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Journal Articles

Personalized MRD Assessment in Perisurgical ctDNA for Prognostic Prediction in Hepatocellular Carcinoma

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Jie Hu, Haoran Tang, Can-Can Jia, Xiang-Yu Zhang, Ying Xu, Jin-Peng Tan, Jia Fan, Shidong Jia, Jian Zhou
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (6): 1047–1056.
https://doi.org/10.1158/1078-0432.CCR-24-1897
Published: 17 March 2025
View article titled, Personalized MRD Assessment in Perisurgical ctDNA for Prognostic Prediction in Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Correction: PRMT5 Circular RNA Promotes Metastasis of Urothelial Carcinoma of the Bladder through Sponging miR-30c to Induce Epithelial–Mesenchymal Transition

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Xin Chen, Ri-Xin Chen, Wen-Su Wei, Yong-Hong Li, Zi-Hao Feng, Lei Tan, Jie-Wei Chen, Gang-Jun Yuan, Si-Liang Chen, Sheng-Jie Guo, Kang-Hua Xiao, Zhuo-Wei Liu, Jun-Hang Luo, Fang-Jian Zhou, Dan Xie
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (9): 2664.
https://doi.org/10.1158/1078-0432.CCR-21-0936
Published: 01 May 2021
View article titled, Correction: PRMT5 Circular RNA Promotes Metastasis of Urothelial Carcinoma of the Bladder through Sponging miR-30c to Induce Epithelial–Mesenchymal Transition
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Journal Articles

Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma

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Jian Zhou, Francisco Sanchez-Vega, Raul Caso, Kay See Tan, Whitney S. Brandt, Gregory D. Jones, Shi Yan, Prasad S. Adusumilli, Matthew Bott, James Huang, James M. Isbell, Smita Sihag, Daniela Molena, Valerie W. Rusch, Walid K. Chatila, Natasha Rekhtman, Fan Yang, Marc Ladanyi, David B. Solit, Michael F. Berger, Nikolaus Schultz, David R. Jones
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (24): 7475–7484.
https://doi.org/10.1158/1078-0432.CCR-19-1651
Published: 13 December 2019
View article titled, Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma
Open the PDF for Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma in another window
Includes: Supplementary data
Journal Articles

Activated and Exhausted MAIT Cells Foster Disease Progression and Indicate Poor Outcome in Hepatocellular Carcinoma

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Meng Duan, Shyamal Goswami, Jie-Yi Shi, Lin-Jie Wu, Xiao-Ying Wang, Jia-Qiang Ma, Zhao Zhang, Yang Shi, Li-Jie Ma, Shu Zhang, Rui-Bin Xi, Ya Cao, Jian Zhou, Jia Fan, Xiao-Ming Zhang, Qiang Gao
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (11): 3304–3316.
https://doi.org/10.1158/1078-0432.CCR-18-3040
Published: 03 June 2019
View article titled, Activated and Exhausted MAIT Cells Foster Disease Progression and Indicate Poor Outcome in Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

PRMT5 Circular RNA Promotes Metastasis of Urothelial Carcinoma of the Bladder through Sponging miR-30c to Induce Epithelial–Mesenchymal Transition

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Xin Chen, Ri-Xin Chen, Wen-Su Wei, Yong-Hong Li, Zi-Hao Feng, Lei Tan, Jie-Wei Chen, Gang-Jun Yuan, Si-Liang Chen, Sheng-Jie Guo, Kang-Hua Xiao, Zhuo-Wei Liu, Jun-Hang Luo, Fang-Jian Zhou, Dan Xie
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (24): 6319–6330.
https://doi.org/10.1158/1078-0432.CCR-18-1270
Published: 13 December 2018
View article titled, PRMT5 Circular RNA Promotes Metastasis of Urothelial Carcinoma of the Bladder through Sponging miR-30c to Induce Epithelial–Mesenchymal Transition
Open the PDF for PRMT5 Circular RNA Promotes Metastasis of Urothelial Carcinoma of the Bladder through Sponging miR-30c to Induce Epithelial–Mesenchymal Transition in another window
Includes: Supplementary data
Journal Articles

Adjuvant Transarterial Chemoembolization for HBV-Related Hepatocellular Carcinoma After Resection: A Randomized Controlled Study

