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Jeffrey S. Ross
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Journal Articles

Abstract P2-03-27: Prevalence of actionable genomic alterations (GA) and predictive value of tumor mutational burden (TMB) for immune checkpoint inhibitor (ICI) effectiveness in HR(+)HER2(-) metastatic breast cancer (MBC)

Free
Mariya Rozenblit, Julia C. F. Quintanilha, Jeffrey S. Ross, Mia Levy, Ryon P. Graf
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (12_Supplement): P2-03-27.
https://doi.org/10.1158/1557-3265.SABCS24-P2-03-27
Published: 13 June 2025
View articletitled, Abstract P2-03-27: Prevalence of actionable genomic alterations (GA) and predictive value of tumor mutational burden (TMB) for immune checkpoint inhibitor (ICI) effectiveness in HR(+)HER2(-) metastatic breast cancer (MBC)
Journal Articles

Abstract P3-05-30: Clinically Advanced Neuroendocrine Carcinoma of the Breast (CANEBC): A Genomic Landscape Study

Free
Melissa Taylor, Dean Pavlick, Ethan S. Sokol, Julia C. F. Quintanilla, Mia A Levy, Jeffrey S. Ross, Neal A Fischbach, Lajos Pusztai, Maryam Lustberg
Journal: Clinical Cancer Research
Clin Cancer Res (2025) 31 (12_Supplement): P3-05-30.
https://doi.org/10.1158/1557-3265.SABCS24-P3-05-30
Published: 13 June 2025
View articletitled, Abstract P3-05-30: Clinically Advanced Neuroendocrine Carcinoma of the Breast (CANEBC): A Genomic Landscape Study
Journal Articles

Comparative Genomic Analysis and Clinical Outcomes of BRAF-mutated Advanced Biliary Tract Cancers

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Tin-Yun Tang, Federico Nichetti, Ben Kaplan, Sara Lonardi, Filippo Pietrantonio, Lisa Salvatore, Caterina Vivaldi, Lorenza Rimassa, Filippo de Braud, Mario Domenico Rizzato, Dean Pavlick, Randy Chu, Anaemy Danner De Armas, Radwa Sharaf, Ethan Sokol, Jordi Rodon Ahnert, Jeffrey S. Ross, Milind Javle, Monica Niger
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (23): 4853–4862.
https://doi.org/10.1158/1078-0432.CCR-23-1926
Published: 01 December 2023
View articletitled, Comparative Genomic Analysis and Clinical Outcomes of BRAF-mutated Advanced Biliary Tract Cancers
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Includes: Supplementary data
Journal Articles

Neoadjuvant Pembrolizumab and Radical Cystectomy in Patients with Muscle-Invasive Urothelial Bladder Cancer: 3-Year Median Follow-Up Update of PURE-01 Trial

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Giuseppe Basile, Marco Bandini, Ewan A. Gibb, Jeffrey S. Ross, Daniele Raggi, Laura Marandino, Tiago Costa de Padua, Emanuele Crupi, Renzo Colombo, Maurizio Colecchia, Roberta Lucianò, Luigi Nocera, Marco Moschini, Alberto Briganti, Francesco Montorsi, Andrea Necchi
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (23): 5107–5114.
https://doi.org/10.1158/1078-0432.CCR-22-2158
Published: 01 December 2022
View articletitled, Neoadjuvant Pembrolizumab and Radical Cystectomy in Patients with Muscle-Invasive Urothelial Bladder Cancer: 3-Year Median Follow-Up Update of PURE-01 Trial
Open the PDF for Neoadjuvant Pembrolizumab and Radical Cystectomy in Patients with Muscle-Invasive Urothelial Bladder Cancer: 3-Year Median Follow-Up Update of PURE-01 Trial in another window
Includes: Supplementary data
Journal Articles

SPOP Mutations as a Predictive Biomarker for Androgen Receptor Axis–Targeted Therapy in De Novo Metastatic Castration-Sensitive Prostate Cancer

