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Journal Articles

Abstract A034: Addressing the challenge of pre-analytical variables in circulating protein biomarker analysis for liquid biopsy

Rachel M Miller, Jing Li
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (21_Supplement): A034.
https://doi.org/10.1158/1557-3265.LIQBIOP24-A034
Published: 13 November 2024
View article titled, Abstract A034: Addressing the challenge of pre-analytical variables in circulating protein biomarker analysis for liquid biopsy
Journal Articles

Co-occurring EGFR p.E709X Mutation Mediates Primary Resistance to the Third-Generation EGFR-TKIs in EGFR p.G719X-Mutant Patients with Advanced NSCLC

Lanlan Pang, Yihua Huang, Weitao Zhuang, Yaxiong Zhang, Jun Liao, Yue Hao, Feng Hao, Guoqian Wang, Ze-xin Chase Chen, Yu Zhu, Mengzhen Li, Zhengbo Song, Bo Peng Deng, Jing Li, Li Zhang, Wenfeng Fang
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (12): 2636–2646.
https://doi.org/10.1158/1078-0432.CCR-23-3302
Published: 14 June 2024
View article titled, Co-occurring EGFR p.E709X Mutation Mediates Primary Resistance to the Third-Generation EGFR-TKIs in EGFR p.G719X-Mutant Patients with Advanced NSCLC
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Includes: Supplementary data
Journal Articles

Mechanistic Modeling of Intrathecal Chemotherapy Pharmacokinetics in the Human Central Nervous System

Jing Li, Andrew Wu, Seongho Kim
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (7): 1397–1408.
https://doi.org/10.1158/1078-0432.CCR-23-3062
Published: 01 April 2024
View article titled, Mechanistic Modeling of Intrathecal Chemotherapy Pharmacokinetics in the Human Central Nervous System
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Includes: Supplementary data
Journal Articles

FDA Approval Summary: Ivosidenib in Combination with Azacitidine for Treatment of Patients with Newly Diagnosed Acute Myeloid Leukemia with an IDH1 Mutation

Ashley Woods, Kelly J. Norsworthy, Xin Wang, Jonathon Vallejo, Edwin Chiu Yuen Chow, Ruo-Jing Li, Jielin Sun, Rosane Charlab, Xiling Jiang, Richard Pazdur, Marc R. Theoret, R. Angelo de Claro
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (7): 1226–1231.
https://doi.org/10.1158/1078-0432.CCR-23-2234
Published: 01 April 2024
View article titled, FDA Approval Summary: Ivosidenib in Combination with Azacitidine for Treatment of Patients with Newly Diagnosed Acute Myeloid Leukemia with an <em>IDH1</em> Mutation
Open the PDF for FDA Approval Summary: Ivosidenib in Combination with Azacitidine for Treatment of Patients with Newly Diagnosed Acute Myeloid Leukemia with an <em>IDH1</em> Mutation in another window
Includes: Supplementary data
Journal Articles

Mechanistic Modeling of Central Nervous System Pharmacokinetics and Target Engagement of HER2 Tyrosine Kinase Inhibitors to Inform Treatment of Breast Cancer Brain Metastases

Jing Li, Jun Jiang, Xun Bao, Vineet Kumar, Stephen C. Alley, Scott Peterson, Anthony J. Lee
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (15): 3329–3341.
https://doi.org/10.1158/1078-0432.CCR-22-0405
Published: 02 August 2022
View article titled, Mechanistic Modeling of Central Nervous System Pharmacokinetics and Target Engagement of HER2 Tyrosine Kinase Inhibitors to Inform Treatment of Breast Cancer Brain Metastases
Open the PDF for Mechanistic Modeling of Central Nervous System Pharmacokinetics and Target Engagement of HER2 Tyrosine Kinase Inhibitors to Inform Treatment of Breast Cancer Brain Metastases in another window
Includes: Supplementary data
Journal Articles

FDA Approval Summary: Belumosudil for Adult and Pediatric Patients 12 Years and Older with Chronic GvHD after Two or More Prior Lines of Systemic Therapy