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Zheng Wang, Zhenggang Ren, Yi Chen, Jie Hu, Guohuan Yang, Lei Yu, Xinrong Yang, Ao Huang, Xin Zhang, Shaolai Zhou, Huichuan Sun, Yanhong Wang, Ningling Ge, Xiaoyu Xu, Zhaoyou Tang, Wanyee Lau, Jia Fan, Jiping Wang, Jian Zhou
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (9): 2074–2081.
https://doi.org/10.1158/1078-0432.CCR-17-2899
Published: 30 April 2018
View article titled, Adjuvant Transarterial Chemoembolization for HBV-Related Hepatocellular Carcinoma After Resection: A Randomized Controlled Study
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Includes: Supplementary data
Journal Articles

Circulating Tumor Cells with Stem-Like Phenotypes for Diagnosis, Prognosis, and Therapeutic Response Evaluation in Hepatocellular Carcinoma

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Wei Guo, Yun-Fan Sun, Min-Na Shen, Xiao-Lu Ma, Jiong Wu, Chun-Yan Zhang, Yan Zhou, Yang Xu, Bo Hu, Min Zhang, Gang Wang, Wei-Qin Chen, Lin Guo, Ren-Quan Lu, Chao-Hui Zhou, Xin Zhang, Ying-Hong Shi, Shuang-jian Qiu, Bai-shen Pan, Ya Cao, Jian Zhou, Xin-Rong Yang, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (9): 2203–2213.
https://doi.org/10.1158/1078-0432.CCR-17-1753
Published: 30 April 2018
View article titled, Circulating Tumor Cells with Stem-Like Phenotypes for Diagnosis, Prognosis, and Therapeutic Response Evaluation in Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Circulating Tumor Cells from Different Vascular Sites Exhibit Spatial Heterogeneity in Epithelial and Mesenchymal Composition and Distinct Clinical Significance in Hepatocellular Carcinoma

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Yun-Fan Sun, Wei Guo, Yang Xu, Yin-Hong Shi, Zi-Jun Gong, Yuan Ji, Min Du, Xin Zhang, Bo Hu, Ao Huang, George G. Chen, Paul B.S. Lai, Ya Cao, Shuang-Jian Qiu, Jian Zhou, Xin-Rong Yang, Jia Fan
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (3): 547–559.
https://doi.org/10.1158/1078-0432.CCR-17-1063
Published: 31 January 2018
View article titled, Circulating Tumor Cells from Different Vascular Sites Exhibit Spatial Heterogeneity in Epithelial and Mesenchymal Composition and Distinct Clinical Significance in Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Systemic Immune-Inflammation Index Predicts Prognosis of Patients after Curative Resection for Hepatocellular Carcinoma

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Bo Hu, Xin-Rong Yang, Yang Xu, Yun-Fan Sun, Chao Sun, Wei Guo, Xin Zhang, Wei-Min Wang, Shuang-Jian Qiu, Jian Zhou, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (23): 6212–6222.
https://doi.org/10.1158/1078-0432.CCR-14-0442
Published: 30 November 2014
View article titled, Systemic Immune-Inflammation Index Predicts Prognosis of Patients after Curative Resection for Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Clinical Significance of EpCAM mRNA-Positive Circulating Tumor Cells in Hepatocellular Carcinoma by an Optimized Negative Enrichment and qRT-PCR–Based Platform

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Wei Guo, Xin-Rong Yang, Yun-Fan Sun, Min-Na Shen, Xiao-Lu Ma, Jiong Wu, Chun-Yan Zhang, Yan Zhou, Yang Xu, Bo Hu, Xin Zhang, Jian Zhou, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (18): 4794–4805.
https://doi.org/10.1158/1078-0432.CCR-14-0251
Published: 14 September 2014
View article titled, Clinical Significance of EpCAM mRNA-Positive Circulating Tumor Cells in Hepatocellular Carcinoma by an Optimized Negative Enrichment and qRT-PCR–Based Platform
Open the PDF for Clinical Significance of EpCAM mRNA-Positive Circulating Tumor Cells in Hepatocellular Carcinoma by an Optimized Negative Enrichment and qRT-PCR–Based Platform in another window
Includes: Supplementary data
Journal Articles

Margin-Infiltrating CD20+ B Cells Display an Atypical Memory Phenotype and Correlate with Favorable Prognosis in Hepatocellular Carcinoma

