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Julien Mazieres
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Journal Articles

Comprehensive Genome Profiling in Patients With Metastatic Non–Small Cell Lung Cancer: The Precision Medicine Phase II Randomized SAFIR02-Lung/IFCT 1301 Trial

Fabrice Barlesi, Pascale Tomasini, Maryam Karimi, Stefan Michiels, Judith Raimbourg, Catherine Daniel, Henri Janicot, Anne Madroszyk, Clarisse Audigier-Valette, Elisabeth Quoix, Julien Mazieres, Denis Moro-Sibilot, Eric Dansin, Olivier Molinier, Hugues Morel, Eric Pichon, Alexis Cortot, Josiane Otto, François Chomy, Pierre-Jean Souquet, Nicolas Cloarec, Etienne Giroux-Leprieur, Ivan Bieche, Ludovic Lacroix, Sandrine Boyault, Valery Attignon, Isabelle Soubeyran, Alain Morel, Alicia Tran-Dien, Alexandra Jacquet, Filippo Gustavo Dall'Olio, Marta Jimenez, Jean-Charles Soria, Benjamin Besse
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (18): 4018–4026.
https://doi.org/10.1158/1078-0432.CCR-22-0371
Published: 15 September 2022
View article titled, Comprehensive Genome Profiling in Patients With Metastatic Non–Small Cell Lung Cancer: The Precision Medicine Phase II Randomized SAFIR02-Lung/IFCT 1301 Trial
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Includes: Supplementary data
Journal Articles

Tepotinib Efficacy and Safety in Patients with MET Exon 14 Skipping NSCLC: Outcomes in Patient Subgroups from the VISION Study with Relevance for Clinical Practice

Xiuning Le, Hiroshi Sakai, Enriqueta Felip, Remi Veillon, Marina Chiara Garassino, Jo Raskin, Alexis B. Cortot, Santiago Viteri, Julien Mazieres, Egbert F. Smit, Michael Thomas, Wade T. Iams, Byoung Chul Cho, Hye Ryun Kim, James Chih-Hsin Yang, Yuh-Min Chen, Jyoti D. Patel, Christine M. Bestvina, Keunchil Park, Frank Griesinger, Melissa Johnson, Maya Gottfried, Christian Britschgi, John Heymach, Elif Sikoglu, Karin Berghoff, Karl-Maria Schumacher, Rolf Bruns, Gordon Otto, Paul K. Paik
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (6): 1117–1126.
https://doi.org/10.1158/1078-0432.CCR-21-2733
Published: 15 March 2022
View article titled, Tepotinib Efficacy and Safety in Patients with <em>MET</em> Exon 14 Skipping NSCLC: Outcomes in Patient Subgroups from the VISION Study with Relevance for Clinical Practice
Open the PDF for Tepotinib Efficacy and Safety in Patients with <em>MET</em> Exon 14 Skipping NSCLC: Outcomes in Patient Subgroups from the VISION Study with Relevance for Clinical Practice in another window
Includes: Supplementary data
Journal Articles

Circulating Tumor DNA Genomics Reveal Potential Mechanisms of Resistance to BRAF-Targeted Therapies in Patients with BRAF-Mutant Metastatic Non–Small Cell Lung Cancer

Sandra Ortiz-Cuaran, Laura Mezquita, Aurélie Swalduz, Mihalea Aldea, Julien Mazieres, Camille Leonce, Cecile Jovelet, Anne Pradines, Virginie Avrillon, Washington R. Chumbi Flores, Ludovic Lacroix, Yohann Loriot, Virginie Westeel, Maud Ngo-Camus, Claire Tissot, Christine Raynaud, Radj Gervais, Etienne Brain, Isabelle Monnet, Etienne Giroux Leprieur, Caroline Caramella, Celine Mahier-Aït Oukhatar, Natalie Hoog-Labouret, Frank de Kievit, Karen Howarth, Clive Morris, Emma Green, Luc Friboulet, Sylvie Chabaud, Jean-François Guichou, Maurice Perol, Benjamin Besse, Jean-Yves Blay, Pierre Saintigny, David Planchard
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (23): 6242–6253.
https://doi.org/10.1158/1078-0432.CCR-20-1037
Published: 01 December 2020
View article titled, Circulating Tumor DNA Genomics Reveal Potential Mechanisms of Resistance to BRAF-Targeted Therapies in Patients with <em>BRAF</em>-Mutant Metastatic Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Randomized Phase II Trial Evaluating Treatment with EGFR-TKI Associated with Antiestrogen in Women with Nonsquamous Advanced-Stage NSCLC: IFCT-1003 LADIE Trial

