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Julian Adams
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Journal Articles

Abstract PR2: Therapeutic intervention targeting a Hedgehog-dependent barrier to drug delivery in pancreatic cancer

Kenneth P. Olive, Michael Jacobetz, Aarthi Gopinathan, Mae Goldgraben, Heather Ireland, Stefanie Reichelt, William J. Howat, Nigel Whitebread, Karen McGovern, Julian Adams, Christine Iacobuzio-Donahue, John Griffiths, David Tuveson
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (14_Supplement): PR2.
https://doi.org/10.1158/1078-0432.TCMUSA10-PR2
Published: 02 February 2016
View article titled, Abstract PR2: Therapeutic intervention targeting a Hedgehog-dependent barrier to drug delivery in pancreatic cancer
Journal Articles

PK/PD relationships: Following the target of bortezomib (Velcade)

Julian Adams
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (15_Supplement): CN02-01.
Published: 15 August 2014
View article titled, PK/PD relationships: Following the target of bortezomib (Velcade)
Journal Articles

Small Molecule Inhibitors of IκB Kinase Are Selectively Toxic for Subgroups of Diffuse Large B-Cell Lymphoma Defined by Gene Expression Profiling

Lloyd T. Lam, R. Eric Davis, Jackie Pierce, Michael Hepperle, Yajun Xu, Maria Hottelet, Yuhua Nong, Danyi Wen, Julian Adams, Lenny Dang, Louis M. Staudt
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (1): 28–40.
https://doi.org/10.1158/1078-0432.28.11.1
Published: 21 January 2005
View article titled, Small Molecule Inhibitors of IκB Kinase Are Selectively Toxic for Subgroups of Diffuse Large B-Cell Lymphoma Defined by Gene Expression Profiling
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Journal Articles

Drug Interactions between the Proteasome Inhibitor Bortezomib and Cytotoxic Chemotherapy, Tumor Necrosis Factor (TNF) α, and TNF-Related Apoptosis-Inducing Ligand in Prostate Cancer

Jiabin An, Yi-Ping Sun, Julian Adams, Myrna Fisher, Arie Belldegrun, Matthew B. Rettig
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (12): 4537–4545.
Published: 10 October 2003
View article titled, Drug Interactions between the Proteasome Inhibitor Bortezomib and Cytotoxic Chemotherapy, Tumor Necrosis Factor (TNF) α, and TNF-Related Apoptosis-Inducing Ligand in Prostate Cancer
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Journal Articles

The Proteasome Inhibitor PS-341 Markedly Enhances Sensitivity of Multiple Myeloma Tumor Cells to Chemotherapeutic Agents

Mark H. Ma, Hank H. Yang, Kimberly Parker, Steven Manyak, Jeffrey M. Friedman, Cibby Altamirano, Zhi-qun Wu, Mitesh J. Borad, Malka Frantzen, Evanthia Roussos, Jason Neeser, Amy Mikail, Julian Adams, Nelida Sjak-Shie, Robert A. Vescio, James R. Berenson
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (3): 1136–1144.
Published: 01 March 2003
View article titled, The Proteasome Inhibitor PS-341 Markedly Enhances Sensitivity of Multiple Myeloma Tumor Cells to Chemotherapeutic Agents
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Journal Articles

Mechanisms of Proteasome Inhibitor PS-341-induced G2-M-Phase Arrest and Apoptosis in Human Non-Small Cell Lung Cancer Cell Lines

Yi-He Ling, Leonard Liebes, Jian-Dong Jiang, James F. Holland, Peter J. Elliott, Julian Adams, Franco M. Muggia, Roman Perez-Soler
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (3): 1145–1154.
Published: 01 March 2003
View article titled, Mechanisms of Proteasome Inhibitor PS-341-induced G<sub>2</sub>-M-Phase Arrest and Apoptosis in Human Non-Small Cell Lung Cancer Cell Lines
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Journal Articles

A Phase I Trial of the Novel Proteasome Inhibitor PS341 in Advanced Solid Tumor Malignancies

Carol Aghajanian, Steven Soignet, Don S. Dizon, Christine S. Pien, Julian Adams, Peter J. Elliott, Paul Sabbatini, Vincent Miller, Martee L. Hensley, Sandra Pezzulli, Christina Canales, Adil Daud, David R. Spriggs
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (8): 2505–2511.
Published: 01 August 2002
View article titled, A Phase I Trial of the Novel Proteasome Inhibitor PS341 in Advanced Solid Tumor Malignancies
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Journal Articles

Novel Proteasome Inhibitor PS-341 Inhibits Activation of Nuclear Factor-κB, Cell Survival, Tumor Growth, and Angiogenesis in Squamous Cell Carcinoma

John B. Sunwoo, Zhong Chen, Gang Dong, Ning Yeh, Caren Crowl Bancroft, Edward Sausville, Julian Adams, Peter Elliott, Carter Van Waes
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (5): 1419–1428.
Published: 01 May 2001
View article titled, Novel Proteasome Inhibitor PS-341 Inhibits Activation of Nuclear Factor-κB, Cell Survival, Tumor Growth, and Angiogenesis in Squamous Cell Carcinoma
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Journal Articles

Lack of Multicellular Drug Resistance Observed in Human Ovarian and Prostate Carcinoma Treated with the Proteasome Inhibitor PS-341

Andrea Frankel, Shan Man, Peter Elliott, Julian Adams, Robert S. Kerbel
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (9): 3719–3728.
Published: 01 September 2000
View article titled, Lack of Multicellular Drug Resistance Observed in Human Ovarian and Prostate Carcinoma Treated with the Proteasome Inhibitor PS-341
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Journal Articles

The Proteasome Inhibitor PS-341 in Cancer Therapy

Beverly A. Teicher, Gulshan Ara, Roy Herbst, Vito J. Palombella, Julian Adams
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (9): 2638–2645.
Published: 01 September 1999
View article titled, The Proteasome Inhibitor PS-341 in Cancer Therapy
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