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Jean-Pierre Issa
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Journal Articles

Safety, Outcomes, and T-Cell Characteristics in Patients with Relapsed or Refractory MDS or CMML Treated with Atezolizumab in Combination with Guadecitabine

Casey L. O'Connell, Maria R. Baer, Andreas Due Ørskov, Sunil Kumar Saini, Vu H. Duong, Patricia Kropf, Jakob Werner Hansen, Denice Tsao-Wei, Hyo Sik Jang, Ashkan Emadi, Staffan Holmberg-Thyden, Jack Cowland, Brett T. Brinker, Kristin Horwood, Ryan Burgos, Galen Hostetter, Benjamin A. Youngblood, Sine Reker Hadrup, Jean-Pierre Issa, Peter Jones, Stephen B. Baylin, Imran Siddiqi, Kirsten Grønbaek
Journal: Clinical Cancer Research
Clin Cancer Res (2022) 28 (24): 5306–5316.
https://doi.org/10.1158/1078-0432.CCR-22-1810
Published: 15 December 2022
View article titled, Safety, Outcomes, and T-Cell Characteristics in Patients with Relapsed or Refractory MDS or CMML Treated with Atezolizumab in Combination with Guadecitabine
Open the PDF for Safety, Outcomes, and T-Cell Characteristics in Patients with Relapsed or Refractory MDS or CMML Treated with Atezolizumab in Combination with Guadecitabine in another window
Includes: Supplementary data
Journal Articles

5-azacytidine(5- AC), all-trans retinoic acid (ATRA), and valproic acid (VPA) in patients with acute myelogenous leukemia (AML): Molecular and clinical implications

Andres Soriano, Hui Yang, Srdan Verstovsek, William Wierda, Charles Koller, Zeev Estrov, Souzanne Ouzounian, Hagop Kantarjian, Jean Pierre Issa, Guillermo Garcia-Manero
Journal: Clinical Cancer Research
Clin Cancer Res (2006) 12 (19_Supplement): B48.
Published: 15 August 2014
View article titled, 5-azacytidine(5- AC), all-trans retinoic acid (ATRA), and valproic acid (VPA) in patients with acute myelogenous leukemia (AML): Molecular and clinical implications
Journal Articles

Identification of Differentially Methylated Genes in Normal Prostate Tissues from African American and Caucasian Men

Bernard Kwabi-Addo, Songping Wang, Woonbok Chung, Jaroslav Jelinek, Steven R. Patierno, Bi-Dar Wang, Ramez Andrawis, Norman H. Lee, Victor Apprey, Jean-Pierre Issa, Michael Ittmann
Journal: Clinical Cancer Research
Clin Cancer Res (2010) 16 (14): 3539–3547.
https://doi.org/10.1158/1078-0432.CCR-09-3342
Published: 14 July 2010
View article titled, Identification of Differentially Methylated Genes in Normal Prostate Tissues from African American and Caucasian Men
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Includes: Supplementary data
Journal Articles

Decitabine Effect on Tumor Global DNA Methylation and Other Parameters in a Phase I Trial in Refractory Solid Tumors and Lymphomas

David J. Stewart, Jean-Pierre Issa, Razelle Kurzrock, Maria I. Nunez, Jaroslav Jelinek, David Hong, Yasuhiro Oki, Zhong Guo, Sanjay Gupta, Ignacio I. Wistuba
Journal: Clinical Cancer Research
Clin Cancer Res (2009) 15 (11): 3881–3888.
https://doi.org/10.1158/1078-0432.CCR-08-2196
Published: 01 June 2009
View article titled, Decitabine Effect on Tumor Global DNA Methylation and Other Parameters in a Phase I Trial in Refractory Solid Tumors and Lymphomas
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Journal Articles

Colon Cancer: It's CIN or CIMP

Jean-Pierre Issa
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (19): 5939–5940.
https://doi.org/10.1158/1078-0432.CCR-08-1596
Published: 30 September 2008
View article titled, Colon Cancer: It's CIN or CIMP
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Includes: Supplementary data
Journal Articles

Quantitative Promoter Hypermethylation Analysis of Cancer-Related Genes in Salivary Gland Carcinomas: Comparison with Methylation-Specific PCR Technique and Clinical Significance

Eung-Seok Lee, Jean-Pierre Issa, Dianna B. Roberts, Michelle D. Williams, Randal S. Weber, Merrill S. Kies, Adel K. El-Naggar
Journal: Clinical Cancer Research
Clin Cancer Res (2008) 14 (9): 2664–2672.
https://doi.org/10.1158/1078-0432.CCR-07-1232
Published: 01 May 2008
View article titled, Quantitative Promoter Hypermethylation Analysis of Cancer-Related Genes in Salivary Gland Carcinomas: Comparison with Methylation-Specific PCR Technique and Clinical Significance
Open the PDF for Quantitative Promoter Hypermethylation Analysis of Cancer-Related Genes in Salivary Gland Carcinomas: Comparison with Methylation-Specific PCR Technique and Clinical Significance in another window
Journal Articles

Differing DNA Methylation Patterns and Gene Mutation Frequencies in Colorectal Carcinomas from Middle Eastern Countries

Annie O. Chan, Amr S. Soliman, Qing Zhang, Asif Rashid, Ahmed Bedeir, P. Scott Houlihan, Nadia Mokhtar, Nidal Al-Masri, Ugur Ozbek, Rami Yaghan, Ayten Kandilci, Sherif Omar, Yersu Kapran, Ferhunde Dizdaroglu, Melissa L. Bondy, Christopher I. Amos, Jean-Pierre Issa, Bernard Levin, Stanley R. Hamilton
Journal: Clinical Cancer Research
Clin Cancer Res (2005) 11 (23): 8281–8287.
https://doi.org/10.1158/1078-0432.CCR-05-1000
Published: 01 December 2005
View article titled, Differing DNA Methylation Patterns and Gene Mutation Frequencies in Colorectal Carcinomas from Middle Eastern Countries
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Journal Articles

Hypermethylation of the Retinoic Acid Receptor -β 2 Gene in Head and Neck Carcinogenesis

Emile M. Youssef, Dafna Lotan, Jean-Pierre Issa, Kenichi Wakasa, You-Hong Fan, Li Mao, Khaled Hassan, Lei Feng, J. Jack Lee, Scott M. Lippman, Waun K. Hong, Reuben Lotan
Journal: Clinical Cancer Research
Clin Cancer Res (2004) 10 (5): 1733–1742.
https://doi.org/10.1158/1078-0432.CCR-0989-3
Published: 10 March 2004
View article titled, Hypermethylation of the <em>Retinoic Acid Receptor</em> -β<sub> <em>2</em> </sub> Gene in Head and Neck Carcinogenesis
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Journal Articles

Lack of PTEN Expression in Non-Small Cell Lung Cancer Could Be Related to Promoter Methylation

Jean-Charles Soria, Ho-Young Lee, Janet I. Lee, Luo Wang, Jean-Pierre Issa, Bonnie L. Kemp, Diane D. Liu, Jonathan M. Kurie, Li Mao, Fadlo R. Khuri
Journal: Clinical Cancer Research
Clin Cancer Res (2002) 8 (5): 1178–1184.
Published: 01 May 2002
View article titled, Lack of PTEN Expression in Non-Small Cell Lung Cancer Could Be Related to Promoter Methylation
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