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Journal Articles

Optimizing Cervical Target Volume in Patients with Nasopharyngeal Cancer Based On Nodal Drainage Distance

Yang Liu, Wenbin Yan, Chaosu Hu, Xiaodong Huang, Kai Wang, Yuan Qu, Xuesong Chen, Runye Wu, Ye Zhang, Jianghu Zhang, Jingwei Luo, Yexiong Li, Jingbo Wang, Junlin Yi
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (9): 1801–1810.
https://doi.org/10.1158/1078-0432.CCR-23-3274
Published: 01 May 2024
View article titled, Optimizing Cervical Target Volume in Patients with Nasopharyngeal Cancer Based On Nodal Drainage Distance
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Includes: Supplementary data
Journal Articles

A Novel Third-generation EGFR Tyrosine Kinase Inhibitor Abivertinib for EGFR T790M-mutant Non–Small Cell Lung Cancer: a Multicenter Phase I/II Study

Qing Zhou, Lin Wu, Pei Hu, Tongtong An, Jianying Zhou, Li Zhang, Xiao-Qing Liu, Feng Luo, Xin Zheng, Ying Cheng, Nong Yang, Junling Li, Jifeng Feng, Baohui Han, Yong Song, Kai Wang, Li Zhang, Jian Fang, Hong Zhao, Yongqian Shu, Xiao-Yan Lin, Zhihong Chen, Bin Gan, Wan-Hong Xu, Wei Tang, Xiaoying Zhang, Jin-Ji Yang, Xiao Xu, Yi-Long Wu
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (6): 1127–1135.
https://doi.org/10.1158/1078-0432.CCR-21-2595
Published: 15 March 2022
View article titled, A Novel Third-generation EGFR Tyrosine Kinase Inhibitor Abivertinib for EGFR T790M-mutant Non–Small Cell Lung Cancer: a Multicenter Phase I/II Study
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Includes: Supplementary data
Journal Articles

Genomic Landscape and Tumor Mutational Burden Determination of Circulating Tumor DNA in Over 5,000 Chinese Patients with Lung Cancer

Jie Shi, Zhiyu Wang, Junping Zhang, Yaping Xu, Xiao Xiao, Xiangming Quan, Ying Bai, Xia Yang, Zongjuan Ming, Xiaojin Guo, Huijing Feng, Xiaoling Yang, Xiaofei Zhuang, Fei Han, Kai Wang, Yonglei Shi, Yu Lei, Jun Bai, Shuanying Yang
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (22): 6184–6196.
https://doi.org/10.1158/1078-0432.CCR-21-1537
Published: 15 November 2021
View article titled, Genomic Landscape and Tumor Mutational Burden Determination of Circulating Tumor DNA in Over 5,000 Chinese Patients with Lung Cancer
Open the PDF for Genomic Landscape and Tumor Mutational Burden Determination of Circulating Tumor DNA in Over 5,000 Chinese Patients with Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Alterations in DNA Damage Repair Genes in Primary Liver Cancer

Jianzhen Lin, Junping Shi, Honglin Guo, Xu Yang, Yan Jiang, Junyu Long, Yi Bai, Dongxu Wang, Xiaobo Yang, Xueshuai Wan, Lei Zhang, Jie Pan, Ke Hu, Mei Guan, Li Huo, Xinting Sang, Kai Wang, Haitao Zhao
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (15): 4701–4711.
https://doi.org/10.1158/1078-0432.CCR-19-0127
Published: 01 August 2019
View article titled, Alterations in DNA Damage Repair Genes in Primary Liver Cancer
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Includes: Supplementary data
Journal Articles

Correction: RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors

Sherene Loi, Sathana Dushyanthen, Paul A. Beavis, Roberto Salgado, Carsten Denkert, Peter Savas, Susan Combs, David L. Rimm, Jennifer M. Giltnane, Monica V. Estrada, Violeta Sánchez, Melinda E. Sanders, Rebecca S. Cook, Mark A. Pilkinton, Simon A. Mallal, Kai Wang, Vincent A. Miller, Phil J. Stephens, Roman Yelensky, Franco D. Doimi, Henry Gómez, Sergey V. Ryzhov, Phillip K. Darcy, Carlos L. Arteaga, Justin M. Balko
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (4): 1437.
https://doi.org/10.1158/1078-0432.CCR-18-4264
Published: 15 February 2019
View article titled, Correction: RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors
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Journal Articles