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Umang Swami, Ryon P. Graf, Roberto H. Nussenzveig, Virginia Fisher, Hanna Tukachinsky, Alexa B. Schrock, Gerald Li, Jeffrey S. Ross, Nicolas Sayegh, Nishita Tripathi, Vinay Mathew Thomas, Geoffrey R. Oxnard, Emmanuel S. Antonarakis, Neeraj Agarwal
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (22): 4917–4925.
https://doi.org/10.1158/1078-0432.CCR-22-2228
Published: 14 November 2022
View articletitled, SPOP Mutations as a Predictive Biomarker for Androgen Receptor Axis–Targeted Therapy in De Novo Metastatic Castration-Sensitive Prostate Cancer
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Includes: Supplementary data
Journal Articles

Genomic Analysis of Circulating Tumor DNA in 3,334 Patients with Advanced Prostate Cancer Identifies Targetable BRCA Alterations and AR Resistance Mechanisms

Free
Hanna Tukachinsky, Russell W. Madison, Jon H. Chung, Ole V. Gjoerup, Eric A. Severson, Lucas Dennis, Bernard J. Fendler, Samantha Morley, Lei Zhong, Ryon P. Graf, Jeffrey S. Ross, Brian M. Alexander, Wassim Abida, Simon Chowdhury, Charles J. Ryan, Karim Fizazi, Tony Golsorkhi, Simon P. Watkins, Andrew Simmons, Andrea Loehr, Jeffrey M. Venstrom, Geoffrey R. Oxnard
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2021) 27 (11): 3094–3105.
https://doi.org/10.1158/1078-0432.CCR-20-4805
Published: 01 June 2021
View articletitled, Genomic Analysis of Circulating Tumor DNA in 3,334 Patients with Advanced Prostate Cancer Identifies Targetable BRCA Alterations and AR Resistance Mechanisms
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Includes: Supplementary data
Journal Articles

Optimized EGFR Blockade Strategies in EGFR Addicted Gastroesophageal Adenocarcinomas

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Simona Corso, Filippo Pietrantonio, Maria Apicella, Cristina Migliore, Daniela Conticelli, Annalisa Petrelli, Laura D'Errico, Stefania Durando, Daniel Moya-Rull, Sara E. Bellomo, Stefano Ughetto, Maurizio Degiuli, Rossella Reddavid, Uberto Fumagalli, Stefano De Pascale, Giovanni Sgroi, Emanuele Rausa, Gian Luca Baiocchi, Sarah Molfino, Giovanni De Manzoni, Maria Bencivenga, Salvatore Siena, Andrea Sartore-Bianchi, Federica Morano, Salvatore Corallo, Michele Prisciandaro, Maria Di Bartolomeo, Annunziata Gloghini, Silvia Marsoni, Antonino Sottile, Anna Sapino, Caterina Marchiò, Asa Dahle-Smith, Zosia Miedzybrodzka, Jessica Lee, Siraj M. Ali, Jeffrey S. Ross, Brian M. Alexander, Vincent A. Miller, Russell Petty, Alexa B. Schrock, Silvia Giordano
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (11): 3126–3140.
https://doi.org/10.1158/1078-0432.CCR-20-0121
Published: 01 June 2021
View articletitled, Optimized EGFR Blockade Strategies in EGFR Addicted Gastroesophageal Adenocarcinomas
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Includes: Supplementary data
Journal Articles

Abstract PR07: Development of a biomarker-based nomogram to predict the pathologic response to neoadjuvant pembrolizumab in muscle-invasive urothelial bladder cancer (MIBC)

Free
Andrea Necchi, Marco Bandini, Daniele Raggi, Alberto Briganti, Elena Farè, Andrea Gallina, Renzo Colombo, Marco Bianchi, Maurizio Colecchia, Roberta Lucianò, Andrea Salonia, Filippo Pederzoli, Jeffrey S. Ross, Russell Madison, Francesco Montorsi, Siraj M. Ali, Jon H. Chung
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (15_Supplement): PR07.
https://doi.org/10.1158/1557-3265.BLADDER19-PR07
Published: 03 August 2020
View articletitled, Abstract PR07: Development of a biomarker-based nomogram to predict the pathologic response to neoadjuvant pembrolizumab in muscle-invasive urothelial bladder cancer (MIBC)
Journal Articles

