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Journal Articles

Amplification of Extrachromosomal MYC Paralogs Shapes Immunosuppressive Tumor Microenvironment in Small Cell Lung Cancer

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Jingwei Zhang, Yueqi Jin, Haodong Lin, Jiaming Deng, Yan Ju, Xueyan Hu, Jianqi She, Zhijian Liang, Kongxu Dai, Mantang Qiu, Kunkun Sun, Jun Wang, Fan Yang, Jian Chen, Ence Yang, Xiao Li
Journal: Clinical Cancer Research
Clin Cancer Res OF1–OF14.
https://doi.org/10.1158/1078-0432.CCR-24-3399
Published: 13 May 2025
View articletitled, Amplification of Extrachromosomal MYC Paralogs Shapes Immunosuppressive Tumor Microenvironment in Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Determination of MYD88 and CXCR4 Mutations for Clinical Detection and Their Significance in Waldenström Macroglobulinemia

Open Access
Yuting Yan, Ying Yu, Wenjie Xiong, Jun Wang, Yao Yao, Yujiao Jia, Yanshan Huang, Yuxi Li, Tingyu Wang, Rui Lyu, Hao Sun, Haoxu Wang, Qi Wang, Wei Liu, Gang An, Weiwei Sui, Yan Xu, Wenyang Huang, Zhen Yu, Dehui Zou, Mu Hao, Zhijian Xiao, Jianxiang Wang, Lugui Qiu, Shuhua Yi
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (23): 5483–5493.
https://doi.org/10.1158/1078-0432.CCR-23-3939
Published: 02 December 2024
View articletitled, Determination of MYD88 and CXCR4 Mutations for Clinical Detection and Their Significance in Waldenström Macroglobulinemia
Open the PDF for Determination of MYD88 and CXCR4 Mutations for Clinical Detection and Their Significance in Waldenström Macroglobulinemia in another window
Includes: Supplementary data
Journal Articles

Circulating Exosomal PD-L1 at Initial Diagnosis Predicts Outcome and Survival of Patients with Osteosarcoma

Available to Purchase
Jun Wang, Wei Guo, Xiaofang Wang, Xiaodong Tang, Xin Sun, Tingting Ren
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (3): 659–666.
https://doi.org/10.1158/1078-0432.CCR-22-2682
Published: 01 February 2023
View articletitled, Circulating Exosomal PD-L1 at Initial Diagnosis Predicts Outcome and Survival of Patients with Osteosarcoma
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Includes: Supplementary data
Journal Articles

PD-L1 Crosslinking as a New Strategy of 4-1BB Agonism Immunotherapy

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Fei Shu, Salman R. Punekar, Vamsidhar Velcheti, Miguel F. Sanmamed, Jun Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (15): 3182–3184.
https://doi.org/10.1158/1078-0432.CCR-22-0541
Published: 02 August 2022
View articletitled, PD-L1 Crosslinking as a New Strategy of 4-1BB Agonism Immunotherapy
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Journal Articles

Spatial Metabolomics Identifies Distinct Tumor-Specific Subtypes in Gastric Cancer Patients

Free
Jun Wang, Thomas Kunzke, Verena M. Prade, Jian Shen, Achim Buck, Annette Feuchtinger, Ivonne Haffner, Birgit Luber, Drolaiz H.W. Liu, Rupert Langer, Florian Lordick, Na Sun, Axel Walch
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (13): 2865–2877.
https://doi.org/10.1158/1078-0432.CCR-21-4383
Published: 01 July 2022
View articletitled, Spatial Metabolomics Identifies Distinct Tumor-Specific Subtypes in Gastric Cancer Patients
Open the PDF for Spatial Metabolomics Identifies Distinct Tumor-Specific Subtypes in Gastric Cancer Patients in another window
Includes: Supplementary data
Journal Articles

Correction: Pik3ip1 Is a Negative Immune Regulator that Inhibits Antitumor T-Cell Immunity

