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Jeffrey A. Meyerhardt
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Journal Articles

Plasma Protein Biomarkers in Advanced or Metastatic Colorectal Cancer Patients Receiving Chemotherapy With Bevacizumab or Cetuximab: Results from CALGB 80405 (Alliance)

Andrew B. Nixon, Alexander B. Sibley, Yingmiao Liu, Ace J. Hatch, Chen Jiang, Flora Mulkey, Mark D. Starr, John C. Brady, Donna Niedzwiecki, Alan P. Venook, Luis Baez-Diaz, Heinz-Josef Lenz, Bert H. O'Neil, Federico Innocenti, Jeffrey A. Meyerhardt, Eileen M. O'Reilly, Kouros Owzar, Herbert I. Hurwitz
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (13): 2779–2788.
DOI: https://doi.org/10.1158/1078-0432.CCR-21-2389
Published: 01 July 2022
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Association of Fusobacterium nucleatum with Specific T-cell Subsets in the Colorectal Carcinoma Microenvironment

Jennifer Borowsky, Koichiro Haruki, Mai Chan Lau, Andressa Dias Costa, Juha P. Väyrynen, Tomotaka Ugai, Kota Arima, Annacarolina da Silva, Kristen D. Felt, Melissa Zhao, Carino Gurjao, Tyler S. Twombly, Kenji Fujiyoshi, Sara A. Väyrynen, Tsuyoshi Hamada, Kosuke Mima, Susan Bullman, Tabitha A. Harrison, Amanda I. Phipps, Ulrike Peters, Kimmie Ng, Jeffrey A. Meyerhardt, Mingyang Song, Edward L. Giovannucci, Kana Wu, Xuehong Zhang, Gordon J. Freeman, Curtis Huttenhower, Wendy S. Garrett, Andrew T. Chan, Barbara A. Leggett, Vicki L.J. Whitehall, Neal Walker, Ian Brown, Mark Bettington, Reiko Nishihara, Charles S. Fuchs, Jochen K. Lennerz, Marios Giannakis, Jonathan A. Nowak, Shuji Ogino
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (10): 2816–2826.
DOI: https://doi.org/10.1158/1078-0432.CCR-20-4009
Published: 15 May 2021
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Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions

Harshabad Singh, Yvonne Y. Li, Liam F. Spurr, Atul B. Shinagare, Ritika Abhyankar, Emma Reilly, Lauren K. Brais, Anwesha Nag, Matthew D. Ducar, Aaron R. Thorner, Geoffrey I. Shapiro, Rachel B. Keller, Cheta Siletti, Jeffrey W. Clark, Anna F. Farago, Jessica J. Lin, George D. Demetri, Rahul Gujrathi, Matthew H. Kulke, Laura E. MacConaill, Azra H. Ligon, Ewa Sicinska, Matthew L. Meyerson, Jeffrey A. Meyerhardt, Andrew D. Cherniack, Brian M. Wolpin, Kimmie Ng, Marios Giannakis, Jason L. Hornick, James M. Cleary
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (6): 1695–1705.
DOI: https://doi.org/10.1158/1078-0432.CCR-20-4073
Published: 15 March 2021
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Prognostic Significance of Immune Cell Populations Identified by Machine Learning in Colorectal Cancer Using Routine Hematoxylin and Eosin–Stained Sections

Juha P. Väyrynen, Mai Chan Lau, Koichiro Haruki, Sara A. Väyrynen, Andressa Dias Costa, Jennifer Borowsky, Melissa Zhao, Kenji Fujiyoshi, Kota Arima, Tyler S. Twombly, Junko Kishikawa, Simeng Gu, Saina Aminmozaffari, Shanshan Shi, Yoshifumi Baba, Naohiko Akimoto, Tomotaka Ugai, Annacarolina Da Silva, Mingyang Song, Kana Wu, Andrew T. Chan, Reiko Nishihara, Charles S. Fuchs, Jeffrey A. Meyerhardt, Marios Giannakis, Shuji Ogino, Jonathan A. Nowak
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (16): 4326–4338.
DOI: https://doi.org/10.1158/1078-0432.CCR-20-0071
Published: 14 August 2020
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Plasma 25-Hydroxyvitamin D Levels and Survival in Patients with Advanced or Metastatic Colorectal Cancer: Findings from CALGB/SWOG 80405 (Alliance)

