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Joseph J. Cullen
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Journal Articles

Magnetic Resonance Imaging of Iron Metabolism with T2* Mapping Predicts an Enhanced Clinical Response to Pharmacologic Ascorbate in Patients with GBM

Michael S. Petronek, Varun Monga, Kellie L. Bodeker, Michael Kwofie, Chu-Yu Lee, Kranti A. Mapuskar, Jeffrey M. Stolwijk, Amira Zaher, Brett A. Wagner, Mark C. Smith, Sandy Vollstedt, Heather Brown, Meghan L. Chandler, Amanda C. Lorack, Jared S. Wulfekuhle, Jann N. Sarkaria, Ryan T. Flynn, Jeremy D.W. Greenlee, Matthew A. Howard, Brian J. Smith, Karra A. Jones, Garry R. Buettner, Joseph J. Cullen, Joel St-Aubin, John M. Buatti, Vincent A. Magnotta, Douglas R. Spitz, Bryan G. Allen
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (2): 283–293.
https://doi.org/10.1158/1078-0432.CCR-22-3952
Published: 17 January 2024
View article titled, Magnetic Resonance Imaging of Iron Metabolism with T<sub>2</sub>* Mapping Predicts an Enhanced Clinical Response to Pharmacologic Ascorbate in Patients with GBM
Open the PDF for Magnetic Resonance Imaging of Iron Metabolism with T<sub>2</sub>* Mapping Predicts an Enhanced Clinical Response to Pharmacologic Ascorbate in Patients with GBM in another window
Includes: Supplementary data
Journal Articles

First-in-Human Phase I Clinical Trial of Pharmacologic Ascorbate Combined with Radiation and Temozolomide for Newly Diagnosed Glioblastoma

Bryan G. Allen, Kellie L. Bodeker, Mark C. Smith, Varun Monga, Sonia Sandhu, Raymond Hohl, Thomas Carlisle, Heather Brown, Nancy Hollenbeck, Sandy Vollstedt, Jeremy D. Greenlee, Matthew A. Howard, Kranti A. Mapuskar, Steven N. Seyedin, Joseph M. Caster, Karra A. Jones, Joseph J. Cullen, Daniel Berg, Brett A. Wagner, Garry R. Buettner, Mindi J. TenNapel, Brian J. Smith, Douglas R. Spitz, John M. Buatti
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (22): 6590–6597.
https://doi.org/10.1158/1078-0432.CCR-19-0594
Published: 15 November 2019
View article titled, First-in-Human Phase I Clinical Trial of Pharmacologic Ascorbate Combined with Radiation and Temozolomide for Newly Diagnosed Glioblastoma
Open the PDF for First-in-Human Phase I Clinical Trial of Pharmacologic Ascorbate Combined with Radiation and Temozolomide for Newly Diagnosed Glioblastoma in another window
Includes: Supplementary data
Journal Articles

Mechanisms of Ascorbate-Induced Cytotoxicity in Pancreatic Cancer

Juan Du, Sean M. Martin, Mark Levine, Brett A. Wagner, Garry R. Buettner, Sih-han Wang, Agshin F. Taghiyev, Changbin Du, Charles M. Knudson, Joseph J. Cullen
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (2): 509–520.
https://doi.org/10.1158/1078-0432.CCR-09-1713
Published: 14 January 2010
View article titled, Mechanisms of Ascorbate-Induced Cytotoxicity in Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Modulation of Reactive Oxygen Species in Pancreatic Cancer

Melissa L.T. Teoh, Wenqing Sun, Brian J. Smith, Larry W. Oberley, Joseph J. Cullen
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (24): 7441–7450.
https://doi.org/10.1158/1078-0432.CCR-07-0851
Published: 19 December 2007
View article titled, Modulation of Reactive Oxygen Species in Pancreatic Cancer
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Journal Articles

Treatment of Pancreatic Cancer Cells with Dicumarol Induces Cytotoxicity and Oxidative Stress

Anne Lewis, Matthew Ough, Ling Li, Marilyn M. Hinkhouse, Justine M. Ritchie, Douglas R. Spitz, Joseph J. Cullen
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (13): 4550–4558.
https://doi.org/10.1158/1078-0432.CCR-03-0667
Published: 06 July 2004
View article titled, Treatment of Pancreatic Cancer Cells with Dicumarol Induces Cytotoxicity and Oxidative Stress
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