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Jeffrey A. Meyerhardt
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Journal Articles

RAS/RAF Comutation and ERBB2 Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer

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Harshabad Singh, Pranshu Sahgal, Kevin Kapner, Steven M. Corsello, Hersh Gupta, Rahul Gujrathi, Yvonne Y. Li, Andrew D. Cherniack, Raquelle El Alam, Joseph Kerfoot, Elizabeth Andrews, Annette Lee, Chetan Nambiar, Alison M. Hannigan, Joshua Remland, Lauren Brais, Meghan E. Leahy, Douglas A. Rubinson, Benjamin L. Schlechter, Matthew Meyerson, Yanan Kuang, Cloud P. Paweletz, Jessica K. Lee, Julia C.F. Quintanilha, Andrew J. Aguirre, Kimberly J. Perez, Brandon M. Huffman, Humberto Rossi, Thomas A. Abrams, Sheheryar Kabraji, Livio Trusolino, Andrea Bertotti, Ewa T. Sicinska, Aparna R. Parikh, Brian M. Wolpin, Alexa B. Schrock, Marios Giannakis, Kimmie Ng, Jeffrey A. Meyerhardt, Jason L. Hornick, Nilay S. Sethi, James M. Cleary
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (8): 1669–1684.
https://doi.org/10.1158/1078-0432.CCR-23-2581
Published: 15 April 2024
View articletitled, RAS/RAF Comutation and ERBB2 Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Plasma 25-Hydroxyvitamin D Levels and Survival in Stage III Colon Cancer: Findings from CALGB/SWOG 80702 (Alliance)

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Qiao-Li Wang, Chao Ma, Chen Yuan, Qian Shi, Brian M. Wolpin, Yin Zhang, Charles S. Fuchs, Jeffrey Meyer, Tyler Zemla, En Cheng, Priya Kumthekar, Katherine A. Guthrie, Felix Couture, Philip Kuebler, Pankaj Kumar, Benjamin Tan, Smitha Krishnamurthi, Richard M. Goldberg, Alan Venook, Charles Blanke, Anthony F. Shields, Eileen M. O'Reilly, Jeffrey A. Meyerhardt, Kimmie Ng
Journal: Clinical Cancer Research
Clin Cancer Res (2023) 29 (14): 2621–2630.
https://doi.org/10.1158/1078-0432.CCR-23-0447
Published: 14 July 2023
View articletitled, Plasma 25-Hydroxyvitamin D Levels and Survival in Stage III Colon Cancer: Findings from CALGB/SWOG 80702 (Alliance)
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Includes: Supplementary data
Journal Articles

Plasma Protein Biomarkers in Advanced or Metastatic Colorectal Cancer Patients Receiving Chemotherapy With Bevacizumab or Cetuximab: Results from CALGB 80405 (Alliance)

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Andrew B. Nixon, Alexander B. Sibley, Yingmiao Liu, Ace J. Hatch, Chen Jiang, Flora Mulkey, Mark D. Starr, John C. Brady, Donna Niedzwiecki, Alan P. Venook, Luis Baez-Diaz, Heinz-Josef Lenz, Bert H. O'Neil, Federico Innocenti, Jeffrey A. Meyerhardt, Eileen M. O'Reilly, Kouros Owzar, Herbert I. Hurwitz
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (13): 2779–2788.
https://doi.org/10.1158/1078-0432.CCR-21-2389
Published: 01 July 2022
View articletitled, Plasma Protein Biomarkers in Advanced or Metastatic Colorectal Cancer Patients Receiving Chemotherapy With Bevacizumab or Cetuximab: Results from CALGB 80405 (Alliance)
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Includes: Supplementary data
Journal Articles

Association of Fusobacterium nucleatum with Specific T-cell Subsets in the Colorectal Carcinoma Microenvironment

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Jennifer Borowsky, Koichiro Haruki, Mai Chan Lau, Andressa Dias Costa, Juha P. Väyrynen, Tomotaka Ugai, Kota Arima, Annacarolina da Silva, Kristen D. Felt, Melissa Zhao, Carino Gurjao, Tyler S. Twombly, Kenji Fujiyoshi, Sara A. Väyrynen, Tsuyoshi Hamada, Kosuke Mima, Susan Bullman, Tabitha A. Harrison, Amanda I. Phipps, Ulrike Peters, Kimmie Ng, Jeffrey A. Meyerhardt, Mingyang Song, Edward L. Giovannucci, Kana Wu, Xuehong Zhang, Gordon J. Freeman, Curtis Huttenhower, Wendy S. Garrett, Andrew T. Chan, Barbara A. Leggett, Vicki L.J. Whitehall, Neal Walker, Ian Brown, Mark Bettington, Reiko Nishihara, Charles S. Fuchs, Jochen K. Lennerz, Marios Giannakis, Jonathan A. Nowak, Shuji Ogino
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (10): 2816–2826.
https://doi.org/10.1158/1078-0432.CCR-20-4009
Published: 15 May 2021
View articletitled, Association of Fusobacterium nucleatum with Specific T-cell Subsets in the Colorectal Carcinoma Microenvironment
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Includes: Supplementary data
Journal Articles

Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions

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Harshabad Singh, Yvonne Y. Li, Liam F. Spurr, Atul B. Shinagare, Ritika Abhyankar, Emma Reilly, Lauren K. Brais, Anwesha Nag, Matthew D. Ducar, Aaron R. Thorner, Geoffrey I. Shapiro, Rachel B. Keller, Cheta Siletti, Jeffrey W. Clark, Anna F. Farago, Jessica J. Lin, George D. Demetri, Rahul Gujrathi, Matthew H. Kulke, Laura E. MacConaill, Azra H. Ligon, Ewa Sicinska, Matthew L. Meyerson, Jeffrey A. Meyerhardt, Andrew D. Cherniack, Brian M. Wolpin, Kimmie Ng, Marios Giannakis, Jason L. Hornick, James M. Cleary
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (6): 1695–1705.
https://doi.org/10.1158/1078-0432.CCR-20-4073
Published: 15 March 2021
View articletitled, Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions
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Includes: Supplementary data
Journal Articles

Prognostic Significance of Immune Cell Populations Identified by Machine Learning in Colorectal Cancer Using Routine Hematoxylin and Eosin–Stained Sections

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Juha P. Väyrynen, Mai Chan Lau, Koichiro Haruki, Sara A. Väyrynen, Andressa Dias Costa, Jennifer Borowsky, Melissa Zhao, Kenji Fujiyoshi, Kota Arima, Tyler S. Twombly, Junko Kishikawa, Simeng Gu, Saina Aminmozaffari, Shanshan Shi, Yoshifumi Baba, Naohiko Akimoto, Tomotaka Ugai, Annacarolina Da Silva, Mingyang Song, Kana Wu, Andrew T. Chan, Reiko Nishihara, Charles S. Fuchs, Jeffrey A. Meyerhardt, Marios Giannakis, Shuji Ogino, Jonathan A. Nowak
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (16): 4326–4338.
https://doi.org/10.1158/1078-0432.CCR-20-0071
Published: 14 August 2020
View articletitled, Prognostic Significance of Immune Cell Populations Identified by Machine Learning in Colorectal Cancer Using Routine Hematoxylin and Eosin–Stained Sections
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Includes: Supplementary data
Journal Articles

Plasma 25-Hydroxyvitamin D Levels and Survival in Patients with Advanced or Metastatic Colorectal Cancer: Findings from CALGB/SWOG 80405 (Alliance)

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Chen Yuan, Kaori Sato, Bruce W. Hollis, Sui Zhang, Donna Niedzwiecki, Fang-Shu Ou, I-Wen Chang, Bert H. O'Neil, Federico Innocenti, Heinz-Josef Lenz, Charles D. Blanke, Richard M. Goldberg, Alan P. Venook, Robert J. Mayer, Charles S. Fuchs, Jeffrey A. Meyerhardt, Kimmie Ng
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (24): 7497–7505.
https://doi.org/10.1158/1078-0432.CCR-19-0877
Published: 13 December 2019
View articletitled, Plasma 25-Hydroxyvitamin D Levels and Survival in Patients with Advanced or Metastatic Colorectal Cancer: Findings from CALGB/SWOG 80405 (Alliance)
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Includes: Supplementary data
Journal Articles

Calcium Intake and Survival after Colorectal Cancer Diagnosis

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Wanshui Yang, Yanan Ma, Stephanie Smith-Warner, Mingyang Song, Kana Wu, Molin Wang, Andrew T. Chan, Shuji Ogino, Charles S. Fuchs, Vitaliy Poylin, Kimmie Ng, Jeffrey A. Meyerhardt, Edward L. Giovannucci, Xuehong Zhang
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (6): 1980–1988.
https://doi.org/10.1158/1078-0432.CCR-18-2965
Published: 15 March 2019
View articletitled, Calcium Intake and Survival after Colorectal Cancer Diagnosis
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Includes: Supplementary data
Journal Articles

MicroRNA MIR21 (miR-21) and PTGS2 Expression in Colorectal Cancer and Patient Survival

