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Johannes H. Schulte
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Journal Articles

Targeted Analysis of Cell-free Circulating Tumor DNA is Suitable for Early Relapse and Actionable Target Detection in Patients with Neuroblastoma

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Marco Lodrini, Josefine Graef, Theresa M. Thole-Kliesch, Kathy Astrahantseff, Annika Sprüssel, Maddalena Grimaldi, Constantin Peitz, Rasmus B. Linke, Jan F. Hollander, Erwin Lankes, Annette Künkele, Lena Oevermann, Georg Schwabe, Jörg Fuchs, Annabell Szymansky, Johannes H. Schulte, Patrick Hundsdörfer, Cornelia Eckert, Holger Amthauer, Angelika Eggert, Hedwig E. Deubzer
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (9): 1809–1820.
https://doi.org/10.1158/1078-0432.CCR-21-3716
Published: 02 May 2022
View articletitled, Targeted Analysis of Cell-free Circulating Tumor DNA is Suitable for Early Relapse and Actionable Target Detection in Patients with Neuroblastoma
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Includes: Supplementary data
Journal Articles

ALK Inhibitors in Neuroblastoma: A Sprint from Bench to Bedside

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Johannes H. Schulte, Angelika Eggert
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (13): 3507–3509.
https://doi.org/10.1158/1078-0432.CCR-21-0627
Published: 01 July 2021
View articletitled, ALK Inhibitors in Neuroblastoma: A Sprint from Bench to Bedside
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Journal Articles

Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition

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Anton Henssen, Kristina Althoff, Andrea Odersky, Anneleen Beckers, Richard Koche, Frank Speleman, Simon Schäfers, Emma Bell, Maike Nortmeyer, Frank Westermann, Katleen De Preter, Alexandra Florin, Lukas Heukamp, Annika Spruessel, Kathy Astrahanseff, Sven Lindner, Natalie Sadowski, Alexander Schramm, Lucile Astorgues-Xerri, Maria E. Riveiro, Angelika Eggert, Esteban Cvitkovic, Johannes H. Schulte
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (10): 2470–2481.
https://doi.org/10.1158/1078-0432.CCR-15-1449
Published: 12 May 2016
View articletitled, Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition
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Includes: Supplementary data
Journal Articles

Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment

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Irina Lambertz, Candy Kumps, Shana Claeys, Sven Lindner, Anneleen Beckers, Els Janssens, Daniel R. Carter, Alex Cazes, Belamy B. Cheung, Marilena De Mariano, An De Bondt, Sara De Brouwer, Olivier Delattre, Jay Gibbons, Isabelle Janoueix-Lerosey, Geneviève Laureys, Chris Liang, Glenn M. Marchall, Michael Porcu, Junko Takita, David Camacho Trujillo, Ilse Van Den Wyngaert, Nadine Van Roy, Alan Van Goethem, Tom Van Maerken, Piotr Zabrocki, Jan Cools, Johannes H. Schulte, Jorge Vialard, Frank Speleman, Katleen De Preter
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (14): 3327–3339.
https://doi.org/10.1158/1078-0432.CCR-14-2024
Published: 14 July 2015
View articletitled, Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment
Open the PDF for Upregulation of MAPK Negative Feedback Regulators and RET in Mutant ALK Neuroblastoma: Implications for Targeted Treatment in another window
Includes: Supplementary data
Journal Articles

miRNA Expression Profiling Enables Risk Stratification in Archived and Fresh Neuroblastoma Tumor Samples

Free
Katleen De Preter, Pieter Mestdagh, Joëlle Vermeulen, Fjoralba Zeka, Arlene Naranjo, Isabella Bray, Victoria Castel, Caifu Chen, Elzbieta Drozynska, Angelika Eggert, Michael D. Hogarty, Ewa Iżycka-Swieszewska, Wendy B. London, Rosa Noguera, Marta Piqueras, Kenneth Bryan, Benjamin Schowe, Peter van Sluis, Jan J. Molenaar, Alexander Schramm, Johannes H. Schulte, Raymond L. Stallings, Rogier Versteeg, Geneviève Laureys, Nadine Van Roy, Frank Speleman, Jo Vandesompele
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (24): 7684–7692.
https://doi.org/10.1158/1078-0432.CCR-11-0610
Published: 18 December 2011
View articletitled, miRNA Expression Profiling Enables Risk Stratification in Archived and Fresh Neuroblastoma Tumor Samples
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Includes: Supplementary data
Journal Articles

