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Jessica K. Altman
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Journal Articles

Aurora Kinase A Inhibition Provides Clinical Benefit, Normalizes Megakaryocytes, and Reduces Bone Marrow Fibrosis in Patients with Myelofibrosis: A Phase I Trial

Naseema Gangat, Christian Marinaccio, Ronan Swords, Justin M. Watts, Sandeep Gurbuxani, Alfred Rademaker, Angela J. Fought, Olga Frankfurt, Jessica K. Altman, Qiang Jeremy Wen, Noushin Farnoud, Christopher A. Famulare, Akshar Patel, Roberto Tapia, Rangit R. Vallapureddy, Stephanie Barath, Amy Graf, Amy Handlogten, Darci Zblewski, Mrinal M. Patnaik, Aref Al-kali, Yvonne Trang Dinh, Kristen Englund Prahl, Shradha Patel, Juan Carlos Nobrega, Dalissa Tejera, Amber Thomassen, Juehua Gao, Peng Ji, Raajit K. Rampal, Francis J. Giles, Ayalew Tefferi, Brady Stein, John D. Crispino
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (16): 4898–4906.
https://doi.org/10.1158/1078-0432.CCR-19-1005
Published: 15 August 2019
View article titled, Aurora Kinase A Inhibition Provides Clinical Benefit, Normalizes Megakaryocytes, and Reduces Bone Marrow Fibrosis in Patients with Myelofibrosis: A Phase I Trial
Open the PDF for Aurora Kinase A Inhibition Provides Clinical Benefit, Normalizes Megakaryocytes, and Reduces Bone Marrow Fibrosis in Patients with Myelofibrosis: A Phase I Trial in another window
Includes: Supplementary data
Journal Articles

Autophagy Is a Survival Mechanism of Acute Myelogenous Leukemia Precursors during Dual mTORC2/mTORC1 Targeting

Jessica K. Altman, Amy Szilard, Dennis J. Goussetis, Antonella Sassano, Marco Colamonici, Elias Gounaris, Olga Frankfurt, Francis J. Giles, Elizabeth A. Eklund, Elspeth M. Beauchamp, Leonidas C. Platanias
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (9): 2400–2409.
https://doi.org/10.1158/1078-0432.CCR-13-3218
Published: 30 April 2014
View article titled, Autophagy Is a Survival Mechanism of Acute Myelogenous Leukemia Precursors during Dual mTORC2/mTORC1 Targeting
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Journal Articles

New Strategies in Acute Myeloid Leukemia: Redefining Prognostic Markers to Guide Therapy

Irum Khan, Jessica K. Altman, Jonathan D. Licht
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (19): 5163–5171.
https://doi.org/10.1158/1078-0432.CCR-12-0313
Published: 30 September 2012
View article titled, New Strategies in Acute Myeloid Leukemia: Redefining Prognostic Markers to Guide Therapy
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Journal Articles

Dual mTORC2/mTORC1 Targeting Results in Potent Suppressive Effects on Acute Myeloid Leukemia (AML) Progenitors

Jessica K. Altman, Antonella Sassano, Surinder Kaur, Heather Glaser, Barbara Kroczynska, Amanda J. Redig, Suzanne Russo, Sharon Barr, Leonidas C. Platanias
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (13): 4378–4388.
https://doi.org/10.1158/1078-0432.CCR-10-2285
Published: 05 July 2011
View article titled, Dual mTORC2/mTORC1 Targeting Results in Potent Suppressive Effects on Acute Myeloid Leukemia (AML) Progenitors
Open the PDF for Dual mTORC2/mTORC1 Targeting Results in Potent Suppressive Effects on Acute Myeloid Leukemia (AML) Progenitors in another window
Includes: Supplementary data