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John G. Kuhn
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Journal Articles

Phase I and Biomarker Study of Plerixafor and Bevacizumab in Recurrent High-Grade Glioma

Eudocia Q. Lee, Dan G. Duda, Alona Muzikansky, Elizabeth R. Gerstner, John G. Kuhn, David A. Reardon, Lakshmi Nayak, Andrew D. Norden, Lisa Doherty, Debra LaFrankie, Jennifer Stefanik, Trupti Vardam, Katrina H. Smith, Christine McCluskey, Sarah Gaffey, Tracy T. Batchelor, Rakesh K. Jain, Patrick Y. Wen
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (19): 4643–4649.
https://doi.org/10.1158/1078-0432.CCR-18-1025
Published: 01 October 2018
View article titled, Phase I and Biomarker Study of Plerixafor and Bevacizumab in Recurrent High-Grade Glioma
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Journal Articles

Pharmacological Inhibition of NOS Activates ASK1/JNK Pathway Augmenting Docetaxel-Mediated Apoptosis in Triple-Negative Breast Cancer

Daniel Dávila-González, Dong Soon Choi, Roberto R. Rosato, Sergio M. Granados-Principal, John G. Kuhn, Wen-Feng Li, Wei Qian, Wen Chen, Anthony J. Kozielski, Helen Wong, Bhuvanesh Dave, Jenny C. Chang
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (5): 1152–1162.
https://doi.org/10.1158/1078-0432.CCR-17-1437
Published: 28 February 2018
View article titled, Pharmacological Inhibition of NOS Activates ASK1/JNK Pathway Augmenting Docetaxel-Mediated Apoptosis in Triple-Negative Breast Cancer
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Includes: Supplementary data
Journal Articles

Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma

Sara A. Byron, Nhan L. Tran, Rebecca F. Halperin, Joanna J. Phillips, John G. Kuhn, John F. de Groot, Howard Colman, Keith L. Ligon, Patrick Y. Wen, Timothy F. Cloughesy, Ingo K. Mellinghoff, Nicholas A. Butowski, Jennie W. Taylor, Jennifer L. Clarke, Susan M. Chang, Mitchel S. Berger, Annette M. Molinaro, Gerald M. Maggiora, Sen Peng, Sara Nasser, Winnie S. Liang, Jeffrey M. Trent, Michael E. Berens, John D. Carpten, David W. Craig, Michael D. Prados
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (2): 295–305.
https://doi.org/10.1158/1078-0432.CCR-17-0963
Published: 15 January 2018
View article titled, Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma
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Includes: Supplementary data
Journal Articles

Phase I Study of Vorinostat in Combination with Temozolomide in Patients with High-Grade Gliomas: North American Brain Tumor Consortium Study 04-03

Eudocia Q. Lee, Vinay K. Puduvalli, Joel M. Reid, John G. Kuhn, Kathleen R. Lamborn, Timothy F. Cloughesy, Susan M. Chang, Jan Drappatz, W. K. Alfred Yung, Mark R. Gilbert, H. Ian Robins, Frank S. Lieberman, Andrew B. Lassman, Renee M. McGovern, Jihong Xu, Serena Desideri, Xiabu Ye, Matthew M. Ames, Igor Espinoza-Delgado, Michael D. Prados, Patrick Y. Wen
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (21): 6032–6039.
https://doi.org/10.1158/1078-0432.CCR-12-1841
Published: 06 November 2012
View article titled, Phase I Study of Vorinostat in Combination with Temozolomide in Patients with High-Grade Gliomas: North American Brain Tumor Consortium Study 04-03
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Includes: Supplementary data
Journal Articles

Pharmacokinetic and Tumor Distribution Characteristics of Temsirolimus in Patients with Recurrent Malignant Glioma

John G. Kuhn, Susan M. Chang, Patrick Y. Wen, Timothy F. Cloughesy, Harry Greenberg, David Schiff, Charles Conrad, Karen L. Fink, H. Ian Robins, Minesh Mehta, Lisa DeAngelis, Jeffrey Raizer, Kenneth Hess, Kathleen R. Lamborn, Janet Dancey, Michael D. Prados, for the North American Brain Tumor Consortium and the National Cancer Institute
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (24): 7401–7406.
https://doi.org/10.1158/1078-0432.CCR-07-0781
Published: 19 December 2007
View article titled, Pharmacokinetic and Tumor Distribution Characteristics of Temsirolimus in Patients with Recurrent Malignant Glioma
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Journal Articles

Phase 1 and Pharmacokinetic Study of Intravenous Irinotecan in Refractory Solid Tumor Patients with Hepatic Dysfunction

Larry J. Schaaf, Lisa A. Hammond, Stuart J. Tipping, Richard M. Goldberg, Rakesh Goel, John G. Kuhn, Langdon L. Miller, Linda D. Compton, Laura A. Cisar, Gary L. Elfring, Gabriela Gruia, J. Patrick McGovren, Nicoletta Pirotta, Donghua Yin, Amarnath Sharma, Barbara A. Duncan, Mace L. Rothenberg
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (12): 3782–3791.
https://doi.org/10.1158/1078-0432.CCR-05-2152
Published: 15 June 2006
View article titled, Phase 1 and Pharmacokinetic Study of Intravenous Irinotecan in Refractory Solid Tumor Patients with Hepatic Dysfunction
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Journal Articles

