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Josef Straub
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Journal Articles

MGMT Promoter Methylation Cutoff with Safety Margin for Selecting Glioblastoma Patients into Trials Omitting Temozolomide: A Pooled Analysis of Four Clinical Trials

Monika E. Hegi, Els Genbrugge, Thierry Gorlia, Roger Stupp, Mark R. Gilbert, Olivier L. Chinot, L. Burt Nabors, Greg Jones, Wim Van Criekinge, Josef Straub, Michael Weller
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (6): 1809–1816.
https://doi.org/10.1158/1078-0432.CCR-18-3181
Published: 15 March 2019
View article titled, <em>MGMT</em> Promoter Methylation Cutoff with Safety Margin for Selecting Glioblastoma Patients into Trials Omitting Temozolomide: A Pooled Analysis of Four Clinical Trials
Open the PDF for <em>MGMT</em> Promoter Methylation Cutoff with Safety Margin for Selecting Glioblastoma Patients into Trials Omitting Temozolomide: A Pooled Analysis of Four Clinical Trials in another window
Includes: Supplementary data
Journal Articles

Differential Effect on Bone Lesions of Targeting Integrins: Randomized Phase II Trial of Abituzumab in Patients with Metastatic Castration-Resistant Prostate Cancer

Maha Hussain, Sylvestre Le Moulec, Claude Gimmi, Rolf Bruns, Josef Straub, Kurt Miller
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (13): 3192–3200.
https://doi.org/10.1158/1078-0432.CCR-15-2512
Published: 30 June 2016
View article titled, Differential Effect on Bone Lesions of Targeting Integrins: Randomized Phase II Trial of Abituzumab in Patients with Metastatic Castration-Resistant Prostate Cancer
Open the PDF for Differential Effect on Bone Lesions of Targeting Integrins: Randomized Phase II Trial of Abituzumab in Patients with Metastatic Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Pharmacomethylomics: methylation profiling applied to drug resistance models

Josef Straub, Pauline de Graef, Geert Trooskens, Katja Bierau, Steven de Jong, Joseph W. Bigley, Ate van der Zee, Herman Spolders, Wim MR Van Criekinge
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (19_Supplement): A95.
Published: 15 August 2014
View article titled, Pharmacomethylomics: methylation profiling applied to drug resistance models
Journal Articles

Feasibility of a urine-based DNA methylation assay for early detection of bladder cancer

John Kelly, Isabelle Renard, Catherine Colette, Christophe Naome, Hubert Nicolas, Ellen Zwarthoff, Josef Straub, Wim van Criekinge, Peter Lens, Lokesh Suraparaju, Joseph Bigley, Virginia Meihaus, Katja Bierau, James DiGiuseppi, David Waltregny
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (19_Supplement): A62.
Published: 15 August 2014
View article titled, Feasibility of a urine-based DNA methylation assay for early detection of bladder cancer
Journal Articles

Feasibility of a DNA methylation assay for noninvasive CRC screening

Joost Louwagie, Linda Bosch, Ivano DiStefano, Sandra van den Bosch, Mark Opdam, Gontran Brichard, Josef Straub, Gaetan Otto, Wim van Criekinge, Madeleine Grooteclaes, Jochim Terhaar sive Droste, Beatriz Carvalho, Gerrit Meijer, Manon van Engeland, Maarten Penning, Katja Bierau
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (19_Supplement): B16.
Published: 15 August 2014
View article titled, Feasibility of a DNA methylation assay for noninvasive CRC screening
Journal Articles

Correlation between testing MGMT gene promoter methylation status of glioblastoma tissue using nested gel-based and direct real-time fluorescence-based methylation-specific PCR.

Ilse Vlassenbroeck, Stephane Califice, Annie-Claire Diserens, Eugenia Migliavacca, Josef Straub, Ivano DiStefano, Fabrice Moreau, Marie-France Hamou, Isabelle Renard, Mauro Delorenzi, Bruno Flamion, Katja Bierau, Monika Hegi
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (19_Supplement): A64.
Published: 15 August 2014
View article titled, Correlation between testing MGMT gene promoter methylation status of glioblastoma tissue using nested gel-based and direct real-time fluorescence-based methylation-specific PCR.
Journal Articles

Base5, a versatile, highly integrated high-throughput methylation profiling platform for methylation specific PCR based marker identification applied to colorectal cancer

Josef Straub, Geert Trooskens, Luc Segers, James di Guiseppi, Katja Bierau, Joost Louwagie, Herman Spolders, John Beeler, Wim Van Criekinge
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (19_Supplement): A61.
Published: 15 August 2014
View article titled, Base5, a versatile, highly integrated high-throughput methylation profiling platform for methylation specific PCR based marker identification applied to colorectal cancer