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John N. Weinstein
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Journal Articles

A Patient-Derived, Pan-Cancer EMT Signature Identifies Global Molecular Alterations and Immune Target Enrichment Following Epithelial-to-Mesenchymal Transition

Milena P. Mak, Pan Tong, Lixia Diao, Robert J. Cardnell, Don L. Gibbons, William N. William, Ferdinandos Skoulidis, Edwin R. Parra, Jaime Rodriguez-Canales, Ignacio I. Wistuba, John V. Heymach, John N. Weinstein, Kevin R. Coombes, Jing Wang, Lauren Averett Byers
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (3): 609–620.
https://doi.org/10.1158/1078-0432.CCR-15-0876
Published: 31 January 2016
View article titled, A Patient-Derived, Pan-Cancer EMT Signature Identifies Global Molecular Alterations and Immune Target Enrichment Following Epithelial-to-Mesenchymal Transition
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Includes: Supplementary data
Journal Articles

Invasive Bladder Cancer: Genomic Insights and Therapeutic Promise

Jaegil Kim, Rehan Akbani, Chad J. Creighton, Seth P. Lerner, John N. Weinstein, Gad Getz, David J. Kwiatkowski
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (20): 4514–4524.
https://doi.org/10.1158/1078-0432.CCR-14-1215
Published: 14 October 2015
View article titled, Invasive Bladder Cancer: Genomic Insights and Therapeutic Promise
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Journal Articles

Squamous Cell Carcinoma of the Oral Tongue in Young Non-Smokers Is Genomically Similar to Tumors in Older Smokers

Curtis R. Pickering, Jiexin Zhang, David M. Neskey, Mei Zhao, Samar A. Jasser, Jiping Wang, Alexandra Ward, C. Jillian Tsai, Marcus V. Ortega Alves, Jane H. Zhou, Jennifer Drummond, Adel K. El-Naggar, Richard Gibbs, John N. Weinstein, David A. Wheeler, Jing Wang, Mitchell J. Frederick, Jeffrey N. Myers
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (14): 3842–3848.
https://doi.org/10.1158/1078-0432.CCR-14-0565
Published: 14 July 2014
View article titled, Squamous Cell Carcinoma of the Oral Tongue in Young Non-Smokers Is Genomically Similar to Tumors in Older Smokers
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Includes: Supplementary data
Journal Articles

Tumor-Specific Isoform Switch of the Fibroblast Growth Factor Receptor 2 Underlies the Mesenchymal and Malignant Phenotypes of Clear Cell Renal Cell Carcinomas

Qi Zhao, Otavia L. Caballero, Ian D. Davis, Eric Jonasch, Pheroze Tamboli, W.K. Alfred Yung, John N. Weinstein, Kenna Shaw for the TCGA research network, Robert L. Strausberg, Jun Yao
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (9): 2460–2472.
https://doi.org/10.1158/1078-0432.CCR-12-3708
Published: 30 April 2013
View article titled, Tumor-Specific Isoform Switch of the Fibroblast Growth Factor Receptor 2 Underlies the Mesenchymal and Malignant Phenotypes of Clear Cell Renal Cell Carcinomas
Open the PDF for Tumor-Specific Isoform Switch of the Fibroblast Growth Factor Receptor 2 Underlies the Mesenchymal and Malignant Phenotypes of Clear Cell Renal Cell Carcinomas in another window
Includes: Supplementary data
Journal Articles

An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Lauren Averett Byers, Lixia Diao, Jing Wang, Pierre Saintigny, Luc Girard, Michael Peyton, Li Shen, Youhong Fan, Uma Giri, Praveen K. Tumula, Monique B. Nilsson, Jayanthi Gudikote, Hai Tran, Robert J.G. Cardnell, David J. Bearss, Steven L. Warner, Jason M. Foulks, Steven B. Kanner, Varsha Gandhi, Nancy Krett, Steven T. Rosen, Edward S. Kim, Roy S. Herbst, George R. Blumenschein, J. Jack Lee, Scott M. Lippman, K. Kian Ang, Gordon B. Mills, Waun K. Hong, John N. Weinstein, Ignacio I. Wistuba, Kevin R. Coombes, John D. Minna, John V. Heymach
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (1): 279–290.
https://doi.org/10.1158/1078-0432.CCR-12-1558
Published: 02 January 2013
View article titled, An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance
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Includes: Supplementary data
Journal Articles

Chk2 Molecular Interaction Map and Rationale for Chk2 Inhibitors

Yves Pommier, John N. Weinstein, Mirit I. Aladjem, Kurt W. Kohn
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (9): 2657–2661.
https://doi.org/10.1158/1078-0432.CCR-06-0743
Published: 04 May 2006
View article titled, Chk2 Molecular Interaction Map and Rationale for Chk2 Inhibitors
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Includes: Supplementary data
Journal Articles

Is the Gene Expression Pattern of Lung Cancer Detected by Screening With Spiral Computed Tomography Different from That of Symptom-Detected Lung Cancer?

James L. Mulshine, John N. Weinstein
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (18): 5973–5974.
https://doi.org/10.1158/1078-0432.CCR-04-1154
Published: 24 September 2004
View article titled, Is the Gene Expression Pattern of Lung Cancer Detected by Screening With Spiral Computed Tomography Different from That of Symptom-Detected Lung Cancer?
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