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John Minna
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Journal Articles

Epithelial–Mesenchymal Transition Predicts Polo-Like Kinase 1 Inhibitor–Mediated Apoptosis in Non–Small Cell Lung Cancer

Renata Ferrarotto, Ruchitha Goonatilake, Suk Young Yoo, Pan Tong, Uma Giri, Shaohua Peng, John Minna, Luc Girard, Yuehong Wang, Liguang Wang, Lerong Li, Lixia Diao, David H. Peng, Don L. Gibbons, Bonnie S. Glisson, John V. Heymach, Jing Wang, Lauren A. Byers, Faye M. Johnson
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (7): 1674–1686.
https://doi.org/10.1158/1078-0432.CCR-14-2890
Published: 31 March 2016
View article titled, Epithelial–Mesenchymal Transition Predicts Polo-Like Kinase 1 Inhibitor–Mediated Apoptosis in Non–Small Cell Lung Cancer
Open the PDF for Epithelial–Mesenchymal Transition Predicts Polo-Like Kinase 1 Inhibitor–Mediated Apoptosis in Non–Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Oncogene mutations and translocations as molecular biomarkers and targets in advanced lung adenocarcinomas

Paul A. Bunn, Mark Kris, Bruce Johnson, John Minna, David Kwiatkovski, John Iafrate, Ignacio Wistuba, Wilbur Wistuba, Marileila Varella-Garcia
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (19_Supplement): PL8-2.
https://doi.org/10.1158/DIAG-10-PL8-2
Published: 15 August 2014
View article titled, Oncogene mutations and translocations as molecular biomarkers and targets in advanced lung adenocarcinomas
Journal Articles

Adaptive Prediction Model in Prospective Molecular Signature–Based Clinical Studies

Guanghua Xiao, Shuangge Ma, John Minna, Yang Xie
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (3): 531–539.
https://doi.org/10.1158/1078-0432.CCR-13-2127
Published: 02 February 2014
View article titled, Adaptive Prediction Model in Prospective Molecular Signature–Based Clinical Studies
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Includes: Supplementary data
Journal Articles

Abstract B30: Selective small molecule AXL inhibitor BGB324 overcomes acquired drug resistance in non-small cell lung carcinoma models.

Katarzyna Wnuk-Lipinska, Gro Gausdal, Tone Sandal, Robin Frink, Stefan Hinz, Monica Hellesøy, Lavina Ahmed, Hallvard Haugen, Hallvard Haugen, Liang Xiao, Magnus Blø, David Micklem, John Minna, Rolf Brekken, Longen Zhou, James Lorens
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (2_Supplement): B30.
https://doi.org/10.1158/1078-0432.14AACRIASLC-B30
Published: 16 January 2014
View article titled, Abstract B30: Selective small molecule AXL inhibitor BGB324 overcomes acquired drug resistance in non-small cell lung carcinoma models.
Journal Articles

Abstract A12: High-throughput mutation analysis of NSCLC circulating tumor cells

Heidi S. Erickson, Nana E. Hanson, Hai Tran, Gordon B. Mills, Ed S. Kim, John V. Heymach, Ignacio I. Wistuba, Hector G. Galindo, Katherine Stemke-Hale, Uma Giri, Christina McDowell, Luc Girard, Jack J. Lee, Roy Herbst, John Minna, Farideh Z. Bischoff
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3_Supplement): A12.
https://doi.org/10.1158/1078-0432.12AACRIASLC-A12
Published: 01 February 2012
View article titled, Abstract A12: High-throughput mutation analysis of NSCLC circulating tumor cells
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Journal Articles

Abstract B42: The lineage-specific transcription factor ASCL1 defines a subtype of neuroendocrine non-small cell lung cancers with poor prognosis and points to potential therapeutic targets

