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Jun Yu
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Journal Articles

Improved Assessment of Response Status in Patients with Pancreatic Cancer Treated with Neoadjuvant Therapy using Somatic Mutations and Liquid Biopsy Analysis

Lingdi Yin, Ning Pu, Elizabeth Thompson, Yi Miao, Christopher Wolfgang, Jun Yu
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (3): 740–748.
https://doi.org/10.1158/1078-0432.CCR-20-1746
Published: 01 February 2021
View article titled, Improved Assessment of Response Status in Patients with Pancreatic Cancer Treated with Neoadjuvant Therapy using Somatic Mutations and Liquid Biopsy Analysis
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Includes: Supplementary data
Journal Articles

The Influence of Immune Heterogeneity on the Effectiveness of Immune Checkpoint Inhibitors in Multifocal Hepatocellular Carcinomas

Manling Huang, Minghui He, Yu Guo, Heping Li, Shunli Shen, Yubin Xie, Xiaoxing Li, Han Xiao, Lujing Fang, Dongming Li, Baogang Peng, Lijian Liang, Jun Yu, Ming Kuang, Lixia Xu, Sui Peng
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (18): 4947–4957.
https://doi.org/10.1158/1078-0432.CCR-19-3840
Published: 15 September 2020
View article titled, The Influence of Immune Heterogeneity on the Effectiveness of Immune Checkpoint Inhibitors in Multifocal Hepatocellular Carcinomas
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Includes: Supplementary data
Journal Articles

MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer

Shiyan Wang, Junzhe Huang, Chuangen Li, Liuyang Zhao, Chi Chun Wong, Jianning Zhai, Yunfei Zhou, Wen Deng, Yong Zeng, Shanshan Gao, Yanquan Zhang, Guoping Wang, Xin Yuan Guan, Hong Wei, Sunny H. Wong, Housheng H. He, Jerry W. Shay, Jun Yu
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (3): 746–757.
https://doi.org/10.1158/1078-0432.CCR-19-1611
Published: 03 February 2020
View article titled, MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer
Open the PDF for MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer in another window
Includes: Multimedia, Supplementary data
Journal Articles

Circulating Tumor DNA as a Clinical Test in Resected Pancreatic Cancer

Vincent P. Groot, Stacy Mosier, Ammar A. Javed, Jonathan A. Teinor, Georgios Gemenetzis, Ding Ding, Lisa M. Haley, Jun Yu, Richard A. Burkhart, Alina Hasanain, Marija Debeljak, Hirohiko Kamiyama, Amol Narang, Daniel A. Laheru, Lei Zheng, Ming-Tseh Lin, Christopher D. Gocke, Elliot K. Fishman, Ralph H. Hruban, Michael G. Goggins, I. Quintus Molenaar, John L. Cameron, Matthew J. Weiss, Victor E. Velculescu, Jin He, Christopher L. Wolfgang, James R. Eshleman
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (16): 4973–4984.
https://doi.org/10.1158/1078-0432.CCR-19-0197
Published: 15 August 2019
View article titled, Circulating Tumor DNA as a Clinical Test in Resected Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

C8orf76 Promotes Gastric Tumorigenicity and Metastasis by Directly Inducing lncRNA DUSP5P1 and Associates with Patient Outcomes

Xiaohong Wang, Qiaoyi Liang, Lianhai Zhang, Hongyan Gou, Ziyu Li, Huarong Chen, Yujuan Dong, Jiafu Ji, Jun Yu
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (10): 3128–3140.
https://doi.org/10.1158/1078-0432.CCR-18-2804
Published: 15 May 2019
View article titled, C8orf76 Promotes Gastric Tumorigenicity and Metastasis by Directly Inducing lncRNA DUSP5P1 and Associates with Patient Outcomes
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Includes: Supplementary data
Journal Articles

Pancreatic Juice Mutation Concentrations Can Help Predict the Grade of Dysplasia in Patients Undergoing Pancreatic Surveillance

Masaya Suenaga, Jun Yu, Koji Shindo, Koji Tamura, Jose Alejandro Almario, Christopher Zaykoski, P. Dane Witmer, Shahriar Fesharakizadeh, Michael Borges, Anne-Marie Lennon, Eun-Ji Shin, Marcia Irene Canto, Michael Goggins
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (12): 2963–2974.
https://doi.org/10.1158/1078-0432.CCR-17-2463
Published: 14 June 2018
View article titled, Pancreatic Juice Mutation Concentrations Can Help Predict the Grade of Dysplasia in Patients Undergoing Pancreatic Surveillance
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Includes: Supplementary data
Journal Articles

