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Journal Articles

Induction Chemotherapy with or without Erlotinib in Patients with Head and Neck Squamous Cell Carcinoma Amenable for Surgical Resection

Clin Cancer Res OF1–OF11.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-3239

Published: 12 May 2022

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Includes: Supplementary data

Journal Articles

Correction: Pilot Phase II Trial of Neoadjuvant Immunotherapy in Locoregionally Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck

Clin Cancer Res (2022) 28 (8): 1735.

DOI: https://doi.org/10.1158/1078-0432.CCR-22-0468

Published: 14 April 2022

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Includes: Supplementary data

Journal Articles

Pilot Phase II Trial of Neoadjuvant Immunotherapy in Locoregionally Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck

Clin Cancer Res (2021) 27 (16): 4557–4565.

DOI: https://doi.org/10.1158/1078-0432.CCR-21-0585

Published: 29 June 2021

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Includes: Supplementary data

Journal Articles

Impact of Neoadjuvant Durvalumab with or without Tremelimumab on CD8⁺ Tumor Lymphocyte Density, Safety, and Efficacy in Patients with Oropharynx Cancer: CIAO Trial Results

Renata Ferrarotto, Diana Bell, Maria L. Rubin, Katherine A. Hutcheson, Jason M. Johnson, Ryan P. Goepfert, Jack Phan, Yasir Y. Elamin, Danice K. Torman, Carla L. Warneke, Amy C. Hessel, Adam S. Garden, Jeffrey N. Myers, Faye M. Johnson, J. Jack Lee, Andrew G. Sikora, Maura L. Gillison, Bonnie S. Glisson, Neil D. Gross

Clin Cancer Res (2020) 26 (13): 3211–3219.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-3977

Published: 01 July 2020

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Includes: Supplementary data

Journal Articles

Abstract PR08: Inhibition of ATR as a therapeutic strategy to overcome cisplatin resistance in HNSCC

Antje Lindemann, Hideaki Takahashi, Ameeta A. Patel, Walter N. Hittelman, Abdullah A. Osman, Jeffrey N. Myers

Clin Cancer Res (2020) 26 (12_Supplement_2): PR08.

DOI: https://doi.org/10.1158/1557-3265.AACRAHNS19-PR08

Published: 15 June 2020

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Journal Articles

Abstract B18: Loss of caspase-8 renders head and neck squamous cell carcinomas susceptible to necroptosis

Burak Uzunparmak, Jeffrey N. Myers, Curtis R. Pickering

Clin Cancer Res (2020) 26 (12_Supplement_2): B18.

DOI: https://doi.org/10.1158/1557-3265.AACRAHNS19-B18

Published: 15 June 2020

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Journal Articles

Abstract B08: Overcoming cisplatin resistance in sinonasal undifferentiated carcinoma by inhibiting the TGFβ signaling pathway in vivo

Yoko Takahashi, Hideaki Takahashi, Moran Amit, Frederico O. Gleber-Netto, Diana Bell, Tong-Xin Xie, Dianna Roberts, Ahmed S. Abdelmeguid, Curtis Pickering, Jeffrey N. Myers, Ehab Y. Hanna

Clin Cancer Res (2020) 26 (12_Supplement_2): B08.

DOI: https://doi.org/10.1158/1557-3265.AACRAHNS19-B08

Published: 15 June 2020

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Abstract B14: Variations in the proteasome activity are associated with human papilloma virus (HPV) gene expression and patient survival in HPV+ oropharyngeal tumors

Frederico O. Gleber-Netto, Meng Gao, Li Shen, Jing Wang, Jeffrey N. Myers, Faye M. Johnson, Curtis R. Pickering

Clin Cancer Res (2020) 26 (12_Supplement_2): B14.

DOI: https://doi.org/10.1158/1557-3265.AACRAHNS19-B14

Published: 15 June 2020

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Journal Articles

COTI-2, A Novel Thiosemicarbazone Derivative, Exhibits Antitumor Activity in HNSCC through p53-dependent and -independent Mechanisms

Clin Cancer Res (2019) 25 (18): 5650–5662.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-0096

Published: 13 September 2019

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Includes: Multimedia, Supplementary data

Journal Articles

Editor's Note: Epidermal Growth Factor Receptor (EGFR) Is Overexpressed in Anaplastic Thyroid Cancer, and the EGFR Inhibitor Gefitinib Inhibits the Growth of Anaplastic Thyroid Cancer

