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Journal Articles

Abstract PR010: Exploratory analysis of tumor tertiary lymphoid structures using a novel artificial intelligence–based approach in patients with muscle-invasive urothelial carcinoma from the CheckMate 274 trial

Johannes Alfred Witjes, Matthew D. Galsky, Jürgen E. Gschwend, Dean F. Bajorin, Matthew I. Milowsky, Gautam Jha, Roger Li, Jun Li, Vanessa Matos-Cruz, Scott Ely, George Lee, Vipul Baxi, Joshua Zhang, Saurabh Gupta, Justin M. David
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (10_Supplement): PR010.
https://doi.org/10.1158/1557-3265.BLADDER24-PR010
Published: 17 May 2024
View article titled, Abstract PR010: Exploratory analysis of tumor tertiary lymphoid structures using a novel artificial intelligence–based approach in patients with muscle-invasive urothelial carcinoma from the CheckMate 274 trial
Journal Articles

Infiltrative Vessel Co-optive Growth Pattern Induced by IQGAP3 Overexpression Promotes Microvascular Invasion in Hepatocellular Carcinoma

Miaoling Tang, Shuxia Zhang, Meisongzhu Yang, Rongni Feng, Jinbin Lin, Xiaohong Chen, Yingru Xu, Ruyuan Yu, Xinyi Liao, Ziwen Li, Xincheng Li, Man Li, Qiliang Zhang, Suwen Chen, Wanying Qian, Yuanji Liu, Libing Song, Jun Li
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (10): 2206–2224.
https://doi.org/10.1158/1078-0432.CCR-23-2933
Published: 15 May 2024
View article titled, Infiltrative Vessel Co-optive Growth Pattern Induced by IQGAP3 Overexpression Promotes Microvascular Invasion in Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma

Andrew W. Hahn, Ashley V. Menk, Dayana B. Rivadeneira, Ryan C. Augustin, Mingchu Xu, Jun Li, Xiaogang Wu, Aditya K. Mishra, Tuba N. Gide, Camelia Quek, Yan Zang, Christine N. Spencer, Alexander M. Menzies, Carrie R. Daniel, Courtney W. Hudgens, Theodore Nowicki, Lauren E. Haydu, M.A. Wadud Khan, Vancheswaran Gopalakrishnan, Elizabeth M. Burton, Jared Malke, Julie M. Simon, Chantale Bernatchez, Nagireddy Putluri, Scott E. Woodman, Y.N. Vashisht Gopal, Renato Guerrieri, Grant M. Fischer, Jian Wang, Khalida M. Wani, John F. Thompson, Jeffrey E. Lee, Patrick Hwu, Nadim Ajami, Jeffrey E. Gershenwald, Georgina V. Long, Richard A. Scolyer, Michael T. Tetzlaff, Alexander J. Lazar, Dirk Schadendorf, Jennifer A. Wargo, John M. Kirkwood, Ralph J. DeBerardinis, Han Liang, Andrew Futreal, Jianhua Zhang, James S. Wilmott, Weiyi Peng, Michael A. Davies, Greg M. Delgoffe, Yana G. Najjar, Jennifer L. McQuade
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (1): 154–164.
https://doi.org/10.1158/1078-0432.CCR-22-2661
Published: 04 January 2023
View article titled, Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma
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Includes: Supplementary data
Journal Articles

Correction: Sphingosine Kinase-1 Enhances Resistance to Apoptosis through Activation of PI3K/Akt/NFκB Pathway in Human Non–small Cell Lung Cancer

Libing Song, Huaping Xiong, Jun Li, Wenting Liao, Lan Wang, Jueheng Wu, Mengfeng Li
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (8): 1740.
https://doi.org/10.1158/1078-0432.CCR-22-0506
Published: 14 April 2022
View article titled, Correction: Sphingosine Kinase-1 Enhances Resistance to Apoptosis through Activation of PI3K/Akt/NFκB Pathway in Human Non–small Cell Lung Cancer
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Journal Articles

Molecular Imaging of Prostate Cancer Targeting CD46 Using ImmunoPET

Sinan Wang, Jun Li, Jun Hua, Yang Su, Denis R. Beckford-Vera, Walter Zhao, Mayuri Jayaraman, Tony L. Huynh, Ning Zhao, Yung-hua Wang, Yangjie Huang, Fujun Qin, Sui Shen, Daniel Gioeli, Robert Dreicer, Renuka Sriram, Emily A. Egusa, Jonathan Chou, Felix Y. Feng, Rahul Aggarwal, Michael J. Evans, Youngho Seo, Bin Liu, Robert R. Flavell, Jiang He
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (5): 1305–1315.
https://doi.org/10.1158/1078-0432.CCR-20-3310
Published: 01 March 2021
View article titled, Molecular Imaging of Prostate Cancer Targeting CD46 Using ImmunoPET
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Includes: Supplementary data
Journal Articles