Chen Yuan, Kaori Sato, Bruce W. Hollis, Sui Zhang, Donna Niedzwiecki, Fang-Shu Ou, I-Wen Chang, Bert H. O'Neil, Federico Innocenti, Heinz-Josef Lenz, Charles D. Blanke, Richard M. Goldberg, Alan P. Venook, Robert J. Mayer, Charles S. Fuchs, Jeffrey A. Meyerhardt, Kimmie Ng
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (24): 7497–7505.
DOI: https://doi.org/10.1158/1078-0432.CCR-19-0877
Published: 13 December 2019
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Calcium Intake and Survival after Colorectal Cancer Diagnosis

Wanshui Yang, Yanan Ma, Stephanie Smith-Warner, Mingyang Song, Kana Wu, Molin Wang, Andrew T. Chan, Shuji Ogino, Charles S. Fuchs, Vitaliy Poylin, Kimmie Ng, Jeffrey A. Meyerhardt, Edward L. Giovannucci, Xuehong Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (6): 1980–1988.
DOI: https://doi.org/10.1158/1078-0432.CCR-18-2965
Published: 15 March 2019
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MicroRNA MIR21 (miR-21) and PTGS2 Expression in Colorectal Cancer and Patient Survival

Kosuke Mima, Reiko Nishihara, Juhong Yang, Ruoxu Dou, Yohei Masugi, Yan Shi, Annacarolina da Silva, Yin Cao, Mingyang Song, Jonathan Nowak, Mancang Gu, Wanwan Li, Teppei Morikawa, Xuehong Zhang, Kana Wu, Hideo Baba, Edward L. Giovannucci, Jeffrey A. Meyerhardt, Andrew T. Chan, Charles S. Fuchs, Zhi Rong Qian, Shuji Ogino
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (15): 3841–3848.
DOI: https://doi.org/10.1158/1078-0432.CCR-15-2173
Published: 31 July 2016
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Prognostic Utility of Molecular Factors by Age at Diagnosis of Colorectal Cancer

Nadine J. McCleary, Kaori Sato, Reiko Nishihara, Kentaro Inamura, Teppei Morikawa, Xuehong Zhang, Kana Wu, Mai Yamauchi, Sun A. Kim, Yasutaka Sukawa, Kosuke Mima, Zhi Rong Qian, Charles S. Fuchs, Shuji Ogino, Jeffrey A. Meyerhardt
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (6): 1489–1498.
DOI: https://doi.org/10.1158/1078-0432.CCR-15-0946
Published: 14 March 2016
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Efficacy, Safety, Pharmacokinetics, and Biomarkers of Cediranib Monotherapy in Advanced Hepatocellular Carcinoma: A Phase II Study

Andrew X. Zhu, Marek Ancukiewicz, Jeffrey G. Supko, Dushyant V. Sahani, Lawrence S. Blaszkowsky, Jeffrey A. Meyerhardt, Thomas A. Abrams, Nadine Jackson McCleary, Pankaj Bhargava, Alona Muzikansky, Susan Sheehan, Eileen Regan, Eamala Vasudev, Michelle Knowles, Charles S. Fuchs, David P. Ryan, Rakesh K. Jain, Dan G. Duda
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (6): 1557–1566.
DOI: https://doi.org/10.1158/1078-0432.CCR-12-3041
Published: 14 March 2013
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Specific Mutations in KRAS Codons 12 and 13, and Patient Prognosis in 1075 BRAF Wild-Type Colorectal Cancers

Yu Imamura, Teppei Morikawa, Xiaoyun Liao, Paul Lochhead, Aya Kuchiba, Mai Yamauchi, Zhi Rong Qian, Reiko Nishihara, Jeffrey A. Meyerhardt, Kevin M. Haigis, Charles S. Fuchs, Shuji Ogino
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (17): 4753–4763.
DOI: https://doi.org/10.1158/1078-0432.CCR-11-3210
Published: 30 August 2012
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Prognostic Role of PIK3CA Mutation in Colorectal Cancer: Cohort Study and Literature Review

Xiaoyun Liao, Teppei Morikawa, Paul Lochhead, Yu Imamura, Aya Kuchiba, Mai Yamauchi, Katsuhiko Nosho, Zhi Rong Qian, Reiko Nishihara, Jeffrey A. Meyerhardt, Charles S. Fuchs, Shuji Ogino
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (8): 2257–2268.
DOI: https://doi.org/10.1158/1078-0432.CCR-11-2410
Published: 16 April 2012
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Predictive and Prognostic Roles of BRAF Mutation in Stage III Colon Cancer: Results from Intergroup Trial CALGB 89803