Donna Przepiorka, Robert Q. Le, Alexei Ionan, Ruo-Jing Li, Ying-Hong Wang, Ramadevi Gudi, Soumya Mitra, Jonathon Vallejo, Olanrewaju O. Okusanya, Lian Ma, Yuching Yang, Paresma Patel, Djelila Mezaache, Rakhi Shah, Anamitro Banerjee, Sherita McLamore, Adam N. Maung, Kirsten B. Goldberg, Richard Pazdur, Marc R. Theoret, R. Angelo De Claro
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (12): 2488–2492.
https://doi.org/10.1158/1078-0432.CCR-21-4176
Published: 13 June 2022
View article titled, FDA Approval Summary: Belumosudil for Adult and Pediatric Patients 12 Years and Older with Chronic GvHD after Two or More Prior Lines of Systemic Therapy
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Includes: Supplementary data
Journal Articles

A Phase 0 Trial of Ceritinib in Patients with Brain Metastases and Recurrent Glioblastoma

Shwetal Mehta, Roberto Fiorelli, Xun Bao, Chelsea Pennington-Krygier, Alanna Derogatis, Seongho Kim, Wonsuk Yoo, Jing Li, Nader Sanai
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (2): 289–297.
https://doi.org/10.1158/1078-0432.CCR-21-1096
Published: 19 January 2022
View article titled, A Phase 0 Trial of Ceritinib in Patients with Brain Metastases and Recurrent Glioblastoma
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Journal Articles

Pyrotinib Treatment in Patients With HER2-positive Metastatic Breast Cancer and Brain Metastasis: Exploratory Final Analysis of Real-World, Multicenter Data

Munawar Anwar, Qitong Chen, Dengjie Ouyang, Shouman Wang, Ning Xie, Quchang Ouyang, Peizhi Fan, Liyuan Qian, Gannong Chen, Enxiang Zhou, Lei Guo, Xiaowen Gu, Boning Ding, Xiaohong Yang, Liping Liu, Chao Deng, Zhi Xiao, Jing Li, Yunqi Wang, Shan Zeng, Jinhui Hu, Wei Zhou, Bo Qiu, Zhongming Wang, Jie Weng, Mingwen Liu, Yi Li, Tiegang Tang, Jianguo Wang, Hui Zhang, Bin Dai, Wuping Tang, Tao Wu, Maoliang Xiao, Xiantao Li, Hailong Liu, Lai Li, Wenjun Yi
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (16): 4634–4641.
https://doi.org/10.1158/1078-0432.CCR-21-0474
Published: 15 August 2021
View article titled, Pyrotinib Treatment in Patients With HER2-positive Metastatic Breast Cancer and Brain Metastasis: Exploratory Final Analysis of Real-World, Multicenter Data
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Includes: Supplementary data
Journal Articles

High FLT3 Levels May Predict Sorafenib Benefit in Hepatocellular Carcinoma

Wen Sun, Shi-Chao Li, Li Xu, Wei Zhong, Zhen-Guang Wang, Chu-zhi Pan, Jing Li, Guang-Zhi Jin, Na Ta, Wei Dong, Dan Liu, Hui Liu, Hong-Yang Wang, Jin Ding
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (16): 4302–4312.
https://doi.org/10.1158/1078-0432.CCR-19-1858
Published: 14 August 2020
View article titled, High FLT3 Levels May Predict Sorafenib Benefit in Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

FDA Approval Summary: Calaspargase Pegol-mknl For Treatment of Acute Lymphoblastic Leukemia in Children and Young Adults

Ruo-Jing Li, Runyan Jin, Chao Liu, Xianhua Cao, Michael L. Manning, Xu Michael Di, Donna Przepiorka, Frances Namuswe, Albert Deisseroth, Kirsten B. Goldberg, Gideon M. Blumenthal, Richard Pazdur
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (2): 328–331.
https://doi.org/10.1158/1078-0432.CCR-19-1255
Published: 15 January 2020
View article titled, FDA Approval Summary: Calaspargase Pegol-mknl For Treatment of Acute Lymphoblastic Leukemia in Children and Young Adults
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Includes: Supplementary data
Journal Articles

ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer

Zhuqing Li, Wei Zhou, Yi Zhang, Wei Sun, Mingo M.H. Yung, Jing Sun, Jing Li, Chi-Wei Chen, Zongzhu Li, Yunxiao Meng, Jie Chai, Yuan Zhou, Stephanie S. Liu, Annie N.Y. Cheung, Hextan Y.S. Ngan, David W. Chan, Wei Zheng, Wenge Zhu
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (19): 5947–5960.
https://doi.org/10.1158/1078-0432.CCR-18-4145
Published: 01 October 2019
View article titled, ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer
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Includes: Supplementary data
Journal Articles

A Phase 0 Trial of Ribociclib in Recurrent Glioblastoma Patients Incorporating a Tumor Pharmacodynamic- and Pharmacokinetic-Guided Expansion Cohort

An-Chi Tien, Jing Li, Xun Bao, Alanna Derogatis, Seongho Kim, Shwetal Mehta, Nader Sanai
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (19): 5777–5786.
https://doi.org/10.1158/1078-0432.CCR-19-0133
Published: 01 October 2019
View article titled, A Phase 0 Trial of Ribociclib in Recurrent Glioblastoma Patients Incorporating a Tumor Pharmacodynamic- and Pharmacokinetic-Guided Expansion Cohort
Open the PDF for A Phase 0 Trial of Ribociclib in Recurrent Glioblastoma Patients Incorporating a Tumor Pharmacodynamic- and Pharmacokinetic-Guided Expansion Cohort in another window
Includes: Supplementary data
Journal Articles

Surufatinib in Advanced Well-Differentiated Neuroendocrine Tumors: A Multicenter, Single-Arm, Open-Label, Phase Ib/II Trial

Jianming Xu, Jie Li, Chunmei Bai, Nong Xu, Zhiwei Zhou, Zhiping Li, Caicun Zhou, Ru Jia, Ming Lu, Yuejuan Cheng, Chenyu Mao, Wei Wang, Ke Cheng, Chunxia Su, Ye Hua, Chuan Qi, Jing Li, Wei Wang, Ke Li, Qiaoling Sun, Yongxin Ren, Weiguo Su
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (12): 3486–3494.
https://doi.org/10.1158/1078-0432.CCR-18-2994
Published: 14 June 2019
View article titled, Surufatinib in Advanced Well-Differentiated Neuroendocrine Tumors: A Multicenter, Single-Arm, Open-Label, Phase Ib/II Trial
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Includes: Supplementary data
Journal Articles

The Reciprocity between Radiotherapy and Cancer Immunotherapy

Yifan Wang, Zhi-Gang Liu, Hengfeng Yuan, Weiye Deng, Jing Li, Yuhui Huang, Betty Y.S. Kim, Michael D. Story, Wen Jiang
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (6): 1709–1717.
https://doi.org/10.1158/1078-0432.CCR-18-2581
Published: 15 March 2019
View article titled, The Reciprocity between Radiotherapy and Cancer Immunotherapy
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Journal Articles

Strategy for Tumor-Selective Disruption of Androgen Receptor Function in the Spectrum of Prostate Cancer

Rayna Rosati, Lisa Polin, Charles Ducker, Jing Li, Xun Bao, Dakshnamurthy Selvakumar, Seongho Kim, Besa Xhabija, Martha Larsen, Thomas McFall, Yanfang Huang, Benjamin L. Kidder, Andrew Fribley, Janice Saxton, Hiroki Kakuta, Peter Shaw, Manohar Ratnam
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (24): 6509–6522.
https://doi.org/10.1158/1078-0432.CCR-18-0982
Published: 13 December 2018
View article titled, Strategy for Tumor-Selective Disruption of Androgen Receptor Function in the Spectrum of Prostate Cancer
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Includes: Supplementary data
Journal Articles

Novel Effector Phenotype of Tim-3+ Regulatory T Cells Leads to Enhanced Suppressive Function in Head and Neck Cancer Patients

