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Journal Articles

Germline Mutations of Holliday Junction Resolvase Genes in Multiple Primary Malignancies Involving Lung Cancer Lead to PARP Inhibitor Sensitization

Haoran Wang, Yuping Chen, Xinshu Wang, Binhao Huang, Juntao Xie, Hui Yin, Jie Yang, Jinhuan Wu, Jian Yuan, Jie Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (8): 1607–1618.
https://doi.org/10.1158/1078-0432.CCR-22-3300
Published: 15 April 2024
View article titled, Germline Mutations of Holliday Junction Resolvase Genes in Multiple Primary Malignancies Involving Lung Cancer Lead to PARP Inhibitor Sensitization
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Includes: Supplementary data
Journal Articles

Editor's Note: Cyclin-Dependent Kinase 5 Decreases in Gastric Cancer and its Nuclear Accumulation Suppresses Gastric Tumorigenesis

Longlong Cao, Jiechao Zhou, Junrong Zhang, Sijin Wu, Xintao Yang, Xin Zhao, Huifang Li, Ming Luo, Qian Yu, Guangtan Lin, Huizhong Lin, Jianwei Xie, Ping Li, Xiaoqing Hu, Chaohui Zheng, Guojun Bu, Yun-wu Zhang, Huaxi Xu, Yongliang Yang, Changming Huang, Jie Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (4): 918.
https://doi.org/10.1158/1078-0432.CCR-23-3968
Published: 16 February 2024
View article titled, Editor's Note: Cyclin-Dependent Kinase 5 Decreases in Gastric Cancer and its Nuclear Accumulation Suppresses Gastric Tumorigenesis
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Journal Articles

Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003

Cassie Kline, Payal Jain, Lindsay Kilburn, Erin R. Bonner, Nalin Gupta, John R. Crawford, Anu Banerjee, Roger J. Packer, Javier Villanueva-Meyer, Tracy Luks, Yalan Zhang, Madhuri Kambhampati, Jie Zhang, Sridevi Yadavilli, Bo Zhang, Krutika S. Gaonkar, Jo Lynne Rokita, Adam Kraya, John Kuhn, Winnie Liang, Sara Byron, Michael Berens, Annette Molinaro, Michael Prados, Adam Resnick, Sebastian M. Waszak, Javad Nazarian, Sabine Mueller
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (18): 3965–3978.
https://doi.org/10.1158/1078-0432.CCR-22-0803
Published: 15 September 2022
View article titled, Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003
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Includes: Supplementary data
Journal Articles

Neoadjuvant Trastuzumab and Pyrotinib for Locally Advanced HER2-Positive Breast Cancer (NeoATP): Primary Analysis of a Phase II Study

Wenjin Yin, Yaohui Wang, Ziping Wu, Yumei Ye, Liheng Zhou, Shuguang Xu, Yanping Lin, Yueyao Du, Tingting Yan, Fan Yang, Jie Zhang, Qiang Liu, Jinsong Lu
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (17): 3677–3685.
https://doi.org/10.1158/1078-0432.CCR-22-0446
Published: 01 September 2022
View article titled, Neoadjuvant Trastuzumab and Pyrotinib for Locally Advanced HER2-Positive Breast Cancer (NeoATP): Primary Analysis of a Phase II Study
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Includes: Supplementary data
Journal Articles

Correction: Dual Inhibition of Canonical and Noncanonical NF-κB Pathways Demonstrates Significant Antitumor Activities in Multiple Myeloma

Claire Fabre, Naoya Mimura, Kathryn Bobb, Sun-Young Kong, Güllü Gorgun, Diana Cirstea, Yiguo Hu, Jiro Minami, Hiroto Ohguchi, Jie Zhang, Jeffrey Meshulam, Ruben D. Carrasco, Yu-Tzu Tai, Paul G. Richardson, Teru Hideshima, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (9): 2938.
https://doi.org/10.1158/1078-0432.CCR-19-0959
Published: 01 May 2019
View article titled, Correction: Dual Inhibition of Canonical and Noncanonical NF-κB Pathways Demonstrates Significant Antitumor Activities in Multiple Myeloma
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Journal Articles

Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor Veliparib (ABT-888) in Combination with Irinotecan in Patients with Advanced Solid Tumors

Patricia M. LoRusso, Jing Li, Angelika Burger, Lance K. Heilbrun, Edward A. Sausville, Scott A. Boerner, Daryn Smith, Mary Jo Pilat, Jie Zhang, Sara M. Tolaney, James M. Cleary, Alice P. Chen, Lawrence Rubinstein, Julie L. Boerner, Adam Bowditch, Dongpo Cai, Tracy Bell, Andrew Wolanski, Allison M. Marrero, Yiping Zhang, Jiuping Ji, Katherine Ferry-Galow, Robert J. Kinders, Ralph E. Parchment, Geoffrey I. Shapiro
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (13): 3227–3237.
https://doi.org/10.1158/1078-0432.CCR-15-0652
Published: 30 June 2016
View article titled, Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor Veliparib (ABT-888) in Combination with Irinotecan in Patients with Advanced Solid Tumors
Open the PDF for Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor Veliparib (ABT-888) in Combination with Irinotecan in Patients with Advanced Solid Tumors in another window
Includes: Supplementary data
Journal Articles

Cyclin-Dependent Kinase 5 Decreases in Gastric Cancer and Its Nuclear Accumulation Suppresses Gastric Tumorigenesis

