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Jianhua Yu
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Journal Articles

NOTCH-Induced MDSC Recruitment after oHSV Virotherapy in CNS Cancer Models Modulates Antitumor Immunotherapy

Yoshihiro Otani, Ji Young Yoo, Cole T. Lewis, Samantha Chao, Jessica Swanner, Toshihiko Shimizu, Jin Muk Kang, Sara A. Murphy, Kimberly Rivera-Caraballo, Bangxing Hong, Joseph C. Glorioso, Hiroshi Nakashima, Sean E. Lawler, Yeshavanth Banasavadi-Siddegowda, John D. Heiss, Yuanqing Yan, Guangsheng Pei, Michael A. Caligiuri, Zhongming Zhao, E. Antonio Chiocca, Jianhua Yu, Balveen Kaur
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (7): 1460–1473.
https://doi.org/10.1158/1078-0432.CCR-21-2347
Published: 01 April 2022
View article titled, NOTCH-Induced MDSC Recruitment after oHSV Virotherapy in CNS Cancer Models Modulates Antitumor Immunotherapy
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Includes: Supplementary data
Journal Articles

Targeting Fc Receptor-Mediated Effects and the “Don't Eat Me” Signal with an Oncolytic Virus Expressing an Anti-CD47 Antibody to Treat Metastatic Ovarian Cancer

Lei Tian, Bo Xu, Kun-Yu Teng, Mihae Song, Zheng Zhu, Yuqing Chen, Jing Wang, Jianying Zhang, Mingye Feng, Balveen Kaur, Lorna Rodriguez, Michael A. Caligiuri, Jianhua Yu
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (1): 201–214.
https://doi.org/10.1158/1078-0432.CCR-21-1248
Published: 05 January 2022
View article titled, Targeting Fc Receptor-Mediated Effects and the “Don't Eat Me” Signal with an Oncolytic Virus Expressing an Anti-CD47 Antibody to Treat Metastatic Ovarian Cancer
Open the PDF for Targeting Fc Receptor-Mediated Effects and the “Don't Eat Me” Signal with an Oncolytic Virus Expressing an Anti-CD47 Antibody to Treat Metastatic Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Oncolytic HSV–Infected Glioma Cells Activate NOTCH in Adjacent Tumor Cells Sensitizing Tumors to Gamma Secretase Inhibition

Yoshihiro Otani, Ji Young Yoo, Samantha Chao, Joseph Liu, Alena Cristina Jaime-Ramirez, Tae Jin Lee, Brian Hurwitz, Yuanqing Yan, Hongsheng Dai, Joseph C. Glorioso, Michael A. Caligiuri, Jianhua Yu, Balveen Kaur
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (10): 2381–2392.
https://doi.org/10.1158/1078-0432.CCR-19-3420
Published: 15 May 2020
View article titled, Oncolytic HSV–Infected Glioma Cells Activate NOTCH in Adjacent Tumor Cells Sensitizing Tumors to Gamma Secretase Inhibition
Open the PDF for Oncolytic HSV–Infected Glioma Cells Activate NOTCH in Adjacent Tumor Cells Sensitizing Tumors to Gamma Secretase Inhibition in another window
Includes: Supplementary data
Journal Articles

Fratricide of NK Cells in Daratumumab Therapy for Multiple Myeloma Overcome by Ex Vivo–Expanded Autologous NK Cells

Yufeng Wang, Yibo Zhang, Tiffany Hughes, Jianying Zhang, Michael A. Caligiuri, Don M. Benson, Jianhua Yu
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (16): 4006–4017.
https://doi.org/10.1158/1078-0432.CCR-17-3117
Published: 14 August 2018
View article titled, Fratricide of NK Cells in Daratumumab Therapy for Multiple Myeloma Overcome by <em>Ex Vivo</em>–Expanded Autologous NK Cells
Open the PDF for Fratricide of NK Cells in Daratumumab Therapy for Multiple Myeloma Overcome by <em>Ex Vivo</em>–Expanded Autologous NK Cells in another window
Includes: Supplementary data
Journal Articles

BAI1 Orchestrates Macrophage Inflammatory Response to HSV Infection—Implications for Oncolytic Viral Therapy