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Jie-Yi Shi, Qiang Gao, Zhi-Chao Wang, Jian Zhou, Xiao-Ying Wang, Zhi-Hui Min, Ying-Hong Shi, Guo-Ming Shi, Zhen-Bin Ding, Ai-Wu Ke, Zhi Dai, Shuang-Jian Qiu, Kang Song, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (21): 5994–6005.
https://doi.org/10.1158/1078-0432.CCR-12-3497
Published: 31 October 2013
View article titled, Margin-Infiltrating CD20+ B Cells Display an Atypical Memory Phenotype and Correlate with Favorable Prognosis in Hepatocellular Carcinoma
Open the PDF for Margin-Infiltrating CD20+ B Cells Display an Atypical Memory Phenotype and Correlate with Favorable Prognosis in Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

ERG Rearrangement for Predicting Subsequent Cancer Diagnosis in High-Grade Prostatic Intraepithelial Neoplasia and Lymph Node Metastasis

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Xin Gao, Liao-Yuan Li, Fang-Jian Zhou, Ke-Ji Xie, Chun-Kui Shao, Zu-Lan Su, Qi-Peng Sun, Ming-Kun Chen, Jun Pang, Xiang-Fu Zhou, Jian-Guang Qiu, Xing-Qiao Wen, Ming Yang, Xian-Zhong Bai, Hao Zhang, Li Ling, Zhong Chen
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (15): 4163–4172.
https://doi.org/10.1158/1078-0432.CCR-11-2449
Published: 30 July 2012
View article titled, ERG Rearrangement for Predicting Subsequent Cancer Diagnosis in High-Grade Prostatic Intraepithelial Neoplasia and Lymph Node Metastasis
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Journal Articles

Decreased Selenium-Binding Protein 1 Enhances Glutathione Peroxidase 1 Activity and Downregulates HIF-1α to Promote Hepatocellular Carcinoma Invasiveness

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Cheng Huang, Guangyu Ding, Chengyu Gu, Jian Zhou, Ming Kuang, Yuan Ji, Yifeng He, Tadashi Kondo, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (11): 3042–3053.
https://doi.org/10.1158/1078-0432.CCR-12-0183
Published: 31 May 2012
View article titled, Decreased Selenium-Binding Protein 1 Enhances Glutathione Peroxidase 1 Activity and Downregulates HIF-1α to Promote Hepatocellular Carcinoma Invasiveness
Open the PDF for Decreased Selenium-Binding Protein 1 Enhances Glutathione Peroxidase 1 Activity and Downregulates HIF-1α to Promote Hepatocellular Carcinoma Invasiveness in another window
Includes: Supplementary data
Journal Articles

Metadherin Promotes Hepatocellular Carcinoma Metastasis through Induction of Epithelial–Mesenchymal Transition

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Kai Zhu, Zhi Dai, Qi Pan, Zheng Wang, Guo-Huan Yang, Lei Yu, Zhen-Bin Ding, Guo-Ming Shi, Ai-Wu Ke, Xin-Rong Yang, Zhong-Hua Tao, Yi-Ming Zhao, Yi Qin, Hai-Ying Zeng, Zhao-You Tang, Jia Fan, Jian Zhou
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (23): 7294–7302.
https://doi.org/10.1158/1078-0432.CCR-11-1327
Published: 30 November 2011
View article titled, Metadherin Promotes Hepatocellular Carcinoma Metastasis through Induction of Epithelial–Mesenchymal Transition
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Includes: Supplementary data
Journal Articles

Autophagy Activation in Hepatocellular Carcinoma Contributes to the Tolerance of Oxaliplatin via Reactive Oxygen Species Modulation

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Zhen-Bin Ding, Bo Hui, Ying-Hong Shi, Jian Zhou, Yuan-Fei Peng, Cheng-Yu Gu, Hua Yang, Guo-Ming Shi, Ai-Wu Ke, Xiao-Ying Wang, Kang Song, Zhi Dai, Ying-Hao Shen, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (19): 6229–6238.
https://doi.org/10.1158/1078-0432.CCR-11-0816
Published: 02 October 2011
View article titled, Autophagy Activation in Hepatocellular Carcinoma Contributes to the Tolerance of Oxaliplatin via Reactive Oxygen Species Modulation
Open the PDF for Autophagy Activation in Hepatocellular Carcinoma Contributes to the Tolerance of Oxaliplatin via Reactive Oxygen Species Modulation in another window
Includes: Supplementary data
Journal Articles