Shuji Ogino, Kaori Shima, Jeffrey A. Meyerhardt, Nadine J. McCleary, Kimmie Ng, Donna Hollis, Leonard B. Saltz, Robert J. Mayer, Paul Schaefer, Renaud Whittom, Alexander Hantel, Al B. Benson, III, Donna Spiegelman, Richard M. Goldberg, Monica M. Bertagnolli, Charles S. Fuchs
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3): 890–900.
DOI: https://doi.org/10.1158/1078-0432.CCR-11-2246
Published: 31 January 2012
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KRAS Mutation in Stage III Colon Cancer and Clinical Outcome Following Intergroup Trial CALGB 89803

Shuji Ogino, Jeffrey A. Meyerhardt, Natsumi Irahara, Donna Niedzwiecki, Donna Hollis, Leonard B. Saltz, Robert J. Mayer, Paul Schaefer, Renaud Whittom, Alexander Hantel, Al B. Benson, III, Richard M. Goldberg, Monica M. Bertagnolli, Charles S. Fuchs, for the Cancer and Leukemia Group B, North Central Cancer Treatment Group, Canadian Cancer Society Research Institute, Southwest Oncology Group
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (23): 7322–7329.
DOI: https://doi.org/10.1158/1078-0432.CCR-09-1570
Published: 30 November 2009
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Getting Knit-PI3Ky: PIK3CA Mutation Status to Direct Multimodality Therapy?

Andrea P. Myers, Jeffrey A. Meyerhardt, Lewis C. Cantley
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (22): 6748–6750.
DOI: https://doi.org/10.1158/1078-0432.CCR-09-2305
Published: 11 November 2009
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Lymphocytic Reaction to Colorectal Cancer Is Associated with Longer Survival, Independent of Lymph Node Count, Microsatellite Instability, and CpG Island Methylator Phenotype

Shuji Ogino, Katsuhiko Nosho, Natsumi Irahara, Jeffrey A. Meyerhardt, Yoshifumi Baba, Kaori Shima, Jonathan N. Glickman, Cristina R. Ferrone, Mari Mino-Kenudson, Noriko Tanaka, Glenn Dranoff, Edward L. Giovannucci, Charles S. Fuchs
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (20): 6412–6420.
DOI: https://doi.org/10.1158/1078-0432.CCR-09-1438
Published: 14 October 2009
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Interaction of Molecular Markers and Physical Activity on Mortality in Patients with Colon Cancer

Jeffrey A. Meyerhardt, Shuji Ogino, Gregory J. Kirkner, Andrew T. Chan, Brian Wolpin, Kimmie Ng, Katsuhiko Nosho, Kaori Shima, Edward L. Giovannucci, Massimo Loda, Charles S. Fuchs
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (18): 5931–5936.
DOI: https://doi.org/10.1158/1078-0432.CCR-09-0496
Published: 14 September 2009
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Relationship of CDX2 Loss with Molecular Features and Prognosis in Colorectal Cancer

Yoshifumi Baba, Katsuhiko Nosho, Kaori Shima, Ellen Freed, Natsumi Irahara, Juliet Philips, Jeffrey A. Meyerhardt, Jason L. Hornick, Ramesh A. Shivdasani, Charles S. Fuchs, Shuji Ogino
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (14): 4665–4673.
DOI: https://doi.org/10.1158/1078-0432.CCR-09-0401
Published: 15 July 2009
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A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases

Shuji Ogino, Katsuhiko Nosho, Natsumi Irahara, Shoko Kure, Kaori Shima, Yoshifumi Baba, Saori Toyoda, Li Chen, Edward L. Giovannucci, Jeffrey A. Meyerhardt, Charles S. Fuchs
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (13): 4431–4438.
DOI: https://doi.org/10.1158/1078-0432.CCR-08-3330
Published: 01 July 2009
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O6-Methylguanine DNA Methyltransferase Deficiency and Response to Temozolomide-Based Therapy in Patients with Neuroendocrine Tumors

Matthew H. Kulke, Jason L. Hornick, Christine Frauenhoffer, Susanne Hooshmand, David P. Ryan, Peter C. Enzinger, Jeffrey A. Meyerhardt, Jeffrey W. Clark, Keith Stuart, Charles S. Fuchs, Mark S. Redston
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (1): 338–345.
DOI: https://doi.org/10.1158/1078-0432.CCR-08-1476
Published: 31 December 2008
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Plasma Insulin-like Growth Factors, Insulin-like Binding Protein-3, and Outcome in Metastatic Colorectal Cancer: Results from Intergroup Trial N9741

Charles S. Fuchs, Richard M. Goldberg, Daniel J. Sargent, Jeffrey A. Meyerhardt, Brian M. Wolpin, Erin M. Green, Henry C. Pitot, Michael Pollak
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (24): 8263–8269.
DOI: https://doi.org/10.1158/1078-0432.CCR-08-0480
Published: 15 December 2008
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