High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation as a Determining Factor of an Unfavorable Phenotype in Primary Neuroblastoma

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Johannes H. Schulte, Hagen S. Bachmann, Bent Brockmeyer, Katleen DePreter, André Oberthür, Sandra Ackermann, Yvonne Kahlert, Kristian Pajtler, Jessica Theissen, Frank Westermann, Jo Vandesompele, Frank Speleman, Frank Berthold, Angelika Eggert, Benedikt Brors, Barbara Hero, Alexander Schramm, Matthias Fischer
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (15): 5082–5092.
https://doi.org/10.1158/1078-0432.CCR-10-2809
Published: 31 July 2011
View articletitled, High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation as a Determining Factor of an Unfavorable Phenotype in Primary Neuroblastoma
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Includes: Supplementary data
Journal Articles

Polo-Like Kinase 1 is a Therapeutic Target in High-Risk Neuroblastoma

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Sandra Ackermann, Felix Goeser, Johannes H. Schulte, Alexander Schramm, Volker Ehemann, Barbara Hero, Angelika Eggert, Frank Berthold, Matthias Fischer
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (4): 731–741.
https://doi.org/10.1158/1078-0432.CCR-10-1129
Published: 15 February 2011
View articletitled, Polo-Like Kinase 1 is a Therapeutic Target in High-Risk Neuroblastoma
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Journal Articles

Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification

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Sara De Brouwer, Katleen De Preter, Candy Kumps, Piotr Zabrocki, Michaël Porcu, Ellen M. Westerhout, Arjan Lakeman, Jo Vandesompele, Jasmien Hoebeeck, Tom Van Maerken, Anne De Paepe, Geneviève Laureys, Johannes H. Schulte, Alexander Schramm, Caroline Van Den Broecke, Joëlle Vermeulen, Nadine Van Roy, Klaus Beiske, Marleen Renard, Rosa Noguera, Olivier Delattre, Isabelle Janoueix-Lerosey, Per Kogner, Tommy Martinsson, Akira Nakagawara, Miki Ohira, Huib Caron, Angelika Eggert, Jan Cools, Rogier Versteeg, Frank Speleman
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (17): 4353–4362.
https://doi.org/10.1158/1078-0432.CCR-09-2660
Published: 31 August 2010
View articletitled, Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification
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Includes: Supplementary data
Journal Articles

Chromosomal and MicroRNA Expression Patterns Reveal Biologically Distinct Subgroups of 11q− Neuroblastoma

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Patrick G. Buckley, Leah Alcock, Kenneth Bryan, Isabella Bray, Johannes H. Schulte, Alexander Schramm, Angelika Eggert, Pieter Mestdagh, Katleen De Preter, Jo Vandesompele, Frank Speleman, Raymond L. Stallings
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (11): 2971–2978.
https://doi.org/10.1158/1078-0432.CCR-09-3215
Published: 31 May 2010
View articletitled, Chromosomal and MicroRNA Expression Patterns Reveal Biologically Distinct Subgroups of 11q− Neuroblastoma
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Includes: Supplementary data
Journal Articles

Accurate Outcome Prediction in Neuroblastoma across Independent Data Sets Using a Multigene Signature

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Katleen De Preter, Joëlle Vermeulen, Benedikt Brors, Olivier Delattre, Angelika Eggert, Matthias Fischer, Isabelle Janoueix-Lerosey, Cinzia Lavarino, John M. Maris, Jaume Mora, Akira Nakagawara, André Oberthuer, Miki Ohira, Gudrun Schleiermacher, Alexander Schramm, Johannes H. Schulte, Qun Wang, Frank Westermann, Frank Speleman, Jo Vandesompele
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (5): 1532–1541.
https://doi.org/10.1158/1078-0432.CCR-09-2607
Published: 28 February 2010
View articletitled, Accurate Outcome Prediction in Neuroblastoma across Independent Data Sets Using a Multigene Signature
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Includes: Supplementary data
Journal Articles

Translating Expression Profiling into a Clinically Feasible Test to Predict Neuroblastoma Outcome

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Alexander Schramm, Jo Vandesompele, Johannes H. Schulte, Sabine Dreesmann, Lars Kaderali, Benedikt Brors, Roland Eils, Frank Speleman, Angelika Eggert
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (5): 1459–1465.
https://doi.org/10.1158/1078-0432.CCR-06-2032
Published: 01 March 2007
View articletitled, Translating Expression Profiling into a Clinically Feasible Test to Predict Neuroblastoma Outcome
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