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Joseph R. Testa
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Journal Articles

Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma

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Yinfei Tan, Eleonora Sementino, Mitchell Cheung, Suraj Peri, Craig W. Menges, Anna-Mariya Kukuyan, Ting Zhang, Vladimir Khazak, Lauren A. Fox, Eric A. Ross, Suresh Ramanathan, Suresh C. Jhanwar, Raja M. Flores, Siddharth Balachandran, Joseph R. Testa
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (4): 1200–1213.
https://doi.org/10.1158/1078-0432.CCR-18-3683
Published: 15 February 2021
View articletitled, Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma
Open the PDF for Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma in another window
Includes: Supplementary data
Journal Articles

GSK690693 Delays Tumor Onset and Progression in Genetically Defined Mouse Models Expressing Activated Akt

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Deborah A. Altomare, Lili Zhang, Jing Deng, Antonio Di Cristofano, Andres J. Klein-Szanto, Rakesh Kumar, Joseph R. Testa
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (2): 486–496.
https://doi.org/10.1158/1078-0432.CCR-09-1026
Published: 14 January 2010
View articletitled, GSK690693 Delays Tumor Onset and Progression in Genetically Defined Mouse Models Expressing Activated Akt
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Includes: Supplementary data
Journal Articles

mTOR Is a Promising Therapeutic Target Both in Cisplatin-Sensitive and Cisplatin-Resistant Clear Cell Carcinoma of the Ovary

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Seiji Mabuchi, Chiaki Kawase, Deborah A. Altomare, Kenichirou Morishige, Kenjiro Sawada, Masami Hayashi, Masahiko Tsujimoto, Mareo Yamoto, Andres J. Klein-Szanto, Russell J. Schilder, Masahide Ohmichi, Joseph R. Testa, Tadashi Kimura
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (17): 5404–5413.
https://doi.org/10.1158/1078-0432.CCR-09-0365
Published: 31 August 2009
View articletitled, mTOR Is a Promising Therapeutic Target Both in Cisplatin-Sensitive and Cisplatin-Resistant Clear Cell Carcinoma of the Ovary
Open the PDF for mTOR Is a Promising Therapeutic Target Both in Cisplatin-Sensitive and Cisplatin-Resistant Clear Cell Carcinoma of the Ovary in another window
Journal Articles

RAD001 Inhibits Human Ovarian Cancer Cell Proliferation, Enhances Cisplatin-Induced Apoptosis, and Prolongs Survival in an Ovarian Cancer Model

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Seiji Mabuchi, Deborah A. Altomare, Mitchell Cheung, Lili Zhang, Poulikos I. Poulikakos, Harvey H. Hensley, Russell J. Schilder, Robert F. Ozols, Joseph R. Testa
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (14): 4261–4270.
https://doi.org/10.1158/1078-0432.CCR-06-2770
Published: 18 July 2007
View articletitled, RAD001 Inhibits Human Ovarian Cancer Cell Proliferation, Enhances Cisplatin-Induced Apoptosis, and Prolongs Survival in an Ovarian Cancer Model
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Journal Articles

Inhibition of Inhibitor of Nuclear Factor-κB Phosphorylation Increases the Efficacy of Paclitaxel in in Vitro and in Vivo Ovarian Cancer Models

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Seiji Mabuchi, Masahide Ohmichi, Yukihiro Nishio, Tadashi Hayasaka, Akiko Kimura, Tsuyoshi Ohta, Jun Kawagoe, Kazuhiro Takahashi, Namiko Yada-Hashimoto, Hozumi Seino-Noda, Masahiro Sakata, Teiichi Motoyama, Hirohisa Kurachi, Joseph R. Testa, Keiichi Tasaka, Yuji Murata
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (22): 7645–7654.
https://doi.org/10.1158/1078-0432.CCR-04-0958
Published: 29 November 2004
View articletitled, Inhibition of Inhibitor of Nuclear Factor-κB Phosphorylation Increases the Efficacy of Paclitaxel in in Vitro and in Vivo Ovarian Cancer Models
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Journal Articles

Loss of Methylthioadenosine Phosphorylase and Elevated Ornithine Decarboxylase Is Common in Pancreatic Cancer

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Ahmad L. Subhi, Baiqing Tang, Binaifer R. Balsara, Deborah A. Altomare, Joseph R. Testa, Harry S. Cooper, John P. Hoffman, Neal J. Meropol, Warren D. Kruger
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (21): 7290–7296.
https://doi.org/10.1158/1078-0432.CCR-04-0972
Published: 08 November 2004
View articletitled, Loss of Methylthioadenosine Phosphorylase and Elevated Ornithine Decarboxylase Is Common in Pancreatic Cancer
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Journal Articles

Increased Fatty Acid Synthase is a Therapeutic Target in Mesothelioma

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Edward W. Gabrielson, Michael L. Pinn, Joseph R. Testa, Francis P. Kuhajda
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (1): 153–157.
Published: 01 January 2001
View articletitled, Increased Fatty Acid Synthase is a Therapeutic Target in Mesothelioma
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Journal Articles

The p16 Status of Tumor Cell Lines Identifies Small Molecule Inhibitors Specific for Cyclin-dependent Kinase 4

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Akihito Kubo, Kazuhiko Nakagawa, Ravi K. Varma, Nicholas K. Conrad, Jin Quan Cheng, Wen-Ching Lee, Joseph R. Testa, Bruce E. Johnson, Frederic J. Kaye, Michael J. Kelley
Journal: Clinical Cancer Research
Clin Cancer Res (1999) 5 (12): 4279–4286.
Published: 01 December 1999
View articletitled, The p16 Status of Tumor Cell Lines Identifies Small Molecule Inhibitors Specific for Cyclin-dependent Kinase 4
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