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Jianhua Zhang
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Journal Articles

A Modular Trial of Androgen Signaling Inhibitor Combinations Testing a Risk-Adapted Strategy in Patients with Metastatic Castration–Resistant Prostate Cancer

Ana M. Aparicio, Rebecca S.S. Tidwell, Shalini S. Yadav, Jiun-Sheng Chen, Miao Zhang, Jingjing Liu, Shuai Guo, Patrick G. Pilié, Yao Yu, Xingzhi Song, Haswanth Vundavilli, Sonali Jindal, Keyi Zhu, Paul V. Viscuse, Justin M. Lebenthal, Andrew W. Hahn, Rama Soundararajan, Paul G. Corn, Amado Zurita-Saavedra, Sumit K. Subudhi, Jianhua Zhang, Wenyi Wang, Chad Huff, Patricia Troncoso, James P. Allison, Padmanee Sharma, Christopher J. Logothetis
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (13): 2751–2763.
https://doi.org/10.1158/1078-0432.CCR-23-3740
Published: 01 July 2024
View article titled, A Modular Trial of Androgen Signaling Inhibitor Combinations Testing a Risk-Adapted Strategy in Patients with Metastatic Castration–Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Integrative Molecular Analyses of the MD Anderson Prostate Cancer Patient-derived Xenograft (MDA PCa PDX) Series

Nicolas Anselmino, Estefania Labanca, Peter D.A. Shepherd, Jiabin Dong, Jun Yang, Xiaofei Song, Subhiksha Nandakumar, Ritika Kundra, Cindy Lee, Nikolaus Schultz, Jianhua Zhang, John C. Araujo, Ana M. Aparicio, Sumit K. Subudhi, Paul G. Corn, Louis L. Pisters, John F. Ward, John W. Davis, Elba S. Vazquez, Geraldine Gueron, Christopher J. Logothetis, Andrew Futreal, Patricia Troncoso, Yu Chen, Nora M. Navone
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (10): 2272–2285.
https://doi.org/10.1158/1078-0432.CCR-23-2438
Published: 15 May 2024
View article titled, Integrative Molecular Analyses of the MD Anderson Prostate Cancer Patient-derived Xenograft (MDA PCa PDX) Series
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Includes: Supplementary data
Journal Articles

Multi-omics Analysis Reveals Immune Features Associated with Immunotherapy Benefit in Patients with Squamous Cell Lung Cancer from Phase III Lung-MAP S1400I Trial

Edwin Roger Parra, Jiexin Zhang, Dzifa Yawa Duose, Edgar Gonzalez-Kozlova, Mary W. Redman, Hong Chen, Ganiraju C. Manyam, Gayatri Kumar, Jianhua Zhang, Xingzhi Song, Rossana Lazcano, Mario L. Marques-Piubelli, Caddie Laberiano-Fernandez, Frank Rojas, Baili Zhang, Len Taing, Aashna Jhaveri, Jacob Geisberg, Jennifer Altreuter, Franziska Michor, James Provencher, Joyce Yu, Ethan Cerami, Radim Moravec, Kasthuri Kannan, Rajyalakshmi Luthra, Gheath Alatrash, Hsin-Hui Huang, Hui Xie, Manishkumar Patel, Kai Nie, Jocelyn Harris, Kimberly Argueta, James Lindsay, Roshni Biswas, Stephen Van Nostrand, Seunghee Kim-Schulze, Jhanelle E. Gray, Roy S. Herbst, Ignacio I. Wistuba, Scott Gettinger, Karen Kelly, Lyudmila Bazhenova, Sacha Gnjatic, J. Jack Lee, Jianjun Zhang, Cara Haymaker
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (8): 1655–1668.
https://doi.org/10.1158/1078-0432.CCR-23-0251
Published: 15 April 2024
View article titled, Multi-omics Analysis Reveals Immune Features Associated with Immunotherapy Benefit in Patients with Squamous Cell Lung Cancer from Phase III Lung-MAP S1400I Trial
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Includes: Supplementary data
Journal Articles

Correction: Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets

Renata Ferrarotto, Yoshitsugu Mitani, Daniel J. McGrail, Kaiyi Li, Tatiana V. Karpinets, Diana Bell, Steven J. Frank, Xingzhi Song, Michael E. Kupferman, Bin Liu, J. Jack Lee, Bonnie S. Glisson, Jianhua Zhang, Jon C. Aster, Shiaw-Yih Lin, P. Andrew Futreal, John V. Heymach, Adel K. El-Naggar
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (14): 2737.
https://doi.org/10.1158/1078-0432.CCR-23-1697
Published: 14 July 2023
View article titled, Correction: Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets
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Journal Articles

Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets

Renata Ferrarotto, Yoshitsugu Mitani, Daniel J. McGrail, Kaiyi Li, Tatiana V. Karpinets, Diana Bell, Steven J. Frank, Xingzhi Song, Michael E. Kupferman, Bin Liu, J. Jack Lee, Bonnie S. Glisson, Jianhua Zhang, Jon C. Aster, Shiaw-Yih Lin, P. Andrew Futreal, John V. Heymach, Adel K. El-Naggar
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (3): 852–864.
https://doi.org/10.1158/1078-0432.CCR-20-1192
Published: 01 February 2023
View article titled, Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets
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Includes: Supplementary data
Journal Articles

Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma

Andrew W. Hahn, Ashley V. Menk, Dayana B. Rivadeneira, Ryan C. Augustin, Mingchu Xu, Jun Li, Xiaogang Wu, Aditya K. Mishra, Tuba N. Gide, Camelia Quek, Yan Zang, Christine N. Spencer, Alexander M. Menzies, Carrie R. Daniel, Courtney W. Hudgens, Theodore Nowicki, Lauren E. Haydu, M.A. Wadud Khan, Vancheswaran Gopalakrishnan, Elizabeth M. Burton, Jared Malke, Julie M. Simon, Chantale Bernatchez, Nagireddy Putluri, Scott E. Woodman, Y.N. Vashisht Gopal, Renato Guerrieri, Grant M. Fischer, Jian Wang, Khalida M. Wani, John F. Thompson, Jeffrey E. Lee, Patrick Hwu, Nadim Ajami, Jeffrey E. Gershenwald, Georgina V. Long, Richard A. Scolyer, Michael T. Tetzlaff, Alexander J. Lazar, Dirk Schadendorf, Jennifer A. Wargo, John M. Kirkwood, Ralph J. DeBerardinis, Han Liang, Andrew Futreal, Jianhua Zhang, James S. Wilmott, Weiyi Peng, Michael A. Davies, Greg M. Delgoffe, Yana G. Najjar, Jennifer L. McQuade
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (1): 154–164.
https://doi.org/10.1158/1078-0432.CCR-22-2661
Published: 04 January 2023
View article titled, Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma
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Includes: Supplementary data
Journal Articles

Genomic Correlates of Outcome in Tumor-Infiltrating Lymphocyte Therapy for Metastatic Melanoma

Caitlin A. Creasy, Yuzhong Jeff Meng, Marie-Andrée Forget, Tatiana Karpinets, Katarzyna Tomczak, Chip Stewart, Carlos A. Torres-Cabala, Shari Pilon-Thomas, Amod A. Sarnaik, James J. Mulé, Levi Garraway, Matias Bustos, Jianhua Zhang, Sapna P. Patel, Adi Diab, Isabella C. Glitza, Cassian Yee, Hussein Tawbi, Michael K. Wong, Jennifer McQuade, Dave S.B. Hoon, Michael A. Davies, Patrick Hwu, Rodabe N. Amaria, Cara Haymaker, Rameen Beroukhim, Chantale Bernatchez
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (9): 1911–1924.
https://doi.org/10.1158/1078-0432.CCR-21-1060
Published: 02 May 2022
View article titled, Genomic Correlates of Outcome in Tumor-Infiltrating Lymphocyte Therapy for Metastatic Melanoma
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Includes: Supplementary data
Journal Articles

Cross-Site Concordance Evaluation of Tumor DNA and RNA Sequencing Platforms for the CIMAC-CIDC Network

Zexian Zeng, Jingxin Fu, Carrie Cibulskis, Aashna Jhaveri, Curtis Gumbs, Biswajit Das, Beatriz Sanchez-Espiridion, Sylvie Janssens, Len Taing, Jin Wang, James Lindsay, Tomas Vilimas, Jianhua Zhang, Collin Tokheim, Avinash Sahu, Peng Jiang, Chunhua Yan, Dzifa Yawa Duose, Ethan Cerami, Li Chen, David Cohen, Qingrong Chen, Rebecca Enos, Xin Huang, Jack J. Lee, Yang Liu, Donna S. Neuberg, Cu Nguyen, Candace Patterson, Sharmistha Sarkar, Sachet Shukla, Ming Tang, Junko Tsuji, Mohamed Uduman, Xiaoman Wang, Jason L. Weirather, Jijun Yu, Joyce Yu, Jianjun Zhang, Jiexin Zhang, Daoud Meerzaman, Magdalena Thurin, Andrew Futreal, Chris Karlovich, Stacey B. Gabriel, Ignacio Ivan Wistuba, X. Shirley Liu, Catherine J. Wu
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (18): 5049–5061.
https://doi.org/10.1158/1078-0432.CCR-20-3251
Published: 15 September 2021
View article titled, Cross-Site Concordance Evaluation of Tumor DNA and RNA Sequencing Platforms for the CIMAC-CIDC Network
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Includes: Supplementary data
Journal Articles