Predicting the Grade of Dysplasia of Pancreatic Cystic Neoplasms Using Cyst Fluid DNA Methylation Markers

Tatsuo Hata, Marco Dal Molin, Seung-Mo Hong, Koji Tamura, Masaya Suenaga, Jun Yu, Hiraku Sedogawa, Matthew J. Weiss, Christopher L. Wolfgang, Anne Marie Lennon, Ralph H. Hruban, Michael G. Goggins
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (14): 3935–3944.
https://doi.org/10.1158/1078-0432.CCR-16-2244
Published: 13 July 2017
View article titled, Predicting the Grade of Dysplasia of Pancreatic Cystic Neoplasms Using Cyst Fluid DNA Methylation Markers
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Includes: Supplementary data
Journal Articles

Fecal Bacteria Act as Novel Biomarkers for Noninvasive Diagnosis of Colorectal Cancer

Qiaoyi Liang, Jonathan Chiu, Yingxuan Chen, Yanqin Huang, Akira Higashimori, Jingyuan Fang, Hassan Brim, Hassan Ashktorab, Siew Chien Ng, Simon Siu Man Ng, Shu Zheng, Francis Ka Leung Chan, Joseph Jao Yiu Sung, Jun Yu
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (8): 2061–2070.
https://doi.org/10.1158/1078-0432.CCR-16-1599
Published: 13 April 2017
View article titled, Fecal Bacteria Act as Novel Biomarkers for Noninvasive Diagnosis of Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Cyst Fluid Telomerase Activity Predicts the Histologic Grade of Cystic Neoplasms of the Pancreas

Tatsuo Hata, Marco Dal Molin, Masaya Suenaga, Jun Yu, Meredith Pittman, Matthew Weiss, Marcia I. Canto, Christopher Wolfgang, Anne Marie Lennon, Ralph H. Hruban, Michael Goggins
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (20): 5141–5151.
https://doi.org/10.1158/1078-0432.CCR-16-0311
Published: 13 October 2016
View article titled, Cyst Fluid Telomerase Activity Predicts the Histologic Grade of Cystic Neoplasms of the Pancreas
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Includes: Supplementary data
Journal Articles

Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma

Curtis R. Pickering, Jane H. Zhou, J. Jack Lee, Jennifer A. Drummond, S. Andrew Peng, Rami E. Saade, Kenneth Y. Tsai, Jonathan L. Curry, Michael T. Tetzlaff, Stephen Y. Lai, Jun Yu, Donna M. Muzny, Harshavardhan Doddapaneni, Eve Shinbrot, Kyle R. Covington, Jianhua Zhang, Sahil Seth, Carlos Caulin, Gary L. Clayman, Adel K. El-Naggar, Richard A. Gibbs, Randal S. Weber, Jeffrey N. Myers, David A. Wheeler, Mitchell J. Frederick
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (24): 6582–6592.
https://doi.org/10.1158/1078-0432.CCR-14-1768
Published: 14 December 2014
View article titled, Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Identification of microRNA-135b in Stool as a Potential Noninvasive Biomarker for Colorectal Cancer and Adenoma

Chung Wah Wu, Siew Chien Ng, Yujuan Dong, Linwei Tian, Simon Siu Man Ng, Wing Wa Leung, Wai Tak Law, Tung On Yau, Francis Ka Leung Chan, Joseph Jao Yiu Sung, Jun Yu
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2014) 20 (11): 2994–3002.
https://doi.org/10.1158/1078-0432.CCR-13-1750
Published: 29 May 2014
View article titled, Identification of microRNA-135b in Stool as a Potential Noninvasive Biomarker for Colorectal Cancer and Adenoma
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Includes: Supplementary data
Journal Articles

Serum miR-1290 as a Marker of Pancreatic Cancer—Response

Ang Li, Jun Yu, Haeryoung Kim, Christopher L. Wolfgang, Marcia Irene Canto, Ralph H. Hruban, Michael Goggins
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (18): 5252–5253.
https://doi.org/10.1158/1078-0432.CCR-13-1899
Published: 16 September 2013
View article titled, Serum miR-1290 as a Marker of Pancreatic Cancer—Response
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Journal Articles

MicroRNA Array Analysis Finds Elevated Serum miR-1290 Accurately Distinguishes Patients with Low-Stage Pancreatic Cancer from Healthy and Disease Controls

