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Jelle Wesseling
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Journal Articles

Dynamic Changes in the NK-, Neutrophil-, and B-cell Immunophenotypes Relevant in High Metastatic Risk Post Neoadjuvant Chemotherapy–Resistant Early Breast Cancers

Patrycja Gazinska, Charlotte Milton, Jacopo Iacovacci, Joseph Ward, Richard Buus, Thanussuyah Alaguthurai, Rosalind Graham, Ayse Akarca, Esther Lips, Kalnisha Naidoo, Jelle Wesseling, Teresa Marafioti, Maggie Cheang, Cheryl Gillett, Yin Wu, Aadil Khan, Alan Melcher, Roberto Salgado, Mitch Dowsett, Andrew Tutt, Ioannis Roxanis, Syed Haider, Sheeba Irshad
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (20): 4494–4508.
https://doi.org/10.1158/1078-0432.CCR-22-0543
Published: 14 October 2022
View article titled, Dynamic Changes in the NK-, Neutrophil-, and B-cell Immunophenotypes Relevant in High Metastatic Risk Post Neoadjuvant Chemotherapy–Resistant Early Breast Cancers
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Includes: Supplementary data
Journal Articles

Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments

Lennart Kester, Danielle Seinstra, Annelot G.J. van Rossum, Claire Vennin, Marlous Hoogstraat, Daphne van der Velden, Mark Opdam, Erik van Werkhoven, Kerstin Hahn, Iris Nederlof, Ester H. Lips, Ingrid A.M. Mandjes, A. Elise van Leeuwen-Stok, Sander Canisius, Harm van Tinteren, Alex L.T. Imholz, Johanneke E.A. Portielje, Monique E.M.M. Bos, Sandra D. Bakker, Emiel J. Rutgers, Hugo M. Horlings, Jelle Wesseling, Emile E. Voest, Lodewyk F.A. Wessels, Marleen Kok, Hendrika M. Oosterkamp, Alexander van Oudenaarden, Sabine C. Linn, Jacco van Rheenen
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (5): 960–971.
https://doi.org/10.1158/1078-0432.CCR-21-1442
Published: 01 March 2022
View article titled, Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments
Open the PDF for Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments in another window
Includes: Supplementary data
Journal Articles

Abstract S02-02: The impact of resuming the breast cancer screening program in the Netherlands on breast cancer incidence and stage after its discontinuation due to the COVID-19 pandemic

Anouk H. Eijkelboom, Linda de Munck, Marc B.I. Lobbes, Jelle Wesseling, Carla H. van Gils, Pieter J. Westenend, Cristina Guerrero Paez, Ruud M. Pijnappel, Helena M. Verkooijen, Mireille J.M. Broeders, Sabine Siesling
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (6_Supplement): S02-02.
https://doi.org/10.1158/1557-3265.COVID-19-21-S02-02
Published: 15 March 2021
View article titled, Abstract S02-02: The impact of resuming the breast cancer screening program in the Netherlands on breast cancer incidence and stage after its discontinuation due to the COVID-19 pandemic
Journal Articles

Prognostic Value of Residual Disease after Neoadjuvant Therapy in HER2-Positive Breast Cancer Evaluated by Residual Cancer Burden, Neoadjuvant Response Index, and Neo-Bioscore

Tessa G. Steenbruggen, Maartje van Seijen, Liselore M. Janssen, Mette S. van Ramshorst, Erik van Werkhoven, Marie-Jeanne T.D.F. Vrancken Peeters, Jelle Wesseling, Esther H. Lips, Gabe S. Sonke
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (16): 4985–4992.
https://doi.org/10.1158/1078-0432.CCR-19-0560
Published: 15 August 2019
View article titled, Prognostic Value of Residual Disease after Neoadjuvant Therapy in HER2-Positive Breast Cancer Evaluated by Residual Cancer Burden, Neoadjuvant Response Index, and Neo-Bioscore
Open the PDF for Prognostic Value of Residual Disease after Neoadjuvant Therapy in HER2-Positive Breast Cancer Evaluated by Residual Cancer Burden, Neoadjuvant Response Index, and Neo-Bioscore in another window
Includes: Supplementary data
Journal Articles

EZH2 Is Overexpressed in BRCA1-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy

Julian Puppe, Mark Opdam, Philip C. Schouten, Katarzyna Jóźwiak, Esther Lips, Tesa Severson, Marieke van de Ven, Chiara Brambillasca, Peter Bouwman, Olaf van Tellingen, René Bernards, Jelle Wesseling, Christian Eichler, Fabinshy Thangarajah, Wolfram Malter, Gaurav Kumar Pandey, Luka Ozretić, Carlos Caldas, Maarten van Lohuizen, Michael Hauptmann, Kerstin Rhiem, Eric Hahnen, H. Christian Reinhardt, Reinhard Büttner, Peter Mallmann, Birgid Schömig-Markiefka, Rita Schmutzler, Sabine Linn, Jos Jonkers
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (14): 4351–4362.
https://doi.org/10.1158/1078-0432.CCR-18-4024
Published: 15 July 2019
View article titled, EZH2 Is Overexpressed in <em>BRCA1</em>-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy
Open the PDF for EZH2 Is Overexpressed in <em>BRCA1</em>-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy in another window
Includes: Supplementary data
Journal Articles

Clinicopathological Risk Factors for an Invasive Breast Cancer Recurrence after Ductal Carcinoma In Situ—A Nested Case–Control Study

Lindy L. Visser, Lotte E. Elshof, Michael Schaapveld, Koen van de Vijver, Emma J. Groen, Mathilde M. Almekinders, Carolien Bierman, Flora E. van Leeuwen, Emiel J. Rutgers, Marjanka K. Schmidt, Esther H. Lips, Jelle Wesseling
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (15): 3593–3601.
https://doi.org/10.1158/1078-0432.CCR-18-0201
Published: 31 July 2018
View article titled, Clinicopathological Risk Factors for an Invasive Breast Cancer Recurrence after Ductal Carcinoma <em>In Situ</em>—A Nested Case–Control Study
Open the PDF for Clinicopathological Risk Factors for an Invasive Breast Cancer Recurrence after Ductal Carcinoma <em>In Situ</em>—A Nested Case–Control Study in another window
Includes: Supplementary data
Journal Articles

BRCA1-Mutated Estrogen Receptor–Positive Breast Cancer Shows BRCAness, Suggesting Sensitivity to Drugs Targeting Homologous Recombination Deficiency

Esther H. Lips, Rashmie D. Debipersad, Caroline E. Scheerman, Lennart Mulder, Gabe S. Sonke, Lizet E. van der Kolk, Jelle Wesseling, Frans B.L. Hogervorst, Petra M. Nederlof
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (5): 1236–1241.
https://doi.org/10.1158/1078-0432.CCR-16-0198
Published: 28 February 2017
View article titled, <em>BRCA1</em>-Mutated Estrogen Receptor–Positive Breast Cancer Shows BRCAness, Suggesting Sensitivity to Drugs Targeting Homologous Recombination Deficiency
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Includes: Supplementary data
Journal Articles

Abstract PR3: Patient derived BRCA1-deficient triple-negative breast cancer xenografts develop resistance to DNA damaging agents via genetic and epigenetic mechanisms

Petra ter Brugge, Jelle Wesseling, Jos Jonkers, Eline van der Burg, Petra Kristel, Ute Boon, Cátia Moutinho, Manel Esteller, Frans Hogervorst, Heidrun Gevensleber, Nicholas Turner
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (10_Supplement): PR3.
https://doi.org/10.1158/1078-0432.MECHRES-PR3
Published: 04 March 2013
View article titled, Abstract PR3: Patient derived BRCA1-deficient triple-negative breast cancer xenografts develop resistance to DNA damaging agents via genetic and epigenetic mechanisms
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Journal Articles

TRAIL Induces Apoptosis in Human Colorectal Adenoma Cell Lines and Human Colorectal Adenomas

Mathilde Jalving, Steven de Jong, Jan J. Koornstra, Wytske Boersma-van Ek, Nynke Zwart, Jelle Wesseling, Elisabeth G.E. de Vries, Jan H. Kleibeuker
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (14): 4350–4356.
https://doi.org/10.1158/1078-0432.CCR-05-2487
Published: 20 July 2006
View article titled, TRAIL Induces Apoptosis in Human Colorectal Adenoma Cell Lines and Human Colorectal Adenomas
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