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Kosuke Mima, Reiko Nishihara, Juhong Yang, Ruoxu Dou, Yohei Masugi, Yan Shi, Annacarolina da Silva, Yin Cao, Mingyang Song, Jonathan Nowak, Mancang Gu, Wanwan Li, Teppei Morikawa, Xuehong Zhang, Kana Wu, Hideo Baba, Edward L. Giovannucci, Jeffrey A. Meyerhardt, Andrew T. Chan, Charles S. Fuchs, Zhi Rong Qian, Shuji Ogino
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (15): 3841–3848.
https://doi.org/10.1158/1078-0432.CCR-15-2173
Published: 31 July 2016
View articletitled, MicroRNA MIR21 (miR-21) and PTGS2 Expression in Colorectal Cancer and Patient Survival
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Includes: Supplementary data
Journal Articles

Prognostic Utility of Molecular Factors by Age at Diagnosis of Colorectal Cancer

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Nadine J. McCleary, Kaori Sato, Reiko Nishihara, Kentaro Inamura, Teppei Morikawa, Xuehong Zhang, Kana Wu, Mai Yamauchi, Sun A. Kim, Yasutaka Sukawa, Kosuke Mima, Zhi Rong Qian, Charles S. Fuchs, Shuji Ogino, Jeffrey A. Meyerhardt
Journal: Clinical Cancer Research
Clin Cancer Res (2016) 22 (6): 1489–1498.
https://doi.org/10.1158/1078-0432.CCR-15-0946
Published: 14 March 2016
View articletitled, Prognostic Utility of Molecular Factors by Age at Diagnosis of Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Efficacy, Safety, Pharmacokinetics, and Biomarkers of Cediranib Monotherapy in Advanced Hepatocellular Carcinoma: A Phase II Study

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Andrew X. Zhu, Marek Ancukiewicz, Jeffrey G. Supko, Dushyant V. Sahani, Lawrence S. Blaszkowsky, Jeffrey A. Meyerhardt, Thomas A. Abrams, Nadine Jackson McCleary, Pankaj Bhargava, Alona Muzikansky, Susan Sheehan, Eileen Regan, Eamala Vasudev, Michelle Knowles, Charles S. Fuchs, David P. Ryan, Rakesh K. Jain, Dan G. Duda
Journal: Clinical Cancer Research
Clin Cancer Res (2013) 19 (6): 1557–1566.
https://doi.org/10.1158/1078-0432.CCR-12-3041
Published: 14 March 2013
View articletitled, Efficacy, Safety, Pharmacokinetics, and Biomarkers of Cediranib Monotherapy in Advanced Hepatocellular Carcinoma: A Phase II Study
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Includes: Supplementary data
Journal Articles

Specific Mutations in KRAS Codons 12 and 13, and Patient Prognosis in 1075 BRAF Wild-Type Colorectal Cancers

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Yu Imamura, Teppei Morikawa, Xiaoyun Liao, Paul Lochhead, Aya Kuchiba, Mai Yamauchi, Zhi Rong Qian, Reiko Nishihara, Jeffrey A. Meyerhardt, Kevin M. Haigis, Charles S. Fuchs, Shuji Ogino
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (17): 4753–4763.
https://doi.org/10.1158/1078-0432.CCR-11-3210
Published: 30 August 2012
View articletitled, Specific Mutations in KRAS Codons 12 and 13, and Patient Prognosis in 1075 BRAF Wild-Type Colorectal Cancers
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Includes: Supplementary data
Journal Articles

Prognostic Role of PIK3CA Mutation in Colorectal Cancer: Cohort Study and Literature Review

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Xiaoyun Liao, Teppei Morikawa, Paul Lochhead, Yu Imamura, Aya Kuchiba, Mai Yamauchi, Katsuhiko Nosho, Zhi Rong Qian, Reiko Nishihara, Jeffrey A. Meyerhardt, Charles S. Fuchs, Shuji Ogino
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (8): 2257–2268.
https://doi.org/10.1158/1078-0432.CCR-11-2410
Published: 16 April 2012
View articletitled, Prognostic Role of PIK3CA Mutation in Colorectal Cancer: Cohort Study and Literature Review
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Includes: Supplementary data
Journal Articles

Predictive and Prognostic Roles of BRAF Mutation in Stage III Colon Cancer: Results from Intergroup Trial CALGB 89803