Free
Yichen Chen, Jun Wang, Xi Wang, Xinye Li, Jingjing Song, Juan Fang, Xiangqi Liu, Tao Liu, Dikan Wang, Qunxing Li, Shuqiong Wen, Da Ma, Juan Xia, Liqun Luo, Song Guo Zheng, Jun Cui, Gucheng Zeng, Lieping Chen, Bin Cheng, Zhi Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (10): 2197.
https://doi.org/10.1158/1078-0432.CCR-22-1109
Published: 13 May 2022
View articletitled, Correction: Pik3ip1 Is a Negative Immune Regulator that Inhibits Antitumor T-Cell Immunity
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Journal Articles

Correction: Siglec-15 as an Emerging Target for Next-generation Cancer Immunotherapy

Free
Jingwei Sun, Qiao Lu, Miguel F. Sanmamed, Jun Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (13): 3804.
https://doi.org/10.1158/1078-0432.CCR-21-1637
Published: 01 July 2021
View articletitled, Correction: Siglec-15 as an Emerging Target for Next-generation Cancer Immunotherapy
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Journal Articles

Anlotinib in Locally Advanced or Metastatic Medullary Thyroid Carcinoma: A Randomized, Double-Blind Phase IIB Trial

Free
Dapeng Li, Yihebali Chi, Xiaohong Chen, Minghua Ge, Yuan Zhang, Zhuming Guo, Jun Wang, Jie Chen, Jiewu Zhang, Ying Cheng, Zhendong Li, Hui Liu, Jianwu Qin, Jingqiang Zhu, Ruochuan Cheng, Zhengang Xu, Xiangqian Zheng, Pingzhang Tang, Ming Gao
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (13): 3567–3575.
https://doi.org/10.1158/1078-0432.CCR-20-2950
Published: 01 July 2021
View articletitled, Anlotinib in Locally Advanced or Metastatic Medullary Thyroid Carcinoma: A Randomized, Double-Blind Phase IIB Trial
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Includes: Supplementary data
Journal Articles

Correction: A Virus-infected, Reprogrammed Somatic Cell–derived Tumor Cell (VIReST) Vaccination Regime can Prevent Initiation and Progression of Pancreatic Cancer

Free
Shuangshuang Lu, Zhe Zhang, Pan Du, Louisa S. Chard, Wenli Yan, Margueritte El Khouri, Zhizhong Wang, Zhongxian Zhang, Yongchao Chu, Dongling Gao, Qinxian Zhang, Lirong Zhang, Ai Nagano, Jun Wang, Claude Chelala, Jing Liu, Jiekai Chen, Pentao Liu, Yunshu Dong, Shengdian Wang, Xiaozhu Li, Jianzeng Dong, Nick R. Lemoine, Duanqing Pei, Yaohe Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (9): 2663.
https://doi.org/10.1158/1078-0432.CCR-21-0850
Published: 01 May 2021
View articletitled, Correction: A Virus-infected, Reprogrammed Somatic Cell–derived Tumor Cell (VIReST) Vaccination Regime can Prevent Initiation and Progression of Pancreatic Cancer
Open the PDF for Correction: A Virus-infected, Reprogrammed Somatic Cell–derived Tumor Cell (VIReST) Vaccination Regime can Prevent Initiation and Progression of Pancreatic Cancer in another window
Journal Articles

Development and Validation of Machine Learning–based Model for the Prediction of Malignancy in Multiple Pulmonary Nodules: Analysis from Multicentric Cohorts

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Kezhong Chen, Yuntao Nie, Samina Park, Kai Zhang, Yangming Zhang, Yuan Liu, Bengang Hui, Lixin Zhou, Xun Wang, Qingyi Qi, Hao Li, Guannan Kang, Yuqing Huang, Yingtai Chen, Jiabao Liu, Jian Cui, Mingru Li, In Kyu Park, Chang Hyun Kang, Haifeng Shen, Yingshun Yang, Tian Guan, Yaxiao Zhang, Fan Yang, Young Tae Kim, Jun Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (8): 2255–2265.
https://doi.org/10.1158/1078-0432.CCR-20-4007
Published: 15 April 2021
View articletitled, Development and Validation of Machine Learning–based Model for the Prediction of Malignancy in Multiple Pulmonary Nodules: Analysis from Multicentric Cohorts
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Includes: Supplementary data
Journal Articles