Phase I and Pharmacokinetic Study of Sequences of the Rebeccamycin Analogue NSC 655649 and Cisplatin in Patients with Advanced Solid Tumors

Alejandro D. Ricart, Lisa A. Hammond, John G. Kuhn, Chris H. Takimoto, Andrew Goetz, Bahram Forouzesh, Leonardo Forero, Jose L. Ochoa-Bayona, Kristin Berg, Anthony W. Tolcher, Eric K. Rowinsky
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (24): 8728–8736.
https://doi.org/10.1158/1078-0432.CCR-05-1572
Published: 16 December 2005
View article titled, Phase I and Pharmacokinetic Study of Sequences of the Rebeccamycin Analogue NSC 655649 and Cisplatin in Patients with Advanced Solid Tumors
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Journal Articles

Molecular Study of Malignant Gliomas Treated with Epidermal Growth Factor Receptor Inhibitors: Tissue Analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01

Andrew B. Lassman, Michael R. Rossi, Jeffrey R. Razier, Lauren E. Abrey, Frank S. Lieberman, Chelsea N. Grefe, Kathleen Lamborn, William Pao, Alan H. Shih, John G. Kuhn, Richard Wilson, Norma J. Nowak, John K. Cowell, Lisa M. DeAngelis, Patrick Wen, Mark R. Gilbert, Susan Chang, W.A. Yung, Michael Prados, Eric C. Holland
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (21): 7841–7850.
https://doi.org/10.1158/1078-0432.CCR-05-0421
Published: 08 November 2005
View article titled, Molecular Study of Malignant Gliomas Treated with Epidermal Growth Factor Receptor Inhibitors: Tissue Analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01
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Includes: Supplementary data
Journal Articles

A Phase I and Pharmacokinetic Study of Col-3 (Metastat), an Oral Tetracycline Derivative with Potent Matrix Metalloproteinase and Antitumor Properties

Samira Syed, Chris Takimoto, Manuel Hidalgo, Jinee Rizzo, John G. Kuhn, Lisa A. Hammond, Garry Schwartz, Anthony Tolcher, Amita Patnaik, S. Gail Eckhardt, Eric K. Rowinsky
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (19): 6512–6521.
https://doi.org/10.1158/1078-0432.CCR-04-0804
Published: 08 October 2004
View article titled, A Phase I and Pharmacokinetic Study of Col-3 (Metastat), an Oral Tetracycline Derivative with Potent Matrix Metalloproteinase and Antitumor Properties
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Journal Articles

A Randomized Phase I and Pharmacological Trial of Sequences of 1,3-bis(2-Chloroethyl)-1-Nitrosourea and Temozolomide in Patients with Advanced Solid Neoplasms

Lisa A. Hammond, John R. Eckardt, John G. Kuhn, Stanton L. Gerson, Tom Johnson, Lon Smith, Ronald L. Drengler, Elizabeth Campbell, Geoffrey R. Weiss, Daniel D. Von Hoff, Eric K. Rowinsky
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (5): 1645–1656.
https://doi.org/10.1158/1078-0432.CCR-03-0174
Published: 10 March 2004
View article titled, A Randomized Phase I and Pharmacological Trial of Sequences of 1,3-bis(2-Chloroethyl)-1-Nitrosourea and Temozolomide in Patients with Advanced Solid Neoplasms
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Journal Articles

Effects of Hydroxyurea on Extrachromosomal DNA in Patients with Advanced Ovarian Carcinomas

Eric Raymond, Sandrine Faivre, Geoffrey Weiss, John McGill, Karen Davidson, Elzbieta Izbicka, John G. Kuhn, Craig Allred, Gary M. Clark, Daniel D. Von Hoff
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (5): 1171–1180.
Published: 01 May 2001
View article titled, Effects of Hydroxyurea on Extrachromosomal DNA in Patients with Advanced Ovarian Carcinomas
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Journal Articles

9-cis-Retinoic Acid Suppresses Mammary Tumorigenesis in C3(1)-Simian Virus 40 T Antigen-transgenic Mice

Kendall Wu, Hee-Tae Kim, Jenny L. Rodriquez, Deborah Munoz-Medellin, Syed K. Mohsin, Susan G. Hilsenbeck, William W. Lamph, Marco M. Gottardis, Michael A. Shirley, John G. Kuhn, Jeff E. Green, Powel H. Brown
Journal: Clinical Cancer Research
Clin Cancer Res (2000) 6 (9): 3696–3704.
Published: 01 September 2000
View article titled, 9-<em>cis</em>-Retinoic Acid Suppresses Mammary Tumorigenesis in C3(1)-Simian Virus 40 T Antigen-transgenic Mice
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