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Jonathan D. Marotti
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Journal Articles

Estrogen Therapy Induces Receptor-Dependent DNA Damage Enhanced by PARP Inhibition in ER+ Breast Cancer

Nicole A. Traphagen, Gary N. Schwartz, Steven Tau, Alyssa M. Roberts, Amanda Jiang, Sarah R. Hosford, Jonathan D. Marotti, Abigail E. Goen, Bianca A. Romo, Anneka L. Johnson, Emily-Claire K. Duffy, Eugene Demidenko, Paul Heverly, Yaron Mosesson, Shannon M. Soucy, Fred Kolling, Todd W. Miller
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (18): 3717–3728.
https://doi.org/10.1158/1078-0432.CCR-23-0488
Published: 15 September 2023
View articletitled, Estrogen Therapy Induces Receptor-Dependent DNA Damage Enhanced by PARP Inhibition in ER+ Breast Cancer
Open the PDF for Estrogen Therapy Induces Receptor-Dependent DNA Damage Enhanced by PARP Inhibition in ER+ Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Alternating 17β-Estradiol and Aromatase Inhibitor Therapies Is Efficacious in Postmenopausal Women with Advanced Endocrine-Resistant ER+ Breast Cancer

Gary N. Schwartz, Peter A. Kaufman, Karthik V. Giridhar, Jonathan D. Marotti, Mary D. Chamberlin, Bradley A. Arrick, Grace Makari-Judson, Matthew P. Goetz, Shannon M. Soucy, Fred Kolling, Eugene Demidenko, Todd W. Miller
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (15): 2767–2773.
https://doi.org/10.1158/1078-0432.CCR-23-0112
Published: 01 August 2023
View articletitled, Alternating 17β-Estradiol and Aromatase Inhibitor Therapies Is Efficacious in Postmenopausal Women with Advanced Endocrine-Resistant ER+ Breast Cancer
Open the PDF for Alternating 17β-Estradiol and Aromatase Inhibitor Therapies Is Efficacious in Postmenopausal Women with Advanced Endocrine-Resistant ER+ Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer

Margaret L. Axelrod, Mellissa J. Nixon, Paula I. Gonzalez-Ericsson, Riley E. Bergman, Mark A. Pilkinton, Wyatt J. McDonnell, Violeta Sanchez, Susan R. Opalenik, Sherene Loi, Jing Zhou, Sean Mackay, Brent N. Rexer, Vandana G. Abramson, Valerie M. Jansen, Simon Mallal, Joshua Donaldson, Sara M. Tolaney, Ian E. Krop, Ana C. Garrido-Castro, Jonathan D. Marotti, Kevin Shee, Todd W. Miller, Melinda E. Sanders, Ingrid A. Mayer, Roberto Salgado, Justin M. Balko
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (21): 5668–5681.
https://doi.org/10.1158/1078-0432.CCR-19-3685
Published: 02 November 2020
View articletitled, Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer
Open the PDF for Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer in another window
Includes: Supplementary data
Journal Articles

AMPK Activation by Metformin Promotes Survival of Dormant ER+ Breast Cancer Cells

Riley A. Hampsch, Jason D. Wells, Nicole A. Traphagen, Charlotte F. McCleery, Jennifer L. Fields, Kevin Shee, Lloye M. Dillon, Darcy B. Pooler, Lionel D. Lewis, Eugene Demidenko, Yina H. Huang, Jonathan D. Marotti, Abigail E. Goen, William B. Kinlaw, Todd W. Miller
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (14): 3707–3719.
https://doi.org/10.1158/1078-0432.CCR-20-0269
Published: 15 July 2020
View articletitled, AMPK Activation by Metformin Promotes Survival of Dormant ER+ Breast Cancer Cells
Open the PDF for AMPK Activation by Metformin Promotes Survival of Dormant ER+ Breast Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha–Positive, PIK3CA-Mutant Breast Cancer

Wei Yang, Sarah R. Hosford, Lloye M. Dillon, Kevin Shee, Stephanie C. Liu, Jennifer R. Bean, Laurent Salphati, Jodie Pang, Xiaolin Zhang, Michelle A. Nannini, Eugene Demidenko, Darcy Bates, Lionel D. Lewis, Jonathan D. Marotti, Alan R. Eastman, Todd W. Miller
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (9): 2250–2260.
https://doi.org/10.1158/1078-0432.CCR-15-2276
Published: 01 May 2016
View articletitled, Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha–Positive, PIK3CA-Mutant Breast Cancer
Open the PDF for Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha–Positive, PIK3CA-Mutant Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Androgen Receptor Expression and Breast Cancer Survival in Postmenopausal Women

Rong Hu, Shaheenah Dawood, Michelle D. Holmes, Laura C. Collins, Stuart J. Schnitt, Kimberley Cole, Jonathan D. Marotti, Susan E. Hankinson, Graham A. Colditz, Rulla M. Tamimi
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (7): 1867–1874.
https://doi.org/10.1158/1078-0432.CCR-10-2021
Published: 31 March 2011
View articletitled, Androgen Receptor Expression and Breast Cancer Survival in Postmenopausal Women
Open the PDF for Androgen Receptor Expression and Breast Cancer Survival in Postmenopausal Women in another window
Includes: Supplementary data