Abstract GMM-025: ERBB FAMILY GENOMIC ALTERATIONS IN GYNECOLOGICAL MALIGNANCIES

Free
Laurie M Gay, Jo-Anne Vergilio, J Keith Killian, Shakti Ramkissoon, Eric Severson, Sugganth Daniel, Amanda Hemmerich, Jeffrey S Ross, Julia A Elvin
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (22_Supplement): GMM-025.
https://doi.org/10.1158/1557-3265.OVCASYMP18-GMM-025
Published: 15 November 2019
View articletitled, Abstract GMM-025: ERBB FAMILY GENOMIC ALTERATIONS IN GYNECOLOGICAL MALIGNANCIES
Journal Articles

On-target Resistance to the Mutant-Selective EGFR Inhibitor Osimertinib Can Develop in an Allele-Specific Manner Dependent on the Original EGFR-Activating Mutation

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Benjamin P. Brown, Yun-Kai Zhang, David Westover, Yingjun Yan, Huan Qiao, Vincent Huang, Zhenfang Du, Jarrod A. Smith, Jeffrey S. Ross, Vincent A. Miller, Siraj Ali, Lyudmila Bazhenova, Alexa B. Schrock, Jens Meiler, Christine M. Lovly
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2019) 25 (11): 3341–3351.
https://doi.org/10.1158/1078-0432.CCR-18-3829
Published: 03 June 2019
View articletitled, On-target Resistance to the Mutant-Selective EGFR Inhibitor Osimertinib Can Develop in an Allele-Specific Manner Dependent on the Original EGFR-Activating Mutation
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Includes: Multimedia, Supplementary data
Journal Articles

Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers

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Nikita Pozdeyev, Laurie M. Gay, Ethan S. Sokol, Ryan Hartmaier, Kelsi E. Deaver, Stephanie Davis, Jena D. French, Pierre Vanden Borre, Daniel V. LaBarbera, Aik-Choon Tan, Rebecca E. Schweppe, Lauren Fishbein, Jeffrey S. Ross, Bryan R. Haugen, Daniel W. Bowles
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (13): 3059–3068.
https://doi.org/10.1158/1078-0432.CCR-18-0373
Published: 01 July 2018
View articletitled, Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers
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Includes: Supplementary data
Journal Articles

Anaplastic Lymphoma Kinase Mutation (ALK F1174C) in Small Cell Carcinoma of the Prostate and Molecular Response to Alectinib

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Benedito A. Carneiro, Sahithi Pamarthy, Ami N. Shah, Vinay Sagar, Kenji Unno, HuiYing Han, Ximing J. Yang, Rubens B. Costa, Rebecca J. Nagy, Richard B. Lanman, Timothy M. Kuzel, Jeffrey S. Ross, Laurie Gay, Julia A. Elvin, Siraj M. Ali, Massimo Cristofanilli, Young K. Chae, Francis J. Giles, Sarki A. Abdulkadir
Journal: Clinical Cancer Research
Clin Cancer Res (2018) 24 (12): 2732–2739.
https://doi.org/10.1158/1078-0432.CCR-18-0332
Published: 14 June 2018
View articletitled, Anaplastic Lymphoma Kinase Mutation (ALK F1174C) in Small Cell Carcinoma of the Prostate and Molecular Response to Alectinib
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Includes: Supplementary data
Journal Articles

Hybrid Capture–Based Genomic Profiling of Circulating Tumor DNA from Patients with Advanced Cancers of the Gastrointestinal Tract or Anus