TSPO-targeted PET and Optical Probes for the Detection and Localization of Premalignant and Malignant Pancreatic Lesions

Allison S. Cohen, Jun Li, Matthew R. Hight, Eliot McKinley, Allie Fu, Adria Payne, Yang Liu, Dawei Zhang, Qing Xie, Mingfeng Bai, Gregory D. Ayers, Mohammed Noor Tantawy, Jarrod A. Smith, Frank Revetta, M. Kay Washington, Chanjuan Shi, Nipun Merchant, H. Charles Manning
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (22): 5914–5925.
https://doi.org/10.1158/1078-0432.CCR-20-1214
Published: 13 November 2020
View article titled, TSPO-targeted PET and Optical Probes for the Detection and Localization of Premalignant and Malignant Pancreatic Lesions
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Includes: Multimedia, Supplementary data
Journal Articles

Evolution of Genomic and T-cell Repertoire Heterogeneity of Malignant Pleural Mesothelioma Under Dasatinib Treatment

Runzhe Chen, Won-Chul Lee, Junya Fujimoto, Jun Li, Xin Hu, Reza Mehran, David Rice, Stephen G. Swisher, Boris Sepesi, Hai T. Tran, Chi-Wan Chow, Latasha D. Little, Curtis Gumbs, Cara Haymaker, John V. Heymach, Ignacio I. Wistuba, J. Jack Lee, P. Andrew Futreal, Jianhua Zhang, Alexandre Reuben, Anne S. Tsao, Jianjun Zhang
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (20): 5477–5486.
https://doi.org/10.1158/1078-0432.CCR-20-1767
Published: 15 October 2020
View article titled, Evolution of Genomic and T-cell Repertoire Heterogeneity of Malignant Pleural Mesothelioma Under Dasatinib Treatment
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Includes: Supplementary data
Journal Articles

Submucosal Saline Injection Followed by Endoscopic Ultrasound versus Endoscopic Ultrasound Only for Distinguishing between T1a and T1b Esophageal Cancer

Long-Jun He, Chuanbo Xie, Zi-Xian Wang, Yin Li, Yi-Tai Xiao, Xiao-Yan Gao, Hong-Bo Shan, Lin-Na Luo, Li-Ming Chen, Guang-Yu Luo, Ping Yang, Shuo-Chun Zeng, Guo-Liang Xu, Jian-Jun Li
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (2): 384–390.
https://doi.org/10.1158/1078-0432.CCR-19-1722
Published: 15 January 2020
View article titled, Submucosal Saline Injection Followed by Endoscopic Ultrasound versus Endoscopic Ultrasound Only for Distinguishing between T1a and T1b Esophageal Cancer
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Includes: Supplementary data
Journal Articles

Targeting Purinergic Receptor P2Y2 Prevents the Growth of Pancreatic Ductal Adenocarcinoma by Inhibiting Cancer Cell Glycolysis

Li-Peng Hu, Xiao-Xin Zhang, Shu-Heng Jiang, Ling-Ye Tao, Qing Li, Li-Li Zhu, Ming-Wei Yang, Yan-Miao Huo, Yong-Sheng Jiang, Guang-Ang Tian, Xiao-Yan Cao, Yan-Li Zhang, Qin Yang, Xiao-Mei Yang, Ya-Hui Wang, Jun Li, Gary Guishan Xiao, Yong-Wei Sun, Zhi-Gang Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (4): 1318–1330.
https://doi.org/10.1158/1078-0432.CCR-18-2297
Published: 15 February 2019
View article titled, Targeting Purinergic Receptor P2Y2 Prevents the Growth of Pancreatic Ductal Adenocarcinoma by Inhibiting Cancer Cell Glycolysis
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Includes: Supplementary data
Journal Articles

Loss of RBMS3 Confers Platinum Resistance in Epithelial Ovarian Cancer via Activation of miR-126-5p/β-catenin/CBP signaling

Geyan Wu, Lixue Cao, Jinrong Zhu, Zhanyao Tan, Miaoling Tang, Ziwen Li, Yameng Hu, Ruyuan Yu, Shuxia Zhang, Libing Song, Jun Li
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (3): 1022–1035.
https://doi.org/10.1158/1078-0432.CCR-18-2554
Published: 01 February 2019
View article titled, Loss of RBMS3 Confers Platinum Resistance in Epithelial Ovarian Cancer via Activation of miR-126-5p/β-catenin/CBP signaling
Open the PDF for Loss of RBMS3 Confers Platinum Resistance in Epithelial Ovarian Cancer via Activation of miR-126-5p/β-catenin/CBP signaling in another window
Includes: Supplementary data
Journal Articles

