 13 July 2017

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Includes: Supplementary data

Journal Articles

Abstract B73: Human omental-derived adipose stem cells: Modulator of ovarian cancer proliferation, migration and chemoresistance

Aleksandra Nowicka, Travis Solley, Frank C. Marini, Hadley J. Sharp, Russell R. Broaddus, Kolonin G. Mikhail, Samuel C. Mok, Wendy A. Woodward, Karen H. Lu, Ann H. Klopp

Clin Cancer Res (2013) 19 (19_Supplement): B73.

DOI: https://doi.org/10.1158/1078-0432.OVCA13-B73

Published: 13 May 2014

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Journal Articles

Loss of Tuberous Sclerosis Complex-2 Function and Activation of Mammalian Target of Rapamycin Signaling in Endometrial Carcinoma

Karen H. Lu, Weiguo Wu, Bhuvanesh Dave, Brian M. Slomovitz, Thomas W. Burke, Mark F. Munsell, Russell R. Broaddus, Cheryl Lyn Walker

Clin Cancer Res (2008) 14 (9): 2543–2550.

DOI: https://doi.org/10.1158/1078-0432.CCR-07-0321

Published: 01 May 2008

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Includes: Supplementary data

Journal Articles

Progress in Chemoprevention Drug Development: The Promise of Molecular Biomarkers for Prevention of Intraepithelial Neoplasia and Cancer—A Plan to Move Forward

Clin Cancer Res (2006) 12 (12): 3661–3697.

DOI: https://doi.org/10.1158/1078-0432.CCR-06-1104

Published: 15 June 2006

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Journal Articles

Patterns of Gene Expression in Different Histotypes of Epithelial Ovarian Cancer Correlate with Those in Normal Fallopian Tube, Endometrium, and Colon

Rebecca T. Marquez, Keith A. Baggerly, Andrea P. Patterson, Jinsong Liu, Russell Broaddus, Michael Frumovitz, Edward N. Atkinson, David I. Smith, Lynn Hartmann, David Fishman, Andrew Berchuck, Regina Whitaker, David M. Gershenson, Gordon B. Mills, Robert C. Bast, Jr., Karen H. Lu

Clin Cancer Res (2005) 11 (17): 6116–6126.

DOI: https://doi.org/10.1158/1078-0432.CCR-04-2509

Published: 06 September 2005

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Journal Articles

Methylation and Messenger RNA Expression of p15^INK4b but Not p16^INK4a Are Independent Risk Factors for Ovarian Cancer

Zhensheng Liu, Li-E Wang, Luo Wang, Karen H. Lu, Gordon B. Mills, Melissa L. Bondy, Qingyi Wei

Clin Cancer Res (2005) 11 (13): 4968–4976.

DOI: https://doi.org/10.1158/1078-0432.CCR-04-2293

Published: 06 July 2005

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Journal Articles

Gene Expression Profiles Predict Early Relapse in Ovarian Cancer after Platinum-Paclitaxel Chemotherapy

Lynn C. Hartmann, Karen H. Lu, Gerald P. Linette, William A. Cliby, Kimberly R. Kalli, David Gershenson, Robert C. Bast, James Stec, Natalia Iartchouk, David I. Smith, Jeffrey S. Ross, Sebastian Hoersch, Viji Shridhar, James Lillie, Scott H. Kaufmann, Edwin A. Clark, Andrew I. Damokosh

Clin Cancer Res (2005) 11 (6): 2149–2155.

DOI: https://doi.org/10.1158/1078-0432.CCR-04-1673

Published: 23 March 2005

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Journal Articles

Expression of the Tumor Suppressor Gene ARHI in Epithelial Ovarian Cancer Is Associated with Increased Expression of p21^WAF1/CIP1 and Prolonged Progression-Free Survival

Daniel G. Rosen, Lin Wang, Ajay N. Jain, Karen H. Lu, Robert Z. Luo, Yinhua Yu, Jinsong Liu, Robert C. Bast, Jr.