Zhuqing Liu, Elizabeth L. McMichael, Gulidanna Shayan, Jing Li, Kevin Chen, Raghvendra Srivastava, Lawrence P. Kane, Binfeng Lu, Robert L. Ferris
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (18): 4529–4538.
https://doi.org/10.1158/1078-0432.CCR-17-1350
Published: 14 September 2018
View article titled, Novel Effector Phenotype of Tim-3<sup>+</sup> Regulatory T Cells Leads to Enhanced Suppressive Function in Head and Neck Cancer Patients
Open the PDF for Novel Effector Phenotype of Tim-3<sup>+</sup> Regulatory T Cells Leads to Enhanced Suppressive Function in Head and Neck Cancer Patients in another window
Includes: Supplementary data
Journal Articles

Phase 0 Trial of AZD1775 in First-Recurrence Glioblastoma Patients

Nader Sanai, Jing Li, Julie Boerner, Karri Stark, Jianmei Wu, Seongho Kim, Alanna Derogatis, Shwetal Mehta, Harshil D. Dhruv, Lance K. Heilbrun, Michael E. Berens, Patricia M. LoRusso
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (16): 3820–3828.
https://doi.org/10.1158/1078-0432.CCR-17-3348
Published: 14 August 2018
View article titled, Phase 0 Trial of AZD1775 in First-Recurrence Glioblastoma Patients
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Includes: Supplementary data
Journal Articles

Quantitative and Mechanistic Understanding of AZD1775 Penetration across Human Blood–Brain Barrier in Glioblastoma Patients Using an IVIVE–PBPK Modeling Approach

Jing Li, Jianmei Wu, Xun Bao, Norissa Honea, Youming Xie, Seongho Kim, Alex Sparreboom, Nader Sanai
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (24): 7454–7466.
https://doi.org/10.1158/1078-0432.CCR-17-0983
Published: 14 December 2017
View article titled, Quantitative and Mechanistic Understanding of AZD1775 Penetration across Human Blood–Brain Barrier in Glioblastoma Patients Using an IVIVE–PBPK Modeling Approach
Open the PDF for Quantitative and Mechanistic Understanding of AZD1775 Penetration across Human Blood–Brain Barrier in Glioblastoma Patients Using an IVIVE–PBPK Modeling Approach in another window
Includes: Supplementary data
Journal Articles

Whole Genomic Copy Number Alterations in Circulating Tumor Cells from Men with Abiraterone or Enzalutamide-Resistant Metastatic Castration-Resistant Prostate Cancer

Santosh Gupta, Jing Li, Gabor Kemeny, Rhonda L. Bitting, Joshua Beaver, Jason A. Somarelli, Kathryn E. Ware, Simon Gregory, Andrew J. Armstrong
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (5): 1346–1357.
https://doi.org/10.1158/1078-0432.CCR-16-1211
Published: 28 February 2017
View article titled, Whole Genomic Copy Number Alterations in Circulating Tumor Cells from Men with Abiraterone or Enzalutamide-Resistant Metastatic Castration-Resistant Prostate Cancer
Open the PDF for Whole Genomic Copy Number Alterations in Circulating Tumor Cells from Men with Abiraterone or Enzalutamide-Resistant Metastatic Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Anti-EGFR Targeted Monoclonal Antibody Isotype Influences Antitumor Cellular Immunity in Head and Neck Cancer Patients

Sumita Trivedi, Raghvendra M. Srivastava, Fernando Concha-Benavente, Soldano Ferrone, Tatiana M. Garcia-Bates, Jing Li, Robert L. Ferris
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (21): 5229–5237.
https://doi.org/10.1158/1078-0432.CCR-15-2971
Published: 31 October 2016
View article titled, Anti-EGFR Targeted Monoclonal Antibody Isotype Influences Antitumor Cellular Immunity in Head and Neck Cancer Patients
Open the PDF for Anti-EGFR Targeted Monoclonal Antibody Isotype Influences Antitumor Cellular Immunity in Head and Neck Cancer Patients in another window
Includes: Supplementary data