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John Heymach
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Journal Articles

Abstract B002: Pre-vaccine radiation and CTLA-4 blockade increase adjuvant effects of SARS-COV-2 mRNA vaccines

Adam Grippin, Sage Copling, Andrew Kim, Elliana Young, Betty Kim, John Heymach, Wen Jiang, Steven H Lin
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (2_Supplement): B002.
https://doi.org/10.1158/1557-3265.TARGETEDTHERAP-B002
Published: 26 January 2025
View articletitled, Abstract B002: Pre-vaccine radiation and CTLA-4 blockade increase adjuvant effects of SARS-COV-2 mRNA vaccines
Journal Articles

FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner

Phillip M. Pifer, Liangpeng Yang, Manish Kumar, Tongxin Xie, Mitchell Frederick, Andrew Hefner, Beth Beadle, David Molkentine, Jessica Molkentine, Annika Dhawan, Mohamed Abdelhakiem, Abdullah A. Osman, Brian J. Leibowitz, Jeffrey N. Myers, Curtis R. Pickering, Vlad C. Sandulache, John Heymach, Heath D. Skinner
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (1): 187–197.
https://doi.org/10.1158/1078-0432.CCR-23-0964
Published: 05 January 2024
View articletitled, FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner
Open the PDF for FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner in another window
Includes: Supplementary data
Journal Articles

Tepotinib Efficacy and Safety in Patients with MET Exon 14 Skipping NSCLC: Outcomes in Patient Subgroups from the VISION Study with Relevance for Clinical Practice

Xiuning Le, Hiroshi Sakai, Enriqueta Felip, Remi Veillon, Marina Chiara Garassino, Jo Raskin, Alexis B. Cortot, Santiago Viteri, Julien Mazieres, Egbert F. Smit, Michael Thomas, Wade T. Iams, Byoung Chul Cho, Hye Ryun Kim, James Chih-Hsin Yang, Yuh-Min Chen, Jyoti D. Patel, Christine M. Bestvina, Keunchil Park, Frank Griesinger, Melissa Johnson, Maya Gottfried, Christian Britschgi, John Heymach, Elif Sikoglu, Karin Berghoff, Karl-Maria Schumacher, Rolf Bruns, Gordon Otto, Paul K. Paik
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (6): 1117–1126.
https://doi.org/10.1158/1078-0432.CCR-21-2733
Published: 15 March 2022
View articletitled, Tepotinib Efficacy and Safety in Patients with MET Exon 14 Skipping NSCLC: Outcomes in Patient Subgroups from the VISION Study with Relevance for Clinical Practice
Open the PDF for Tepotinib Efficacy and Safety in Patients with MET Exon 14 Skipping NSCLC: Outcomes in Patient Subgroups from the VISION Study with Relevance for Clinical Practice in another window
Includes: Supplementary data
Journal Articles

VEGF/VEGFR-2 Upregulates EZH2 Expression in Lung Adenocarcinoma Cells and EZH2 Depletion Enhances the Response to Platinum-Based and VEGFR-2–Targeted Therapy

Erick Riquelme, Milind Suraokar, Carmen Behrens, Heather Y. Lin, Luc Girard, Monique B. Nilsson, George Simon, Jing Wang, Kevin R. Coombes, J. Jack Lee, Waun Ki Hong, John Heymach, John D. Minna, Ignacio I. Wistuba
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (14): 3849–3861.
https://doi.org/10.1158/1078-0432.CCR-13-1916
Published: 14 July 2014
View articletitled, VEGF/VEGFR-2 Upregulates EZH2 Expression in Lung Adenocarcinoma Cells and EZH2 Depletion Enhances the Response to Platinum-Based and VEGFR-2–Targeted Therapy
Open the PDF for VEGF/VEGFR-2 Upregulates EZH2 Expression in Lung Adenocarcinoma Cells and EZH2 Depletion Enhances the Response to Platinum-Based and VEGFR-2–Targeted Therapy in another window
Includes: Supplementary data
Journal Articles

Abstract IA21: Developing a new functional classification of lung cancer based on tumor acquired vulnerabilities.

John D. Minna, Adi Gazdar, Alexander Augustyn, Rebecca Britt, Ryan Carstens, Patrick Dospoy, Boning Gao, Luc Girard, Suzie Hight, Kenneth Huffman, Jill Larsen, Michael Peyton, Chunli Shao, David Mangelsdorf, Rolf Brekken, Ralph Deberardinis, Pei-Hsuan Chen, Carmen Behrens, Lauren Byers, John Heymach, Jack Roth, Ignacio Wistuba, Yang Xie, Caleb Davis, David Wheeler, Richard Gibbs, Edward Marcotte, Joseph Ready, Deepak Nijhawan, Noelle Williams, Steven McKnight, Bruce Posner, John MacMillan, Michael Roth, Michael White
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (2_Supplement): IA21.
https://doi.org/10.1158/1078-0432.14AACRIASLC-IA21
Published: 16 January 2014
View articletitled, Abstract IA21: Developing a new functional classification of lung cancer based on tumor acquired vulnerabilities.
Journal Articles

Beyond VEGF: Inhibition of the Fibroblast Growth Factor Pathway and Antiangiogenesis

Christopher Lieu, John Heymach, Michael Overman, Hai Tran, Scott Kopetz
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (19): 6130–6139.
https://doi.org/10.1158/1078-0432.CCR-11-0659
Published: 02 October 2011
View articletitled, Beyond VEGF: Inhibition of the Fibroblast Growth Factor Pathway and Antiangiogenesis
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Journal Articles

Vandetanib Restores Head and Neck Squamous Cell Carcinoma Cells' Sensitivity to Cisplatin and Radiation In Vivo and In Vitro

Daisuke Sano, Fumihiko Matsumoto, David R. Valdecanas, Mei Zhao, David P. Molkentine, Yoko Takahashi, Ehab Y. Hanna, Vali Papadimitrakopoulou, John Heymach, Luka Milas, Jeffrey N. Myers
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (7): 1815–1827.
https://doi.org/10.1158/1078-0432.CCR-10-2120
Published: 31 March 2011
View articletitled, Vandetanib Restores Head and Neck Squamous Cell Carcinoma Cells' Sensitivity to Cisplatin and Radiation In Vivo and In Vitro
Open the PDF for Vandetanib Restores Head and Neck Squamous Cell Carcinoma Cells' Sensitivity to Cisplatin and Radiation In Vivo and In Vitro in another window
Includes: Supplementary data
Journal Articles

Epidermal Growth Factor Receptor Blockade in Combination with Conventional Chemotherapy Inhibits Soft Tissue Sarcoma Cell Growth In vitro and In vivo

Wenhong Ren, Borys Korchin, Quan-Sheng Zhu, Caimiao Wei, Adam Dicker, John Heymach, Alexander Lazar, Raphael E. Pollock, Dina Lev
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (9): 2785–2795.
https://doi.org/10.1158/1078-0432.CCR-07-4471
Published: 01 May 2008
View articletitled, Epidermal Growth Factor Receptor Blockade in Combination with Conventional Chemotherapy Inhibits Soft Tissue Sarcoma Cell Growth In vitro and In vivo
Open the PDF for Epidermal Growth Factor Receptor Blockade in Combination with Conventional Chemotherapy Inhibits Soft Tissue Sarcoma Cell Growth In vitro and In vivo in another window