Whole-Genome Sequencing of Common Salivary Gland Carcinomas: Subtype-Restricted and Shared Genetic Alterations

Tatiana V. Karpinets, Yoshitsugu Mitani, Bin Liu, Jianhua Zhang, Kristen B. Pytynia, Linton D. Sellen, Danice T. Karagiannis, Renata Ferrarotto, Andrew P. Futreal, Adel K. El-Naggar
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (14): 3960–3969.
https://doi.org/10.1158/1078-0432.CCR-20-4071
Published: 15 July 2021
View article titled, Whole-Genome Sequencing of Common Salivary Gland Carcinomas: Subtype-Restricted and Shared Genetic Alterations
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Includes: Supplementary data
Journal Articles

Evolution of Genomic and T-cell Repertoire Heterogeneity of Malignant Pleural Mesothelioma Under Dasatinib Treatment

Runzhe Chen, Won-Chul Lee, Junya Fujimoto, Jun Li, Xin Hu, Reza Mehran, David Rice, Stephen G. Swisher, Boris Sepesi, Hai T. Tran, Chi-Wan Chow, Latasha D. Little, Curtis Gumbs, Cara Haymaker, John V. Heymach, Ignacio I. Wistuba, J. Jack Lee, P. Andrew Futreal, Jianhua Zhang, Alexandre Reuben, Anne S. Tsao, Jianjun Zhang
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (20): 5477–5486.
https://doi.org/10.1158/1078-0432.CCR-20-1767
Published: 15 October 2020
View article titled, Evolution of Genomic and T-cell Repertoire Heterogeneity of Malignant Pleural Mesothelioma Under Dasatinib Treatment
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Includes: Supplementary data
Journal Articles

Abstract 16: Genomic landscape of adult mixed phenotype acute leukemia (MPAL)

Koichi Takahashi, Feng Wang, Kiyomi Morita, Keyur Patel, Carlos Bueso-Ramos, Abdallah Abou Zahr, Curtis Gumbs, Latasha Little, Samantha Tippen, Rebecca Thornton, Marcus Coyle, Jianhua Zhang, Xingzhi Song, Marisela Mendoza, Chang-Jiu Wu, Steven Kornblau, Courtney DiNardo, Guillermo Garcia-Manero, Elias Jabbour, Michael Andreeff, Farhad Ravandi, Hagop Kantarjian, Jorge Cortes, Marina Konopleva, Andrew Futreal
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (24_Supplement): 16.
https://doi.org/10.1158/1557-3265.HEMMAL17-16
Published: 14 December 2017
View article titled, Abstract 16: Genomic landscape of adult mixed phenotype acute leukemia (MPAL)
Journal Articles

4-1BB Agonist Focuses CD8+ Tumor-Infiltrating T-Cell Growth into a Distinct Repertoire Capable of Tumor Recognition in Pancreatic Cancer

Donastas Sakellariou-Thompson, Marie-Andrée Forget, Caitlin Creasy, Vincent Bernard, Li Zhao, Young Uk Kim, Mark W. Hurd, Naohiro Uraoka, Edwin Roger Parra, Ya'an Kang, Christopher A. Bristow, Jaime Rodriguez-Canales, Jason B. Fleming, Gauri Varadhachary, Milind Javle, Michael J. Overman, Hector A. Alvarez, Timothy P. Heffernan, Jianhua Zhang, Patrick Hwu, Anirban Maitra, Cara Haymaker, Chantale Bernatchez
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (23): 7263–7275.
https://doi.org/10.1158/1078-0432.CCR-17-0831
Published: 30 November 2017
View article titled, 4-1BB Agonist Focuses CD8<sup>+</sup> Tumor-Infiltrating T-Cell Growth into a Distinct Repertoire Capable of Tumor Recognition in Pancreatic Cancer
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Includes: Supplementary data
Journal Articles

Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma

Curtis R. Pickering, Jane H. Zhou, J. Jack Lee, Jennifer A. Drummond, S. Andrew Peng, Rami E. Saade, Kenneth Y. Tsai, Jonathan L. Curry, Michael T. Tetzlaff, Stephen Y. Lai, Jun Yu, Donna M. Muzny, Harshavardhan Doddapaneni, Eve Shinbrot, Kyle R. Covington, Jianhua Zhang, Sahil Seth, Carlos Caulin, Gary L. Clayman, Adel K. El-Naggar, Richard A. Gibbs, Randal S. Weber, Jeffrey N. Myers, David A. Wheeler, Mitchell J. Frederick
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (24): 6582–6592.
https://doi.org/10.1158/1078-0432.CCR-14-1768
Published: 14 December 2014
View article titled, Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma
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Includes: Supplementary data