Chelsea Bolyard, W. Hans Meisen, Yeshavanth Banasavadi-Siddegowda, Jayson Hardcastle, Ji Young Yoo, Eric S. Wohleb, Jeffrey Wojton, Jun-Ge Yu, Samuel Dubin, Maninder Khosla, Bo Xu, Jonathan Smith, Christopher Alvarez-Breckenridge, Pete Pow-anpongkul, Flavia Pichiorri, Jianying Zhang, Matthew Old, Dan Zhu, Erwin G. Van Meir, Jonathan P. Godbout, Michael A. Caligiuri, Jianhua Yu, Balveen Kaur
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (7): 1809–1819.
https://doi.org/10.1158/1078-0432.CCR-16-1818
Published: 02 April 2017
View article titled, BAI1 Orchestrates Macrophage Inflammatory Response to HSV Infection—Implications for Oncolytic Viral Therapy
Open the PDF for BAI1 Orchestrates Macrophage Inflammatory Response to HSV Infection—Implications for Oncolytic Viral Therapy in another window
Includes: Supplementary data
Journal Articles

Bortezomib Treatment Sensitizes Oncolytic HSV-1–Treated Tumors to NK Cell Immunotherapy

Ji Young Yoo, Alena Cristina Jaime-Ramirez, Chelsea Bolyard, Hongsheng Dai, Tejaswini Nallanagulagari, Jeffrey Wojton, Brian S. Hurwitz, Theresa Relation, Tae Jin Lee, Michael T. Lotze, Jun-Ge Yu, Jianying Zhang, Carlo M. Croce, Jianhua Yu, Michael A. Caligiuri, Matthew Old, Balveen Kaur
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (21): 5265–5276.
https://doi.org/10.1158/1078-0432.CCR-16-1003
Published: 31 October 2016
View article titled, Bortezomib Treatment Sensitizes Oncolytic HSV-1–Treated Tumors to NK Cell Immunotherapy
Open the PDF for Bortezomib Treatment Sensitizes Oncolytic HSV-1–Treated Tumors to NK Cell Immunotherapy in another window
Includes: Supplementary data
Journal Articles

The Impact of Macrophage- and Microglia-Secreted TNFα on Oncolytic HSV-1 Therapy in the Glioblastoma Tumor Microenvironment

W. Hans Meisen, Eric S. Wohleb, Alena Cristina Jaime-Ramirez, Chelsea Bolyard, Ji Young Yoo, Luke Russell, Jayson Hardcastle, Samuel Dubin, Kamaldeen Muili, Jianhua Yu, Michael Caligiuri, Jonathan Godbout, Balveen Kaur
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (14): 3274–3285.
https://doi.org/10.1158/1078-0432.CCR-14-3118
Published: 14 July 2015
View article titled, The Impact of Macrophage- and Microglia-Secreted TNFα on Oncolytic HSV-1 Therapy in the Glioblastoma Tumor Microenvironment
Open the PDF for The Impact of Macrophage- and Microglia-Secreted TNFα on Oncolytic HSV-1 Therapy in the Glioblastoma Tumor Microenvironment in another window
Includes: Supplementary data
Journal Articles

Genetic Modification of T Cells Redirected toward CS1 Enhances Eradication of Myeloma Cells

Jianhong Chu, Shun He, Youcai Deng, Jianying Zhang, Yong Peng, Tiffany Hughes, Ling Yi, Chang-Hyuk Kwon, Qi-En Wang, Steven M. Devine, Xiaoming He, Xue-Feng Bai, Craig C. Hofmeister, Jianhua Yu
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (15): 3989–4000.
https://doi.org/10.1158/1078-0432.CCR-13-2510
Published: 31 July 2014
View article titled, Genetic Modification of T Cells Redirected toward CS1 Enhances Eradication of Myeloma Cells
Open the PDF for Genetic Modification of T Cells Redirected toward CS1 Enhances Eradication of Myeloma Cells in another window
Includes: Supplementary data
Journal Articles

Bortezomib-Induced Unfolded Protein Response Increases Oncolytic HSV-1 Replication Resulting in Synergistic Antitumor Effects

Ji Young Yoo, Brian S. Hurwitz, Chelsea Bolyard, Jun-Ge Yu, Jianying Zhang, Karuppaiyah Selvendiran, Kellie S. Rath, Shun He, Zachary Bailey, David Eaves, Timothy P. Cripe, Deborah S. Parris, Michael A. Caligiuri, Jianhua Yu, Matthew Old, Balveen Kaur
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (14): 3787–3798.
https://doi.org/10.1158/1078-0432.CCR-14-0553
Published: 14 July 2014
View article titled, Bortezomib-Induced Unfolded Protein Response Increases Oncolytic HSV-1 Replication Resulting in Synergistic Antitumor Effects
Open the PDF for Bortezomib-Induced Unfolded Protein Response Increases Oncolytic HSV-1 Replication Resulting in Synergistic Antitumor Effects in another window
Includes: Supplementary data