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Shuji Ogino, Kaori Shima, Jeffrey A. Meyerhardt, Nadine J. McCleary, Kimmie Ng, Donna Hollis, Leonard B. Saltz, Robert J. Mayer, Paul Schaefer, Renaud Whittom, Alexander Hantel, Al B. Benson, III, Donna Spiegelman, Richard M. Goldberg, Monica M. Bertagnolli, Charles S. Fuchs
Journal: Clinical Cancer Research
Clin Cancer Res (2012) 18 (3): 890–900.
https://doi.org/10.1158/1078-0432.CCR-11-2246
Published: 31 January 2012
View articletitled, Predictive and Prognostic Roles of BRAF Mutation in Stage III Colon Cancer: Results from Intergroup Trial CALGB 89803
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Includes: Supplementary data
Journal Articles

KRAS Mutation in Stage III Colon Cancer and Clinical Outcome Following Intergroup Trial CALGB 89803

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Shuji Ogino, Jeffrey A. Meyerhardt, Natsumi Irahara, Donna Niedzwiecki, Donna Hollis, Leonard B. Saltz, Robert J. Mayer, Paul Schaefer, Renaud Whittom, Alexander Hantel, Al B. Benson, III, Richard M. Goldberg, Monica M. Bertagnolli, Charles S. Fuchs, for the Cancer and Leukemia Group B, North Central Cancer Treatment Group, Canadian Cancer Society Research Institute, Southwest Oncology Group
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (23): 7322–7329.
https://doi.org/10.1158/1078-0432.CCR-09-1570
Published: 30 November 2009
View articletitled, KRAS Mutation in Stage III Colon Cancer and Clinical Outcome Following Intergroup Trial CALGB 89803
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Journal Articles

Getting Knit-PI3Ky: PIK3CA Mutation Status to Direct Multimodality Therapy?

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Andrea P. Myers, Jeffrey A. Meyerhardt, Lewis C. Cantley
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (22): 6748–6750.
https://doi.org/10.1158/1078-0432.CCR-09-2305
Published: 11 November 2009
View articletitled, Getting Knit-PI3Ky: PIK3CA Mutation Status to Direct Multimodality Therapy?
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Includes: Supplementary data
Journal Articles

Lymphocytic Reaction to Colorectal Cancer Is Associated with Longer Survival, Independent of Lymph Node Count, Microsatellite Instability, and CpG Island Methylator Phenotype

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Shuji Ogino, Katsuhiko Nosho, Natsumi Irahara, Jeffrey A. Meyerhardt, Yoshifumi Baba, Kaori Shima, Jonathan N. Glickman, Cristina R. Ferrone, Mari Mino-Kenudson, Noriko Tanaka, Glenn Dranoff, Edward L. Giovannucci, Charles S. Fuchs
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (20): 6412–6420.
https://doi.org/10.1158/1078-0432.CCR-09-1438
Published: 14 October 2009
View articletitled, Lymphocytic Reaction to Colorectal Cancer Is Associated with Longer Survival, Independent of Lymph Node Count, Microsatellite Instability, and CpG Island Methylator Phenotype
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Includes: Supplementary data
Journal Articles

Interaction of Molecular Markers and Physical Activity on Mortality in Patients with Colon Cancer

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Jeffrey A. Meyerhardt, Shuji Ogino, Gregory J. Kirkner, Andrew T. Chan, Brian Wolpin, Kimmie Ng, Katsuhiko Nosho, Kaori Shima, Edward L. Giovannucci, Massimo Loda, Charles S. Fuchs
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (18): 5931–5936.
https://doi.org/10.1158/1078-0432.CCR-09-0496
Published: 14 September 2009
View articletitled, Interaction of Molecular Markers and Physical Activity on Mortality in Patients with Colon Cancer
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Journal Articles

Relationship of CDX2 Loss with Molecular Features and Prognosis in Colorectal Cancer

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Yoshifumi Baba, Katsuhiko Nosho, Kaori Shima, Ellen Freed, Natsumi Irahara, Juliet Philips, Jeffrey A. Meyerhardt, Jason L. Hornick, Ramesh A. Shivdasani, Charles S. Fuchs, Shuji Ogino
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (14): 4665–4673.
https://doi.org/10.1158/1078-0432.CCR-09-0401
Published: 15 July 2009
View articletitled, Relationship of CDX2 Loss with Molecular Features and Prognosis in Colorectal Cancer
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Journal Articles

A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases

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Shuji Ogino, Katsuhiko Nosho, Natsumi Irahara, Shoko Kure, Kaori Shima, Yoshifumi Baba, Saori Toyoda, Li Chen, Edward L. Giovannucci, Jeffrey A. Meyerhardt, Charles S. Fuchs
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (13): 4431–4438.
https://doi.org/10.1158/1078-0432.CCR-08-3330
Published: 01 July 2009
View articletitled, A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases
Open the PDF for A Cohort Study of Cyclin D1 Expression and Prognosis in 602 Colon Cancer Cases in another window
Includes: Supplementary data