Profiling of 149 Salivary Duct Carcinomas, Carcinoma Ex Pleomorphic Adenomas, and Adenocarcinomas, Not Otherwise Specified Reveals Actionable Genomic Alterations

Kai Wang, Jeffery S. Russell, Jessica D. McDermott, Julia A. Elvin, Depinder Khaira, Adrienne Johnson, Timothy A. Jennings, Siraj M. Ali, Molly Murray, Carrie Marshall, Dwight S. Oldham, Donna Washburn, Stuart J. Wong, Juliann Chmielecki, Roman Yelensky, Doron Lipson, Vincent A. Miller, Philip J. Stephens, Hilary S. Serracino, Jeffrey S. Ross, Daniel W. Bowles
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (24): 6061–6068.
https://doi.org/10.1158/1078-0432.CCR-15-2568
Published: 15 December 2016
View article titled, Profiling of 149 Salivary Duct Carcinomas, Carcinoma Ex Pleomorphic Adenomas, and Adenocarcinomas, Not Otherwise Specified Reveals Actionable Genomic Alterations
Open the PDF for Profiling of 149 Salivary Duct Carcinomas, Carcinoma Ex Pleomorphic Adenomas, and Adenocarcinomas, Not Otherwise Specified Reveals Actionable Genomic Alterations in another window
Includes: Supplementary data
Journal Articles

Oncogenic ALK Fusion in Rare and Aggressive Subtype of Colorectal Adenocarcinoma as a Potential Therapeutic Target

Evgeny Yakirevich, Murray B. Resnick, Shamlal Mangray, Michael Wheeler, Cynthia L. Jackson, Kara A. Lombardo, Jeeyun Lee, Kyoung-Mee Kim, Anthony J. Gill, Kai Wang, Kyle Gowen, James Sun, Vincent A. Miller, Philip J. Stephens, Siraj M. Ali, Jeffrey S. Ross, Howard Safran
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (15): 3831–3840.
https://doi.org/10.1158/1078-0432.CCR-15-3000
Published: 31 July 2016
View article titled, Oncogenic <em>ALK</em> Fusion in Rare and Aggressive Subtype of Colorectal Adenocarcinoma as a Potential Therapeutic Target
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Includes: Supplementary data
Journal Articles

Comprehensive Genomic Profiling Identifies Frequent Drug-Sensitive EGFR Exon 19 Deletions in NSCLC not Identified by Prior Molecular Testing

Alexa B. Schrock, Garrett M. Frampton, Dana Herndon, Joel R. Greenbowe, Kai Wang, Doron Lipson, Roman Yelensky, Zachary R. Chalmers, Juliann Chmielecki, Julia A. Elvin, Mira Wollner, Addie Dvir, Lior Soussan -Gutman, Rodolfo Bordoni, Nir Peled, Fadi Braiteh, Luis Raez, Rachel Erlich, Sai-Hong Ignatius Ou, Mohamed Mohamed, Jeffrey S. Ross, Philip J. Stephens, Siraj M. Ali, Vincent A. Miller
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (13): 3281–3285.
https://doi.org/10.1158/1078-0432.CCR-15-1668
Published: 30 June 2016
View article titled, Comprehensive Genomic Profiling Identifies Frequent Drug-Sensitive EGFR Exon 19 Deletions in NSCLC not Identified by Prior Molecular Testing
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Journal Articles

RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors

Sherene Loi, Sathana Dushyanthen, Paul A. Beavis, Roberto Salgado, Carsten Denkert, Peter Savas, Susan Combs, David L. Rimm, Jennifer M. Giltnane, Monica V. Estrada, Violeta Sánchez, Melinda E. Sanders, Rebecca S. Cook, Mark A. Pilkinton, Simon A. Mallal, Kai Wang, Vincent A. Miller, Phil J. Stephens, Roman Yelensky, Franco D. Doimi, Henry Gómez, Sergey V. Ryzhov, Phillip K. Darcy, Carlos L. Arteaga, Justin M. Balko
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (6): 1499–1509.
https://doi.org/10.1158/1078-0432.CCR-15-1125
Published: 14 March 2016
View article titled, RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors
Open the PDF for RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors in another window
Includes: Supplementary data
Journal Articles

Abstract B06: Distinct genomic profiles and targetable alterations revealed by FoundationOne® Heme in hematolymphoid malignancies in adolescents and young adults.

