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Jennifer Y. Wo
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Journal Articles

Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Cancer Cells in Locally Advanced Pancreatic Cancer

Yves Boucher, Jessica M. Posada, Sonu Subudhi, Ashwin S. Kumar, Spencer R. Rosario, Liqun Gu, Heena Kumra, Mari Mino-Kenudson, Nilesh P. Talele, Dan G. Duda, Dai Fukumura, Jennifer Y. Wo, Jeffrey W. Clark, David P. Ryan, Carlos Fernandez-Del Castillo, Theodore S. Hong, Mikael J. Pittet, Rakesh K. Jain
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (8): 1605–1619.
https://doi.org/10.1158/1078-0432.CCR-22-1630
Published: 14 April 2023
View article titled, Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3<sup>+</sup> Cancer Cells in Locally Advanced Pancreatic Cancer
Open the PDF for Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3<sup>+</sup> Cancer Cells in Locally Advanced Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Results and Molecular Correlates from a Pilot Study of Neoadjuvant Induction FOLFIRINOX Followed by Chemoradiation and Surgery for Gastroesophageal Adenocarcinomas

Jennifer Y. Wo, Jeffrey W. Clark, Christine E. Eyler, Mari Mino-Kenudson, Samuel J. Klempner, Jill N. Allen, Florence K. Keane, Aparna R. Parikh, Eric Roeland, Lorraine C. Drapek, David P. Ryan, Ryan B. Corcoran, Emily Van Seventer, Isobel J. Fetter, Heather A. Shahzade, Melin J. Khandekar, Michael Lanuti, Christopher R. Morse, Rebecca S. Heist, Christine A. Ulysse, Benjamin Christopher, Christian Baglini, Beow Y. Yeap, John T. Mullen, Theodore S. Hong
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (23): 6343–6353.
https://doi.org/10.1158/1078-0432.CCR-21-0331
Published: 01 December 2021
View article titled, Results and Molecular Correlates from a Pilot Study of Neoadjuvant Induction FOLFIRINOX Followed by Chemoradiation and Surgery for Gastroesophageal Adenocarcinomas
Open the PDF for Results and Molecular Correlates from a Pilot Study of Neoadjuvant Induction FOLFIRINOX Followed by Chemoradiation and Surgery for Gastroesophageal Adenocarcinomas in another window
Includes: Supplementary data
Journal Articles

Minimal Residual Disease Detection using a Plasma-only Circulating Tumor DNA Assay in Patients with Colorectal Cancer

Aparna R. Parikh, Emily E. Van Seventer, Giulia Siravegna, Anna V. Hartwig, Ariel Jaimovich, Yupeng He, Katie Kanter, Madeleine G. Fish, Kathryn D. Fosbenner, Benchun Miao, Susannah Phillips, John H. Carmichael, Nihaarika Sharma, Joy Jarnagin, Islam Baiev, Yojan S. Shah, Isobel J. Fetter, Heather A. Shahzade, Jill N. Allen, Lawrence S. Blaszkowsky, Jeffrey W. Clark, Jon S. Dubois, Joseph W. Franses, Bruce J. Giantonio, Lipika Goyal, Samuel J. Klempner, Ryan D. Nipp, Eric J. Roeland, David P. Ryan, Colin D. Weekes, Jennifer Y. Wo, Theodore S. Hong, Liliana Bordeianou, Cristina R. Ferrone, Motaz Qadan, Hiroko Kunitake, David Berger, Rocco Ricciardi, James C. Cusack, Victoria M. Raymond, AmirAli Talasaz, Genevieve M. Boland, Ryan B. Corcoran
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (20): 5586–5594.
https://doi.org/10.1158/1078-0432.CCR-21-0410
Published: 15 October 2021
View article titled, Minimal Residual Disease Detection using a Plasma-only Circulating Tumor DNA Assay in Patients with Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Pan-cancer Transcriptomic Predictors of Perineural Invasion Improve Occult Histopathologic Detection