Clin Cancer Res (2004) 10 (19): 6559–6566.

DOI: https://doi.org/10.1158/1078-0432.CCR-04-0698

Published: 08 October 2004

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Journal Articles

Selection of Potential Markers for Epithelial Ovarian Cancer with Gene Expression Arrays and Recursive Descent Partition Analysis

Karen H. Lu, Andrea P. Patterson, Lin Wang, Rebecca T. Marquez, Edward N. Atkinson, Keith A. Baggerly, Lance R. Ramoth, Daniel G. Rosen, Jinsong Liu, Ingegerd Hellstrom, David Smith, Lynn Hartmann, David Fishman, Andrew Berchuck, Rosemarie Schmandt, Regina Whitaker, David M. Gershenson, Gordon B. Mills, Robert C. Bast, Jr

Clin Cancer Res (2004) 10 (10): 3291–3300.

DOI: https://doi.org/10.1158/1078-0432.CCR-03-0409

Published: 24 May 2004

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NARROW

Phase Ib Dose Expansion and Translational Analyses of Olaparib in Combination with Capivasertib in Recurrent Endometrial, Triple-Negative Breast, and Ovarian Cancer

Abstract PO049: Compartment-specific profiling for evaluation of disrupted signaling in early stage, low-grade endometrial cancer

Abstract PO015: The impact of the tumor immune microenvironment on response to pembrolizumab in patients with microsatellite instability-high endometrial cancer

Abstract PO011: Spatial immune cell and transcriptome profiling uncover differential cellular and molecular signatures in primary and metastatic tumor sites in patients with advanced uterine serous cancer

Abstract IA11: Women at high risk for ovarian cancer: Novel strategies for identification and prevention

Abstract B43: A serum protein biomarker signature for the detection of early stages of ovarian cancer

Everolimus, Letrozole, and Metformin in Women with Advanced or Recurrent Endometrioid Endometrial Cancer: A Multi-Center, Single Arm, Phase II Study

Abstract AP08: DEVELOPMENT OF A MULTI-PROTEIN CLASSIFIER FOR OVARIAN CANCER DETECTION BY SIMULTANEOUS MEASUREMENT OF 92 SERUM PROTEINS ON PROSEEK MULTIPLEX ONCOLOGY II PLATES

Abstract B20: Simultaneous measurement of 92 serum protein biomarkers for the development of a multiprotein classifier for ovarian cancer detection

Elevation of TP53 Autoantibody Before CA125 in Preclinical Invasive Epithelial Ovarian Cancer

Immune Microenvironment in Microsatellite-Instable Endometrial Cancers: Hereditary or Sporadic Origin Matters

Early Detection of Ovarian Cancer using the Risk of Ovarian Cancer Algorithm with Frequent CA125 Testing in Women at Increased Familial Risk – Combined Results from Two Screening Trials

Abstract B73: Human omental-derived adipose stem cells: Modulator of ovarian cancer proliferation, migration and chemoresistance

Loss of Tuberous Sclerosis Complex-2 Function and Activation of Mammalian Target of Rapamycin Signaling in Endometrial Carcinoma

Progress in Chemoprevention Drug Development: The Promise of Molecular Biomarkers for Prevention of Intraepithelial Neoplasia and Cancer—A Plan to Move Forward

Patterns of Gene Expression in Different Histotypes of Epithelial Ovarian Cancer Correlate with Those in Normal Fallopian Tube, Endometrium, and Colon

Methylation and Messenger RNA Expression of p15^INK4b but Not p16^INK4a Are Independent Risk Factors for Ovarian Cancer

Gene Expression Profiles Predict Early Relapse in Ovarian Cancer after Platinum-Paclitaxel Chemotherapy

Expression of the Tumor Suppressor Gene ARHI in Epithelial Ovarian Cancer Is Associated with Increased Expression of p21^WAF1/CIP1 and Prolonged Progression-Free Survival

Selection of Potential Markers for Epithelial Ovarian Cancer with Gene Expression Arrays and Recursive Descent Partition Analysis

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