Julien Mazieres, Fabrice Barlesi, Isabelle Rouquette, Olivier Molinier, Benjamin Besse, Isabelle Monnet, Clarisse Audigier-Valette, Anne-Claire Toffart, Patrick Aldo Renault, Séverine Fraboulet, Sandrine Hiret, Bertrand Mennecier, Didier Debieuvre, Virginie Westeel, Philippe Masson, Anne Madroszyk-Flandin, Eric Pichon, Alexis B. Cortot, Elodie Amour, Franck Morin, Gérard Zalcman, Denis Moro-Sibilot, Pierre-Jean Souquet
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (13): 3172–3181.
https://doi.org/10.1158/1078-0432.CCR-19-3056
Published: 01 July 2020
View article titled, Randomized Phase II Trial Evaluating Treatment with EGFR-TKI Associated with Antiestrogen in Women with Nonsquamous Advanced-Stage NSCLC: IFCT-1003 LADIE Trial
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Journal Articles

Health-Related Quality of Life Impact from Adding Bevacizumab to Cisplatin-Pemetrexed in Malignant Pleural Mesothelioma in the MAPS IFCT-GFPC-0701 Phase III Trial

Guillaume Eberst, Amélie Anota, Arnaud Scherpereel, Julien Mazieres, Jacques Margery, Laurent Greillier, Clarisse Audigier-Valette, Denis Moro-Sibilot, Olivier Molinier, Hervé Léna, Frédéric Rivière, Isabelle Monnet, Valérie Gounant, Henri Janicot, Radj Gervais, Chrystelle Locher, Emilie Charton, Franck Morin, Gérard Zalcman, Virginie Westeel
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (19): 5759–5765.
https://doi.org/10.1158/1078-0432.CCR-18-2860
Published: 01 October 2019
View article titled, Health-Related Quality of Life Impact from Adding Bevacizumab to Cisplatin-Pemetrexed in Malignant Pleural Mesothelioma in the MAPS IFCT-GFPC-0701 Phase III Trial
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Includes: Supplementary data
Journal Articles

Ultra-sensitive EGFRT790M Detection as an Independent Prognostic Marker for Lung Cancer Patients Harboring EGFRdel19 Mutations and Treated with First-generation TKIs

Julie A. Vendrell, Julien Mazieres, Romain Senal, Isabelle Rouquette, Xavier Quantin, Jean-Louis Pujol, Benoit Roch, Abdelali Bouidioua, Sylvain Godreuil, Etienne Coyaud, Pierre Brousset, Jérôme Solassol
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (14): 4280–4289.
https://doi.org/10.1158/1078-0432.CCR-18-2683
Published: 15 July 2019
View article titled, Ultra-sensitive <em>EGFR</em><sup>T790M</sup> Detection as an Independent Prognostic Marker for Lung Cancer Patients Harboring <em>EGFR</em><sup>del19</sup> Mutations and Treated with First-generation TKIs
Open the PDF for Ultra-sensitive <em>EGFR</em><sup>T790M</sup> Detection as an Independent Prognostic Marker for Lung Cancer Patients Harboring <em>EGFR</em><sup>del19</sup> Mutations and Treated with First-generation TKIs in another window
Includes: Supplementary data
Journal Articles

Randomized, Placebo-Controlled, Phase II Study of Veliparib in Combination with Carboplatin and Paclitaxel for Advanced/Metastatic Non–Small Cell Lung Cancer

Suresh S. Ramalingam, Normand Blais, Julien Mazieres, Martin Reck, C. Michael Jones, Erzsebet Juhasz, Laszlo Urban, Sergey Orlov, Fabrice Barlesi, Ebenezer Kio, Ulrich Keiholz, Qin Qin, Jiang Qian, Caroline Nickner, Juliann Dziubinski, Hao Xiong, Peter Ansell, Mark McKee, Vincent Giranda, Vera Gorbunova
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (8): 1937–1944.
https://doi.org/10.1158/1078-0432.CCR-15-3069
Published: 13 April 2017
View article titled, Randomized, Placebo-Controlled, Phase II Study of Veliparib in Combination with Carboplatin and Paclitaxel for Advanced/Metastatic Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Bevacizumab in Patients with Nonsquamous Non–Small Cell Lung Cancer and Asymptomatic, Untreated Brain Metastases (BRAIN): A Nonrandomized, Phase II Study