Jimmy A. Guo, Hannah I. Hoffman, Stuti G. Shroff, Peter Chen, Peter G. Hwang, Daniel Y. Kim, Daniel W. Kim, Stephanie W. Cheng, Daniel Zhao, Brandon A. Mahal, Mohammed Alshalalfa, Andrzej Niemierko, Jennifer Y. Wo, Jay S. Loeffler, Carlos Fernandez-del Castillo, Tyler Jacks, Andrew J. Aguirre, Theodore S. Hong, Mari Mino-Kenudson, William L. Hwang
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (10): 2807–2815.
https://doi.org/10.1158/1078-0432.CCR-20-4382
Published: 15 May 2021
View article titled, Pan-cancer Transcriptomic Predictors of Perineural Invasion Improve Occult Histopathologic Detection
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Includes: Supplementary data
Journal Articles

Serial ctDNA Monitoring to Predict Response to Systemic Therapy in Metastatic Gastrointestinal Cancers

Aparna R. Parikh, Amikasra Mojtahed, Jaime L. Schneider, Katie Kanter, Emily E. Van Seventer, Isobel J. Fetter, Ashraf Thabet, Madeleine G. Fish, Bezaye Teshome, Kathryn Fosbenner, Brandon Nadres, Heather A. Shahzade, Jill N. Allen, Lawrence S. Blaszkowsky, David P. Ryan, Bruce Giantonio, Lipika Goyal, Ryan D. Nipp, Eric Roeland, Colin D. Weekes, Jennifer Y. Wo, Andrew X. Zhu, Dora Dias-Santagata, A. John Iafrate, Jochen K. Lennerz, Theodore S. Hong, Giulia Siravegna, Nora Horick, Jeffrey W. Clark, Ryan B. Corcoran
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2020) 26 (8): 1877–1885.
https://doi.org/10.1158/1078-0432.CCR-19-3467
Published: 15 April 2020
View article titled, Serial ctDNA Monitoring to Predict Response to Systemic Therapy in Metastatic Gastrointestinal Cancers
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Includes: Supplementary data
Journal Articles

Integrative Molecular Characterization of Resistance to Neoadjuvant Chemoradiation in Rectal Cancer

Sophia C. Kamran, Jochen K. Lennerz, Claire A. Margolis, David Liu, Brendan Reardon, Stephanie A. Wankowicz, Emily E. Van Seventer, Adam Tracy, Jennifer Y. Wo, Scott L. Carter, Henning Willers, Ryan B. Corcoran, Theodore S. Hong, Eliezer M. Van Allen
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (18): 5561–5571.
https://doi.org/10.1158/1078-0432.CCR-19-0908
Published: 13 September 2019
View article titled, Integrative Molecular Characterization of Resistance to Neoadjuvant Chemoradiation in Rectal Cancer
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Includes: Supplementary data
Journal Articles

Circulating Oncometabolite 2-Hydroxyglutarate Is a Potential Surrogate Biomarker in Patients with Isocitrate Dehydrogenase-Mutant Intrahepatic Cholangiocarcinoma

Darrell R. Borger, Lipika Goyal, Thomas Yau, Ronnie T. Poon, Marek Ancukiewicz, Vikram Deshpande, David C. Christiani, Hannah M. Liebman, Hua Yang, Hyeryun Kim, Katharine Yen, Jason E. Faris, A. John Iafrate, Eunice L. Kwak, Jeffrey W. Clark, Jill N. Allen, Lawrence S. Blaszkowsky, Janet E. Murphy, Supriya K. Saha, Theodore S. Hong, Jennifer Y. Wo, Cristina R. Ferrone, Kenneth K. Tanabe, Nabeel Bardeesy, Kimberly S. Straley, Sam Agresta, David P. Schenkein, Leif W. Ellisen, David P. Ryan, Andrew X. Zhu
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (7): 1884–1890.
https://doi.org/10.1158/1078-0432.CCR-13-2649
Published: 31 March 2014
View article titled, Circulating Oncometabolite 2-Hydroxyglutarate Is a Potential Surrogate Biomarker in Patients with Isocitrate Dehydrogenase-Mutant Intrahepatic Cholangiocarcinoma
Open the PDF for Circulating Oncometabolite 2-Hydroxyglutarate Is a Potential Surrogate Biomarker in Patients with Isocitrate Dehydrogenase-Mutant Intrahepatic Cholangiocarcinoma in another window
Includes: Supplementary data