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Johannes M. Heuckmann
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Journal Articles

Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients

Dennis Plenker, Miriam Bertrand, Adrianus J. de Langen, Richard Riedel, Carina Lorenz, Andreas H. Scheel, Judith Müller, Johannes Brägelmann, Juliane Daßler-Plenker, Carsten Kobe, Thorsten Persigehl, Alexander Kluge, Thomas Wurdinger, Pepijn Schellen, Gunther Hartmann, Tobias Zacherle, Roopika Menon, Erik Thunnissen, Reinhard Büttner, Frank Griesinger, Jürgen Wolf, Lukas Heukamp, Martin L. Sos, Johannes M. Heuckmann
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (6): 1337–1343.
https://doi.org/10.1158/1078-0432.CCR-17-3001
Published: 14 March 2018
View articletitled, Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients
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Includes: Supplementary data
Journal Articles

Mechanisms of Primary Drug Resistance in FGFR1-Amplified Lung Cancer

Florian Malchers, Meryem Ercanoglu, Daniel Schütte, Roberta Castiglione, Verena Tischler, Sebastian Michels, Ilona Dahmen, Johannes Brägelmann, Roopika Menon, Johannes M. Heuckmann, Julie George, Sascha Ansén, Martin L. Sos, Alex Soltermann, Martin Peifer, Jürgen Wolf, Reinhard Büttner, Roman K. Thomas
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2017) 23 (18): 5527–5536.
https://doi.org/10.1158/1078-0432.CCR-17-0478
Published: 14 September 2017
View articletitled, Mechanisms of Primary Drug Resistance in FGFR1-Amplified Lung Cancer
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Includes: Supplementary data
Journal Articles

Heterogeneous Mechanisms of Primary and Acquired Resistance to Third-Generation EGFR Inhibitors

Sandra Ortiz-Cuaran, Matthias Scheffler, Dennis Plenker, llona Dahmen, Andreas H. Scheel, Lynnette Fernandez-Cuesta, Lydia Meder, Christine M. Lovly, Thorsten Persigehl, Sabine Merkelbach-Bruse, Marc Bos, Sebastian Michels, Rieke Fischer, Kerstin Albus, Katharina König, Hans-Ulrich Schildhaus, Jana Fassunke, Michaela A. Ihle, Helen Pasternack, Carina Heydt, Christian Becker, Janine Altmüller, Hongbin Ji, Christian Müller, Alexandra Florin, Johannes M. Heuckmann, Peter Nuernberg, Sascha Ansén, Lukas C. Heukamp, Johannes Berg, William Pao, Martin Peifer, Reinhard Buettner, Jürgen Wolf, Roman K. Thomas, Martin L. Sos
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (19): 4837–4847.
https://doi.org/10.1158/1078-0432.CCR-15-1915
Published: 02 October 2016
View articletitled, Heterogeneous Mechanisms of Primary and Acquired Resistance to Third-Generation EGFR Inhibitors
Open the PDF for Heterogeneous Mechanisms of Primary and Acquired Resistance to Third-Generation EGFR Inhibitors in another window
Includes: Supplementary data
Journal Articles

Differential Protein Stability and ALK Inhibitor Sensitivity of EML4-ALK Fusion Variants

Johannes M. Heuckmann, Hyatt Balke-Want, Florian Malchers, Martin Peifer, Martin L. Sos, Mirjam Koker, Lydia Meder, Christine M. Lovly, Lukas C. Heukamp, William Pao, Ralf Küppers, Roman K. Thomas
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (17): 4682–4690.
https://doi.org/10.1158/1078-0432.CCR-11-3260
Published: 30 August 2012
View articletitled, Differential Protein Stability and ALK Inhibitor Sensitivity of EML4-ALK Fusion Variants
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Includes: Supplementary data
Journal Articles

ALK Mutations Conferring Differential Resistance to Structurally Diverse ALK Inhibitors

Johannes M. Heuckmann, Michael Hölzel, Martin L. Sos, Stefanie Heynck, Hyatt Balke-Want, Mirjam Koker, Martin Peifer, Jonathan Weiss, Christine M. Lovly, Christian Grütter, Daniel Rauh, William Pao, Roman K. Thomas
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (23): 7394–7401.
https://doi.org/10.1158/1078-0432.CCR-11-1648
Published: 30 November 2011
View articletitled, ALK Mutations Conferring Differential Resistance to Structurally Diverse ALK Inhibitors
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Includes: Supplementary data