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Jessica K. Lee
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Journal Articles

RAS/RAF Comutation and ERBB2 Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer

Harshabad Singh, Pranshu Sahgal, Kevin Kapner, Steven M. Corsello, Hersh Gupta, Rahul Gujrathi, Yvonne Y. Li, Andrew D. Cherniack, Raquelle El Alam, Joseph Kerfoot, Elizabeth Andrews, Annette Lee, Chetan Nambiar, Alison M. Hannigan, Joshua Remland, Lauren Brais, Meghan E. Leahy, Douglas A. Rubinson, Benjamin L. Schlechter, Matthew Meyerson, Yanan Kuang, Cloud P. Paweletz, Jessica K. Lee, Julia C.F. Quintanilha, Andrew J. Aguirre, Kimberly J. Perez, Brandon M. Huffman, Humberto Rossi, Thomas A. Abrams, Sheheryar Kabraji, Livio Trusolino, Andrea Bertotti, Ewa T. Sicinska, Aparna R. Parikh, Brian M. Wolpin, Alexa B. Schrock, Marios Giannakis, Kimmie Ng, Jeffrey A. Meyerhardt, Jason L. Hornick, Nilay S. Sethi, James M. Cleary
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (8): 1669–1684.
https://doi.org/10.1158/1078-0432.CCR-23-2581
Published: 15 April 2024
View article titled, <em>RAS/RAF</em> Comutation and <em>ERBB2</em> Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer
Open the PDF for <em>RAS/RAF</em> Comutation and <em>ERBB2</em> Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Circulating Tumor DNA Enables Sensitive Detection of Actionable Gene Fusions and Rearrangements Across Cancer Types

Pashtoon M. Kasi, Jessica K. Lee, Lincoln W. Pasquina, Brennan Decker, Pierre Vanden Borre, Dean C. Pavlick, Justin M. Allen, Christine Parachoniak, Julia C. F. Quintanilha, Ryon P. Graf, Alexa B. Schrock, Geoffrey R. Oxnard, Christine M. Lovly, Hanna Tukachinsky, Vivek Subbiah
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (4): 836–848.
https://doi.org/10.1158/1078-0432.CCR-23-2693
Published: 16 February 2024
View article titled, Circulating Tumor DNA Enables Sensitive Detection of Actionable Gene Fusions and Rearrangements Across Cancer Types
Open the PDF for Circulating Tumor DNA Enables Sensitive Detection of Actionable Gene Fusions and Rearrangements Across Cancer Types in another window
Includes: Supplementary data
Journal Articles

Biology and Targetability of the Extended Spectrum of PIK3CA Mutations Detected in Breast Carcinoma

Hope S. Rugo, Kira Raskina, Alexa B. Schrock, Russell W. Madison, Ryon P. Graf, Ethan S. Sokol, Smruthy Sivakumar, Jessica K. Lee, Virginia Fisher, Geoffrey R. Oxnard, Hanna Tukachinsky
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (6): 1056–1067.
https://doi.org/10.1158/1078-0432.CCR-22-2115
Published: 14 March 2023
View article titled, Biology and Targetability of the Extended Spectrum of <em>PIK3CA</em> Mutations Detected in Breast Carcinoma
Open the PDF for Biology and Targetability of the Extended Spectrum of <em>PIK3CA</em> Mutations Detected in Breast Carcinoma in another window
Includes: Supplementary data
Journal Articles

The Pan-Tumor Landscape of Targetable Kinase Fusions in Circulating Tumor DNA

Jessica K. Lee, Mehlika Hazar-Rethinam, Brennan Decker, Ole Gjoerup, Russell W. Madison, Daniel S. Lieber, Jon H. Chung, Alexa B. Schrock, James Creeden, Jeffrey Venstrom, Brian Alexander, Geoffrey R. Oxnard
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (4): 728–737.
https://doi.org/10.1158/1078-0432.CCR-21-2136
Published: 15 February 2022
View article titled, The Pan-Tumor Landscape of Targetable Kinase Fusions in Circulating Tumor DNA
Open the PDF for The Pan-Tumor Landscape of Targetable Kinase Fusions in Circulating Tumor DNA in another window
Includes: Supplementary data