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Jonathan D. Schoenfeld
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Journal Articles

Next-Generation Sequencing–Based MSI Scoring Predicts Benefit in Mismatch Repair–Deficient Tumors Treated with Nivolumab: Follow-up on NCI-MATCH Arm Z1D

Jonathan D. Schoenfeld, Nilofer S. Azad, Jacob Gross, Li Chen, Michael J. Overman, Katrina Kao, Latifa Jackson, Donna Brunnquell, Xiangning Bu, Christina Coppola, Ping Guan, Jennifer Lee, David Sims, Rebecca Fuchs, Jason L. Weirather, Kathleen L. Pfaff, Lauren Gunasti, Srin Ranasinghe, Stanley R. Hamilton, Victoria Wang, Peter J. O’Dwyer, Catherine J. Wu, Scott J. Rodig, David R. Patton, Lyndsay Harris
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (4): 667–677.
https://doi.org/10.1158/1078-0432.CCR-24-0427
Published: 17 February 2025
View article titled, Next-Generation Sequencing–Based MSI Scoring Predicts Benefit in Mismatch Repair–Deficient Tumors Treated with Nivolumab: Follow-up on NCI-MATCH Arm Z1D
Open the PDF for Next-Generation Sequencing–Based MSI Scoring Predicts Benefit in Mismatch Repair–Deficient Tumors Treated with Nivolumab: Follow-up on NCI-MATCH Arm Z1D in another window
Includes: Supplementary data
Journal Articles

A Prospective Trial of Biomarker-Guided Surveillance for HPV-Positive Oropharynx Cancer Using Plasma Tumor Tissue–Modified Viral HPV DNA

Eleni M. Rettig, Jonathan D. Schoenfeld, Julianna Miller, Bethany Sargent, Evan Carey, Danielle N. Margalit, Kartik Sehgal, Rosh K.V. Sethi, Ravindra Uppaluri, Roy B. Tishler, Laura A. Goguen, Donald J. Annino, Edward S. Sim, Vickie Y. Jo, Kristine S. Wong, Jeffrey P. Guenette, Robert I. Haddad, Glenn J. Hanna
Journal: Clinical Cancer Research
Clin Cancer Res OF1–OF10.
https://doi.org/10.1158/1078-0432.CCR-24-3053
Published: 13 January 2025
View article titled, A Prospective Trial of Biomarker-Guided Surveillance for HPV-Positive Oropharynx Cancer Using Plasma Tumor Tissue–Modified Viral HPV DNA
Open the PDF for A Prospective Trial of Biomarker-Guided Surveillance for HPV-Positive Oropharynx Cancer Using Plasma Tumor Tissue–Modified Viral HPV DNA in another window
Includes: Supplementary data
Journal Articles

Abstract B024: Personalized tumor-informed circulating tumor (ct) DNA for advanced thyroid carcinoma

Kartik Sehgal, Theodora Pappa, Michael J. Dennis, Nicole J. Scarfo, Michelle S. Mullin, Tura Coombs, Roy B. Tishler, Danielle N. Margalit, Ravindra Uppaluri, Rosh K. Sethi, Jonathan D. Schoenfeld, Justine A. Barletta, Gerard M. Doherty, Erik K. Alexander, Laura A. Goguen, Eleni M. Rettig, Robert I. Haddad, Glenn J. Hanna
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (21_Supplement): B024.
https://doi.org/10.1158/1557-3265.LIQBIOP24-B024
Published: 13 November 2024
View article titled, Abstract B024: Personalized tumor-informed circulating tumor (ct) DNA for advanced thyroid carcinoma
Journal Articles

Personalized ctDNA for Monitoring Disease Status in Head and Neck Squamous Cell Carcinoma