Siglec-15 as an Emerging Target for Next-generation Cancer Immunotherapy

Available to Purchase
Jingwei Sun, Qiao Lu, Miguel F. Sanmamed, Jun Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (3): 680–688.
https://doi.org/10.1158/1078-0432.CCR-19-2925
Published: 01 February 2021
View articletitled, Siglec-15 as an Emerging Target for Next-generation Cancer Immunotherapy
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Journal Articles

A Virus-Infected, Reprogrammed Somatic Cell–Derived Tumor Cell (VIReST) Vaccination Regime Can Prevent Initiation and Progression of Pancreatic Cancer

Free
Shuangshuang Lu, Zhe Zhang, Pan Du, Louisa S. Chard, Wenli Yan, Margueritte El Khouri, Zhizhong Wang, Zhongxian Zhang, Yongchao Chu, Dongling Gao, Qinxian Zhang, Lirong Zhang, Ai Nagano, Jun Wang, Claude Chelala, Jing Liu, Jiekai Chen, Pentao Liu, Yunshu Dong, Shengdian Wang, Xiaozhu Li, Jianzeng Dong, Nick R. Lemoine, Duanqing Pei, Yaohe Wang
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (2): 465–476.
https://doi.org/10.1158/1078-0432.CCR-19-1395
Published: 15 January 2020
View articletitled, A Virus-Infected, Reprogrammed Somatic Cell–Derived Tumor Cell (VIReST) Vaccination Regime Can Prevent Initiation and Progression of Pancreatic Cancer
Open the PDF for A Virus-Infected, Reprogrammed Somatic Cell–Derived Tumor Cell (VIReST) Vaccination Regime Can Prevent Initiation and Progression of Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Perioperative Dynamic Changes in Circulating Tumor DNA in Patients with Lung Cancer (DYNAMIC)

Free
Kezhong Chen, Heng Zhao, Yanbin Shi, Fan Yang, Lien Tu Wang, Guannan Kang, Yuntao Nie, Jun Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (23): 7058–7067.
https://doi.org/10.1158/1078-0432.CCR-19-1213
Published: 02 December 2019
View articletitled, Perioperative Dynamic Changes in Circulating Tumor DNA in Patients with Lung Cancer (DYNAMIC)
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Includes: Supplementary data
Journal Articles

A Tumor-Localized Approach to Bypass Anti-4-1BB Immuno-Toxicity

Free
Tina Tianjiao Su, Xiaobin Gao, Jun Wang
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (19): 5732–5734.
https://doi.org/10.1158/1078-0432.CCR-19-1799
Published: 01 October 2019
View articletitled, A Tumor-Localized Approach to Bypass Anti-4-1BB Immuno-Toxicity
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Journal Articles

Pik3ip1 Is a Negative Immune Regulator that Inhibits Antitumor T-Cell Immunity

Free
Yichen Chen, Jun Wang, Xi Wang, Xinye Li, Jingjing Song, Juan Fang, Xiangqi Liu, Tao Liu, Dikan Wang, Qunxing Li, Shuqiong Wen, Da Ma, Juan Xia, Liqun Luo, Song Guo Zheng, Jun Cui, Gucheng Zeng, Lieping Chen, Bin Cheng, Zhi Wang
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (20): 6180–6194.
https://doi.org/10.1158/1078-0432.CCR-18-4134
Published: 01 October 2019
View articletitled, Pik3ip1 Is a Negative Immune Regulator that Inhibits Antitumor T-Cell Immunity
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Includes: Supplementary data
Journal Articles

Expression Analysis and Significance of PD-1, LAG-3, and TIM-3 in Human Non–Small Cell Lung Cancer Using Spatially Resolved and Multiparametric Single-Cell Analysis