The Novel Bromodomain and Extraterminal Domain Inhibitor INCB054329 Induces Vulnerabilities in Myeloma Cells That Inform Rational Combination Strategies

Matthew C. Stubbs, Timothy C. Burn, Richard Sparks, Thomas Maduskuie, Sharon Diamond, Mark Rupar, Xiaoming Wen, Alla Volgina, Nina Zolotarjova, Paul Waeltz, Margaret Favata, Ravi Jalluri, Huiqing Liu, Xuesong Mike Liu, Jun Li, Robert Collins, Nikoo Falahatpisheh, Padmaja Polam, Darlise DiMatteo, Patricia Feldman, Valerie Dostalik, Pramod Thekkat, Christine Gardiner, Xin He, Yanlong Li, Maryanne Covington, Richard Wynn, Bruce Ruggeri, Swamy Yeleswaram, Chu-Biao Xue, Wenqing Yao, Andrew P. Combs, Reid Huber, Gregory Hollis, Peggy Scherle, Phillip C.C. Liu
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (1): 300–311.
https://doi.org/10.1158/1078-0432.CCR-18-0098
Published: 03 January 2019
View article titled, The Novel Bromodomain and Extraterminal Domain Inhibitor INCB054329 Induces Vulnerabilities in Myeloma Cells That Inform Rational Combination Strategies
Open the PDF for The Novel Bromodomain and Extraterminal Domain Inhibitor INCB054329 Induces Vulnerabilities in Myeloma Cells That Inform Rational Combination Strategies in another window
Includes: Supplementary data
Journal Articles

Clinical and Biologic Significance of MYC Genetic Mutations in De Novo Diffuse Large B-cell Lymphoma

Zijun Y. Xu-Monette, Qipan Deng, Ganiraju C. Manyam, Alexander Tzankov, Ling Li, Yi Xia, Xiao-xiao Wang, Dehui Zou, Carlo Visco, Karen Dybkær, Jun Li, Li Zhang, Han Liang, Santiago Montes-Moreno, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W.L. Choi, J. Han van Krieken, Jooryung Huh, Maurilio Ponzoni, Andrés J.M. Ferreri, Ben M. Parsons, Michael B. Møller, Sa A. Wang, Roberto N. Miranda, Miguel A. Piris, Jane N. Winter, L. Jeffrey Medeiros, Yong Li, Ken H. Young
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (14): 3593–3605.
https://doi.org/10.1158/1078-0432.CCR-15-2296
Published: 14 July 2016
View article titled, Clinical and Biologic Significance of <em>MYC</em> Genetic Mutations in <em>De Novo</em> Diffuse Large B-cell Lymphoma
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Includes: Supplementary data
Journal Articles

The quantitatively analysis of epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) and its correlation with response rate of EGFR tyrosine kinase inhibitors (TKI)

Jun Li, Zhao Chen, Daqiang Sun, Meilin Xu, Xun Zhang, Junpu Xu
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (19_Supplement): PR10.
https://doi.org/10.1158/DIAG-10-PR10
Published: 15 August 2014
View article titled, The quantitatively analysis of epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) and its correlation with response rate of EGFR tyrosine kinase inhibitors (TKI)
Journal Articles

Clinical Activity of Adjuvant Cytokine-Induced Killer Cell Immunotherapy in Patients with Post-Mastectomy Triple-Negative Breast Cancer

Ke Pan, Xun-Xing Guan, Yong-Qiang Li, Jing-Jing Zhao, Jian-Jun Li, Hui-Juan Qiu, De-Sheng Weng, Qi-Jing Wang, Qing Liu, Li-Xi Huang, Jia He, Shi-Ping Chen, Miao-La Ke, Yi-Xin Zeng, Jian-Chuan Xia
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (11): 3003–3011.
https://doi.org/10.1158/1078-0432.CCR-14-0082
Published: 29 May 2014
View article titled, Clinical Activity of Adjuvant Cytokine-Induced Killer Cell Immunotherapy in Patients with Post-Mastectomy Triple-Negative Breast Cancer
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Includes: Supplementary data
Journal Articles

Downregulation of miR-138 Sustains NF-κB Activation and Promotes Lipid Raft Formation in Esophageal Squamous Cell Carcinoma