Free
Alexa B. Schrock, Dean Pavlick, Samuel J. Klempner, Jon H. Chung, Brady Forcier, Allison Welsh, Lauren Young, Bryan Leyland-Jones, Rodolfo Bordoni, Richard D. Carvajal, Joseph Chao, Razelle Kurzrock, Jason K. Sicklick, Jeffrey S. Ross, Philip J. Stephens, Craig Devoe, Fadi Braiteh, Siraj M. Ali, Vincent A. Miller
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2018) 24 (8): 1881–1890.
https://doi.org/10.1158/1078-0432.CCR-17-3103
Published: 12 April 2018
View articletitled, Hybrid Capture–Based Genomic Profiling of Circulating Tumor DNA from Patients with Advanced Cancers of the Gastrointestinal Tract or Anus
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Includes: Supplementary data
Journal Articles

Individualized Molecular Analyses Guide Efforts (IMAGE): A Prospective Study of Molecular Profiling of Tissue and Blood in Metastatic Triple-Negative Breast Cancer

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Heather A. Parsons, Julia A. Beaver, Ashley Cimino-Mathews, Siraj M. Ali, Jennifer Axilbund, David Chu, Roisin M. Connolly, Rory L. Cochran, Sarah Croessmann, Travis A. Clark, Christopher D. Gocke, Stacie C. Jeter, Mark R. Kennedy, Josh Lauring, Justin Lee, Doron Lipson, Vincent A. Miller, Geoff A. Otto, Gary L. Rosner, Jeffrey S. Ross, Shannon Slater, Philip J. Stephens, Dustin A. VanDenBerg, Antonio C. Wolff, Lauren E. Young, Daniel J. Zabransky, Zhe Zhang, Jane Zorzi, Vered Stearns, Ben H. Park
Journal: Clinical Cancer Research
Clin Cancer Res (2017) 23 (2): 379–386.
https://doi.org/10.1158/1078-0432.CCR-16-1543
Published: 15 January 2017
View articletitled, Individualized Molecular Analyses Guide Efforts (IMAGE): A Prospective Study of Molecular Profiling of Tissue and Blood in Metastatic Triple-Negative Breast Cancer
Open the PDF for Individualized Molecular Analyses Guide Efforts (IMAGE): A Prospective Study of Molecular Profiling of Tissue and Blood in Metastatic Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Profiling of 149 Salivary Duct Carcinomas, Carcinoma Ex Pleomorphic Adenomas, and Adenocarcinomas, Not Otherwise Specified Reveals Actionable Genomic Alterations

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Kai Wang, Jeffery S. Russell, Jessica D. McDermott, Julia A. Elvin, Depinder Khaira, Adrienne Johnson, Timothy A. Jennings, Siraj M. Ali, Molly Murray, Carrie Marshall, Dwight S. Oldham, Donna Washburn, Stuart J. Wong, Juliann Chmielecki, Roman Yelensky, Doron Lipson, Vincent A. Miller, Philip J. Stephens, Hilary S. Serracino, Jeffrey S. Ross, Daniel W. Bowles
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (24): 6061–6068.
https://doi.org/10.1158/1078-0432.CCR-15-2568
Published: 15 December 2016
View articletitled, Profiling of 149 Salivary Duct Carcinomas, Carcinoma Ex Pleomorphic Adenomas, and Adenocarcinomas, Not Otherwise Specified Reveals Actionable Genomic Alterations
Open the PDF for Profiling of 149 Salivary Duct Carcinomas, Carcinoma Ex Pleomorphic Adenomas, and Adenocarcinomas, Not Otherwise Specified Reveals Actionable Genomic Alterations in another window
Includes: Supplementary data
Journal Articles

Oncogenic ALK Fusion in Rare and Aggressive Subtype of Colorectal Adenocarcinoma as a Potential Therapeutic Target