Kai Wang, Deborah Morosini, Roman Yelensky, Doron Lipson, Juliann Chmielecki, Siraj M. Ali, Jeffrey S. Ross, Phil Stephens, Vincent A. Miller
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (17_Supplement): B06.
https://doi.org/10.1158/1557-3265.HEMMAL14-B06
Published: 19 August 2015
View article titled, Abstract B06: Distinct genomic profiles and targetable alterations revealed by FoundationOne® Heme in hematolymphoid malignancies in adolescents and young adults.
Journal Articles

PEST Domain Mutations in Notch Receptors Comprise an Oncogenic Driver Segment in Triple-Negative Breast Cancer Sensitive to a γ-Secretase Inhibitor

Kai Wang, Qin Zhang, Danan Li, Keith Ching, Cathy Zhang, Xianxian Zheng, Mark Ozeck, Stephanie Shi, Xiaorong Li, Hui Wang, Paul Rejto, James Christensen, Peter Olson
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2015) 21 (6): 1487–1496.
https://doi.org/10.1158/1078-0432.CCR-14-1348
Published: 12 March 2015
View article titled, PEST Domain Mutations in Notch Receptors Comprise an Oncogenic Driver Segment in Triple-Negative Breast Cancer Sensitive to a γ-Secretase Inhibitor
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Includes: Supplementary data
Journal Articles

A High Frequency of Activating Extracellular Domain ERBB2 (HER2) Mutation in Micropapillary Urothelial Carcinoma

Jeffrey S. Ross, Kai Wang, Laurie M. Gay, Rami N. Al-Rohil, Tipu Nazeer, Christine E. Sheehan, Timothy A. Jennings, Geoff A. Otto, Amy Donahue, Jie He, Gary Palmer, Siraj Ali, Michelle Nahas, Geneva Young, Elaine LaBrecque, Garrett Frampton, Rachel Erlich, John A. Curran, Kristina Brennan, Sean R. Downing, Roman Yelensky, Doron Lipson, Matthew Hawryluk, Vincent A. Miller, Philip J. Stephens
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2014) 20 (1): 68–75.
https://doi.org/10.1158/1078-0432.CCR-13-1992
Published: 05 January 2014
View article titled, A High Frequency of Activating Extracellular Domain <em>ERBB2</em> (<em>HER2</em>) Mutation in Micropapillary Urothelial Carcinoma
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Includes: Supplementary data
Journal Articles

Relapsed Classic E-Cadherin (CDH1)–Mutated Invasive Lobular Breast Cancer Shows a High Frequency of HER2 (ERBB2) Gene Mutations

Jeffrey S. Ross, Kai Wang, Christine E. Sheehan, Ann B. Boguniewicz, Geoff Otto, Sean R. Downing, James Sun, Jie He, John A. Curran, Siraj Ali, Roman Yelensky, Doron Lipson, Gary Palmer, Vincent A. Miller, Philip J. Stephens
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2013) 19 (10): 2668–2676.
https://doi.org/10.1158/1078-0432.CCR-13-0295
Published: 12 May 2013
View article titled, Relapsed Classic E-Cadherin (<em>CDH1</em>)–Mutated Invasive Lobular Breast Cancer Shows a High Frequency of <em>HER2</em> (<em>ERBB2</em>) Gene Mutations
Open the PDF for Relapsed Classic E-Cadherin (<em>CDH1</em>)–Mutated Invasive Lobular Breast Cancer Shows a High Frequency of <em>HER2</em> (<em>ERBB2</em>) Gene Mutations in another window
Includes: Supplementary data