Hui Gong, Libing Song, Chuyong Lin, Aibin Liu, Xi Lin, Jueheng Wu, Mengfeng Li, Jun Li
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (5): 1083–1093.
https://doi.org/10.1158/1078-0432.CCR-12-3169
Published: 03 March 2013
View article titled, Downregulation of miR-138 Sustains NF-κB Activation and Promotes Lipid Raft Formation in Esophageal Squamous Cell Carcinoma
Open the PDF for Downregulation of miR-138 Sustains NF-κB Activation and Promotes Lipid Raft Formation in Esophageal Squamous Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Overexpression of GOLPH3 Promotes Proliferation and Tumorigenicity in Breast Cancer via Suppression of the FOXO1 Transcription Factor

Zhaolei Zeng, Huanxin Lin, Xiaohui Zhao, Guanglin Liu, Xi Wang, Ruihua Xu, Kun Chen, Jun Li, Libing Song
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (15): 4059–4069.
https://doi.org/10.1158/1078-0432.CCR-11-3156
Published: 30 July 2012
View article titled, Overexpression of GOLPH3 Promotes Proliferation and Tumorigenicity in Breast Cancer via Suppression of the FOXO1 Transcription Factor
Open the PDF for Overexpression of GOLPH3 Promotes Proliferation and Tumorigenicity in Breast Cancer via Suppression of the FOXO1 Transcription Factor in another window
Includes: Supplementary data
Journal Articles

Knockdown of FLOT1 Impairs Cell Proliferation and Tumorigenicity in Breast Cancer through Upregulation of FOXO3a

Chuyong Lin, Zhiqiang Wu, Xi Lin, Chunping Yu, Tingting Shi, Yong Zeng, Xi Wang, Jun Li, Libing Song
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (10): 3089–3099.
https://doi.org/10.1158/1078-0432.CCR-10-3068
Published: 15 May 2011
View article titled, Knockdown of FLOT1 Impairs Cell Proliferation and Tumorigenicity in Breast Cancer through Upregulation of FOXO3a
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Includes: Supplementary data
Journal Articles

Sphingosine Kinase-1 Enhances Resistance to Apoptosis through Activation of PI3K/Akt/NF-κB Pathway in Human Non–Small Cell Lung Cancer

Libing Song, Huaping Xiong, Jun Li, Wenting Liao, Lan Wang, Jueheng Wu, Mengfeng Li
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (7): 1839–1849.
https://doi.org/10.1158/1078-0432.CCR-10-0720
Published: 01 April 2011
View article titled, Sphingosine Kinase-1 Enhances Resistance to Apoptosis through Activation of PI3K/Akt/NF-κB Pathway in Human Non–Small Cell Lung Cancer
Open the PDF for Sphingosine Kinase-1 Enhances Resistance to Apoptosis through Activation of PI3K/Akt/NF-κB Pathway in Human Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Mechanisms of Inactivation of PTCH1 Gene in Nevoid Basal Cell Carcinoma Syndrome: Modification of the Two-Hit Hypothesis

Shuang Pan, Qing Dong, Li-Sha Sun, Tie-Jun Li
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (2): 442–450.
https://doi.org/10.1158/1078-0432.CCR-09-2574
Published: 14 January 2010
View article titled, Mechanisms of Inactivation of <em>PTCH1</em> Gene in Nevoid Basal Cell Carcinoma Syndrome: Modification of the Two-Hit Hypothesis
Open the PDF for Mechanisms of Inactivation of <em>PTCH1</em> Gene in Nevoid Basal Cell Carcinoma Syndrome: Modification of the Two-Hit Hypothesis in another window
Journal Articles

Combined Inhibition of Janus Kinase 1/2 for the Treatment of JAK2V617F-Driven Neoplasms: Selective Effects on Mutant Cells and Improvements in Measures of Disease Severity

Phillip C.C. Liu, Eian Caulder, Jun Li, Paul Waeltz, Alex Margulis, Richard Wynn, Mary Becker-Pasha, Yanlong Li, Erin Crowgey, Gregory Hollis, Patrick Haley, Richard B. Sparks, Andrew P. Combs, James D. Rodgers, Timothy C. Burn, Kris Vaddi, Jordan S. Fridman
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (22): 6891–6900.
https://doi.org/10.1158/1078-0432.CCR-09-1298
Published: 11 November 2009
View article titled, Combined Inhibition of Janus Kinase 1/2 for the Treatment of JAK2V617F-Driven Neoplasms: Selective Effects on Mutant Cells and Improvements in Measures of Disease Severity
Open the PDF for Combined Inhibition of Janus Kinase 1/2 for the Treatment of JAK2V617F-Driven Neoplasms: Selective Effects on Mutant Cells and Improvements in Measures of Disease Severity in another window
Includes: Supplementary data