CD24 Is a Novel Predictor for Poor Prognosis of Hepatocellular Carcinoma after Surgery

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Xin-Rong Yang, Yang Xu, Bin Yu, Jian Zhou, Jia-Chu Li, Shuang-Jian Qiu, Ying-Hong Shi, Xiao-Ying Wang, Zhi Dai, Guo-Ming Shi, Bin Wu, Li-Ming Wu, Guo-Huan Yang, Bo-Heng Zhang, Wen-Xin Qin, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (17): 5518–5527.
https://doi.org/10.1158/1078-0432.CCR-09-0151
Published: 31 August 2009
View article titled, CD24 Is a Novel Predictor for Poor Prognosis of Hepatocellular Carcinoma after Surgery
Open the PDF for CD24 Is a Novel Predictor for Poor Prognosis of Hepatocellular Carcinoma after Surgery in another window
Includes: Supplementary data
Journal Articles

Human Leukocyte Antigen-G Protein Expression Is an Unfavorable Prognostic Predictor of Hepatocellular Carcinoma following Curative Resection

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Ming-Yan Cai, Yong-Feng Xu, Shuang-Jian Qiu, Min-Jie Ju, Qiang Gao, Yi-Wei Li, Bo-Heng Zhang, Jian Zhou, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (14): 4686–4693.
https://doi.org/10.1158/1078-0432.CCR-09-0463
Published: 15 July 2009
View article titled, Human Leukocyte Antigen-G Protein Expression Is an Unfavorable Prognostic Predictor of Hepatocellular Carcinoma following Curative Resection
Open the PDF for Human Leukocyte Antigen-G Protein Expression Is an Unfavorable Prognostic Predictor of Hepatocellular Carcinoma following Curative Resection in another window
Includes: Supplementary data
Journal Articles

Overexpression of PD-L1 Significantly Associates with Tumor Aggressiveness and Postoperative Recurrence in Human Hepatocellular Carcinoma

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Qiang Gao, Xiao-Ying Wang, Shuang-Jian Qiu, Ichiro Yamato, Masayuki Sho, Yoshiyuki Nakajima, Jian Zhou, Bai-Zhou Li, Ying-Hong Shi, Yong-Sheng Xiao, Yang Xu, Jia Fan
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (3): 971–979.
https://doi.org/10.1158/1078-0432.CCR-08-1608
Published: 02 February 2009
View article titled, Overexpression of PD-L1 Significantly Associates with Tumor Aggressiveness and Postoperative Recurrence in Human Hepatocellular Carcinoma
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Includes: Supplementary data
Journal Articles

Effect of Rapamycin Alone and in Combination with Sorafenib in an Orthotopic Model of Human Hepatocellular Carcinoma

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Zheng Wang, Jian Zhou, Jia Fan, Shuang-Jian Qiu, Yao Yu, Xiao-Wu Huang, Zhao-You Tang
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (16): 5124–5130.
https://doi.org/10.1158/1078-0432.CCR-07-4774
Published: 12 August 2008
View article titled, Effect of Rapamycin Alone and in Combination with Sorafenib in an Orthotopic Model of Human Hepatocellular Carcinoma
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Journal Articles

Cytokeratin 10 and Cytokeratin 19: Predictive Markers for Poor Prognosis in Hepatocellular Carcinoma Patients after Curative Resection

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Xin-Rong Yang, Yang Xu, Guo-Ming Shi, Jia Fan, Jian Zhou, Yuan Ji, Hui-Chuan Sun, Shuang-Jian Qiu, Bing Yu, Qiang Gao, Yi-Zhou He, Weng-Zhen Qin, Rong-Xin Chen, Guo-Huan Yang, Bing Wu, Qing Lu, Zhi-Quan Wu, Zhao-You Tang
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (12): 3850–3859.
https://doi.org/10.1158/1078-0432.CCR-07-4338
Published: 16 June 2008
View article titled, Cytokeratin 10 and Cytokeratin 19: Predictive Markers for Poor Prognosis in Hepatocellular Carcinoma Patients after Curative Resection
Open the PDF for Cytokeratin 10 and Cytokeratin 19: Predictive Markers for Poor Prognosis in Hepatocellular Carcinoma Patients after Curative Resection in another window