Alexander Augustyn, John Minna, Christopher Tan, James Sullivan, Mark Borromeo, Luc Girard, Jane Johnson, Carmen Behrens, Ignacio Wistuba, Yang Xie
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3_Supplement): B42.
https://doi.org/10.1158/1078-0432.12AACRIASLC-B42
Published: 01 February 2012
View article titled, Abstract B42: The lineage-specific transcription factor ASCL1 defines a subtype of neuroendocrine non-small cell lung cancers with poor prognosis and points to potential therapeutic targets
Open the PDF for Abstract B42: The lineage-specific transcription factor ASCL1 defines a subtype of neuroendocrine non-small cell lung cancers with poor prognosis and points to potential therapeutic targets in another window
Journal Articles

Ethnic Differences and Functional Analysis of MET Mutations in Lung Cancer

Soundararajan Krishnaswamy, Rajani Kanteti, Jonathan S. Duke-Cohan, Sivakumar Loganathan, Wanqing Liu, Patrick C. Ma, Martin Sattler, Patrick A. Singleton, Nithya Ramnath, Federico Innocenti, Dan L. Nicolae, Zheng Ouyang, Jie Liang, John Minna, Mark F. Kozloff, Mark K. Ferguson, Viswanathan Natarajan, Yi-Ching Wang, Joe G.N. Garcia, Everett E. Vokes, Ravi Salgia
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (18): 5714–5723.
https://doi.org/10.1158/1078-0432.CCR-09-0070
Published: 14 September 2009
View article titled, Ethnic Differences and Functional Analysis of MET Mutations in Lung Cancer
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Includes: Supplementary data
Journal Articles

Fine Mapping of Chromosome 6q23-25 Region in Familial Lung Cancer Families Reveals RGS17 as a Likely Candidate Gene

Ming You, Daolong Wang, Pengyuan Liu, Haris Vikis, Michael James, Yan Lu, Yian Wang, Min Wang, Qiong Chen, Dongmei Jia, Yan Liu, Weidong Wen, Ping Yang, Zhifu Sun, Susan M. Pinney, Wei Zheng, Xiao-Ou Shu, Jirong Long, Yu-Tang Gao, Yong-Bing Xiang, Wong-Ho Chow, Nat Rothman, Gloria M. Petersen, Mariza de Andrade, Yanhong Wu, Julie M. Cunningham, Jonathan S. Wiest, Pamela R. Fain, Ann G. Schwartz, Luc Girard, Adi Gazdar, Colette Gaba, Henry Rothschild, Diptasri Mandal, Teresa Coons, Juwon Lee, Elena Kupert, Daniela Seminara, John Minna, Joan E. Bailey-Wilson, Christopher I. Amos, Marshall W. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (8): 2666–2674.
https://doi.org/10.1158/1078-0432.CCR-08-2335
Published: 15 April 2009
View article titled, Fine Mapping of Chromosome 6q23-25 Region in Familial Lung Cancer Families Reveals <em>RGS17</em> as a Likely Candidate Gene
Open the PDF for Fine Mapping of Chromosome 6q23-25 Region in Familial Lung Cancer Families Reveals <em>RGS17</em> as a Likely Candidate Gene in another window
Includes: Supplementary data
Journal Articles

Antitumor Activity of the Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor Gefitinib (ZD1839, Iressa) in Non–Small Cell Lung Cancer Cell Lines Correlates with Gene Copy Number and EGFR Mutations but not EGFR Protein Levels

Barbara A. Helfrich, David Raben, Marileila Varella-Garcia, Dan Gustafson, Daniel C. Chan, Lynne Bemis, Chris Coldren, Anna Barón, Chan Zeng, Wilbur A. Franklin, Fred R. Hirsch, Adi Gazdar, John Minna, Paul A. Bunn, Jr.
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (23): 7117–7125.
https://doi.org/10.1158/1078-0432.CCR-06-0760
Published: 04 December 2006
View article titled, Antitumor Activity of the Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor Gefitinib (ZD1839, Iressa) in Non–Small Cell Lung Cancer Cell Lines Correlates with Gene Copy Number and EGFR Mutations but not EGFR Protein Levels
Open the PDF for Antitumor Activity of the Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor Gefitinib (ZD1839, Iressa) in Non–Small Cell Lung Cancer Cell Lines Correlates with Gene Copy Number and EGFR Mutations but not EGFR Protein Levels in another window