Bradley A. Schiff, Andrea B. McMurphy, Samar A. Jasser, Maher N. Younes, Dao Doan, Orhan G. Yigitbasi, Seungwon Kim, Ge Zhou, Mahitosh Mandal, Benjamin N. Bekele, F. Christopher Holsinger, Steven I. Sherman, Sai-Ching Yeung, Adel K. El-Naggar, Jeffrey N. Myers

Clin Cancer Res (2019) 25 (15): 4862.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-2052

Published: 01 August 2019

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Journal Articles

Editor's Note: Identification of Insulin-Like Growth Factor Binding Protein-3 as a Farnesyl Transferase Inhibitor SCH66336-Induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma

Seung-Hyun Oh, Woo-Young Kim, Jai-Hyun Kim, Maher N. Younes, Adel K. El-Naggar, Jeffrey N. Myers, Merril Kies, Pinchas Cohen, Fadlo Khuri, Waun K. Hong, Ho-Young Lee

Clin Cancer Res (2019) 25 (15): 4861.

DOI: https://doi.org/10.1158/1078-0432.CCR-19-2054

Published: 01 August 2019

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Journal Articles

High-Risk TP53 Mutations Are Associated with Extranodal Extension in Oral Cavity Squamous Cell Carcinoma

Vlad C. Sandulache, Chieko Michikawa, Pranav Kataria, Frederico O. Gleber-Netto, Diana Bell, Sanchit Trivedi, Xiayu Rao, Jing Wang, Mei Zhao, Samar Jasser, Jeffrey N. Myers, Curtis R. Pickering

Clin Cancer Res (2018) 24 (7): 1727–1733.

DOI: https://doi.org/10.1158/1078-0432.CCR-17-0721

Published: 02 April 2018

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Includes: Supplementary data

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Abstract IA12: An in vivo high throughput shRNA screening platform for identifying ways to target genomic alterations

Tongxin Xie, Ramya L. Parimi, Manish F. Kumar, Liang P. Yang, Jiping Wang, Sahil Seth, Carugo Alessandro, Christopher A. Bristow, Frederick Scott Robinson, Michael D. Peoples, Heath Skinner, Jeffrey N. Myers, Curtis R. Pickering, Mitchell J. Frederick

Clin Cancer Res (2017) 23 (23_Supplement): IA12.

DOI: https://doi.org/10.1158/1557-3265.AACRAHNS17-IA12

Published: 30 November 2017

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Journal Articles

Abstract 69: Proton versus photon irradiation induced cell death in head and neck cancer cells with different human papillomavirus status

Li Wang, Shichao Han, Jinming Zhu, Xiaochun Wang, Yuting Li, Zeming Wang, Eric Lin, Xiaofang Wang, David P. Molkentine, Pierre Blanchard, Yining Yang, Ruiping Zhang, Narayan Sahoo, Michael Gillin, Xiaorong Ronald Zhu, Xiaodong Zhang, Jeffrey N. Myers, Steven J. Frank

Clin Cancer Res (2017) 23 (23_Supplement): 69.

DOI: https://doi.org/10.1158/1557-3265.AACRAHNS17-69

Published: 30 November 2017

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Journal Articles

Abstract 42: Identification of gene expression patterns distinguishing responders and non-responders to induction chemotherapy in sinonasal undifferentiated carcinoma

Yoko Takahashi, Diana Bell, Frederico O. Gleber-Netto, Tong-Xin Xie, Dianna Roberts, Curtis Pickering, Jeffrey N. Myers, Ehab Y. Hanna

Clin Cancer Res (2017) 23 (23_Supplement): 42.

DOI: https://doi.org/10.1158/1557-3265.AACRAHNS17-42

Published: 30 November 2017

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Journal Articles

Abstract IA10: Integrated omics analyses identify prognostic biomarkers of oral cavity squamous cell carcinoma in Taiwan

Kai-Ping Chang, Ting-Wen Chen, Curtis R. Pickering, Jeffrey N. Myers, Yu-Sun Chang

Clin Cancer Res (2017) 23 (23_Supplement): IA10.

DOI: https://doi.org/10.1158/1557-3265.AACRAHNS17-IA10

Published: 30 November 2017

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Journal Articles

Abstract 04: Caspase-8 is a novel candidate driver gene in head and neck squamous cell carcinoma

Burak Uzunparmak, Antje Lindemann, Mitchell J. Frederick, Jeffrey N. Myers, Curtis R. Pickering

Clin Cancer Res (2017) 23 (23_Supplement): 04.

