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Jared M. Lucas
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Journal Articles

BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program

Dae-Hwan Kim, Duanchen Sun, William K. Storck, Katherine Welker Leng, Chelsea Jenkins, Daniel J. Coleman, David Sampson, Xiangnan Guan, Anbarasu Kumaraswamy, Eva S. Rodansky, Joshua A. Urrutia, Jacob A. Schwartzman, Chao Zhang, Himisha Beltran, Mark P. Labrecque, Colm Morrissey, Jared M. Lucas, Ilsa M. Coleman, Peter S. Nelson, Eva Corey, Samuel K. Handelman, Jonathan Z. Sexton, Rahul Aggarwal, Wassim Abida, Felix Y. Feng, Eric J. Small, Daniel E. Spratt, Armand Bankhead, III, Arvind Rao, Emily M. Gesner, Sarah Attwell, Sanjay Lakhotia, Eric Campeau, Joel A. Yates, Zheng Xia, Joshi J. Alumkal
Journal: Clinical Cancer Research
Clin Cancer Res (2021) 27 (17): 4923–4936.
https://doi.org/10.1158/1078-0432.CCR-20-4968
Published: 01 September 2021
View article titled, BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
Open the PDF for BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program in another window
Includes: Supplementary data
Journal Articles

Identification of Therapeutic Vulnerabilities in Small-cell Neuroendocrine Prostate Cancer

Alexandra N. Corella, Ma Victoria Andrea Cabiliza Ordonio, Ilsa Coleman, Jared M. Lucas, Arja Kaipainen, Holly M. Nguyen, Daniel Sondheim, Lisha G. Brown, Lawrence D. True, John K. Lee, David MacPherson, Paul Nghiem, Roman Gulati, Colm Morrissey, Eva Corey, Peter S. Nelson
Journal: Clinical Cancer Research
Clin Cancer Res (2020) 26 (7): 1667–1677.
https://doi.org/10.1158/1078-0432.CCR-19-0775
Published: 01 April 2020
View article titled, Identification of Therapeutic Vulnerabilities in Small-cell Neuroendocrine Prostate Cancer
Open the PDF for Identification of Therapeutic Vulnerabilities in Small-cell Neuroendocrine Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

Xiaotun Zhang, Ilsa M. Coleman, Lisha G. Brown, Lawrence D. True, Lori Kollath, Jared M. Lucas, Hung-Ming Lam, Ruth Dumpit, Eva Corey, Lisly Chéry, Bryce Lakely, Celestia S. Higano, Bruce Montgomery, Martine Roudier, Paul H. Lange, Peter S. Nelson, Robert L. Vessella, Colm Morrissey
Journal: Clinical Cancer Research
Clin Cancer Res (2015) 21 (20): 4698–4708.
https://doi.org/10.1158/1078-0432.CCR-15-0157
Published: 14 October 2015
View article titled, SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer
Open the PDF for SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer in another window
Includes: Supplementary data