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Evgeny Yakirevich, Murray B. Resnick, Shamlal Mangray, Michael Wheeler, Cynthia L. Jackson, Kara A. Lombardo, Jeeyun Lee, Kyoung-Mee Kim, Anthony J. Gill, Kai Wang, Kyle Gowen, James Sun, Vincent A. Miller, Philip J. Stephens, Siraj M. Ali, Jeffrey S. Ross, Howard Safran
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (15): 3831–3840.
https://doi.org/10.1158/1078-0432.CCR-15-3000
Published: 31 July 2016
View articletitled, Oncogenic ALK Fusion in Rare and Aggressive Subtype of Colorectal Adenocarcinoma as a Potential Therapeutic Target
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Includes: Supplementary data
Journal Articles

Comprehensive Genomic Profiling Identifies Frequent Drug-Sensitive EGFR Exon 19 Deletions in NSCLC not Identified by Prior Molecular Testing

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Alexa B. Schrock, Garrett M. Frampton, Dana Herndon, Joel R. Greenbowe, Kai Wang, Doron Lipson, Roman Yelensky, Zachary R. Chalmers, Juliann Chmielecki, Julia A. Elvin, Mira Wollner, Addie Dvir, Lior Soussan -Gutman, Rodolfo Bordoni, Nir Peled, Fadi Braiteh, Luis Raez, Rachel Erlich, Sai-Hong Ignatius Ou, Mohamed Mohamed, Jeffrey S. Ross, Philip J. Stephens, Siraj M. Ali, Vincent A. Miller
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2016) 22 (13): 3281–3285.
https://doi.org/10.1158/1078-0432.CCR-15-1668
Published: 30 June 2016
View articletitled, Comprehensive Genomic Profiling Identifies Frequent Drug-Sensitive EGFR Exon 19 Deletions in NSCLC not Identified by Prior Molecular Testing
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Journal Articles

Abstract B06: Distinct genomic profiles and targetable alterations revealed by FoundationOne® Heme in hematolymphoid malignancies in adolescents and young adults.

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Kai Wang, Deborah Morosini, Roman Yelensky, Doron Lipson, Juliann Chmielecki, Siraj M. Ali, Jeffrey S. Ross, Phil Stephens, Vincent A. Miller
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (17_Supplement): B06.
https://doi.org/10.1158/1557-3265.HEMMAL14-B06
Published: 19 August 2015
View articletitled, Abstract B06: Distinct genomic profiles and targetable alterations revealed by FoundationOne® Heme in hematolymphoid malignancies in adolescents and young adults.
Journal Articles

Broad, Hybrid Capture–Based Next-Generation Sequencing Identifies Actionable Genomic Alterations in Lung Adenocarcinomas Otherwise Negative for Such Alterations by Other Genomic Testing Approaches

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Alexander Drilon, Lu Wang, Maria E. Arcila, Sohail Balasubramanian, Joel R. Greenbowe, Jeffrey S. Ross, Phil Stephens, Doron Lipson, Vincent A. Miller, Mark G. Kris, Marc Ladanyi, Naiyer A. Rizvi
Journal: Clinical Cancer Research
Series: Author Choice
Clin Cancer Res (2015) 21 (16): 3631–3639.
https://doi.org/10.1158/1078-0432.CCR-14-2683
Published: 13 August 2015
View articletitled, Broad, Hybrid Capture–Based Next-Generation Sequencing Identifies Actionable Genomic Alterations in Lung Adenocarcinomas Otherwise Negative for Such Alterations by Other Genomic Testing Approaches
Open the PDF for Broad, Hybrid Capture–Based Next-Generation Sequencing Identifies Actionable Genomic Alterations in Lung Adenocarcinomas Otherwise Negative for Such Alterations by Other Genomic Testing Approaches in another window
Includes: Supplementary data
Journal Articles

Melanoma BRAF Fusions—Response

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Katherine E. Hutchinson, Jeffrey S. Ross, Philip J. Stephens, Vincent A. Miller, Jeffrey A. Sosman, William Pao
Journal: Clinical Cancer Research
Clin Cancer Res (2014) 20 (24): 6632.
https://doi.org/10.1158/1078-0432.CCR-14-1152
Published: 14 December 2014
View articletitled, Melanoma BRAF Fusions—Response
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