Glenn J. Hanna, Michael J. Dennis, Nicole Scarfo, Michelle S. Mullin, Rosh K.V. Sethi, Kartik Sehgal, Donald J. Annino, Jr, Laura A. Goguen, Robert I. Haddad, Roy B. Tishler, Danielle N. Margalit, Ravindra Uppaluri, Jonathan D. Schoenfeld, Eleni M. Rettig
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (15): 3329–3336.
https://doi.org/10.1158/1078-0432.CCR-24-0590
Published: 01 August 2024
View article titled, Personalized ctDNA for Monitoring Disease Status in Head and Neck Squamous Cell Carcinoma
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Includes: Supplementary data
Journal Articles

Abstract PO-078: Tissue-resident memory CD8+ T cells correlate with anti-PD-1 response in head and neck cancer and expand upon cDC1 activation in tumor-draining lymph nodes to overcome PD-1 resistance

Michihisa Kono, Shin Saito, Geoff Ivison, Ayano Kondo, Aaron Mayer, Jonathan D. Schoenfeld, Ann Marie Egloff, Ravindra Uppaluri
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (18_Supplement): PO-078.
https://doi.org/10.1158/1557-3265.AACRAHNS23-PO-078
Published: 15 September 2023
View article titled, Abstract PO-078: Tissue-resident memory CD8+ T cells correlate with anti-PD-1 response in head and neck cancer and expand upon cDC1 activation in tumor-draining lymph nodes to overcome PD-1 resistance
Journal Articles

Neoadjuvant and Adjuvant Nivolumab and Lirilumab in Patients with Recurrent, Resectable Squamous Cell Carcinoma of the Head and Neck

Glenn J. Hanna, Anne O'Neill, Kee-Young Shin, Kristine Wong, Vickie Y. Jo, Charles T. Quinn, Jennifer M. Cutler, Michelle Flynn, Patrick H. Lizotte, Donald J. Annino, Jr, Laura A. Goguen, Jason I. Kass, Eleni M. Rettig, Rosh K.V. Sethi, Jochen H. Lorch, Jonathan D. Schoenfeld, Danielle N. Margalit, Roy B. Tishler, Peter C. Everett, Anupam M. Desai, Megan E. Cavanaugh, Cloud P. Paweletz, Ann Marie Egloff, Ravindra Uppaluri, Robert I. Haddad
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (3): 468–478.
https://doi.org/10.1158/1078-0432.CCR-21-2635
Published: 01 February 2022
View article titled, Neoadjuvant and Adjuvant Nivolumab and Lirilumab in Patients with Recurrent, Resectable Squamous Cell Carcinoma of the Head and Neck
Open the PDF for Neoadjuvant and Adjuvant Nivolumab and Lirilumab in Patients with Recurrent, Resectable Squamous Cell Carcinoma of the Head and Neck in another window
Includes: Supplementary data
Journal Articles

Correction: A Randomized Trial of Combined PD-L1 and CTLA-4 Inhibition with Targeted Low-dose or Hypofractionated Radiation for Patients with Metastatic Colorectal Cancer

Arta M. Monjazeb, Anita Giobbie-Hurder, Ana Lako, Emily M. Thrash, Ryan C. Brennick, Katrina Z. Kao, Claire Manuszak, Ryan D. Gentzler, Anteneh Tesfaye, Salma K. Jabbour, Olatunji B. Alese, Osama E. Rahma, James M. Cleary, Elad Sharon, Harvey J. Mamon, May Cho, Howard Streicher, Helen X. Chen, Mansoor M. Ahmed, Adrian Mariño-Enríquez, Seunghee Kim-Schulze, Sacha Gnjatic, Emanual Maverakis, Alina I. Marusina, Alexander A. Merleev, Mariano Severgnini, Kathleen L. Pfaff, James Lindsay, Jason L. Weirather, Srinika Ranasinghe, Alexander Spektor, Scott J. Rodig, F. Stephen Hodi, Jonathan D. Schoenfeld
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (17): 4940.
https://doi.org/10.1158/1078-0432.CCR-21-2698
Published: 01 September 2021
View article titled, Correction: A Randomized Trial of Combined PD-L1 and CTLA-4 Inhibition with Targeted Low-dose or Hypofractionated Radiation for Patients with Metastatic Colorectal Cancer
Open the PDF for Correction: A Randomized Trial of Combined PD-L1 and CTLA-4 Inhibition with Targeted Low-dose or Hypofractionated Radiation for Patients with Metastatic Colorectal Cancer in another window
Journal Articles