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Ila Datar, Miguel F. Sanmamed, Jun Wang, Brian S. Henick, Jungmin Choi, Ti Badri, Weilai Dong, Nikita Mani, Maria Toki, Luis D. Mejías, Maria D. Lozano, Jose Luis Perez-Gracia, Vamsidhar Velcheti, Matthew D. Hellmann, Justin F. Gainor, Kristen McEachern, David Jenkins, Konstantinos Syrigos, Katerina Politi, Scott Gettinger, David L. Rimm, Roy S. Herbst, Ignacio Melero, Lieping Chen, Kurt A. Schalper
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (15): 4663–4673.
https://doi.org/10.1158/1078-0432.CCR-18-4142
Published: 01 August 2019
View articletitled, Expression Analysis and Significance of PD-1, LAG-3, and TIM-3 in Human Non–Small Cell Lung Cancer Using Spatially Resolved and Multiparametric Single-Cell Analysis
Open the PDF for Expression Analysis and Significance of PD-1, LAG-3, and TIM-3 in Human Non–Small Cell Lung Cancer Using Spatially Resolved and Multiparametric Single-Cell Analysis in another window
Includes: Supplementary data
Journal Articles

Targeting Androgen Receptor Activation Function-1 with EPI to Overcome Resistance Mechanisms in Castration-Resistant Prostate Cancer

Free
Yu Chi Yang, Carmen Adriana Banuelos, Nasrin R. Mawji, Jun Wang, Minoru Kato, Simon Haile, Iain J. McEwan, Stephen Plymate, Marianne D. Sadar
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (17): 4466–4477.
https://doi.org/10.1158/1078-0432.CCR-15-2901
Published: 31 August 2016
View articletitled, Targeting Androgen Receptor Activation Function-1 with EPI to Overcome Resistance Mechanisms in Castration-Resistant Prostate Cancer
Open the PDF for Targeting Androgen Receptor Activation Function-1 with EPI to Overcome Resistance Mechanisms in Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Cotargeting Androgen Receptor Splice Variants and mTOR Signaling Pathway for the Treatment of Castration-Resistant Prostate Cancer

Free
Minoru Kato, Carmen A. Banuelos, Yusuke Imamura, Jacky K. Leung, Daniel P. Caley, Jun Wang, Nasrin R. Mawji, Marianne D. Sadar
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (11): 2744–2754.
https://doi.org/10.1158/1078-0432.CCR-15-2119
Published: 31 May 2016
View articletitled, Cotargeting Androgen Receptor Splice Variants and mTOR Signaling Pathway for the Treatment of Castration-Resistant Prostate Cancer
Open the PDF for Cotargeting Androgen Receptor Splice Variants and mTOR Signaling Pathway for the Treatment of Castration-Resistant Prostate Cancer in another window
Journal Articles

Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing

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Marina Parry, Matthew J.J. Rose-Zerilli, Viktor Ljungström, Jane Gibson, Jun Wang, Renata Walewska, Helen Parker, Anton Parker, Zadie Davis, Anne Gardiner, Neil McIver-Brown, Christina Kalpadakis, Aliki Xochelli, Achilles Anagnostopoulos, Claudia Fazi, David Gonzalez de Castro, Claire Dearden, Guy Pratt, Richard Rosenquist, Margaret Ashton-Key, Francesco Forconi, Andrew Collins, Paolo Ghia, Estella Matutes, Gerassimos Pangalis, Kostas Stamatopoulos, David Oscier, Jonathan C. Strefford
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (18): 4174–4183.
https://doi.org/10.1158/1078-0432.CCR-14-2759
Published: 14 September 2015
View articletitled, Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing
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Includes: Supplementary data
Journal Articles

Reciprocal Interactions between Tumor-Associated Macrophages and CD44-Positive Cancer Cells via Osteopontin/CD44 Promote Tumorigenicity in Colorectal Cancer

Free
Guanhua Rao, Hongyi Wang, Baowei Li, Li Huang, Danfeng Xue, Xiaohui Wang, Haijing Jin, Jun Wang, Yushan Zhu, Youyong Lu, Lei Du, Quan Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (4): 785–797.
https://doi.org/10.1158/1078-0432.CCR-12-2788
Published: 14 February 2013
View articletitled, Reciprocal Interactions between Tumor-Associated Macrophages and CD44-Positive Cancer Cells via Osteopontin/CD44 Promote Tumorigenicity in Colorectal Cancer
Open the PDF for Reciprocal Interactions between Tumor-Associated Macrophages and CD44-Positive Cancer Cells via Osteopontin/CD44 Promote Tumorigenicity in Colorectal Cancer in another window
Includes: Supplementary data