DOI: https://doi.org/10.1158/1557-3265.AACRAHNS17-04

Published: 30 November 2017

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Journal Articles

Abstract 73: Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cell by targeting forkhead transcription factors FOXO3a and FOXM1

Noriaki Tanaka, Mei Zhao, Jiexin Zhang, Jing Wang, Ge Zhou, Jeffrey N. Myers

Clin Cancer Res (2017) 23 (23_Supplement): 73.

DOI: https://doi.org/10.1158/1557-3265.AACRAHNS17-73

Published: 30 November 2017

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Journal Articles

Abstract 44: Synergistic antitumor activity of olaparib combined with AZD1775 in head and neck squamous cell carcinoma

Hideaki Takahashi, Antje Lindemann, Ameeta A. Patel, Weiwei Liu, Noriaki Tanaka, Lin Tang, Mei Zhao, Walter N. Hittelman, Jeffrey N. Myers, Abdullah A. Osman

Clin Cancer Res (2017) 23 (23_Supplement): 44.

DOI: https://doi.org/10.1158/1557-3265.AACRAHNS17-44

Published: 30 November 2017

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Journal Articles

Replication Stress Leading to Apoptosis within the S-phase Contributes to Synergism between Vorinostat and AZD1775 in HNSCC Harboring High-Risk TP53 Mutation

Clin Cancer Res (2017) 23 (21): 6541–6554.

DOI: https://doi.org/10.1158/1078-0432.CCR-17-0947

Published: 31 October 2017

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Includes: Multimedia, Supplementary data

2 3

NARROW

Induction Chemotherapy with or without Erlotinib in Patients with Head and Neck Squamous Cell Carcinoma Amenable for Surgical Resection

Correction: Pilot Phase II Trial of Neoadjuvant Immunotherapy in Locoregionally Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck

Pilot Phase II Trial of Neoadjuvant Immunotherapy in Locoregionally Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck

Impact of Neoadjuvant Durvalumab with or without Tremelimumab on CD8⁺ Tumor Lymphocyte Density, Safety, and Efficacy in Patients with Oropharynx Cancer: CIAO Trial Results

Abstract PR08: Inhibition of ATR as a therapeutic strategy to overcome cisplatin resistance in HNSCC

Abstract B18: Loss of caspase-8 renders head and neck squamous cell carcinomas susceptible to necroptosis

Abstract B08: Overcoming cisplatin resistance in sinonasal undifferentiated carcinoma by inhibiting the TGFβ signaling pathway in vivo

Abstract B14: Variations in the proteasome activity are associated with human papilloma virus (HPV) gene expression and patient survival in HPV+ oropharyngeal tumors

COTI-2, A Novel Thiosemicarbazone Derivative, Exhibits Antitumor Activity in HNSCC through p53-dependent and -independent Mechanisms

Editor's Note: Epidermal Growth Factor Receptor (EGFR) Is Overexpressed in Anaplastic Thyroid Cancer, and the EGFR Inhibitor Gefitinib Inhibits the Growth of Anaplastic Thyroid Cancer

Editor's Note: Identification of Insulin-Like Growth Factor Binding Protein-3 as a Farnesyl Transferase Inhibitor SCH66336-Induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma

High-Risk TP53 Mutations Are Associated with Extranodal Extension in Oral Cavity Squamous Cell Carcinoma

Abstract IA12: An in vivo high throughput shRNA screening platform for identifying ways to target genomic alterations

Abstract 69: Proton versus photon irradiation induced cell death in head and neck cancer cells with different human papillomavirus status

Abstract 42: Identification of gene expression patterns distinguishing responders and non-responders to induction chemotherapy in sinonasal undifferentiated carcinoma

Abstract IA10: Integrated omics analyses identify prognostic biomarkers of oral cavity squamous cell carcinoma in Taiwan

Abstract 04: Caspase-8 is a novel candidate driver gene in head and neck squamous cell carcinoma

Abstract 73: Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cell by targeting forkhead transcription factors FOXO3a and FOXM1

Abstract 44: Synergistic antitumor activity of olaparib combined with AZD1775 in head and neck squamous cell carcinoma

Replication Stress Leading to Apoptosis within the S-phase Contributes to Synergism between Vorinostat and AZD1775 in HNSCC Harboring High-Risk TP53 Mutation

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