Longlong Cao, Jiechao Zhou, Junrong Zhang, Sijin Wu, Xintao Yang, Xin Zhao, Huifang Li, Ming Luo, Qian Yu, Guangtan Lin, Huizhong Lin, Jianwei Xie, Ping Li, Xiaoqing Hu, Chaohui Zheng, Guojun Bu, Yun-wu Zhang, Huaxi Xu, Yongliang Yang, Changming Huang, Jie Zhang
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2015) 21 (6): 1419–1428.
https://doi.org/10.1158/1078-0432.CCR-14-1950
Published: 12 March 2015
View article titled, Cyclin-Dependent Kinase 5 Decreases in Gastric Cancer and Its Nuclear Accumulation Suppresses Gastric Tumorigenesis
Open the PDF for Cyclin-Dependent Kinase 5 Decreases in Gastric Cancer and Its Nuclear Accumulation Suppresses Gastric Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

FGFR1/3 Tyrosine Kinase Fusions Define a Unique Molecular Subtype of Non–Small Cell Lung Cancer

Rui Wang, Lei Wang, Yuan Li, Haichuan Hu, Lei Shen, Xuxia Shen, Yunjian Pan, Ting Ye, Yang Zhang, Xiaoyang Luo, Yiliang Zhang, Bin Pan, Bin Li, Hang Li, Jie Zhang, William Pao, Hongbin Ji, Yihua Sun, Haiquan Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (15): 4107–4114.
https://doi.org/10.1158/1078-0432.CCR-14-0284
Published: 31 July 2014
View article titled, FGFR1/3 Tyrosine Kinase Fusions Define a Unique Molecular Subtype of Non–Small Cell Lung Cancer
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Includes: Supplementary data
Journal Articles

Dual Inhibition of Canonical and Noncanonical NF-κB Pathways Demonstrates Significant Antitumor Activities in Multiple Myeloma

Claire Fabre, Naoya Mimura, Kathryn Bobb, Sun-Young Kong, Güllü Gorgun, Diana Cirstea, Yiguo Hu, Jiro Minami, Hiroto Ohguchi, Jie Zhang, Jeffrey Meshulam, Ruben D. Carrasco, Yu-Tzu Tai, Paul G. Richardson, Teru Hideshima, Kenneth C. Anderson
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (17): 4669–4681.
https://doi.org/10.1158/1078-0432.CCR-12-0779
Published: 30 August 2012
View article titled, Dual Inhibition of Canonical and Noncanonical NF-κB Pathways Demonstrates Significant Antitumor Activities in Multiple Myeloma
Open the PDF for Dual Inhibition of Canonical and Noncanonical NF-κB Pathways Demonstrates Significant Antitumor Activities in Multiple Myeloma in another window
Includes: Supplementary data
Journal Articles

The Use of Quantitative Real-Time Reverse Transcriptase PCR for 5′ and 3′ Portions of ALK Transcripts to Detect ALK Rearrangements in Lung Cancers

Rui Wang, Yunjian Pan, Chenguang Li, Haichuan Hu, Yang Zhang, Hang Li, Xiaoyang Luo, Jie Zhang, Zhaoyuan Fang, Yuan Li, Lei Shen, Hongbin Ji, David Garfield, Yihua Sun, Haiquan Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (17): 4725–4732.
https://doi.org/10.1158/1078-0432.CCR-12-0677
Published: 30 August 2012
View article titled, The Use of Quantitative Real-Time Reverse Transcriptase PCR for 5′ and 3′ Portions of <em>ALK</em> Transcripts to Detect <em>ALK</em> Rearrangements in Lung Cancers
Open the PDF for The Use of Quantitative Real-Time Reverse Transcriptase PCR for 5′ and 3′ Portions of <em>ALK</em> Transcripts to Detect <em>ALK</em> Rearrangements in Lung Cancers in another window
Includes: Supplementary data
Journal Articles

In vitro and In vivo Radiosensitization of Glioblastoma Cells by the Poly (ADP-Ribose) Polymerase Inhibitor E7016

Andrea L. Russo, Hyuk-Chan Kwon, William E. Burgan, Donna Carter, Katie Beam, Xu Weizheng, Jie Zhang, Barbara S. Slusher, Arnab Chakravarti, Philip J. Tofilon, Kevin Camphausen
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (2): 607–612.
https://doi.org/10.1158/1078-0432.CCR-08-2079
Published: 15 January 2009
View article titled, <em>In vitro</em> and <em>In vivo</em> Radiosensitization of Glioblastoma Cells by the Poly (ADP-Ribose) Polymerase Inhibitor E7016
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Journal Articles

Systemic Administration of GPI 15427, a Novel Poly(ADP-Ribose) Polymerase-1 Inhibitor, Increases the Antitumor Activity of Temozolomide against Intracranial Melanoma, Glioma, Lymphoma

Lucio Tentori, Carlo Leonetti, Marco Scarsella, Giulia d’Amati, Matteo Vergati, Ilaria Portarena, Weizheng Xu, Vincent Kalish, Gabriella Zupi, Jie Zhang, Grazia Graziani
Journal: Clinical Cancer Research
Clin Cancer Res (2003) 9 (14): 5370–5379.
Published: 12 November 2003
View article titled, Systemic Administration of GPI 15427, a Novel Poly(ADP-Ribose) Polymerase-1 Inhibitor, Increases the Antitumor Activity of Temozolomide against Intracranial Melanoma, Glioma, Lymphoma
Open the PDF for Systemic Administration of GPI 15427, a Novel Poly(ADP-Ribose) Polymerase-1 Inhibitor, Increases the Antitumor Activity of Temozolomide against Intracranial Melanoma, Glioma, Lymphoma in another window