Ang Li, Jun Yu, Haeryoung Kim, Christopher L. Wolfgang, Marcia Irene Canto, Ralph H. Hruban, Michael Goggins
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (13): 3600–3610.
https://doi.org/10.1158/1078-0432.CCR-12-3092
Published: 30 June 2013
View article titled, MicroRNA Array Analysis Finds Elevated Serum miR-1290 Accurately Distinguishes Patients with Low-Stage Pancreatic Cancer from Healthy and Disease Controls
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Includes: Supplementary data
Journal Articles

MicroRNA Alterations of Pancreatic Intraepithelial Neoplasias

Jun Yu, Ang Li, Seung-Mo Hong, Ralph H. Hruban, Michael Goggins
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (4): 981–992.
https://doi.org/10.1158/1078-0432.CCR-11-2347
Published: 14 February 2012
View article titled, MicroRNA Alterations of Pancreatic Intraepithelial Neoplasias
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Includes: Supplementary data
Journal Articles

Genome-Wide CpG Island Profiling of Intraductal Papillary Mucinous Neoplasms of the Pancreas

Seung-Mo Hong, Noriyuki Omura, Audrey Vincent, Ang Li, Spencer Knight, Jun Yu, Ralph H. Hruban, Michael Goggins
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3): 700–712.
https://doi.org/10.1158/1078-0432.CCR-11-1718
Published: 31 January 2012
View article titled, Genome-Wide CpG Island Profiling of Intraductal Papillary Mucinous Neoplasms of the Pancreas
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Includes: Supplementary data
Journal Articles

Yes-Associated Protein 1 Exhibits Oncogenic Property in Gastric Cancer and Its Nuclear Accumulation Associates with Poor Prognosis

Wei Kang, Joanna H.M. Tong, Anthony W.H. Chan, Tin-Lap Lee, Raymond W.M. Lung, Patrick P.S. Leung, Ken K.Y. So, Kaichun Wu, Daiming Fan, Jun Yu, Joseph J.Y. Sung, Ka-Fai To
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (8): 2130–2139.
https://doi.org/10.1158/1078-0432.CCR-10-2467
Published: 14 April 2011
View article titled, Yes-Associated Protein 1 Exhibits Oncogenic Property in Gastric Cancer and Its Nuclear Accumulation Associates with Poor Prognosis
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Includes: Supplementary data
Journal Articles

The EPHB6 Receptor Tyrosine Kinase Is a Metastasis Suppressor That Is Frequently Silenced by Promoter DNA Hypermethylation in Non–Small Cell Lung Cancer

Jun Yu, Etmar Bulk, Ping Ji, Antje Hascher, Moying Tang, Ralf Metzger, Alessandro Marra, Hubert Serve, Wolfgang E. Berdel, Rainer Wiewroth, Steffen Koschmieder, Carsten Müller-Tidow
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (8): 2275–2283.
https://doi.org/10.1158/1078-0432.CCR-09-2000
Published: 14 April 2010
View article titled, The EPHB6 Receptor Tyrosine Kinase Is a Metastasis Suppressor That Is Frequently Silenced by Promoter DNA Hypermethylation in Non–Small Cell Lung Cancer
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Journal Articles

WNT5A Exhibits Tumor-Suppressive Activity through Antagonizing the Wnt/β-Catenin Signaling, and Is Frequently Methylated in Colorectal Cancer

Jianming Ying, Hongyu Li, Jun Yu, Ka Man Ng, Fan Fong Poon, Sze Chuen Cesar Wong, Anthony T.C. Chan, Joseph J.Y. Sung, Qian Tao
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (1): 55–61.
https://doi.org/10.1158/1078-0432.CCR-07-1644
Published: 02 January 2008
View article titled, <em>WNT5A</em> Exhibits Tumor-Suppressive Activity through Antagonizing the Wnt/β-Catenin Signaling, and Is Frequently Methylated in Colorectal Cancer
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Journal Articles

Effects of Helicobacter pylori Eradication on Methylation Status of E-Cadherin Gene in Noncancerous Stomach

Wai K. Leung, Ellen P.S. Man, Jun Yu, Minnie Y.Y. Go, Ka-fai To, Yoshio Yamaoka, Victoria Y.Y. Cheng, Enders K.W. Ng, Joseph J.Y. Sung
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (10): 3216–3221.
https://doi.org/10.1158/1078-0432.CCR-05-2442
Published: 17 May 2006
View article titled, Effects of <em>Helicobacter pylori</em> Eradication on Methylation Status of <em>E-Cadherin</em> Gene in Noncancerous Stomach
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