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Jeffrey W. Taub
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Journal Articles

Pharmacogenomic Score Effectively Personalizes Treatment of Acute Myeloid Leukemia

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Richard J. Marrero, Huiyun Wu, Xueyuan Cao, Phani Krishna Parcha, Abdelrahman H. Elsayed, Hiroto Inaba, Dennis John Kuo, Barbara A. Degar, Kenneth Heym, Jeffrey W. Taub, Norman Lacayo, Ching-Hon Pui, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley B. Pounds, Jatinder K. Lamba
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (19): 4388–4396.
https://doi.org/10.1158/1078-0432.CCR-24-0863
Published: 01 October 2024
View article titled, Pharmacogenomic Score Effectively Personalizes Treatment of Acute Myeloid Leukemia
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Includes: Supplementary data
Journal Articles

Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia

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Jun Ma, Shoujing Zhao, Xinan Qiao, Tristan Knight, Holly Edwards, Lisa Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Guan Wang, Lijing Zhao, Hai Lin, Yue Wang, Jeffrey W. Taub, Yubin Ge
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (22): 6815–6826.
https://doi.org/10.1158/1078-0432.CCR-19-0832
Published: 15 November 2019
View article titled, Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia
Open the PDF for Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia in another window
Includes: Supplementary data
Journal Articles

Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells

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Xiaojia Niu, Jianyun Zhao, Jun Ma, Chengzhi Xie, Holly Edwards, Guan Wang, J. Timothy Caldwell, Shengyan Xiang, Xiaohong Zhang, Roland Chu, Zhihong J. Wang, Hai Lin, Jeffrey W. Taub, Yubin Ge
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (17): 4440–4451.
https://doi.org/10.1158/1078-0432.CCR-15-3057
Published: 31 August 2016
View article titled, Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells
Open the PDF for Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells in another window
Includes: Supplementary data
Journal Articles

Mechanisms of Synergistic Antileukemic Interactions between Valproic Acid and Cytarabine in Pediatric Acute Myeloid Leukemia

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Chengzhi Xie, Holly Edwards, Xuelian Xu, Hui Zhou, Steven A. Buck, Mark L. Stout, Qun Yu, Jeffrey E. Rubnitz, Larry H. Matherly, Jeffrey W. Taub, Yubin Ge
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (22): 5499–5510.
https://doi.org/10.1158/1078-0432.CCR-10-1707
Published: 14 November 2010
View article titled, Mechanisms of Synergistic Antileukemic Interactions between Valproic Acid and Cytarabine in Pediatric Acute Myeloid Leukemia
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Journal Articles

Prognostic Role of the Reduced Folate Carrier, the Major Membrane Transporter for Methotrexate, in Childhood Acute Lymphoblastic Leukemia: A Report from the Children's Oncology Group

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Yubin Ge, Christina L. Haska, Katherine LaFiura, Meenakshi Devidas, Stephen B. Linda, Mingjun Liu, Ronald Thomas, Jeffrey W. Taub, Larry H. Matherly
Journal: Clinical Cancer Research
Clin Cancer Res (2007) 13 (2): 451–457.
https://doi.org/10.1158/1078-0432.CCR-06-2145
Published: 25 January 2007
View article titled, Prognostic Role of the Reduced Folate Carrier, the Major Membrane Transporter for Methotrexate, in Childhood Acute Lymphoblastic Leukemia: A Report from the Children's Oncology Group
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Journal Articles

Transcriptional Regulation of the Human Reduced Folate Carrier in Childhood Acute Lymphoblastic Leukemia Cells

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Mingjun Liu, Yubin Ge, Scott G. Payton, Amro Aboukameel, Stephen Buck, Robin M. Flatley, Christina Haska, Ramzi Mohammad, Jeffrey W. Taub, Larry H. Matherly
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (2): 608–616.
https://doi.org/10.1158/1078-0432.CCR-05-1954
Published: 20 January 2006
View article titled, Transcriptional Regulation of the Human Reduced Folate Carrier in Childhood Acute Lymphoblastic Leukemia Cells
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Journal Articles

Primary Acute Lymphoblastic Leukemia Cells Use a Novel Promoter and 5′Noncoding Exon for the Human Reduced Folate Carrier That Encodes a Modified Carrier Translated from an Upstream Translational Start

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Robin M. Flatley, Scott G. Payton, Jeffrey W. Taub, Larry H. Matherly
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (15): 5111–5122.
https://doi.org/10.1158/1078-0432.CCR-04-0116
Published: 05 August 2004
View article titled, Primary Acute Lymphoblastic Leukemia Cells Use a Novel Promoter and 5′Noncoding Exon for the Human Reduced Folate Carrier That Encodes a Modified Carrier Translated from an Upstream Translational Start
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Journal Articles

Single Nucleotide Polymorphisms in the Human Reduced Folate Carrier: Characterization of a High-Frequency G/A Variant at Position 80 and Transport Properties of the His27 and Arg27 Carriers

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Johnathan R. Whetstine, Andrew J. Gifford, Teah Witt, Xiang Y. Liu, Robin M. Flatley, Murray Norris, Michelle Haber, Jeffrey W. Taub, Y. Ravindranath, Larry H. Matherly
Journal: Clinical Cancer Research
Clin Cancer Res (2001) 7 (11): 3416–3422.
Published: 01 November 2001
View article titled, Single Nucleotide Polymorphisms in the Human Reduced Folate Carrier: Characterization of a High-Frequency G/A Variant at Position 80 and Transport Properties of the His27 and Arg27 Carriers
Open the PDF for Single Nucleotide Polymorphisms in the Human Reduced Folate Carrier: Characterization of a High-Frequency G/A Variant at Position 80 and Transport Properties of the His27 and Arg27 Carriers in another window