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Javier de Castro
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Journal Articles

ctDNA Dynamics and Mechanisms of Acquired Resistance in Patients Treated with Osimertinib with or without Bevacizumab from the Randomized Phase II ETOP-BOOSTER Trial

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Ross A. Soo, Urania Dafni, Ji-Youn Han, Byoung Chul Cho, Ernest Nadal, Chong Ming Yeo, Enric Carcereny, Javier de Castro, Maria Angeles Sala, Linda Coate, Mariano Provencio, Christian Britschgi, Patrick Vagenknecht, Georgia Dimopoulou, Roswitha Kammler, Stephen P. Finn, Solange Peters, Rolf A. Stahel, for the ETOP 10-16 BOOSTER Collaborators
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (22): 5180–5191.
https://doi.org/10.1158/1078-0432.CCR-24-0932
Published: 15 November 2024
View articletitled, ctDNA Dynamics and Mechanisms of Acquired Resistance in Patients Treated with Osimertinib with or without Bevacizumab from the Randomized Phase II ETOP-BOOSTER Trial
Open the PDF for ctDNA Dynamics and Mechanisms of Acquired Resistance in Patients Treated with Osimertinib with or without Bevacizumab from the Randomized Phase II ETOP-BOOSTER Trial in another window
Includes: Supplementary data
Journal Articles

Spatially Preserved Multi-Region Transcriptomic Subtyping and Biomarkers of Chemoimmunotherapy Outcome in Extensive-Stage Small Cell Lung Cancer

Available to Purchase
Melina Peressini, Rosario Garcia-Campelo, Bartomeu Massuti, Cristina Martí, Manuel Cobo, Vanesa Gutiérrez, Manuel Dómine, José Fuentes, Margarita Majem, Javier de Castro, Juan F. Córdoba, María P. Diz, Dolores Isla, Emilio Esteban, Enric Carcereny, Laia Vila, Alberto Moreno-Vega, Silverio Ros, Amaia Moreno, Francisco J. García, Gerardo Huidobro, Carlos Aguado, Victor Cebey-López, Javier Valdivia, Ramón Palmero, Pilar Lianes, Marta López-Brea, Oscar J. Vidal, Mariano Provencio, Edurne Arriola, Javier Baena, Mercedes Herrera, Helena Bote, Magdalena Molero, Vera Adradas, Santiago Ponce-Aix, Angel Nuñez-Buiza, Álvaro Ucero, Susana Hernandez, Fernando Lopez-Rios, Esther Conde, Luis Paz-Ares, Jon Zugazagoitia
Journal: Clinical Cancer Research
Clin Cancer Res (2024) 30 (14): 3036–3049.
https://doi.org/10.1158/1078-0432.CCR-24-0104
Published: 15 July 2024
View articletitled, Spatially Preserved Multi-Region Transcriptomic Subtyping and Biomarkers of Chemoimmunotherapy Outcome in Extensive-Stage Small Cell Lung Cancer
Open the PDF for Spatially Preserved Multi-Region Transcriptomic Subtyping and Biomarkers of Chemoimmunotherapy Outcome in Extensive-Stage Small Cell Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Pretreatment Tissue TCR Repertoire Evenness Is Associated with Complete Pathologic Response in Patients with NSCLC Receiving Neoadjuvant Chemoimmunotherapy

Open Access
Marta Casarrubios, Alberto Cruz-Bermúdez, Ernest Nadal, Amelia Insa, María del Rosario García Campelo, Martín Lázaro, Manuel Dómine, Margarita Majem, Delvys Rodríguez-Abreu, Alex Martínez-Martí, Javier de Castro-Carpeño, Manuel Cobo, Guillermo López-Vivanco, Edel Del Barco, Reyes Bernabé Caro, Nuria Viñolas, Isidoro Barneto Aranda, Santiago Viteri, Bartomeu Massuti, Miguel Barquín, Raquel Laza-Briviesca, Belén Sierra-Rodero, Edwin R. Parra, Beatriz Sanchez-Espiridion, Pedro Rocha, Humam Kadara, Ignacio I. Wistuba, Atocha Romero, Virginia Calvo, Mariano Provencio
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (21): 5878–5890.
https://doi.org/10.1158/1078-0432.CCR-21-1200
Published: 01 November 2021
View articletitled, Pretreatment Tissue TCR Repertoire Evenness Is Associated with Complete Pathologic Response in Patients with NSCLC Receiving Neoadjuvant Chemoimmunotherapy
Open the PDF for Pretreatment Tissue TCR Repertoire Evenness Is Associated with Complete Pathologic Response in Patients with NSCLC Receiving Neoadjuvant Chemoimmunotherapy in another window
Includes: Supplementary data
Journal Articles

Trastuzumab Emtansine (T-DM1) in Patients with Previously Treated HER2-Overexpressing Metastatic Non–Small Cell Lung Cancer: Efficacy, Safety, and Biomarkers

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Solange Peters, Rolf Stahel, Lukas Bubendorf, Philip Bonomi, Augusto Villegas, Dariusz M. Kowalski, Christina S. Baik, Dolores Isla, Javier De Castro Carpeno, Pilar Garrido, Achim Rittmeyer, Marcello Tiseo, Christoph Meyenberg, Sanne de Haas, Lisa H. Lam, Michael W. Lu, Thomas E. Stinchcombe
Journal: Clinical Cancer Research
Clin Cancer Res (2019) 25 (1): 64–72.
https://doi.org/10.1158/1078-0432.CCR-18-1590
Published: 03 January 2019
View articletitled, Trastuzumab Emtansine (T-DM1) in Patients with Previously Treated HER2-Overexpressing Metastatic Non–Small Cell Lung Cancer: Efficacy, Safety, and Biomarkers
Open the PDF for Trastuzumab Emtansine (T-DM1) in Patients with Previously Treated HER2-Overexpressing Metastatic Non–Small Cell Lung Cancer: Efficacy, Safety, and Biomarkers in another window
Includes: Supplementary data
Journal Articles

A Combined Strategy of SAGE and Quantitative PCR Provides a 13-Gene Signature that Predicts Preoperative Chemoradiotherapy Response and Outcome in Rectal Cancer

Available to Purchase
Enrique Casado, Victor Moreno García, Jose Javier Sánchez, Montserrat Blanco, Joan Maurel, Jaime Feliu, Carlos Fernández-Martos, Javier de Castro, Beatriz Castelo, Cristóbal Belda-Iniesta, María Sereno, Benito Sánchez-Llamas, Emilio Burgos, Miguel Ángel García-Cabezas, Noemí Manceñido, Rosa Miquel, Damián García-Olmo, Manuel González-Barón, Paloma Cejas
Journal: Clinical Cancer Research
Clin Cancer Res (2011) 17 (12): 4145–4154.
https://doi.org/10.1158/1078-0432.CCR-10-2257
Published: 15 June 2011
View articletitled, A Combined Strategy of SAGE and Quantitative PCR Provides a 13-Gene Signature that Predicts Preoperative Chemoradiotherapy Response and Outcome in Rectal Cancer
Open the PDF for A Combined Strategy of SAGE and Quantitative PCR Provides a 13-Gene Signature that Predicts Preoperative Chemoradiotherapy Response and Outcome in Rectal Cancer in another window
Includes: Supplementary data