A Randomized Trial of Combined PD-L1 and CTLA-4 Inhibition with Targeted Low-Dose or Hypofractionated Radiation for Patients with Metastatic Colorectal Cancer

Arta M. Monjazeb, Anita Giobbie-Hurder, Ana Lako, Emily M. Thrash, Ryan C. Brennick, Katrina Z. Kao, Claire Manuszak, Ryan D. Gentzler, Anteneh Tesfaye, Salma K. Jabbour, Olatunji B. Alese, Osama E. Rahma, James M. Cleary, Elad Sharon, Harvey J. Mamon, May Cho, Howard Streicher, Helen X. Chen, Mansoor M. Ahmed, Adrian Mariño-Enríquez, Seunghee Kim-Schulze, Sacha Gnjatic, Emanual Maverakis, Alina I. Marusina, Alexander A. Merleev, Mariano Severgnini, Kathleen L. Pfaff, James Lindsay, Jason L. Weirather, Srinika Ranasinghe, Alexander Spektor, Scott J. Rodig, F. Stephen Hodi, Jonathan D. Schoenfeld
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (9): 2470–2480.
https://doi.org/10.1158/1078-0432.CCR-20-4632
Published: 01 May 2021
View article titled, A Randomized Trial of Combined PD-L1 and CTLA-4 Inhibition with Targeted Low-Dose or Hypofractionated Radiation for Patients with Metastatic Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Correction: Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–unrelated Head and Neck Cancer: A Multicenter, Phase II Trial

Ravindra Uppaluri, Katie M. Campbell, Ann Marie Egloff, Paul Zolkind, Zachary L. Skidmore, Brian Nussenbaum, Randal C. Paniello, Jason T. Rich, Ryan Jackson, Patrik Pipkorn, Loren S. Michel, Jessica Ley, Peter Oppelt, Gavin P. Dunn, Erica K. Barnell, Nicholas C. Spies, Tianxiang Lin, Tiantian Li, David T. Mulder, Youstina Hanna, Iulia Cirlan, Trevor J. Pugh, Tenny Mudianto, Rachel Riley, Liye Zhou, Vickie Y. Jo, Matthew D. Stachler, Glenn J. Hanna, Jason Kass, Robert Haddad, Jonathan D. Schoenfeld, Evisa Gjini, Ana Lako, Wade Thorstad, Hiram A. Gay, Mackenzie Daly, Scott J. Rodig, Ian S. Hagemann, Dorina Kallogjeri, Jay F. Piccirillo, Rebecca D. Chernock, Malachi Griffith, Obi L. Griffith, Douglas R. Adkins
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (1): 357.
https://doi.org/10.1158/1078-0432.CCR-20-4484
Published: 04 January 2021
View article titled, Correction: Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–unrelated Head and Neck Cancer: A Multicenter, Phase II Trial
Open the PDF for Correction: Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–unrelated Head and Neck Cancer: A Multicenter, Phase II Trial in another window
Journal Articles

Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial

Ravindra Uppaluri, Katie M. Campbell, Ann Marie Egloff, Paul Zolkind, Zachary L. Skidmore, Brian Nussenbaum, Randal C. Paniello, Jason T. Rich, Ryan Jackson, Patrik Pipkorn, Loren S. Michel, Jessica Ley, Peter Oppelt, Gavin P. Dunn, Erica K. Barnell, Nicholas C. Spies, Tianxiang Lin, Tiantian Li, David T. Mulder, Youstina Hanna, Iulia Cirlan, Trevor J. Pugh, Tenny Mudianto, Rachel Riley, Liye Zhou, Vickie Y. Jo, Matthew D. Stachler, Glenn J. Hanna, Jason Kass, Robert Haddad, Jonathan D. Schoenfeld, Evisa Gjini, Ana Lako, Wade Thorstad, Hiram A. Gay, Mackenzie Daly, Scott J. Rodig, Ian S. Hagemann, Dorina Kallogjeri, Jay F. Piccirillo, Rebecca D. Chernock, Malachi Griffith, Obi L. Griffith, Douglas R. Adkins
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (19): 5140–5152.
https://doi.org/10.1158/1078-0432.CCR-20-1695
Published: 01 October 2020
View article titled, Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial
Open the PDF for Neoadjuvant and Adjuvant Pembrolizumab in Resectable Locally Advanced, Human Papillomavirus–Unrelated Head and Neck Cancer: A Multicenter, Phase II Trial in another window
Includes: Supplementary data
Journal Articles

Lessons Learned from Deescalation Trials in Favorable Risk HPV-Associated Squamous Cell Head and Neck Cancer–A Perspective on Future Trial Designs

Steffen Ventz, Lorenzo Trippa, Jonathan D. Schoenfeld
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (24): 7281–7286.
https://doi.org/10.1158/1078-0432.CCR-19-0945
Published: 13 December 2019
View article titled, Lessons Learned from Deescalation Trials in Favorable Risk HPV-Associated Squamous Cell Head and Neck Cancer–A Perspective on Future Trial Designs
Open the PDF for Lessons Learned from Deescalation Trials in Favorable Risk HPV-Associated Squamous Cell Head and Neck Cancer–A Perspective on Future Trial Designs in another window
Includes: Supplementary data
Journal Articles

Incorporation of Next-Generation Sequencing into Routine Clinical Care to Direct Treatment of Head and Neck Squamous Cell Carcinoma

Nicole G. Chau, Yvonne Y. Li, Vickie Y. Jo, Guilherme Rabinowits, Jochen H. Lorch, Roy B. Tishler, Danielle N. Margalit, Jonathan D. Schoenfeld, Don J. Annino, Laura A. Goguen, Tom Thomas, Hailey Becker, Tyler Haddad, Jeffrey F. Krane, Neal I. Lindeman, Geoffrey I. Shapiro, Robert I. Haddad, Peter S. Hammerman
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (12): 2939–2949.
https://doi.org/10.1158/1078-0432.CCR-15-2314
Published: 14 June 2016
View article titled, Incorporation of Next-Generation Sequencing into Routine Clinical Care to Direct Treatment of Head and Neck Squamous Cell Carcinoma
Open the PDF for Incorporation of Next-Generation Sequencing into Routine Clinical Care to Direct Treatment of Head and Neck Squamous Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

A Single Nucleotide Polymorphism in Inflammatory Gene RNASEL Predicts Outcome after Radiation Therapy for Localized Prostate Cancer

Jonathan D. Schoenfeld, Danielle N. Margalit, Julie L. Kasperzyk, Irene M. Shui, Jennifer R. Rider, Mara M. Epstein, Allison Meisner, Stacey A. Kenfield, Neil E. Martin, Paul L. Nguyen, Philip W. Kantoff, Edward L. Giovannucci, Meir J. Stampfer, Lorelei A. Mucci
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (6): 1612–1619.
https://doi.org/10.1158/1078-0432.CCR-12-2718
Published: 14 March 2013
View article titled, A Single Nucleotide Polymorphism in Inflammatory Gene <em>RNASEL</em> Predicts Outcome after Radiation Therapy for Localized Prostate Cancer
Open the PDF for A Single Nucleotide Polymorphism in Inflammatory Gene <em>RNASEL</em> Predicts Outcome after Radiation Therapy for Localized Prostate Cancer in another window
Includes: Supplementary data