Benjamin Besse, Sylvestre Le Moulec, Julien Mazières, Hélène Senellart, Fabrice Barlesi, Christos Chouaid, Eric Dansin, Henri Bérard, Lionel Falchero, Radj Gervais, Gilles Robinet, Anne-Marie Ruppert, Roland Schott, Hervé Léna, Christelle Clément-Duchêne, Xavier Quantin, Pierre Jean Souquet, Jean Trédaniel, Denis Moro-Sibilot, Maurice Pérol, Anne-Catherine Madroszyk, Jean-Charles Soria
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2015) 21 (8): 1896–1903.
https://doi.org/10.1158/1078-0432.CCR-14-2082
Published: 14 April 2015
View article titled, Bevacizumab in Patients with Nonsquamous Non–Small Cell Lung Cancer and Asymptomatic, Untreated Brain Metastases (BRAIN): A Nonrandomized, Phase II Study
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Includes: Supplementary data
Journal Articles

RhoB Determines Tumor Aggressiveness in a Murine EGFRL858R-Induced Adenocarcinoma Model and Is a Potential Prognostic Biomarker for Lepidic Lung Cancer

Olivier Calvayrac, Anne Pradines, Isabelle Raymond-Letron, Isabelle Rouquette, Emilie Bousquet, Valérie Lauwers-Cances, Thomas Filleron, Jacques Cadranel, Michèle Beau-Faller, Anne Casanova, Julie Milia, Gilles Favre, Julien Mazières
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (24): 6541–6550.
https://doi.org/10.1158/1078-0432.CCR-14-0506
Published: 14 December 2014
View article titled, RhoB Determines Tumor Aggressiveness in a Murine EGFR<sup>L858R</sup>-Induced Adenocarcinoma Model and Is a Potential Prognostic Biomarker for Lepidic Lung Cancer
Open the PDF for RhoB Determines Tumor Aggressiveness in a Murine EGFR<sup>L858R</sup>-Induced Adenocarcinoma Model and Is a Potential Prognostic Biomarker for Lepidic Lung Cancer in another window
Includes: Supplementary data
Journal Articles

A Comparative and Integrative Approach Identifies ATPase Family, AAA Domain Containing 2 as a Likely Driver of Cell Proliferation in Lung Adenocarcinoma

Robert Fouret, Julien Laffaire, Paul Hofman, Michèle Beau-Faller, Julien Mazieres, Pierre Validire, Philippe Girard, Sophie Camilleri-Bröet, Fabien Vaylet, François Leroy-Ladurie, Jean-Charles Soria, Pierre Fouret
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (20): 5606–5616.
https://doi.org/10.1158/1078-0432.CCR-12-0505
Published: 14 October 2012
View article titled, A Comparative and Integrative Approach Identifies <em>ATPase Family, AAA Domain Containing 2</em> as a Likely Driver of Cell Proliferation in Lung Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Abstract B4: A “DNA replication stress” gene signature associated with a poor prognosis in early non-small cell lung cancer

Camille Allera-Moreau, Marie-Bernadette Delisle, Jean-Sebastien Hoffmann, Christophe Cazaux, Isabelle Rouquette, Benoit Lepage, Naima Oumouhou, Karine Gordien, Laurent Brouchet, Julien Mazieres, Philippe Pasero
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3_Supplement): B4.
https://doi.org/10.1158/1078-0432.12AACRIASLC-B4
Published: 01 February 2012
View article titled, Abstract B4: A “DNA replication stress” gene signature associated with a poor prognosis in early non-small cell lung cancer
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Journal Articles

Abstract B17: The small RhoGTPase RhoB as a new potential marker of EGFR-TKI resistance

Claire Marty, Gilles Favre, Julien Mazieres
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3_Supplement): B17.
https://doi.org/10.1158/1078-0432.12AACRIASLC-B17
Published: 01 February 2012
View article titled, Abstract B17: The small RhoGTPase RhoB as a new potential marker of EGFR-TKI resistance
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Journal Articles

Loss of RhoB Expression in Human Lung Cancer Progression

Julien Mazieres, Teresita Antonia, Ghislaine Daste, Carlos Muro-Cacho, Delphine Berchery, Vanessa Tillement, Anne Pradines, Said Sebti, Gilles Favre
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (8): 2742–2750.
https://doi.org/10.1158/1078-0432.CCR-03-0149
Published: 20 April 2004
View article titled, Loss of RhoB Expression in Human Lung Cancer Progression
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